KEGG   Gekko japonicus (Schlegel's Japanese gecko): 107125949
Entry
107125949         CDS       T04299                                 
Symbol
ITPR2
Name
(RefSeq) inositol 1,4,5-trisphosphate receptor type 2
  KO
K04959  inositol 1,4,5-triphosphate receptor type 2
Organism
gja  Gekko japonicus (Schlegel's Japanese gecko)
Pathway
gja04020  Calcium signaling pathway
gja04070  Phosphatidylinositol signaling system
gja04114  Oocyte meiosis
gja04210  Apoptosis
gja04218  Cellular senescence
gja04270  Vascular smooth muscle contraction
gja04371  Apelin signaling pathway
gja04540  Gap junction
gja04621  NOD-like receptor signaling pathway
gja04625  C-type lectin receptor signaling pathway
gja04912  GnRH signaling pathway
Brite
KEGG Orthology (KO) [BR:gja00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    107125949 (ITPR2)
   04020 Calcium signaling pathway
    107125949 (ITPR2)
   04070 Phosphatidylinositol signaling system
    107125949 (ITPR2)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    107125949 (ITPR2)
   04210 Apoptosis
    107125949 (ITPR2)
   04218 Cellular senescence
    107125949 (ITPR2)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    107125949 (ITPR2)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    107125949 (ITPR2)
   04625 C-type lectin receptor signaling pathway
    107125949 (ITPR2)
  09152 Endocrine system
   04912 GnRH signaling pathway
    107125949 (ITPR2)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    107125949 (ITPR2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:gja04040]
    107125949 (ITPR2)
Ion channels [BR:gja04040]
 Ligand-gated channels
  IP3 receptor
   107125949 (ITPR2)
SSDB
Motif
Pfam: Ins145_P3_rec RYDR_ITPR MIR RIH_assoc Ion_trans Mis12 Sec2p C_GCAxxG_C_C
Other DBs
NCBI-GeneID: 107125949
NCBI-ProteinID: XP_015284919
Position
Un
AA seq 2701 aa
MSDKMSSFLYIGDIVSLYAEGSVNGFISTLGLVDDRCVVQPDAGDLCNPPKKFRDCLFKV
CPMNRYSAQKQYWKSKQAKQGNHTEAALLKKLQHAAELEQKQNECENRKLLGEIVKYSNV
IQLLHIKSNKYLTVNKRLPALLEKNAMRVSLDAAGNEGSWFYIQPFWKLRSEGDNIVVGD
KVVLMPVNAGQPLHASNIELLDNPGCKEVNAVNCNTSWKITLFMKYSCYREDVLKGGDVV
RLFHAEQEKFLTCDEYQKQQHIFLRTTLRQSATSATSSKALWEIEVVHHDPCRGGAGQWN
SLFRFKHLATGNYLAAEVRIASTEYSKECSSSYDGELLASKKKRQAGEKIMYTLVSVPHG
NDIASLFELDATTLQRADCLVPRNSYVRLRHLCTNTWVTSTNIPIDKDEERPVMLKIGTC
QTKEDKEAFAIVSVPLSEVRDLDFANDANKVLASSVKTLENGSISQNERRFATKLLEDLI
FFIADVPSNVQEVLDVVVTKPNRERQKLMREQNILAQIFGILKAPFKDKAGEGAMLRLED
LGDQRYAPYKYILRLCYRLLRHSQQDYRKNQEYIAKNFCIMQSQIGYDILAEDTITALLH
NNRKLLEKHITAKEIETFVNLLRRNREPRFLDYLSDLCVSNATAIPVTQELICKYMLNPG
NADILIRTKLVSMQVDGPMECSALSDDIDEEEVWLYWIDSNKEPHGKAIRHLAQEAKEGN
KSDLEVLTYYRYQLNLFARMCLDRQYLAINQISIQLSVDLILRCMSDESLPYDLRASFCR
