KEGG   Heterocephalus glaber (naked mole rat): 101718355
Entry
101718355         CDS       T02812                                 

Gene name
Mecom
Definition
(RefSeq) MDS1 and EVI1 complex locus
  KO
K04462  ecotropic virus integration site 1 protein
Organism
hgl  Heterocephalus glaber (naked mole rat)
Pathway
hgl04010  MAPK signaling pathway
hgl05200  Pathways in cancer
hgl05220  Chronic myeloid leukemia
Brite
KEGG Orthology (KO) [BR:hgl00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101718355 (Mecom)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101718355 (Mecom)
  09162 Cancer: specific types
   05220 Chronic myeloid leukemia
    101718355 (Mecom)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hgl03000]
    101718355 (Mecom)
Transcription factors [BR:hgl03000]
 Eukaryotic type
  Zinc finger
   Cys2His2 developmental/cell cycle regulators, Krueppel-like
    101718355 (Mecom)
SSDB
Motif
Pfam: zf-C2H2 zf-H2C2_2 zf-C2H2_4 zf-C2H2_6 zf-C2H2_jaz zf-H2C2_5 zf-BED zf-C2H2_8 Zn-ribbon_8 zf-met zf-C2H2_11 Sigma54_activat PyrI_C
Other DBs
NCBI-GeneID: 101718355
NCBI-ProteinID: XP_004834618
UniProt: A0A0P6JA19
Position
Un
AA seq 1239 aa
MRSKGRARKLATSNECVYGNYPEISLEEMPDADGVASTPSLTFQEPCSPATSSEAFTPKE
SSPYKAPIYIPDDIPIPTEFELRESNMPGAGLGIWTKRKIEVGEKFGPYVGEQRSNLKDP
SYGWEILDEFCNVKFCIDASQPDVGSWLKYIRFAGCYDQHNLVACQINDQIFYRVVADIA
PGEELLLFMKSEDYPHETMAPDIHEERQYRCEDCDQLFESKAELADHQKFPCSTPHSAFS
MVEEDFQQKLESENDLREIHTIQECKECDQVFPDLQSLEKHMLSHTEEREYKCDQCPKAF
NWKSNLIRHQMSHDSGKHYECENCAKVFTDPSNLQRHIRSQHVGARAHACPECGKTFATS
SGLKQHKHIHSSVKPFICEVCHKSYTQFSNLCRHKRMHADCRTQIKCKDCGQMFSTTSSL
NKHRRFCEGKNHFAAGGFFGQGISLPGTPAMDKTSMVNMSHANPGLADYFGANRHPAGLT
FPTAPGFSFSFPGLFPSGLYHRPPLIPASSPVKGLPSTEQTNKSQSPLMTHPQILPATQD
ILKALSKHPPVGDNKPVELQPERSSEERALEKISDQSESSDLDDVSTPSGSDLETTSGSD
LESDIESDKEKFKENGKMFKDKVSPLQNLASINNKKEYSNHSIFSPSLEEQTAVSGAVND
SIKAIASIAEKYFGSTGLVGLQDKKVGALPYPSMFPLPFFPAFSQSMYPFPDRDLRSLPL
KMEPQSPSEAKKLQKGNSESPFDLTTKRKDEKPLTPVPSKPPATPATSQDQPLDLSMGSR
SRASGTKLTEPRKNHVFGEKKGSNVEARAASDGSLQHARPTPFFMDPIYRVEKRKLTDPL
EALKEKYLRPSPGFLFHPQFQVPDQRTWMSAIENMAEKLEGFSALKPEASELLQSVPSMF
NFRAPPNTLPENLLRKGKERYTCRYCGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSI
SSNLQRHVRNIHNKEKPFKCHLCDRCFGQQTNLDRHLKKHENGNMSGTATSSPHSELEST
GAILDDKEDAYFTEIRNFIGNSNHSSQSPRNAEERMNGSHFKDEKLLVTSQNSDLLDDEE
VEDEVLLDEEDEDNELMGKTRKEPMTSNLHEGNPEDDFEEASALEMSCKTSPVRYKEEEY
KTGLSALDHIRHFTDSLKMRKMEDNQYTEAELSSFSTSHVPEELKQPLHRKSKSQAYAMM
LSLSDKESLHSASHSSSTVWHSMARAAAESSAIQSISHV
NT seq 3720 nt   +upstreamnt  +downstreamnt
atgagatccaaaggcagggcaaggaaactggccacaagtaatgagtgtgtatatggcaac
taccctgaaatatctttggaagaaatgccagatgcagatggagtagccagcactccctcc
ctcacttttcaagagccatgctctccagccacatccagtgaagcatttactccaaaggag
agctctccttataaagctcccatctacatccctgatgacatccccattcctactgagttt
gaacttcgagagtcaaatatgcctggagcaggactaggaatatggaccaaaaggaagatt
gaagtaggtgaaaagtttggaccttatgtgggagagcagaggtcaaacctgaaagacccc
agttatggatgggagatcttagatgagttttgcaatgtcaagttctgcatagatgccagt
caaccagatgtaggaagctggctcaagtacatcaggttcgctggctgttatgatcagcac
aacctcgttgcatgccagataaatgatcagatattctatagagtagttgcagacattgcg
ccgggagaggagctcctgctgttcatgaagagcgaagactatccccatgaaaccatggca
cctgacatccacgaagaacggcagtatcgatgtgaggactgtgaccagctctttgaatcc
