KEGG T01344: HMPREF0421

Gardnerella vaginalis ATCC 14019: HMPREF0421_20400

Entry

HMPREF0421_20400  CDS       T01344

Name

(GenBank) putative dTDP-4-dehydrorhamnose reductase

K23987

dTDP-4-dehydrorhamnose 3,5-epimerase/reductase [EC:5.1.3.13 1.1.1.133]

Organism

gvg Gardnerella vaginalis ATCC 14019

Pathway

gvg00521

Streptomycin biosynthesis

gvg00523

Polyketide sugar unit biosynthesis

gvg00541

O-Antigen nucleotide sugar biosynthesis

gvg01100

Metabolic pathways

gvg01110

Biosynthesis of secondary metabolites

gvg01250

Biosynthesis of nucleotide sugars

Module

gvg_M00793

dTDP-L-rhamnose biosynthesis

Brite

KEGG Orthology (KO) [BR:gvg00001]
09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00541 O-Antigen nucleotide sugar biosynthesis
    HMPREF0421_20400
  09109 Metabolism of terpenoids and polyketides
   00523 Polyketide sugar unit biosynthesis
    HMPREF0421_20400
  09110 Biosynthesis of other secondary metabolites
   00521 Streptomycin biosynthesis
    HMPREF0421_20400
Enzymes [BR:gvg01000]
1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.133  dTDP-4-dehydrorhamnose reductase
     HMPREF0421_20400
5. Isomerases
  5.1  Racemases and epimerases
   5.1.3  Acting on carbohydrates and derivatives
    5.1.3.13  dTDP-4-dehydrorhamnose 3,5-epimerase
     HMPREF0421_20400

SSDB

Motif

Pfam:

RmlD_sub_bind dTDP_sugar_isom Epimerase GDP_Man_Dehyd NAD_binding_4 DUF6252 Polysacc_synt_2

Other DBs

NCBI-ProteinID:

ADP38482

UniProt:

E3D8T8

Position

complement(484720..486162)

AA seq 480 aa
MEFEKELSVTKTNIPGLIVFDLPVHGDNRGWFKENWQRAKMTALGLPDFGPVQNNISFNE
KRGVTRGIHAEPWDKYISIATGEVFGAWVDLRPGKSFGQVYTTTLNPSKAIYVPRGVGNS
FQALQDGTAYTYLVNAHWSLEQKKTYTFVNLADPDLHINWPIPLEESERSEADLHHPMLK
NAKPMAPKRTLVTGCNGQLGRAIQNYAKENNLEGFEYVDLDSFDIANKDDYSRYDWDLYG
TIINTAAYTSVDGAQTLQGRRAAWNSNVKGVANLAKIAQEHHITLVHISSDYVFDGTQEN
HKENEDFAPLGVYGETKAAADSLVANVPQHYIIRSSWIVGEGRNFVTRMIDFANRLKNGE
SVSVQAPIDQTGRLTFASDLVKGMFHLLNTQAQYGTYNLTGSGKIASWHDIAQKVFTQLN
VDTSKIEANRVDDYTRISNGSPRPHKCALDLQKIESAGFTPCDWEDLLESYVNRIEQNNK

NT seq 1443 nt +upstreamnt +downstreamnt
atggaatttgaaaaagaactaagcgttacaaaaaccaatattccaggtttaatcgtgttt
gatcttccagtacacggagataaccgcggatggttcaaagaaaactggcagcgcgcaaaa
atgacggctctaggtctccccgactttggacccgtacaaaacaacatttcgttcaacgaa
aaacgcggagtaaccagaggcatccacgcagagccatgggataaatacataagcattgct
actggcgaagtatttggcgcatgggtggatttaagaccaggtaaaagcttcggtcaagtg
tacacaaccacactaaaccctagcaaagcaatctacgttcctagaggcgtaggaaacagc
ttccaagctttgcaagatggcacggcatacacttatttagtaaacgcacattggtcacta
gagcaaaagaaaacatacacttttgtaaaccttgcagacccagatttacacattaattgg
ccaatacctttagaagaatccgagcgcagcgaagctgacttacaccacccaatgctaaaa
aacgcaaagccaatggcaccaaaacgcactcttgtaactggatgcaacggtcaacttggt
cgcgcaatacaaaattatgctaaagagaataatttagaaggatttgagtacgtagactta
gatagcttcgatatagcaaataaagacgattacagccgctacgactgggatttgtacgga
acgattattaacacagcagcatacacgtctgtagatggcgcgcaaacgctacaagggcga
agagccgcgtggaatagcaacgttaaaggagtggcaaatcttgcaaaaatagcgcaagaa
caccacattactcttgtgcacatctcaagcgactatgttttcgacggcactcaagaaaat
cacaaagaaaacgaagactttgcaccactaggcgtgtacggcgaaacaaaagctgcagca
gattctctagtagcaaacgttccacagcattatattattcgctcaagctggattgtcgga
gaaggacgaaactttgtaacgcgcatgattgactttgcaaaccgtttaaaaaatggcgaa
tctgttagtgttcaagcgccaatagatcaaactggcagactcacttttgcaagcgactta
gtaaaaggcatgttccatcttctaaacactcaagcacaatacggaacatacaatcttaca
ggttcaggaaaaatcgcgtcttggcacgatattgctcaaaaagtgtttacacaacttaat
gtagacacaagcaaaatcgaagcaaatcgcgtagacgattacacgcgcatatctaatggc
tctcctagaccacacaagtgcgcacttgacttacaaaaaatcgaatccgctggatttacg
ccatgcgattgggaagatttgcttgaatcttacgtaaatagaattgaacaaaacaacaag
taa

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