LMLHMHVDRDPQETVVPVKYARLWTEIPTKITIHEYDSFTDSSRNDMKRKFALTMEFVEE
YLKEVVNQPFPFGDKDKNKLTFEVVHLARNLIYFGFYSFSELLRLTRTLLAILDIVQGPM
SSYLERLSKFQDGGNNVMRTIHGVGEMMTQMVLSRGSIFPLAAPEVPPSVHPSKQMGTVE
SEDITVMDTKLKIIEILQFILSVRLDYRISYMLSIYKKEFGESSETVDGSVASPPESPII
TSAVVPDIDEIAAQAETMFAGRKEKNAVQLDDEGGRTFLRVLIHLIMHDYPPLLSGALHL
LFKHFSQRAEVLQAFKQVQLLVSNQDVDNYKQIKADLDQLRLTVEKSELWVDKNSSYESG
ELGESQAKGGDEPIEESSILSPVQDGSKKPQIDSNKSNNYNIVMEILIRLSKLCVQNKKS
RNQQQRLLKNMGAHCVVLDLLQIPYEKTDEKMIEVMNLAHMFLQNFCRGNPQNQILLHKH
INLFLTPGLLEAETMRHIFTNNYHLCNEISERAVQHFVHCIETHGRHVEYLRFLQTIVKA
DGKYVKKCQDMVMTELVNGGEDVLVFYNDRASFPILLQMMCSERDRVDENGALAYHITLV
ELLAACTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYVNFVNHCYVDTEVEMK
EIYTSNHIWKLFENFLVDMARVCNTTTDRKHADTSLEKYVSEPVMNIVSGFFSSPFSDNT
TSLQTHQPVFIQLLQSAFRIYNCTWPNPTQKSSVESCIKTLAEVAKNRGIAIPVDLDSQV
NTLFMKSHTNMIQRAAMGWRMSARSGPRFKEALGGPAWDYRNIIEKLQDVVTSLEQQFSP
MMQAEFSVLVDVLRSPELLFPEGSDARIRCGAFMSKLINHTKRLMEKEEKLCIKILQTLR
EMLDEKNSFAEEGSNLRKILLNRYFKGDHGNSISGPVSSSYGKTAQGGGSFSGQDSDKSG
VSMHDIQCLLDKEGASELVTDVIVSTKNDRIFSEAILLGIALLEGGNTQIQYSFYHQLNE
QKKSEKFFKVLHDRMKTAQQEIRSTVTVNTVDLGTKKKDEDNDVTVSLPKKRVRDSNLHL
KEGMKGQLTEASTATSKAYCVYRREMDPEIDLISSGTDAANAEEKSSEEITMSPAIVIMQ
PILRFLQLLCENHNRELQNFLRNQNNKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINE
KNVALVNQTLESLTEYCQGPCHENQSCIATHESNGIDIIIALILNDINPLGKYRMDLVLQ
LKNNASKLLLAIMESRHDSENAERILFNMRPRELVDVMKNAYNQGLESDHEEESGDDGIS
PKDVGHNIYILAHQLARHNKILQQMLKPGSDSEEGDEALTYYANHTAQIEIVRHDRTMEQ
IVFPVPNICEFLTHESKYRVFNTTERDEQGSKVNDFFQQTEDLYNEMKWQKKIRNNPAIF
WFSRHISLWGSISFNLAVFINLAVALFYPFGDDGDEGTLSPLFSVLLWIAVAVCTSLLFF
FPKPVGIRPFLVSVMLRSIYTIGLGPTLILLGAANLCNKVVFLVSFVGNRGTFTRGYRAV
IMDMAFLYHVVYVLVCMLGLCVHEFFYSFLLFDLVYREETLLNVIKSVTRNGRSIILTAV
LALILVYLFSIVGFLFLKDDFIMEVERLKNRTPVADTGTVPTTTLTAMMETCEKDNCTTT
IPAIKSGEEDDEDGIERTCDTLLMCIVTVLNQGLRNGGGVGDVLRKPSKDEPLFAARVVY
DLLFYFIVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVSFE
EHIKSEHNMWHYLYFIVLVRVKDPTEYTGPESYVAQMIVEKNLDWFPRMRAMSLVSNEGD
SEQNEIRSLQERLESTMNLVKQLSGQLAELKEQMTEQRKNKQRLGFLGSNTPHVNHHMPP
H
NT seq 8106 nt   +upstreamnt  +downstreamnt
atgtctgacaaaatgtccagtttcctctacatcggggacatcgtttccctctacgccgag
ggctcggtcaacggcttcatcagcactttggggttggtggatgacagatgtgtggttcaa
ccagatgccggtgatctttgtaatcctcctaagaaattcagagactgcctctttaaagta
tgtcctatgaaccgatattctgcacagaagcagtactggaaatccaagcaggcaaaacaa
gggaatcacacggaagcagcactgctgaagaagctgcagcatgcagcggaactggagcaa
aaacagaatgaatgtgagaacaggaagctgcttggagaaattgtcaagtacagtaacgtc
atacagctgcttcacatcaaaagcaacaagtaccttactgtcaacaagagattgccagcc
ctgttggagaagaatgcgatgcgagtctccctggatgctgctgggaatgaggggtcatgg
ttttacatccaacccttttggaagctgaggagtgaaggtgacaatattgttgttggagac
aaagtggtcctcatgccggtcaatgcgggacagcctcttcatgccagcaacattgaactc
