KEGG   Galdieria sulphuraria: Gasu_03410
Entry
Gasu_03410        CDS       T02926                                 
Name
(RefSeq) thymidylate synthase/dihydrofolate reductase
  KO
K13998  dihydrofolate reductase / thymidylate synthase [EC:1.5.1.3 2.1.1.45]
Organism
gsl  Galdieria sulphuraria
Pathway
gsl00240  Pyrimidine metabolism
gsl00670  One carbon pool by folate
gsl00790  Folate biosynthesis
gsl01100  Metabolic pathways
gsl01232  Nucleotide metabolism
gsl01240  Biosynthesis of cofactors
Module
gsl_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:gsl00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    Gasu_03410
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    Gasu_03410
   00670 One carbon pool by folate
    Gasu_03410
Enzymes [BR:gsl01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     Gasu_03410
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.45  thymidylate synthase
     Gasu_03410
SSDB
Motif
Pfam: Thymidylat_synt DHFR_1
Other DBs
NCBI-GeneID: 17091137
NCBI-ProteinID: XP_005709089
UniProt: M2Y9L6
Position
Unknown
AA seq 503 aa
MGTMDCQCNIELRIVVALTRNARGIGLLGKMPWKLKKDLQFFKELTLGNPVIMGRKTWES
LPTASKPLKKRLNVVLTSNPTLFQKNYLETLTDEDRTEEEGLCLACNSLESALNMLRLRS
FPVAYIIGGRQVFEEALVNPACSRVYLTRIYEDFACDTFFPCLPNYFQLVSNSEIFEENG
IKFEFLEYRRDMYLTTGMNENSAHGKRQNINPSRPHEEYQYLELVRKIVEQGVFKNDRTG
VGTLSLFGHQMRFSLQGQFPLLTTKKVFWRGVVHELLWFISGSTNAKKLSEKGIHIWDEN
ASRAFLDNHGFLNREEGDLGPVYGFQWRHFGAKYRSMNDCYDNEGVDQLTDIIETLKRNP
NDRRMILTAWNPSAIPEMALPPCHILAQFYVSNDNLSCHMYQRSCDMGLGVPFNIGSYAL
LTYMIAKLVHLSPGELIYSMGDVHIYQNHLGPLTFQLNRKPRPFPRLIIKDRPDLQKIDD
FVFSDFELIDYHPHSVIKMPMAV
NT seq 1512 nt   +upstreamnt  +downstreamnt
atgggaactatggattgtcagtgtaacatagagttgaggattgttgtagctttaactaga
aatgcaagaggaattggattgcttgggaagatgccttggaaactaaagaaagatttgcag
tttttcaaagaactgacgttgggcaacccggttataatgggtcgtaaaacttgggagtct
ttgcctacagcgtcaaagcctttgaagaaaagattgaatgtcgtactgacaagtaaccct
accttatttcaaaaaaactacttggagacactgacggatgaagatcgcacagaggaagaa
gggttgtgcctagcgtgcaactcacttgagagtgcactaaacatgttaagactacgttct
tttcccgtggcatacattatcggaggtcgacaagtttttgaagaagccttagtgaatcct
gcttgtagccgcgtctatctgactagaatatacgaagacttcgcttgtgatacttttttc
ccttgtctccccaattattttcaactagtatcaaactccgaaatttttgaagagaatggt
atcaagtttgagtttttagaataccgaagagacatgtacctaacaacaggaatgaatgag
aatagtgcacatggcaaaaggcagaatattaacccatcgcgcccacatgaggaatatcaa
tacttggagcttgtcaggaagattgtggaacagggtgttttcaaaaatgaccgaacggga
gtcggtaccttatccttatttgggcatcagatgcgtttcagtctacagggtcagtttcct
ctccttacaacaaagaaggtattttggagaggagttgttcacgaacttttgtggtttatc
agtggctccacaaatgcaaagaaacttagtgagaagggtattcacatatgggacgagaat
gcttcccgtgcttttctagataatcatggttttttaaacagagaagaaggggatttagga
cctgtgtatggctttcaatggcgtcattttggagctaaatatagaagcatgaatgattgc
tatgacaatgagggagttgatcagttaaccgacatcatcgaaacactgaaacggaaccct
aatgatcgtcgtatgatattgacagcgtggaatccaagtgcaataccagaaatggcattg
cctccttgtcatatattggcacagttctacgtatctaatgacaatctttcctgtcatatg
taccagcgttcttgtgatatgggtctcggagtcccctttaacataggctcatacgcttta
ttaacctatatgattgcaaaacttgttcatttatcacctggtgaactcatttatagtatg
ggtgatgttcacatctatcaaaaccatctcggtccattgacctttcagctgaacagaaaa
ccacgaccttttccacgtctcataatcaaagaccgacctgacttgcaaaagattgatgac
tttgtgttttctgactttgagttgatagactatcatcctcattctgtgattaaaatgcca
atggcagtatag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (9)   
   KEGG PATHWAY (6)   
   KEGG MODULE (3)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (9)   
   KEGG ENZYME (2)   
   KEGG REACTION (7)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (2)   
   Pfam (2)   
All databases (41)   

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