KEGG   Candidatus Hamiltonella defensa (Acyrthosiphon pisum): HDEF_1208
Entry
HDEF_1208         CDS       T00911                                 
Symbol
putA
Name
(GenBank) multifunctional: transcriptional repressor of proline utilization; proline dehydrogenase; pyrroline-5-carboxylate dehydrogenase
  KO
K13821  RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88]
Organism
hde  Candidatus Hamiltonella defensa (Acyrthosiphon pisum)
Pathway
hde00250  Alanine, aspartate and glutamate metabolism
hde00330  Arginine and proline metabolism
hde01100  Metabolic pathways
hde01110  Biosynthesis of secondary metabolites
Module
hde_M00970  Proline degradation, proline => glutamate
Brite
KEGG Orthology (KO) [BR:hde00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    HDEF_1208 (putA)
   00330 Arginine and proline metabolism
    HDEF_1208 (putA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hde03000]
    HDEF_1208 (putA)
Enzymes [BR:hde01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.88  L-glutamate gamma-semialdehyde dehydrogenase
     HDEF_1208 (putA)
  1.5  Acting on the CH-NH group of donors
   1.5.5  With a quinone or similar compound as acceptor
    1.5.5.2  proline dehydrogenase
     HDEF_1208 (putA)
Transcription factors [BR:hde03000]
 Prokaryotic type
  Ribbon-helix-helix
   Other families
    HDEF_1208 (putA)
SSDB
Motif
Pfam: Aldedh Pro_dh Pro_dh-DNA_bdg PRODH HicB_lk_antitox
Other DBs
NCBI-ProteinID: ACQ67867
UniProt: C4K5M4
Position
complement(1121556..1125380)
AA seq 1274 aa
MHKNISDIESTEPIHAPFSYFYDPLYTPSDLQTAMNLAYRRPESDAIREWLEDARLTPDL
AQATQNLAYRLCKNLRENKNDRLFSGIVQNLLQEFSLSSREGIALMCLAEALLRIPDKKT
RDLLIRDKITQGEWGDHLGRSRSIFVNASAWGLLLSRRFVRQYSVSSELTLKNALSRVIK
KSGEPVIRKALNVSIRLMGEQFVTGETIEKALKKSKKYENKGFLYSYDMLGEAALTEEDA
KAYWMTYHNAIDVIGAASKHRGVYESPGISIKLSALHPRYTRSQYKVLVEELYPRLLSLA
QKARRYNIGINIDAEETERLPISLSFLEKLCFEPDLKGWSGIGFVIQSYQKRCPFVIDAL
IDLAKRSEHRLMIRLVKGAYWDREIKHAQVEGLSDYPVYTRKPHTDISYLACARKLLAFP
ELIYPQFATHNAYTLASIYYLAGGENYAPEQYEFQCLNGMGEPLYQHVVGAVSEGGLNRP
CRIYAPVGSHKTLLAYLVRRLLENGANTSFVNRIADLNIPLEQLIQDPVEWVEKKAASEG
TLGLMNPMIPLPRDLYHDTFCDKKRANACGVDLSDEQVLASISEGLFASAKKVKSAYPII
GLEPGKGGVEKKIFNPANTEDLVGYVREATSSEAIRALHFACTTQAEWAETPPAERAGFL
LKAADAMESEKGSLLELLIRETGKTLENAINEIREAVDFLRYYAVIVEQHFSNKTEIPLG
PVVCISPWNFPLAIFTGQVAAALASGNCVLAKPAEQTPLIATEVVRILFEAGVPRKALQL
LPGAGESIGSLLVKDPRVAGVMFTGSTSVARLIQNHLSERLNKKNHPIPFIAETGGLNAM
IVDSSALTEQVVTDVMKSAFDSAGQRCSGLRILCLQEDIAHKTLHMLRGAMAAYRVGNPE
HFSTDIGPVIDARAKEMIEGHIQAMKEKGRTVYQAAHLNKLDKNTDSKGYFIKPTLIELD
TFDELQKEIFGPVLHVVRFKRTDLMTMVDKINATGYGLTLGIQSRIDETISEITARAKVG
NIYVNRNMVGAVVGVQPFGGEGLSGTGPKAGGPLYLYRLLASRSNKALNQTLLQQTKEQI
SDVDQDKTRLNAQEAFKEWLREQDKSELLELAQEYMKYTVSGQAFLLSGPTGESNTYQLC
PREKVLCLADDEKDAYIQLTAVLVVGSQVIWPKKNLQTQFFASLPPLVQQRISFADNNDW
SSDSLFFDAVIHHGDHETLTVLCQQLAKRSGPIVSVQGLYQGDPQIQLERLVIERSLSIN
TTAAGGNTYLMTMS
NT seq 3825 nt   +upstreamnt  +downstreamnt
atgcataaaaatatcagcgatatcgaatctacagagcctattcacgcgcctttttcttat
ttttacgatccgctttacacaccatccgatttacaaacagccatgaatctggcttatcgt
cgtccagaatctgacgcaattcgtgagtggcttgaagatgcgcgattgacgcctgatttg
gctcaagcaacccaaaatttggcctataggctttgtaaaaatttacgtgaaaacaaaaat
gaccgtcttttttcaggcatcgtccaaaatttattacaggaattttctttatcgtctcga
gaaggcatcgcactgatgtgtttggcagaggccctattgcggatccctgataaaaaaact
cgcgatctgctgatcagagataaaatcactcaaggggagtggggagatcatttgggtcgt
agccgttctatttttgtgaatgcaagtgcttggggtttattactgagccgtcgtttcgtc
agacaatattctgtctcatcagagctcacccttaaaaatgcgctcagtcgtgtgattaaa
aaaagcggggagcctgtgattcgtaaagcattaaatgtgtccatccgtttgatgggagaa
cagtttgtcacgggtgaaaccatcgaaaaagcgctgaaaaaatccaaaaaatatgaaaat