ctggacaacccaggatgcaaagaggtgaatgctgttaattgtaacacgagctggaaaata
accttatttatgaaatacagttgctacagagaggacgtgcttaaagggggggatgttgtc
agattgttccatgctgaacaagagaagtttcttacctgtgatgagtatcagaagcagcag
cacatctttcttcggacaacgttgcgtcagtcggctacttctgcaacaagttctaaagct
ctgtgggaaatcgaggtggtgcaccacgatccatgccgtggaggtgcgggacagtggaac
agcctcttcagatttaaacatctggcgactggaaactatttggctgcagaggtgagaatt
gcttctactgaatacagtaaagaatgctctagtagctatgacggcgaacttctcgcttca
aagaagaaacggcaggcaggggagaaaattatgtacactttggtgtctgtgccgcatgga
aatgatattgcctctctttttgagctggatgcaactacccttcagcgagctgactgctta
gttcccaggaattcatatgtccgactgagacacctttgcaccaatacatgggtaaccagt
accaacatcccaatagacaaagatgaagaaaggcctgtgatgttaaaaattggaacctgc
caaacaaaggaggacaaggaagcttttgctattgtgtctgtccctctgtctgaggtgaga
gatctggattttgccaacgatgccaacaaagttttagcatcttcagttaaaacgttggaa
aatggctcaatatcacaaaatgaacggagatttgctaccaagctcttagaggatctcatt
ttcttcattgctgatgtacccagtaatgttcaggaggttttggatgtagtagtcactaaa
cccaaccgggaaaggcaaaagttaatgagagaacaaaacatattagctcagatatttgga
atcctcaaagctccatttaaagataaagcaggagagggagccatgttgagactggaagat
ctgggcgatcaaagatatgcaccatacaaatacatactgaggctttgctatagactgctc
cggcattcccagcaggactaccggaaaaatcaggaatacattgcgaagaacttctgtatc
atgcagtcccagattggctatgatatcttggcagaagacacgatcacagctttgttgcac
aacaacaggaagctactagagaaacacatcacagctaaagaaatagagacatttgtgaat
ttactcaggaggaacagagagccaaggttcttggactatctatctgacttgtgtgtttcc
aacgcaacagccatcccagtaactcaggagctgatttgtaaatatatgctgaacccagga
aatgctgacattctcattcggaccaagttggtttcaatgcaagtggatggtcccatggaa
tgttctgccctttctgatgatattgacgaggaagaggtttggctgtactggatcgatagc
aataaggaaccacatggcaaagctatccgacatcttgctcaagaagcgaaagagggcaac
aagagtgatttagaagtccttacttattacaggtatcaattgaacctctttgcaaggatg
tgtttggaccgccagtatttggcaatcaaccagatttccatccagctctcagtagatctg
atcctacgctgcatgtcagatgagagcctgccttatgacctgcgagcatctttctgccgc
ctcatgttgcatatgcatgtggatagagatcctcaggagacagttgtgcctgtgaaatat
gcccggctgtggacggaaatccctactaagataaccatccacgagtatgactctttcacg
gattcatcaaggaatgacatgaagagaaaatttgctttgacaatggaatttgtagaagag
tacctgaaggaagttgtgaatcagccatttccttttggagacaaagataagaacaagcta
acttttgaggtggtgcacctggctcgcaatctcatatactttgggttttatagtttcagt
gagttgctgaggctgaccagaacactcttggctattcttgatattgtgcaaggccctatg
tcgtcctaccttgaaagattaagcaaatttcaggatggaggaaacaatgttatgaggacc
atccatggtgtaggagagatgatgacacaaatggtcctgagcagaggttccattttccct
ctcgctgcacctgaggttcctccaagtgtccacccaagcaaacaaatgggcactgtagag
agtgaagatattactgtgatggataccaagctaaaaatcattgagattttacagtttata
ctaagtgttcgacttgactacagaatatcctacatgctgtctatttacaagaaggagttt
ggagagagcagtgaaaccgttgatggttctgtagcgtctcctcctgagtcaccaattatc
acctcagctgttgttcctgacatagatgaaattgcagctcaagcagagactatgtttgct
ggcagaaaagaaaaaaatgcggtgcagctggatgatgaagggggcaggacttttttgcgc
gtcctcatccaccttattatgcacgactatccccctttgctgtcaggagccctgcacctc
