KEGG   Gorilla gorilla gorilla (western lowland gorilla): 101148343
Entry
101148343         CDS       T02442                                 
Name
(RefSeq) aldo-keto reductase family 1 member C4
  KO
K00037  3alpha-hydroxysteroid 3-dehydrogenase / chlordecone reductase [EC:1.1.1.50 1.1.1.357 1.1.1.225]
Organism
ggo  Gorilla gorilla gorilla (western lowland gorilla)
Pathway
ggo00120  Primary bile acid biosynthesis
ggo00140  Steroid hormone biosynthesis
ggo01100  Metabolic pathways
ggo05208  Chemical carcinogenesis - reactive oxygen species
Module
ggo_M00104  Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate
ggo_M00977  C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:ggo00001]
 09100 Metabolism
  09103 Lipid metabolism
   00120 Primary bile acid biosynthesis
    101148343
   00140 Steroid hormone biosynthesis
    101148343
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    101148343
Enzymes [BR:ggo01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.50  3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
     101148343
    1.1.1.225  chlordecone reductase
     101148343
    1.1.1.357  3alpha-hydroxysteroid 3-dehydrogenase
     101148343
SSDB
Motif
Pfam: Aldo_ket_red
Other DBs
NCBI-GeneID: 101148343
NCBI-ProteinID: XP_004049055
UniProt: G3S0S4
Position
10:5220871..5243428
AA seq 323 aa
MDPKYQRVELNDGHFMPVLGFGTYAPPEVPRNKAVEVTKLAIEAGFRHIDSAYLYNNEEQ
VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPM
ALKPGETPLPKDENGKVIFDTVDLCATWEVMEKCKDAGLAKSIGVSNFNRRQLEMILNKP
GLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPV
LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENVQVFEFQLTSEDMKVLDGLN
RNYRYVAMDFLMDHPDYPFSDEY
NT seq 972 nt   +upstreamnt  +downstreamnt
atggatcccaaatatcagcgtgtggagctaaatgatggtcacttcatgcccgtattggga
tttggcacctatgcacctccagaggttccgaggaacaaagctgtggaggtcaccaaatta
gcaatagaagctggcttccgccatattgattctgcttatttatacaataatgaggagcag
gttggactggccatccgaagcaagattgcagatggcagtgtgaagagagaagacatattc
tacacttcaaagctttggtgcactttctttcaaccacagatggtccaaccagccttggaa
agctcactgaaaaaacttcaactggactatgttgacctctatcttcttcatttcccaatg
gctctcaagccaggtgagacgccactaccaaaagatgaaaatggaaaagtaatattcgac
acagtggatctctgtgccacatgggaggtcatggagaagtgtaaggatgcaggattggcc
aagtccatcggggtgtcaaacttcaaccgcaggcagctggagatgatcctcaacaagcca
ggactcaagtacaagcctgtctgcaaccaggtagaatgtcatccttacctcaaccagagc
aaactgctggatttctgcaagtcaaaagacattgttctggttgcccacagtgctctggga
acccaacgacataaactatgggtggacccaaactccccagttcttttggaggacccagtt
ctttgtgccttagcaaagaaacacaaacgaaccccagccctgattgccctgcgctaccag
ctgcagcgtggggttgtggtcctggccaagagctacaatgagcagcggatcagagagaac
gtccaggtttttgaattccagttgacatcagaggatatgaaagttctagatggtctaaac
agaaattatcgatatgttgccatggattttcttatggaccaccctgattatccattttca
gatgaatattag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (6)   
   KEGG PATHWAY (4)   
   KEGG MODULE (2)   
Chemical substance (29)   
   KEGG COMPOUND (29)   
Chemical reaction (26)   
   KEGG ENZYME (3)   
   KEGG REACTION (23)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (1)   
   Pfam (1)   
All databases (72)   

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