KEGG   Halobacillus halophilus: HBHAL_2573
Entry
HBHAL_2573        CDS       T02031                                 
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
hhd  Halobacillus halophilus
Pathway
hhd00290  Valine, leucine and isoleucine biosynthesis
hhd00620  Pyruvate metabolism
hhd01100  Metabolic pathways
hhd01110  Biosynthesis of secondary metabolites
hhd01210  2-Oxocarboxylic acid metabolism
hhd01230  Biosynthesis of amino acids
Module
hhd_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:hhd00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    HBHAL_2573 (leuA)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    HBHAL_2573 (leuA)
Enzymes [BR:hhd01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     HBHAL_2573 (leuA)
SSDB
Motif
Pfam: HMGL-like LeuA_dimer DUF386 Suv3_N
Other DBs
NCBI-ProteinID: CCG44919
UniProt: I0JL99
Position
1581438..1582985
AA seq 515 aa
MAHVNVFDTTLRDGEQSAGVNLDRLEKLEIAKQLERLGVDIMEAGFPASSQGEFESVREI
ANTVRSVSVTGLARAHKKDIDIAWEALKGGAEPRLHVFLATSAIHMTHKLKKTPDEVVET
AVEAVSYAKEKFPHVQWSAEDASRTDIDFLVHIIEKVIDAGASVINLPDTVGYSTPDEYG
RMFREVRERVPNIDQAILSAHCHDDLGMAVSNSIAAIENGVRQIEGTINGIGERAGNAAL
EEIGVALEIRKDRYDYQTNLVLKEIKRTSDLVSRMTGMMVPGNKAVVGRNAFAHESGIHQ
DGMLKDSSTYEIITPAMVGIDSNRMVMGKHSGRHAFKQKAESMGYELTDEKLKEAFESFK
NLTAKKKEVTDDDLFAILTDTQTEDKDQPKYELKAFQVQYGSINRPTATVLLTKPDGEEV
EKANTGDGSVEAIYNTLDDLIDADVHLQDYQLSSIGRGRDALAEVHVQLTVDDVKASGRG
SAQDVLEASAHAFLNAVNRTLYRKNTEPVQKQVHV
NT seq 1548 nt   +upstreamnt  +downstreamnt
atggctcacgttaacgtattcgatacaactcttagagacggagaacagtcagctggcgta
aacttggaccgcctggaaaaattggagattgcgaagcagctggaacgccttggggtagac
attatggaagcaggattccctgcttcctcccagggagagtttgaatccgtccgtgagatt
gcgaacacggtgagaagcgtttcagtaacgggacttgcgagagctcacaagaaagatatc
gacattgcctgggaagctttgaaaggcggagcagaaccaagacttcacgttttcttggct
acctcagccattcatatgacgcataagcttaagaaaacaccagatgaagtggtggaaaca
gcggtagaagctgtatcttacgcgaaagagaaattccctcacgttcagtggtccgcagag
gatgcgagccgaaccgatatcgatttccttgttcatatcattgagaaagtcattgacgct
ggtgcatccgtcattaaccttccggacacggtcggatattctacgccggatgaatacgga
cgcatgttccgtgaagtgagagaacgcgttccgaatatcgatcaggcgattctttccgct
cactgccatgacgatcttggtatggctgtcagcaactcgattgcggctattgaaaacgga
gtgcgccagatcgaaggcaccattaacgggattggcgaacgtgctggaaacgcggcactg
gaggaaatcggagtcgctcttgaaatccgtaaagaccgttacgattatcagacgaacctt
gtattaaaagaaattaaaagaacgagtgatttggtcagccgtatgaccggtatgatggtt
ccgggtaacaaagcagttgtcggccgtaacgcctttgctcacgaatccggtattcaccag
gacggtatgctgaaagactcgtccacttacgaaatcatcacaccagcgatggtgggaatc
gattccaaccgaatggtgatgggtaaacactcaggtcgtcacgctttcaaacaaaaagcc
gaatcaatgggctatgagttgacggatgagaaattgaaagaagcgttcgaatccttcaag
aacttgacggcgaagaagaaagaagttaccgacgacgatttgtttgctatcttgaccgat
acgcagaccgaagacaaagatcagccgaaatacgagctgaaagccttccaggttcaatac
ggaagcatcaatcgtccgacagccacggtacttcttaccaagccggatggcgaagaagtc
gagaaagccaatacaggagacggcagtgtagaagccatctacaacacgctggatgattta
atcgatgccgacgtgcatttgcaggattaccagttaagctcgattggaagaggacgagat
gcactggcagaagttcacgtgcagctaacagtagatgatgtgaaagcttccgggcgcgga
tctgctcaggatgttctagaagcatctgcccatgctttcttaaacgccgtaaaccgcaca
ttatatagaaagaacacggaaccagttcaaaagcaggttcacgtataa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (7)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (4)   
   Pfam (4)   
All databases (29)   

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