ttgttcaaacatttcagccaacgagcagaagttttgcaagcatttaagcaggttcaattg
ctggtgtctaatcaggatgtggacaactacaagcaaataaaagctgatcttgaccagctg
aggctgacagtagaaaaatctgaactttgggttgataagaacagcagttatgagagtggt
gaactaggtgaaagtcaagccaaagggggcgatgagcccattgaggaatcaagtattctg
agtccagttcaggatgggagcaagaagcctcagattgacagcaataagagtaacaactac
aatattgttatggagattttgattcgcctaagtaaactctgtgtccagaataaaaagagt
cgaaatcagcagcaacgattgcttaaaaacatgggagcacactgtgtagtgttggatctt
ttacagataccctacgagaagacagatgagaagatgattgaagtgatgaacttggctcac
atgttccttcagaacttctgtcgtggaaaccctcagaatcaaatcctgcttcataaacat
atcaacttattcttaacacctggtctccttgaagccgaaaccatgcggcacatcttcaca
aacaactaccatctgtgcaatgaaattagtgagcgagcagtgcagcactttgtacactgc
attgagacacatggccgccacgtggagtatctccggttcctgcaaaccattgtgaaagca
gatggcaaatacgtcaagaagtgccaagatatggtaatgacagagctcgtgaatggaggt
gaagatgtgctagtgttttataatgacagagcctcctttccaatccttctccaaatgatg
tgctctgagagagaccgagtagatgagaatggggctttggcttaccacatcaccctggtg
gagttgctagcagcatgcacagaaggaaagaatgtgtatactgagatcaaatgtaattcc
ctcctgccgcttgatgacattgtgagagtggttactcatgaggactgcatacctgaggtc
aagattgcatatgtgaattttgtcaatcattgctacgtggacactgaggtggaaatgaag
gaaatctacactagtaaccacatctggaaattatttgaaaacttccttgttgatatggca
agggtctgtaacacaaccacagacagaaagcacgcggacacatctttggagaaatatgtc
tctgagcccgtcatgaacattgtgagtggctttttcagttctccgttttcagacaacacc
acaagcctccagactcatcagcctgtgtttattcagttgttgcagtcggcatttagaatt
tacaactgtacttggccaaacccaacacagaaatcttcggtggagtcttgtatcaaaact
ttggctgaagttgcaaagaaccgtggcattgccattccagtggatttggacagccaagtc
aatacattgttcatgaagagccataccaatatgatccagagagcagcgatgggctggcga
atgtctgctcgcagtggtcctcgtttcaaagaagccttgggaggacctgcctgggattat
aggaatatcattgagaagctacaggatgtggtaacttccttggaacagcagttcagtcca
atgatgcaagctgaattctcagtgttggttgatgttttgcgtagccctgagctgctcttt
cctgaggggagtgatgctcgaatcagatgtggagctttcatgtccaagttgataaatcac
acaaagaggctaatggagaaggaagaaaaactctgtatcaaaattctgcagactttacga
gaaatgctcgacgagaagaacagctttgcggaagagggcagcaacctgaggaagatactg
cttaatcgctattttaaaggtgatcatggaaacagcatcagtggtcctgtgtccagcagc
tatggcaaaactgcacaagggggaggtagcttttcaggacaagattcagataagtctggt
gtgtcgatgcatgatatccagtgccttctagataaagaaggagcatcggaacttgtcaca
gatgtcatagttagtaccaaaaatgacaggatattctcagaagccattttgcttggcatt
gctttgctggaaggtggaaacacacagattcagtattccttttatcatcaactgaatgag
caaaaaaaatctgagaagttttttaaagtcctgcatgatcgaatgaaaacagcacagcag
gaaatccgatcaacagtaacagtgaacactgttgatctggggaccaaaaagaaggatgag
gacaatgatgtgacagtctcgcttccaaaaaagagagtaagagactcaaatcttcacctg
aaagaaggaatgaaagggcaattaacagaagcttcaacagcaacctccaaagcttactgt
gtgtaccgcagagaaatggaccctgaaatagatctgataagttcaggaacagatgcagcg
aatgcagaagaaaagtcttctgaggaaataactatgagtcctgccattgtcatcatgcag
ccaatcctgaggttccttcagttgttgtgtgagaatcataatcgagaactccagaacttt
