KEGG   Geobacillus thermoleovorans CCB_US3_UF5: GTCCBUS3UF5_29860
Entry
GTCCBUS3UF5_29860 CDS       T01676                                 
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
gte  Geobacillus thermoleovorans CCB_US3_UF5
Pathway
gte00290  Valine, leucine and isoleucine biosynthesis
gte00620  Pyruvate metabolism
gte01100  Metabolic pathways
gte01110  Biosynthesis of secondary metabolites
gte01210  2-Oxocarboxylic acid metabolism
gte01230  Biosynthesis of amino acids
Module
gte_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:gte00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    GTCCBUS3UF5_29860
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    GTCCBUS3UF5_29860
Enzymes [BR:gte01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     GTCCBUS3UF5_29860
SSDB
Motif
Pfam: HMGL-like LeuA_dimer Radical_SAM
Other DBs
NCBI-ProteinID: AEV20289
UniProt: G8N467
Position
complement(2741592..2743139)
AA seq 515 aa
MRKIKFFDTTLRDGEQSAGVNLNLQEKLEIARQLERLRVDIIEAGFPASSKGDFEAVKQI
AETVRTCSVTGLSRSVRSDIDAAWEALKGGAEPRLHLFIATSPIHMVHKLRMTPEQVIEA
AVEAVKYAKRFFPIVQWSAEDACRSELPFLAKIVAEVIKAGASVINIPDTVGYITPKEYG
EIFLYLQNNVPNIEKVSLSAHCHDDLGMAVVNSLSAIEHGATQVECTINGIGERAGNAAL
EEIAVALHIRKDYYQVETRLNLQEIKRTSNLVSKLTGVVVPPNKAVVGKNAFAHESGIHQ
DGVLKEKTTYEIISPELVGVPSNSMVLGKHSGRHALRNRVEELGYTLSDEEINQLFVRFK
ELADKKKDITDDDLIALIFEEKFDHFKDFYQLSSIQVQYGTNQIPTAVVVLKDGKGNEIQ
EAATGAGSVEALYNTLERCFQTPVTLLDYRIESVGGGRDALAQVFVKVRAHDIETSGRGT
AQDVLEASAKAYINAINRVFMIEAMRGENEKVATP
NT seq 1548 nt   +upstreamnt  +downstreamnt
gtgcgaaaaattaagttttttgataccacattgcgtgatggggaacaatccgctggtgtg
aacttgaatttgcaagaaaagttggaaattgcccgtcaacttgaacggctgcgggttgac
atcatcgaggcgggtttccccgcctcatcgaaaggcgattttgaggcggtcaaacaaatt
gccgaaacggtgagaacatgctcggtcaccgggctgtcgcgctcggtccgaagcgacatt
gatgcggcgtgggaggcgttaaaaggcggcgcggagccgcggctccacctattcatcgcc
acctcgccgatccatatggtgcataaattgcggatgacgccggaacaagtgattgaagcg
gcggttgaggcggtgaaatacgcgaagcgctttttcccgatcgtccaatggtcggcggaa
gatgcgtgccgaagcgagttgccgtttttggcgaaaatcgtcgccgaagtgatcaaagcc
ggcgcctcggtgatcaacattccggatacggtcggctatattacgccgaaagaatacggg
gaaattttcctctatttgcaaaacaatgttccgaatattgaaaaggtttcactctccgct
cattgtcatgatgacttgggcatggcggtggtgaactcgctgtcggccattgaacatgga
gcgacgcaggtcgagtgcacgatcaacggcatcggcgagcgggccggcaatgcggcgctt
gaggaaatcgctgtcgcccttcacatccgcaaagactactatcaagtggaaacgcgcctc
aatttgcaggaaattaagcgcacaagcaatcttgtcagcaagctgaccggggtcgtcgtt
ccacccaacaaagcggtcgtcggcaaaaacgcgtttgcgcatgaatcgggcatccatcaa
gacggcgtcttaaaagaaaaaacgacatacgaaatcatttcgccggagctcgtcggcgtg
ccgtcgaattcgatggtgctcggcaaacattccggccgccatgcgcttcgcaaccgggtt
gaggagctcggctacacgttgtccgatgaagaaatcaatcagctgtttgtccgttttaaa
gaattggcggacaaaaagaaggacattaccgacgacgatttaatcgcgttgattttcgaa
gagaagttcgaccactttaaagatttttaccaattgtcttccattcaagtgcaatacggg
acgaatcaaattccgacagcggtagttgtactgaaagacgggaaggggaatgaaatccaa
gaagcggcgaccggcgccggcagcgtcgaggcgctgtacaatacattggaacgttgcttc
caaacgccggtgacgctgcttgactaccggatcgaatcggtcggcggcggccgcgatgcg
ttggcccaagtgttcgtcaaagtgcgcgcccatgacatcgagacgagcgggcgcggcact
gcacaagacgtgttggaagcatcggcgaaagcgtacatcaacgccatcaaccgtgtgttt
atgatcgaagcgatgcgcggcgaaaacgagaaagtggcaacaccataa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (3)   
   Pfam (3)   
All databases (24)   

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