KEGG   Hipposideros armiger (great roundleaf bat): 109387530
Entry
109387530         CDS       T04661                                 
Symbol
PTEN
Name
(RefSeq) phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1
  KO
K01110  phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
Organism
hai  Hipposideros armiger (great roundleaf bat)
Pathway
hai00562  Inositol phosphate metabolism
hai01100  Metabolic pathways
hai01521  EGFR tyrosine kinase inhibitor resistance
hai04068  FoxO signaling pathway
hai04070  Phosphatidylinositol signaling system
hai04071  Sphingolipid signaling pathway
hai04115  p53 signaling pathway
hai04140  Autophagy - animal
hai04150  mTOR signaling pathway
hai04151  PI3K-Akt signaling pathway
hai04218  Cellular senescence
hai04510  Focal adhesion
hai04931  Insulin resistance
hai05165  Human papillomavirus infection
hai05166  Human T-cell leukemia virus 1 infection
hai05200  Pathways in cancer
hai05206  MicroRNAs in cancer
hai05208  Chemical carcinogenesis - reactive oxygen species
hai05213  Endometrial cancer
hai05214  Glioma
hai05215  Prostate cancer
hai05218  Melanoma
hai05222  Small cell lung cancer
hai05224  Breast cancer
hai05225  Hepatocellular carcinoma
hai05230  Central carbon metabolism in cancer
hai05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
hai05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:hai00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    109387530 (PTEN)
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    109387530 (PTEN)
   04070 Phosphatidylinositol signaling system
    109387530 (PTEN)
   04071 Sphingolipid signaling pathway
    109387530 (PTEN)
   04151 PI3K-Akt signaling pathway
    109387530 (PTEN)
   04150 mTOR signaling pathway
    109387530 (PTEN)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    109387530 (PTEN)
  09143 Cell growth and death
   04115 p53 signaling pathway
    109387530 (PTEN)
   04218 Cellular senescence
    109387530 (PTEN)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    109387530 (PTEN)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    109387530 (PTEN)
   05206 MicroRNAs in cancer
    109387530 (PTEN)
   05208 Chemical carcinogenesis - reactive oxygen species
    109387530 (PTEN)
   05230 Central carbon metabolism in cancer
    109387530 (PTEN)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    109387530 (PTEN)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    109387530 (PTEN)
   05214 Glioma
    109387530 (PTEN)
   05218 Melanoma
    109387530 (PTEN)
   05215 Prostate cancer
    109387530 (PTEN)
   05213 Endometrial cancer
    109387530 (PTEN)
   05224 Breast cancer
    109387530 (PTEN)
   05222 Small cell lung cancer
    109387530 (PTEN)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    109387530 (PTEN)
   05165 Human papillomavirus infection
    109387530 (PTEN)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    109387530 (PTEN)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    109387530 (PTEN)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    109387530 (PTEN)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hai01009]
    109387530 (PTEN)
Enzymes [BR:hai01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     109387530 (PTEN)
    3.1.3.48  protein-tyrosine-phosphatase
     109387530 (PTEN)
    3.1.3.67  phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase
     109387530 (PTEN)
Protein phosphatases and associated proteins [BR:hai01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Dual specificity phosphatases)
   Phosphatase and Tensin homologs (PTEN)
    109387530 (PTEN)
SSDB
Motif
Pfam: PTEN_C2 DSPc Y_phosphatase PTPlike_phytase Y_phosphatase3 DUF3256
Other DBs
NCBI-GeneID: 109387530
NCBI-ProteinID: XP_019507041
UniProt: A0A8B7S124
Position
Unknown
AA seq 388 aa
MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRCAERH
YDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMI
CAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLLKNHLDYRPVALLF
HKMMFETIPMFSGGTCNPHFVVCQLKVKIYSSNSGPTRREDKFMYFEFPQPLPVCGDIKV
EFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEIDSICSIERAENDKEY
LVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEASSSTSVTPDVSDNEPD
HYRYSDTTDSDPENEPFDEDQHTQITKV
NT seq 1167 nt   +upstreamnt  +downstreamnt
atgacagccatcatcaaagagatcgttagcagaaacaaaaggagatatcaagaggatgga
ttcgacttagacttgacctatatttatccaaacattattgcaatggggtttcctgcagaa
agacttgaaggtgtatacaggaacaatattgatgatgtagtaagatgtgctgaaagacat
tatgatactgccaaatttaactgcagagttgcacagtatccttttgaagaccataatcca
ccacagctagaacttatcaaacccttttgtgaagatcttgaccaatggctaagtgaagat
gacaatcatgttgcagcaattcactgtaaagctggaaagggacgaactggtgtaatgatt
tgtgcatatttgttacatcggggcaaatttttaaaggcacaagaggccctagatttctat
ggggaagtaaggaccagagacaaaaagggagtaactattcccagccagaggcgctatgtg
tattattatagctacctgttaaagaatcatctggattatagaccagtggcactgttgttt
cacaagatgatgtttgaaacaattccaatgttcagtggcggaacttgcaatcctcatttt
gtggtctgccagctaaaggtgaagatatattcctccaattcaggacccacacgacgagaa
gacaagttcatgtactttgagttccctcagccgttgcctgtgtgtggtgacatcaaagta
gagttcttccacaaacagaacaagatgctaaaaaaggacaaaatgtttcatttttgggtg
aatacattcttcataccaggaccagaggaaacctcagaaaaagtagaaaatggaagtcta
tgtgatcaagaaattgatagtatttgcagtatagagcgtgcagaaaacgacaaggaatat
ctagtactcactttaacaaaaaatgatctcgacaaagcaaataaagacaaagccaatcga
tacttttctccaaattttaaggtaaagctgtacttcacaaaaacagtagaggagccatca
aatccagaagctagcagctccacttctgtaacaccagatgttagtgacaatgaacccgat
cattatagatattctgacaccactgactctgatccagagaatgaaccttttgatgaagat
cagcatacacaaattacaaaagtctga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (28)   
   KEGG PATHWAY (28)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (5)   
   KEGG ENZYME (3)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (8)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (6)   
   Pfam (6)   
All databases (62)   

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