KEGG   Hipposideros armiger (great roundleaf bat): 109380439
Entry
109380439         CDS       T04661                                 
Symbol
CACNA1S
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1S
  KO
K04857  voltage-dependent calcium channel L type alpha-1S
Organism
hai  Hipposideros armiger (great roundleaf bat)
Pathway
hai04010  MAPK signaling pathway
hai04020  Calcium signaling pathway
hai04022  cGMP-PKG signaling pathway
hai04024  cAMP signaling pathway
hai04260  Cardiac muscle contraction
hai04261  Adrenergic signaling in cardiomyocytes
hai04270  Vascular smooth muscle contraction
hai04723  Retrograde endocannabinoid signaling
hai04725  Cholinergic synapse
hai04726  Serotonergic synapse
hai04727  GABAergic synapse
hai04911  Insulin secretion
hai04912  GnRH signaling pathway
hai04921  Oxytocin signaling pathway
hai04924  Renin secretion
hai04925  Aldosterone synthesis and secretion
hai04927  Cortisol synthesis and secretion
hai04929  GnRH secretion
hai04934  Cushing syndrome
hai04935  Growth hormone synthesis, secretion and action
hai05010  Alzheimer disease
hai05020  Prion disease
hai05022  Pathways of neurodegeneration - multiple diseases
hai05207  Chemical carcinogenesis - receptor activation
hai05410  Hypertrophic cardiomyopathy
hai05412  Arrhythmogenic right ventricular cardiomyopathy
hai05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:hai00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    109380439 (CACNA1S)
   04020 Calcium signaling pathway
    109380439 (CACNA1S)
   04024 cAMP signaling pathway
    109380439 (CACNA1S)
   04022 cGMP-PKG signaling pathway
    109380439 (CACNA1S)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    109380439 (CACNA1S)
   04929 GnRH secretion
    109380439 (CACNA1S)
   04912 GnRH signaling pathway
    109380439 (CACNA1S)
   04921 Oxytocin signaling pathway
    109380439 (CACNA1S)
   04935 Growth hormone synthesis, secretion and action
    109380439 (CACNA1S)
   04924 Renin secretion
    109380439 (CACNA1S)
   04925 Aldosterone synthesis and secretion
    109380439 (CACNA1S)
   04927 Cortisol synthesis and secretion
    109380439 (CACNA1S)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    109380439 (CACNA1S)
   04261 Adrenergic signaling in cardiomyocytes
    109380439 (CACNA1S)
   04270 Vascular smooth muscle contraction
    109380439 (CACNA1S)
  09156 Nervous system
   04727 GABAergic synapse
    109380439 (CACNA1S)
   04725 Cholinergic synapse
    109380439 (CACNA1S)
   04726 Serotonergic synapse
    109380439 (CACNA1S)
   04723 Retrograde endocannabinoid signaling
    109380439 (CACNA1S)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    109380439 (CACNA1S)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    109380439 (CACNA1S)
   05020 Prion disease
    109380439 (CACNA1S)
   05022 Pathways of neurodegeneration - multiple diseases
