KEGG   Gorilla gorilla gorilla (western lowland gorilla): 101129346
Entry
101129346         CDS       T02442                                 
Symbol
PKLR
Name
(RefSeq) pyruvate kinase PKLR isoform X1
  KO
K12406  pyruvate kinase isozymes R/L [EC:2.7.1.40]
Organism
ggo  Gorilla gorilla gorilla (western lowland gorilla)
Pathway
ggo00010  Glycolysis / Gluconeogenesis
ggo00620  Pyruvate metabolism
ggo01100  Metabolic pathways
ggo01200  Carbon metabolism
ggo01230  Biosynthesis of amino acids
ggo04910  Insulin signaling pathway
ggo04930  Type II diabetes mellitus
ggo04932  Non-alcoholic fatty liver disease
ggo04950  Maturity onset diabetes of the young
Module
ggo_M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
ggo_M00002  Glycolysis, core module involving three-carbon compounds
Brite
KEGG Orthology (KO) [BR:ggo00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    101129346 (PKLR)
   00620 Pyruvate metabolism
    101129346 (PKLR)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    101129346 (PKLR)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    101129346 (PKLR)
   04950 Maturity onset diabetes of the young
    101129346 (PKLR)
   04932 Non-alcoholic fatty liver disease
    101129346 (PKLR)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:ggo04147]
    101129346 (PKLR)
Enzymes [BR:ggo01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.40  pyruvate kinase
     101129346 (PKLR)
Exosome [BR:ggo04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   101129346 (PKLR)
SSDB
Motif
Pfam: PK PK_C IMPDH HpcH_HpaI
Other DBs
NCBI-GeneID: 101129346
NCBI-ProteinID: XP_004026964
Ensembl: ENSGGOG00000001917
UniProt: G3S6L6
Position
1:complement(125900690..125911944)
AA seq 543 aa
MEGPAGYLRRASVAQLTQELGTAFFQQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSII
ATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAASPLSYRPV
AIALDTKGPEIRTGILQGGPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVV
PVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVLGSRKGVNLPGAQVDLPGLSEQDVRD
LRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSD
GIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDV
ANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDP
TEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRG
VFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVL
SIS
NT seq 1632 nt   +upstreamnt  +downstreamnt
atggaagggccagcggggtatctgcggcgggccagtgtggcccaactgacccaggagctg
ggcactgccttcttccagcagcagcagctgccagctgctatggcagacaccttcctggaa
cacctctgcctactggacattgattccgagcccgtggctgctcgcagtaccagcatcatt
gccaccatcgggccagcatctcgctccgtggagcgcctcaaggagatgatcaaggccggg
atgaacattgcgcgactcaacttctcccacggctcccacgagtaccatgctgagtccatc
gccaacgtccgggaggcggtggagagctttgcagcttccccactcagctaccggcccgtg
gccatcgccctggacaccaagggaccggagatccgcactgggatcctgcaggggggtcca
gagtcggaagtggagctggtgaagggctcccaggtgctggtgactgtggaccccgcgttc
cggacgcgggggaacgcgaacaccgtgtgggtggactaccccaatattgtccgggtcgtg
ccggtggggggccgcatctacattgacgacgggctcatctccctagtggtccagaaaatc
ggcccagagggactggtgacccaagtggagaacggcggcgtcctgggcagccggaagggc
gtgaacttgccaggggcccaggtggacttgcccgggctgtccgagcaggacgtccgagac
ctgcgcttcggggtggagcatggggtggacatcgtctttgcctcctttgtgcggaaagcc
agcgacgtggctgccgtcagggctgctctgggtccggaaggacacggcatcaagatcatc
agcaaaattgagaaccacgaaggcgtgaagaggtttgatgaaatcctggaggtgagcgac
ggcatcatggtggcacggggggacctaggcatcgagatcccagcagagaaggttttcctg
gctcagaagatgatgattgggcgctgcaacttggcgggcaagcctgttgtctgtgccaca
cagatgctggagagcatgattaccaagccccggccaacgagggcagagacaagcgatgtc
gccaacgctgtgctggatggggctgactgcatcatgctgtcaggggagactgccaagggc
aacttccctgtggaagcggtgaagatgcagcatgcgattgcccgggaggcagaggccgca
gtgtaccaccggcagctgtttgaggagctacgtcgggcagcgccactaagccgtgatccc
actgaggtcaccgcgattggtgctgtggaggctgccttcaagtgctgtgctgctgccatc
attgtgctgaccacaactggccgctcagcccagcttctgtctcggtaccgacctcgggca
gcagtcattgctgtcacccgctctgcccaggctgcccgccaggtccacttatgccgagga
gtcttccccttgctttaccgtgaacctccagaagccatctgggcagatgatgtagatcgc
cgggtgcaatttggcattgaaagtggaaagctccgtggcttcctccgtgttggagacctg
gtgattgtggtgacaggctggcgacctggctccggctacaccaacatcatgcgggtgcta
agcatatcctga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (11)   
   KEGG PATHWAY (9)   
   KEGG MODULE (2)   
Chemical substance (12)   
   KEGG COMPOUND (12)   
Chemical reaction (6)   
   KEGG ENZYME (1)   
   KEGG REACTION (5)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (4)   
   Pfam (4)   
All databases (45)   

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