aaaggatttctctattcgtatgacatgttgggggaagccgcgctcacagaagaagatgcc
aaggcttattggatgacctatcacaacgccattgatgtcataggcgccgcttctaagcac
aggggagtttatgaaagtcctggaatatctataaaattatccgctttgcatcctcgttat
actcgttcgcaatataaggtgctcgtggaggagctttatccccgtttattatcattagca
caaaaagcacggcgttataacatcggtattaatattgatgcagaagaaacagaacgattg
cccatctcgctgagttttttggaaaaattatgttttgagccagatttaaaaggttggagt
ggcattggtttcgtgatccaatcctatcaaaagcgttgcccctttgtgattgatgctctg
attgatttggcaaaacgcagcgaacatcgtttgatgattcgcttggtcaaaggggcatat
tgggatagagaaataaaacatgctcaggtcgaggggctaagcgattatcctgtttataca
cgaaaacctcataccgatatttcatatttagcctgtgctcgtaagttattggctttccct
gagcttatttaccctcagtttgccactcataatgcctatactttggcctccatttattat
ttagctggaggggaaaactatgcgcctgaacaatatgaatttcagtgtttaaatggcatg
ggagaacccctttatcaacacgtggttggggctgtgtcagaaggtggactcaatcggcct
tgtcgtatttatgccccagtggggagtcacaaaacattattggcgtacctggtccgccgc
ttattggaaaatggtgccaatacttcttttgtgaatcgtattgcggatttaaacatacct
ttagagcagctgatacaagatcccgttgaatgggtagaaaaaaaagcggcttcggaagga
acgttagggttgatgaacccaatgatccctcttcctcgagatctatatcatgacactttt
tgtgataaaaaacgtgccaatgcttgtggcgtcgatttatctgatgaacaggtattagcc
tctatttctgaaggattattcgccagtgccaaaaaggtgaaaagcgcttatccgataata
gggttagagccaggaaaaggaggggttgaaaaaaaaatctttaatccagccaatacagag
gatcttgtcggttatgtcagagaagccacgtcaagtgaagccattcgggctttacatttt
gcttgtactacacaagcagaatgggctgaaactccgcctgctgaacgagcaggctttttg
ttaaaagccgcagatgctatggaaagcgaaaaaggcagcttgcttgagttgttaatacgt
gaaacgggtaaaacccttgaaaacgccatcaacgaaattcgtgaagccgttgatttttta
cgttattacgctgtgattgtcgagcaacatttttccaataaaacggaaatccctttgggg
cctgttgtctgtattagcccttggaattttccgctggccatttttacagggcaggtagcc
gccgccctggcttcaggtaattgtgtgttagcaaagcccgcagagcaaacgcctctgatc
gccactgaagtcgttcgtattctttttgaagctggggttcctcgaaaagcattgcaatta
ttaccaggggcgggcgaatctatcgggagcttattggtgaaggatccgcgtgtggcgggc
gtgatgttcacaggctcgacctcagtggctcgtttgatacaaaaccatctttcagaacgt
ttgaataaaaagaaccatcccattccttttattgccgaaacaggtggattaaatgccatg
atcgtcgattcttcggccttaacggaacaggtggtcacggatgtgatgaaatcggctttt
gatagtgccggtcaacgttgttccggcttgcgtattctttgccttcaagaggacattgct
cataaaacgttacatatgttgcggggagcgatggccgcgtatcgtgtgggaaaccctgag
catttttccaccgatatagggcctgtgatagatgcccgggcaaaagagatgattgaaggt
catattcaagcgatgaaagaaaaagggcgaaccgtttatcaggccgctcatttgaataag
ttagataaaaacacggattcgaaggggtatttcatcaagccaactttaattgaactcgac
acgtttgacgaattacaaaaagaaatttttgggcctgtgctccacgtggttcgttttaaa
cgcacggatctcatgactatggtggataaaatcaatgccacaggttatggcttaacatta
ggcatccaaagtcgtattgatgaaaccatttctgaaataacggcccgtgcaaaagtagga
aatatttacgtgaatagaaatatggtcggcgctgtggtaggggtacaaccttttgggggc
gaaggcctttctgggacggggcctaaggctgggggcccactttatctatatcggttgttg
gcgtctcgttccaataaagccttaaatcagactctgcttcaacaaacaaaggagcaaata
tcggatgtggatcaagataaaacaaggctaaacgctcaagaggcttttaaagaatggttg
cgagaacaagacaaatcagaattattagagctcgctcaagagtatatgaaatatacagta
tcgggtcaggcttttcttttgtctggtcctactggggaatctaacacttatcaactctgt
cctcgtgaaaaagtgctctgtttagcagatgacgaaaaagatgcttacattcagctcact
gctgttttagtcgttggaagccaagtgatctggccgaaaaaaaatctccaaactcaattt
tttgcgagtctgccgcccttggtccaacagcgtatcagctttgctgacaataacgactgg
tcctctgatagcctgttttttgatgcggttatccatcatggagatcatgagacactgact
gttttgtgtcaacagttggccaaaagatcaggccctatcgtttctgttcaaggcttatat
caaggagacccacagattcaattagaaaggcttgtcattgagcgttctttgagtattaac
accactgcagcaggaggtaatacttatttaatgacgatgagttaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (15)   
   KEGG COMPOUND (15)   
Chemical reaction (10)   
   KEGG ENZYME (2)   
   KEGG REACTION (8)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (5)   
   Pfam (5)   
All databases (56)   

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