    109380439 (CACNA1S)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    109380439 (CACNA1S)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    109380439 (CACNA1S)
   05414 Dilated cardiomyopathy
    109380439 (CACNA1S)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    109380439 (CACNA1S)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:hai04040]
    109380439 (CACNA1S)
Ion channels [BR:hai04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   109380439 (CACNA1S)
SSDB
Motif
Pfam: Ion_trans Ca_chan_IQ GPHH PKD_channel CAC1F_C
Other DBs
NCBI-GeneID: 109380439
NCBI-ProteinID: XP_019493541
EnsemblRapid: ENSHARG00000003992
UniProt: A0A8B7QXX5
Position
Unknown
AA seq 1807 aa
MEPSSPQDEGLRKKQPKKPVPESLPRPPRALLCLTLQNPLRKACISIVEWKYPLGPGRRG
QRRVTNDNCTNRLPPQEKLEYFFLIVFSVEAAMKIIAYGFLFHQDAYLRSGWNVLDFIIV
FLGVFTVILEQVNVIQSNTAPMSHKGAGLDVKALRAFRVLRPLRLVSGVPSLQVVLNSIF
KAMLPLFHIGLLVLFMVTIYAIIGLELFKGKMHKTCYFVGTDIVATVDNEKPSPCARTGS
GRPCTINGSECRGGWPGPNHGVTHFDNFGFSMLTVYQCITMEGWTDVLYWVNDAIGNEWP
WIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLDEDLRGYMSWV
TQGEVMDAEDLREGKLALDEGGSDTESLYEIEGLNKIIQFIRHWRQWNRIFRWKCHDVVK
TRAFYWLVILIVALNTLSIASEHHNQPLWLTHLQDVANQVLLCLFTIEMLMKMYGLGLRQ
YFMSIFNRFDCFVVCSGLLEILLVASGAMSPLGISVLRCIRLLRLFKVTKYWTSLSNLVA
SLLNSIRSIASLLLLLFLFIIIFALLGMQLFGGRYDFEDTEVPRSNFDNFPQALISVFQV
LTGEDWNSVMYNGIMAYGGPSYPGMLVCIYFIILFVCGNYILLNVFLAIAVDNLAEAESL
TSAQKAKAEERKRRKMSRGLPEKSEEEKSMATKKLEQKPKGEGIPTTAKLKVDEFESNVN
EVKDPYPSADFPGDDEEDEPEIPVSPRPRPLAELQLKEKAVPIPEASSFFIFSPTNKIRV
MCHRIVNATWFTNFILLFIMLSSAALAAEDPIQAESMRNQILGYFDIGFTSVFTVEIVLK
MTTYGAFLHKGSFCRNYFNILDLLVVAVSLISMGLPSSSISVVKILRVLRVLRPLRAINR
AKGLKRGYYYVYKDEDPTQMQLYPREWVHNDFHFDNVLSAMMSLFTVSTFEGWPQLLYRA
IDSNEEDKGPVYNNRVEMAIFFIVYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCELDK
NQRQCVQYALKARPLRCYIPKNPYQYQVWYLVTSSYFEYLMFALIMLNTICLGMQHYNQS
EQMNHISDILNVAFTIIFTLEMVLKLMAFKARGYFGDPWNVFDFLIVIGSIIDVILSEID
TFLASSGGLYCLGGGCGTVDPDESARISSAFFRLFRVMRLIKLLNRAEGVRTLLWTFIKS
FQALPYVALLIAMLFFIYAVIGMQMFGKIALVDGTQINRNNNFQTFPQAVLLLFRCATGE
AWQEILLACSPGKLCDPASDYAPGEEYSCGTNFAYYYFISFYMLCAFLIINLFVAVIMDN
FDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCPHRV
ACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGNFEQANEELRAIIKKIWKRTSM
KLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKFMKRQEEYYGYRPKKDAVQIQAGLRTIE
EEAAPEIRRTISGDLTAEEELERAMVEAAMEEGIFRRTGGLFGQVDSFLERTNSLAPVMA
NQRPLQFAEIEMEELESPVFLEDFPQDPGTNPLARANTNNANANVARGNCSHSDSPAFSS
VHYEREPAGETDTPAARGGALGLSFLGTQEGPLSTSCAEKRKGQLAQRLVPTAPAPPAPC
QPPVPEVRRRPTPGSLPEQTPHSSRTQEGPSRCPASATALLIQEALVRGGLDTLAADAGF
VMATGHALADACRMEPEEVEVAATELLRGRESLQGTASPLGSLSLRSSLGSLDQRQGSQE
TLIPPRP
NT seq 5424 nt   +upstreamnt  +downstreamnt
atggagccgtcctccccgcaggacgagggcctgaggaagaagcagcccaagaagcctgtg
cctgagagtttgccgaggccgccgcgagccttgctgtgtttgaccctccagaacccgctg
aggaaagcctgcatcagcattgtggaatggaagtatcctctgggcccagggcggcgggga
