KEGG   Hahella sp. KA22: ENC22_13850
Entry
ENC22_13850       CDS       T05793                                 
Name
(GenBank) thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha
  KO
K00166  2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4]
Organism
hahe  Hahella sp. KA22
Pathway
hahe00280  Valine, leucine and isoleucine degradation
hahe00640  Propanoate metabolism
hahe00785  Lipoic acid metabolism
hahe01100  Metabolic pathways
hahe01110  Biosynthesis of secondary metabolites
hahe01210  2-Oxocarboxylic acid metabolism
Module
hahe_M00036  Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:hahe00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00640 Propanoate metabolism
    ENC22_13850
  09105 Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    ENC22_13850
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    ENC22_13850
Enzymes [BR:hahe01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.4  3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
     ENC22_13850
SSDB
Motif
Pfam: E1_dh DXP_synthase_N GIT_SHD
Other DBs
NCBI-ProteinID: AZZ92221
UniProt: A0A3T0VM64
Position
3108814..3110001
AA seq 395 aa
MSQTTKTIEVIHKPEFIQGNEFKFPIFQVLKQDGATYKGAKLPEMDQEEALKIYRTMVFT
RVLDERMLAAQRQGRLSFYLQSTGEEGTVVGFAAALDDRDMIMAQYREQGALAYRGFSVD
EFMNQLFGNELDYGKGRQMPIHYGSAKLNYMTISSPLATQIPQAAGYAYGQKLEGKGLCT
VTVFGEGAASEGDFHAALNMASVHKVPVIFLCRNNGYAISTPSSEQFAADGIAPRALGYS
MRAIRVDGNDILAVYLATQAARKIAVEENEPVLIEAMTYRLAAHSSSDDPSGYRSKKEED
VWRAKDPIARMRNWMIKKKWWSEDEEKQLQDSMRQEVLDAMKNAEKRPPPPVESLVTDVY
DEVTPQLHEQLEKLKMHVRKYPDAYPKSAGRMTHG
NT seq 1188 nt   +upstreamnt  +downstreamnt
atgagtcaaacaacaaaaacaatagaagttattcataaacctgaattcattcagggaaat
gaatttaagtttcccatctttcaggttctgaaacaggatggcgcgacctataaaggggct
aagctgccggagatggatcaggaagaagccctgaagatctaccgcaccatggtgttcacc
cgcgtgctggatgaacgcatgctggccgcccagcgtcaggggcgtctcagtttttacctg
cagtccaccggtgaagaaggcactgttgtcggcttcgctgcggcgttggatgatcgggac
atgatcatggctcaataccgggagcagggcgctttggcctatcgcggattctcggtggat
gagttcatgaaccagctgttcggcaacgagctggattatggcaagggccggcaaatgccg
attcactacggctccgccaaactcaattacatgacgatttcctcgcctctggccacccag
attcctcaggccgccggttacgcctacggtcagaaactggaaggcaaggggctttgcacc
gtaaccgtattcggcgaaggcgccgcctcggaaggggactttcacgccgcgctgaacatg
gcctccgtgcataaagtgccggttatttttctatgccgtaacaacggctacgcgatctcc
actccttccagcgaacagttcgccgcagacggcattgcgccgcgggcgttaggttacagc
atgcgcgccatccgcgtagacggcaacgatatcctggcggtgtatctggcgacccaggcc
gcgcgcaaaattgcagtggaagaaaacgaacctgttttgatcgaagccatgacctaccgt
ctggccgcccactcctcctccgacgacccatccggctaccgcagcaagaaagaagaagac
gtttggcgcgccaaagaccccattgcgcgcatgcgcaactggatgatcaagaaaaagtgg
tggtccgaggacgaagaaaagcagcttcaggacagcatgcgccaggaagtgctggacgca
atgaagaacgctgagaaacggccgccgccgccggtggagtcgctggtgacggacgtgtac
gacgaagtgaccccgcaactgcatgaacaattagaaaaactcaagatgcatgtccgcaag
tacccggatgcgtatcccaagagcgcggggagaatgacgcatggctaa

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