KEGG   Geobacillus sp. GHH01: GHH_c06660
Entry
GHH_c06660        CDS       T02455                                 
Symbol
yitJ
Name
(GenBank) bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase
  KO
K24042  methionine synthase / methylenetetrahydrofolate reductase (NADH) [EC:2.1.1.13 1.5.1.54]
Organism
ggh  Geobacillus sp. GHH01
Pathway
ggh00270  Cysteine and methionine metabolism
ggh00450  Selenocompound metabolism
ggh00670  One carbon pool by folate
ggh01100  Metabolic pathways
ggh01110  Biosynthesis of secondary metabolites
ggh01120  Microbial metabolism in diverse environments
ggh01230  Biosynthesis of amino acids
Module
ggh_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:ggh00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    GHH_c06660 (yitJ)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    GHH_c06660 (yitJ)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    GHH_c06660 (yitJ)
Enzymes [BR:ggh01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.54  methylenetetrahydrofolate reductase (NADH)
     GHH_c06660 (yitJ)
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     GHH_c06660 (yitJ)
SSDB
Motif
Pfam: S-methyl_trans MTHFR DUF6506
Other DBs
NCBI-ProteinID: AGE21207
UniProt: L7ZVY0
Position
complement(652300..654147)
AA seq 615 aa
MGLLDELKERILIADGAMGTLLYSHGIDRCFEELNLSNPDEIVHIHEAYIAAGADVIQTN
TYGANYVKLARYGLEDEVPAINRAAVRLARQAANGRAYVLGTIGGLRTLNKSVVTLEEVK
RTFREQLFVLLAEGVDGVLLETYYDLEELETVLAIARKETDLPIIAHVSLHEVGVLQDGT
PLADALARLEALGADVVGLNCRLGPYHMLRSLEEVPLPKQAFLSAYPNASLPDYRDGRLV
YETNAEYFEETAKAFRDQGVRLIGGCCGTTPKHIAAMAKALSDRTPVTEKTVKRRAVSVS
VQADRPAPSPLPELARTRRSVIVELDPPKKLGIDKFLAGAKALHDAGIDALTLADNSLAT
PRISNAAVATIIKERLGVRPLVHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKIG
DFPGATSVYDLSSFDLIRLIRQFNEGLSYSGKPLGQKTNFSIGAAFNPNVRHLDKAVERM
EKKIQCGAHYFLTQPIYSEEKIVEVHEATKHLDTPIYIGIMPLVSARNADFLHHEVPGIT
LSDEIRARMAACSGDPVQAAKEGIAIAKSLIDAAFDLFNGIYLITPFLRYDMTVELVRYI
HEKEAAAKERKVVHG
NT seq 1848 nt   +upstreamnt  +downstreamnt
gtgggattgctggatgagttgaaagagcgcattctcatcgccgacggggcgatgggaacg
cttttatattcgcacggcattgaccgttgttttgaagaattgaatctatccaatccagat
gaaatcgtccatattcatgaagcgtatatcgccgcgggcgccgacgtcattcagacgaat
acatacggcgccaactatgtgaaactcgcccgctacggccttgaagatgaggtgccggcc
atcaaccgcgcggcggtgcggctcgccaggcaagcggcgaacgggcgggcgtacgtgctc
gggacgatcggggggctgcgcacgttaaacaaaagcgtcgtcacgctcgaagaagtgaaa
cggacgtttcgcgagcagctgtttgtcctgctggctgaaggggttgatggcgtgctgctc
gagacgtattacgatttggaagagttggagacggtgcttgccatcgcccgcaaagaaacg
gatttgccgatcatcgcccatgtgtcgctccatgaagtcggcgtcttgcaagatggcacg
ccgctcgcggacgcccttgctcgcctagaggcgctcggggccgatgtcgtcggactgaac
tgtcgtctcggtccatatcatatgcttcggtcgctcgaggaagtgccgctgccgaagcag
gcgtttttgtcggcgtatccgaacgccagcctcccggattaccgcgatggccggcttgtc
tatgagacgaacgctgaatatttcgaggaaacagccaaagcgttccgcgaccaaggggtg
cgcttgatcggcgggtgctgcggcacgacgccgaagcatatcgcagcgatggcaaaagcg
ctctccgaccgaacgccggtgacggaaaaaacggtgaaacggcgcgccgtgtctgtatca
gtgcaagcggatcggcccgccccatctccccttcccgagcttgcccgcacgcgccgctcg
gtcattgtggagctggatccgccgaaaaaattggggattgacaagtttcttgctggggcg
aaagcgctccatgacgccggcatcgatgcgctgacgttggccgacaactcgctcgccacg
ccgcgcatcagcaacgccgctgtcgccacgatcatcaaggagcggctcggcgtccgcccg
cttgtgcatattacatgccgcgatcgcaatttgatcggcttgcagtcgcatttgatgggc
ttgcatacgctcggcatcaccgatgtgctcgccattaccggcgacccgtcgaaaatcggc
gacttcccaggagcaacgtcggtgtatgatttatcatcgttcgatttgatccgcttgatc
cgccagtttaacgaagggctgtcgtactcgggcaaaccgcttgggcaaaaaacgaacttc
tcgatcggcgctgcgttcaacccgaacgtccgccatttggataaagcagttgagcgaatg
gagaaaaaaattcaatgcggcgcccactatttcttgacccagccgatttactcggaagag
aaaatcgttgaagtgcacgaagcgaccaagcatcttgacacaccgatttacatcggcatt
atgccgcttgtgagcgcgcgcaacgccgactttttgcatcatgaagtgccgggcattacg
ctctctgacgagattcgcgcccgcatggccgcctgcagcggtgacccggtgcaagcagcc
aaggaaggcatcgctatcgccaaatcgctcattgacgctgcgtttgatttgtttaacggc
atttatttgatcacgccgttcttgcgctacgacatgacggtcgagctcgtccgctacatt
cacgaaaaagaagcggccgccaaagaaaggaaggttgttcatggctaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (8)   
   KEGG PATHWAY (7)   
   KEGG MODULE (1)   
Chemical substance (12)   
   KEGG COMPOUND (12)   
Chemical reaction (5)   
   KEGG ENZYME (2)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (3)   
   Pfam (3)   
All databases (35)   

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