caaaggagagtgaccaatgataactgcacgaaccgcttgcccccgcaggagaagctggag
tacttcttcctcatcgtcttctccgttgaagccgccatgaagatcatcgcctacggcttc
ctcttccaccaggacgcctacctgcgcagcggctggaacgtgctggacttcatcatcgtc
ttcctgggggtcttcacagtgattctggagcaggttaacgtcatccaaagcaacaccgct
ccgatgagccacaaaggagctggcctggacgtgaaggcactgagagccttccgcgtgctc
agacccctccggctggtgtcgggggtgcccagcctgcaggtggtcctcaactccatcttc
aaggccatgctcccgctgttccacatcggcctgctggtcctcttcatggtcaccatctac
gccatcatcgggctggagctcttcaagggcaagatgcacaagacctgctacttcgttgga
actgacatcgtggccaccgtggacaacgagaagccgtccccctgcgccaggacgggctcg
ggccgcccgtgcaccatcaacggcagcgagtgccggggcggctggccggggcccaaccac
ggcgtcacccactttgacaacttcggcttctccatgctgaccgtgtaccagtgcatcact
atggaaggctggaccgacgtgctctactgggtcaacgatgccattgggaacgagtggccc
tggatctattttgtcaccctcattctgctgggatccttcttcatcctcaacctggtgctg
ggtgtcctgagcggggagttcaccaaggagcgggagaaggccaagtccagggggaccttc
cagaagctccgcgagaagcagcagctggacgaggacctccggggctacatgagctgggtc
acccagggagaggtcatggatgctgaggacctgagagaaggaaagctggccttggatgaa
ggtggctccgacacagagagcctgtatgagattgagggattgaacaaaatcatccagttc
atccgacactggaggcagtggaaccgtatctttcgctggaagtgccacgacgtggtgaag
accagagccttctactggctggtgatcctgattgtggccctcaacaccctgtccatcgcc
tctgagcaccacaaccagccgctctggctgacccatctgcaagatgttgccaaccaggtg
ctgctgtgcctcttcaccatcgagatgctgatgaagatgtacgggctgggcctgcggcaa
tacttcatgtccatcttcaaccgcttcgactgcttcgtggtgtgcagcggcctcctggag
atcctgcttgtggcctcgggcgccatgagccccctgggcatctccgtgctgcgctgcatt
cgcctcctcaggctcttcaaggtcaccaagtactggacgtcgctgagcaacctggtggcg
tccctgctcaactccatccgctccatcgcctcgctgctgctgctgctgttcctcttcatc
atcatcttcgccctgctgggcatgcagctcttcgggggcaggtacgacttcgaggacacc
gaggtgcctcgcagcaacttcgacaacttcccgcaggctctcatcagcgtcttccaggtc
ctgacaggtgaagactggaactccgtgatgtacaacggcatcatggcctacggggggccc
tcctaccccgggatgcttgtgtgcatctacttcatcatcctgttcgtctgcggcaactac
atcctgctcaacgtcttcctggccattgccgtggacaacctggccgaggcggagagcctg
acctctgcccagaaggccaaggctgaggagaggaaacgccggaagatgtccaggggtctc
ccagagaagtctgaggaggagaagtcaatggcgaccaagaagctggagcagaagcccaag
ggggagggtatccccaccaccgccaagctgaaagtcgatgagtttgagtctaacgtcaat
gaggtgaaggacccctacccctcggctgactttccaggagacgatgaagaagatgagccc
gagatcccagtgagcccccgaccgcggcccctggctgagctgcagctgaaagagaaggcc
gtgcccatcccagaagccagttccttcttcatcttcagccccaccaacaagatccgcgtc
atgtgtcatcgcatcgtaaacgccacctggttcaccaacttcatcctgctcttcatcatg
ctcagcagtgctgcgctggccgccgaggaccccatccaggccgagtccatgaggaaccag
atcctcgggtattttgacattggattcacctctgtcttcactgtggagattgtcctcaag
atgaccacctatggtgccttcctgcacaaaggctccttctgccgcaactacttcaacatc
ctggacctgctggtggtggccgtgtcactcatctccatgggactcccgtccagctccatc
tcagtggtgaagatcctgagggtgctgagggtgctccgaccgctgcgagccatcaacaga
gccaaagggctgaagaggggctattactacgtgtacaaggatgaggaccccacgcagatg
cagctgtacccccgcgagtgggtgcacaacgacttccacttcgacaacgtgctgtcggcc
atgatgtccctcttcaccgtgtccaccttcgaggggtggccgcagctgctgtacagggcc
atcgactcaaacgaggaggacaagggccccgtgtacaacaaccgcgtggagatggccatc
ttcttcatcgtctacatcatcctcatcgctttcttcatgatgaacatcttcgtgggcttt