aaagctgaactagcagatcaccagaagtttccctgtagtacacctcactcagcattctca
atggtggaagaagactttcaacaaaaacttgaaagtgaaaatgacctccgagagatacac
accatccaggagtgtaaggaatgtgaccaagtttttcctgatttgcaaagcttggagaaa
cacatgttgtcacatactgaagagagggaatacaagtgtgatcagtgtcccaaggcattt
aactggaagtccaatttaattcgccaccagatgtcacatgacagtggaaagcactatgaa
tgtgagaactgtgccaaggttttcacggaccctagcaaccttcagcggcacattcgctct
cagcacgttggtgcccgggcccatgcatgcccggagtgtggcaaaacgtttgccacttcg
tcaggcctcaaacaacacaagcacatccacagcagtgtgaagccctttatctgtgaggtc
tgccataaatcctatactcagttttcaaacctttgtcgtcataagcgcatgcatgctgat
tgcagaacccaaatcaagtgcaaagactgtggacaaatgttcagcactacgtcttcctta
aataaacacaggaggttttgtgagggcaagaaccattttgcggcaggtggattttttggc
caaggcatttcacttcctggaaccccagctatggataaaacgtccatggttaatatgagt
catgccaacccgggccttgctgactattttggcgccaataggcatcctgctggtcttacc
tttccaacagctcctggattttcttttagcttccctggtctgtttccttccggcttgtac
cacaggcctcctttgatacctgctagttctcctgttaaaggactaccaagtactgaacag
acaaacaaaagtcaaagtcccctcatgacacatcctcagatactgccagctacacaggat
attttgaaggcactatctaaacacccacctgtaggggacaataagccagtggagctccag
cccgagaggtcctctgaagagagggcccttgagaaaatcagtgaccagtcagagagtagt
gaccttgatgatgtcagtacaccaagtggcagtgacctggaaacaacctcgggctctgat
ctggaaagtgacattgaaagtgataaagagaaatttaaagaaaatggtaaaatgttcaaa
gacaaagtaagccctcttcagaatctggcttcaataaataataagaaagaatacagcaat
cattccattttctcaccatctttagaggagcaaactgccgtgtcaggagctgtgaatgat
tctataaaggctattgcttctattgctgaaaaatactttggttcaacaggactggtgggg
ctgcaagacaaaaaagttggagctttaccttacccttccatgtttcccctcccatttttt
ccagcattctctcaatcaatgtacccatttcctgatagagacttgagatcgttacctttg
aaaatggaaccccaatcaccaagtgaagcaaagaaactacagaagggaaactcagagtct
ccctttgatctcaccactaaacgaaaggatgagaagcccttgactcccgtcccctccaag
cctccagcaacacctgccacaagccaagaccagcccctggatctcagtatgggcagtagg
agtagagccagtgggaccaagctgactgagcctcgaaaaaaccatgtatttggggaaaag
aaaggaagcaatgttgaagcaagagcagcttcagatggttccttgcagcatgcaagaccc
actcccttctttatggaccctatttacagagtagagaaaagaaaactaactgacccactt
gaagctttaaaagagaaatacttgagaccttctccaggatttttgtttcacccacaattc
caagtgcctgatcagagaacttggatgtcagctattgaaaacatggcagaaaagctagag
ggcttcagtgccctgaaacctgaggccagtgagctgctacagtcagtgccctccatgttc
aatttcagagcacctcctaataccctgccagagaacctactgcgtaagggaaaagagcgt
tatacctgcagatactgtggtaagatttttccaaggtctgcgaacctaacacggcacttg
agaacccacacaggagagcagccttacagatgcaaatactgtgacagatcatttagcata
tcttcaaacttgcaacgacatgttcgcaacatccacaataaggaaaaaccgtttaaatgt
cacttatgtgataggtgttttggtcagcaaaccaatttagacagacatttaaagaagcat
gagaatgggaacatgtctggtacggcaacatcgtcacctcattctgaactggaaagcaca
ggcgccattctggatgacaaggaagatgcttacttcacagaaattaggaatttcattggg
aatagcaaccacagcagccagtctcccaggaatgcagaggagagaatgaatggcagtcac
tttaaggatgaaaagcttttggtgactagtcaaaattcagacttactggatgatgaagaa
gtggaagacgaggtgttgttggatgaggaggatgaagacaatgaacttatgggaaaaacc
agaaaggaacccatgacaagtaatttacatgaaggaaaccctgaggatgacttcgaagaa
gccagtgccctggagatgagctgtaagacgtccccagtgaggtataaagaggaagaatat
aaaactggactttctgctctagatcacataaggcacttcacagatagcctcaaaatgagg
aaaatggaagataatcaatatactgaagctgagctgtcttcttttagtacttcccatgtg
ccagaggaacttaaacagccgttacacagaaagtccaaatcacaggcatatgctatgatg
ttgtcattgtccgacaaggagtccctccattctgcatctcacagttcttccaccgtgtgg
cacagcatggcaagggctgcagcagaatccagtgccatccagtccataagccacgtatga

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