ttaagaaatcagaacaacaagaccaactacaacctcgtttgtgagacccttcagtttttg
gattgtatctgtggcagtacaacgggtgggctcggacttttgggtctgtacatcaatgag
aagaatgttgctctggtcaaccaaacgctggaaagcttgactgaatattgccaaggccca
tgccatgaaaaccagagctgtatagctacacatgaatctaatgggatagacattatcatt
gccttgatcctgaatgacatcaacccccttggaaaataccgcatggatctagtgcttcaa
ttgaagaataatgcctccaagcttttgctagctattatggaaagcaggcatgacagtgag
aatgcggaaagaatacttttcaacatgagaccaagagaactagtcgatgtaatgaagaat
gcatataatcagggtctggagagtgaccatgaggaagagagtggagacgatggtatttca
ccaaaagatgttggacataatatatatatcttggcacatcagctggcgcgtcacaacaaa
atattgcagcagatgttgaagcctgggtccgattcagaagaaggagatgaagccttgacg
tactatgccaatcacacggcccagattgagattgtccgtcatgatagaactatggaacaa
attgtcttccctgtgccgaacatttgtgaattccttacccacgaatccaagtatcgtgtg
ttcaatactactgagagagatgaacaaggaagcaaagtgaatgactttttccagcagaca
gaggacctgtataatgaaatgaagtggcagaagaaaatcagaaataatccagcaatcttt
tggttctcccgacacatttccctctggggaagtatttcgttcaatctggcagtttttatt
aatctagctgtagcacttttctacccctttggtgatgatggagatgaaggcactctttct
ccactgttttctgttctcctctggatagccgtggctgtgtgtacatccctgctgttcttc
ttccctaagcctgtgggcattcgtccctttctggtttccgtaatgctccggtcaatctat
acaattggccttggaccaacactgatccttctgggtgctgctaacctttgtaacaaggta
gttttcttagtgagctttgttgggaaccgtggcacattcactcgtggctaccgagcagtc
atcatggacatggcgttcctctaccacgtggtctacgtccttgtctgcatgttgggcctc
tgtgtacatgagttcttttacagcttcctgttatttgacttggtatacagagaggagacg
ttgctgaatgtcattaaaagtgttacacggaatggacgctccattatcctgactgctgtg
ctggccctcatccttgtttacctcttctccattgttgggttcttgttcttgaaagatgac
ttcattatggaagtggaaaggctgaaaaacaggacacctgtggcagacactggcacagtt
cccaccacaactttgacagcaatgatggaaacatgtgaaaaggataattgcactactaca
ataccagccataaaatcaggtgaggaagatgatgaggatgggattgagaggacatgtgac
actctgctaatgtgcattgtgacagtattgaaccaaggcctgagaaatggtggtggagtt
ggagatgtgttacgcaagccttccaaagatgagcccctcttcgctgcccgggttgtttat
gatctccttttctatttcattgtcatcattattgtcctgaacctcatctttggagtcatc
attgatacatttgctgatctgaggagtgaaaagcagaagaaagaggaaatcttaaaaaca
acctgcttcatctgtgggcttgagcgagacaaatttgataacaagacagtttcatttgag
gagcacatcaagtcagaacacaatatgtggcactacctttactttatagttctggtccgc
gtgaaagacccgacggaatacactggtcctgaaagttatgtggctcaaatgattgtggaa
aagaatttagactggttccctcggatgagagccatgtccctcgtcagcaacgagggcgac
agtgagcaaaatgaaattcggagcctgcaggagagactggagtccaccatgaacttggtc
aagcagttgtctggacaattagctgagctcaaagaacagatgacggaacaaaggaagaac
aagcagaggctgggctttctggggtctaacacgccccatgtgaaccatcacatgccgcca
cactga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (11)   
   KEGG PATHWAY (11)   
Genome (1)   
   KEGG GENOME (1)   
Gene (35)   
   KEGG ORTHOLOGY (1)   
   RefGene (31)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (8)   
   Pfam (8)   
All databases (59)   

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