gtcatcgtcaccttccaggagcagggggagaccgagtacaagaactgcgagctggacaag
aaccagcgccagtgtgtgcagtacgcgctgaaggcccgccccctgaggtgctacatcccc
aagaacccataccagtaccaggtatggtacttggtcacctcttcctactttgagtacctg
atgtttgctctcatcatgctcaacaccatctgcctgggcatgcagcactacaaccagtcc
gagcagatgaaccacatctcagacatcctcaacgtggccttcaccatcatcttcaccctg
gagatggtcctcaagctcatggcgttcaaggcccgaggctattttggggacccctggaat
gtgtttgacttcctgattgtcattggcagcatcattgatgtcatcctcagcgagatcgac
actttcctggcctccagtgggggactgtattgcctgggtggaggctgcgggaccgttgac
ccagacgaaagcgcccgcatctccagcgccttcttccgcctgttccgggtcatgaggctg
atcaagctgctgaaccgggcagagggggtgcgaaccctgctgtggactttcatcaagtcc
ttccaggccctgccctacgtggctctgctcatcgccatgctgttcttcatctacgccgtc
atcggcatgcagatgtttggaaagatcgccttggtggacgggacccaaataaaccggaac
aacaacttccagaccttcccgcaggctgtgctgctgctcttcaggtgtgcgacaggtgag
gcgtggcaggagatcctgctggcctgcagccctggcaagctgtgcgaccccgcgtcggac
tacgcgcccggcgaggagtactcgtgcggcaccaacttcgcctactactatttcatcagc
ttctacatgctctgtgccttcctgatcatcaacctctttgtggccgtcatcatggacaac
ttcgactacctcacgcgggactggtccatcctgggccctcatcacctggatgagttcaag
gccatctgggcagagtacgacccggaggcgaagggcagaatcaaacacttggacgtggtg
accctgctgagaaggattcagccccctctgggctttgggaagttctgtccgcaccgggtg
gcatgtaagcgactcgtgggcatgaacatgcccctgaacagtgacggaacggtcaccttc
aatgccacactcttcgccctagtccgcacggccctgaagatcaagacagaaggtaacttc
gagcaggcgaatgaggagctgagggccatcatcaagaagatctggaagagaaccagtatg
aagctcctggatcaggtcatccctcccataggagatgacgaggtgactgtggggaagttc
tacgccacgttcctcatccaggaacacttccggaagttcatgaaacgccaggaggagtat
tacgggtatcggcccaagaaggacgccgtgcagatccaggccggactgcggaccatcgag
gaggaggctgcccctgagatccgccggaccatctcaggagacctgacggctgaagaggag
ctggagagagccatggtggaggccgcgatggaagaagggatattccggaggacaggaggc
ctgtttggccaggtggacagcttcctggaaaggaccaactccctggcccccgtcatggcc
aaccagagacccctccagtttgccgagatagagatggaggagctggagtcgcccgtcttc
ttggaggacttccctcaggacccgggaaccaacccccttgctcgtgccaataccaacaac
gccaacgccaacgttgcccgtggcaactgcagccatagtgacagcccggcgttttccagc
gtccactatgaaagggagcctgctggggagacagacacccccgcagccagaggaggagcc
ctgggtctgtcttttctgggcacccaagaaggacccctcagcacatcctgtgcggaaaag
cggaaaggacagctggcccagagattggtgcccacagccccggcccctcctgccccctgc
cagcccccagtgcctgaggtgaggaggcgccccacaccagggtctctgcctgagcaaacc
ccccacagcagtaggacccaggagggtccgtccagatgcccggcttcagctacggccctg
ctgatccaagaggctctggttcgaggtggcctggacactttggcggcggatgctggcttt
gtcatggcaacgggccatgccctggcagacgcctgccggatggaaccagaggaagtggag
gtggcagcaactgagctgctgagaggacgggaatccctgcagggcacggccagtcccctg
ggctccctgagcctcaggtcctccctgggcagcctcgaccagcgtcagggctcccaggag
accctcattccccccaggccgtga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (27)   
   KEGG PATHWAY (27)   
Genome (1)   
   KEGG GENOME (1)   
Gene (40)   
   KEGG ORTHOLOGY (1)   
   RefGene (35)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   ENSEMBLRAPID (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (5)   
   Pfam (5)   
All databases (78)   

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