KEGG   Geobacillus sp. GHH01: GHH_c27350
Entry
GHH_c27350        CDS       T02455                                 
Symbol
leuB
Name
(GenBank) 3-isopropylmalate dehydrogenase
  KO
K00052  3-isopropylmalate dehydrogenase [EC:1.1.1.85]
Organism
ggh  Geobacillus sp. GHH01
Pathway
ggh00290  Valine, leucine and isoleucine biosynthesis
ggh00660  C5-Branched dibasic acid metabolism
ggh01100  Metabolic pathways
ggh01110  Biosynthesis of secondary metabolites
ggh01210  2-Oxocarboxylic acid metabolism
ggh01230  Biosynthesis of amino acids
Module
ggh_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:ggh00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00660 C5-Branched dibasic acid metabolism
    GHH_c27350 (leuB)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    GHH_c27350 (leuB)
Enzymes [BR:ggh01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.85  3-isopropylmalate dehydrogenase
     GHH_c27350 (leuB)
SSDB
Motif
Pfam: Iso_dh TAP42
Other DBs
NCBI-ProteinID: AGE23246
UniProt: L8A2G3
Position
complement(2726863..2727978)
AA seq 371 aa
MGNYRIAVLPGDGIGKEVTSGAVEVLKAVGIRFGHEFTFEYGLIGGAAIDEAGTPLPEET
LRLCRESDAVLLGAVGGPKWDDNPPHLRPEKGLLAIRKQLDLYANLRPVVCYDSLVSASP
LKPDLVQGVDFVIVRELTGGIYFGQPSGRVVENGEEKAVDTLLYKKEEIERIVRMAFILA
RGRKKKVTSVDKANVLSSSRLWREVAEEVAKQFPDVTLEHMLVDNAAMQLIRAPKQFDVI
VTENMFGDILSDEASMLSGSLGMLPSASLSASGPSLYEPVHGSAPDIAGMNKANPIAAIL
SAAMMLRLSFGLTAEAEAVEHAVRQALDQGLRTADLAPSGGRIVSTNEMVEEIKTAVLDY
TAIAQIMTVYA
NT seq 1116 nt   +upstreamnt  +downstreamnt
atgggaaactatcggattgccgtcttgccaggggatggcatcggaaaagaagtgacgtcc
ggagcggtcgaggtattgaaagcggtcggcatccggtttggccacgagtttacgtttgaa
tatggattgatcggtggagcggcgatcgatgaggcggggacgccgctccccgaggaaacg
ctccgcctttgccgagaaagcgatgcggtgctgcttggggcggtcggcggtccgaagtgg
gatgacaaccctccgcatttgcgcccggaaaaaggattgcttgccattcgcaagcagctc
gacttatatgccaacttgcggccggttgtttgctatgacagtttggtttccgcttcgccg
ttaaaaccggatctcgtgcaaggcgtcgattttgtcatcgtccgcgagctgaccggcggc
atttacttcggccagccgagcggccgcgtcgtcgaaaacggcgaagaaaaagcagtggac
accttgctatataaaaaggaagaaattgagcggatcgtccgcatggcgtttatactcgca
cgcgggcggaagaaaaaagtgacttcggtcgacaaggcgaacgtcctttcgtcaagccgt
ctatggagggaagtggccgaagaggtggcgaagcagtttccggacgtcacgcttgagcat
atgcttgttgacaatgccgcgatgcagctcatccgtgcgccgaagcagtttgatgtcatt
gtgacagaaaacatgtttggcgacattttaagcgatgaagcctccatgttgtccggttcg
ctcgggatgctgccgtcagccagcttatccgcttccggtccgagcttgtatgagccggtg
cacggttcagcgcctgatatcgccggcatgaacaaagccaatccgattgcggcgattttg
tcagctgcgatgatgcttcgcctgtcgttcgggctcaccgcggaagcggaggcggtcgag
cacgcggtgcggcaggcgctcgatcaaggtttgcgcactgccgacttggcgccaagcggc
ggccgcatcgtatcaacgaacgaaatggtcgaagaaatcaaaacagcggtgctggattat
acggccattgctcaaattatgaccgtttatgcctaa

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