KEGG   Hydra vulgaris (swiftwater hydra): 100214280
Entry
100214280         CDS       T01080                                 
Name
(RefSeq) DNA topoisomerase 2-alpha isoform X1
  KO
K03164  DNA topoisomerase II [EC:5.6.2.2]
Organism
hmg  Hydra vulgaris (swiftwater hydra)
Brite
KEGG Orthology (KO) [BR:hmg00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:hmg03032]
    100214280
   03036 Chromosome and associated proteins [BR:hmg03036]
    100214280
Enzymes [BR:hmg01000]
 5. Isomerases
  5.6  Isomerases altering macromolecular conformation
   5.6.2  Enzymes altering nucleic acid conformation
    5.6.2.2  DNA topoisomerase (ATP-hydrolysing)
     100214280
DNA replication proteins [BR:hmg03032]
 Eukaryotic type
  DNA Topoisomerases
   100214280
Chromosome and associated proteins [BR:hmg03036]
 Eukaryotic type
  Chromosome condensation proteins
   Other regulators of chromosome condensation
    100214280
  Centrosome formation proteins
   Centriole proteins
    100214280
SSDB
Motif
Pfam: DNA_topoisoIV TOPRIM_C DNA_gyraseB HATPase_c Toprim
Other DBs
NCBI-GeneID: 100214280
NCBI-ProteinID: XP_047132969
Position
5:31705055..31750798
AA seq 1685 aa
MDSTLKCRSRVTLKTFNRWEFAKEFQIETITEEENTYVVKMKCNLCALHRNTILLRISGA
VKAAALLFINGTSHIKKDSASRHIKGATHQYAMHLENEDFDKYKDGTKNDIDMNIDSVVP
MKNKRLSVERIYQKKSQLEHIILRPDSYIGSTEPCQQSMWVWDDESSSIISKNITFSPGL
YKIFDEIIVNAADNKQRDVKMNTIKVNIDVEKNIISVWNNGRGIPVEMHKEQNVYVPTLI
FGHLLTSSNYDDTEKKVVGGRNGFGAKLCNIFSTKFSIETGCDGKKFKQVWKNNMSKAEP
EHIVDYSGSDFTCVTFSPDLPKFKMDKLDNDFVSLLKRRAYDMAGVCRGVSVYLNGEKLK
VKSFKDYVGLYVKTACKTENGEEQGPKIIHEIVNPRWEICVTVSESGFQHSSFVNSIATT
KGGTHVTYIVDQLCDKLIATVKKKTGKGGFDIKPFHVKSHLWVFVNTLIENPTFDSQTKE
NMTLRKSAFGSTCELSDKYIKMVQDTGVLENILSWVKFKSEAQLNKKGSSSKHSRLKGVP
KLEDANDAGTKRSRDCTLIVTEGDSAKALVMAGLSVVGRDKYGVFPLRGKLLNVRDASHS
QIMNNAEIGSLVKIIGLQFGKKYENENDMKTLRYGHLMIMADQDQDGSHIKGLVINFIHA
NWPGLLKIPFLEEFITPIIKASKSKKETISFFSIPEFEEWKEATPNYKSWHIKYYKGLGS
STSIEGKEYFSDMQRHRIVFEYDGPSSDEALILAFSKKCANERKNWLDNGLAERKLRREA
GLPEVYLYEKGTRTVTYQDFINKELILFSNTDNERSIPSLVDGFKPGQRKVLFTCMKRND
KREVKVAQLAGSVAELSAYHHGEMSLMGTIVNLAQNFVGSNNLNVLLPIGQFGTRHVGGK
DSASPRYIFTMMSSLTRLVFPEKDDAVLTYLFDDNQKIEPEWYCPIIPMCLVNGAEGIGT
GYSTKIPNFDIRDIVENVKRMINGEEPQPMFPSYKDFTGEIVQEGDQKFICQGTINIIDE
TTIEITELPVRTWTQAYKETVLDVYLYGNEKSPPCITDYKEYHTDSTVKFVITMTPEQMV
KAEEEGLHKKFKLLSSINLSCMVLFDEFGCIKKYESPTEIMKAFFNVRMAKYNERKKFIL
GMLEAECSKLENQARFILEKIEGKIIIENRSKRDVITTLVERGYVSDPVKAWKAEVDKSG
HLEDDSEAPTTDVASSSSSLSGPDFAYLLSMAIMSLSREKKEELLNQRDEKKKELNALKQ
KTPSDLWTDDLNKFCEELERVEEQEKELNRAVDALSNKSNSRSTKGNKAKKVPVKSKDIA
KAFEKKSDTKVLPVKDASSNVIKSEPSEQSQENDNEDKGEILSLADRLKKNISEGKKKQA
PLSFKPSKPKKAKFVVHSDSDNEDDDDEFKIEDFSGETEFSVDPPKRDTRKKEIKKYFDD
SDNPSDNDNVSEVSPTVLQSKNLNVSTDSENSDEAQTRALIQKLSPVKKKTYSADKKIQS
VVEDKGTESKPILLSDSPSKSKKTEKKKPDKKLAKKTDVKQSLISFGPSIPTASANLDLE
KKVTTKTKPTVSKSVAKRPLSEDESDPLSPKTKKSKKKNNIKPKQDEDKPPKSNKPKPAK
TVIKALPKKTKKLNTDSEGDDDSFRLDDIPAVAPRSRGAGRAASKKVVYKFSSDEDDDAD
DDFAV
NT seq 5058 nt   +upstreamnt  +downstreamnt
atggatagtactttgaaatgccgcagcagagtcactttaaagacttttaatcgctgggag
tttgcaaaggaatttcaaattgaaaccattacagaagaagaaaatacttatgtagttaaa
atgaaatgtaatttatgtgctcttcatagaaatactattttattaagaattagtggagca
gtcaaggcagctgccttgctatttataaatggtacgagtcatattaaaaaagatagcgct
agtagacatataaaaggagcgactcaccaatatgcaatgcatttggaaaatgaagatttt
gacaaatataaagatggaacaaaaaatgatattgacatgaatattgatagcgttgttcca
atgaagaacaaaagactctctgttgagaggatttatcaaaaaaaatctcagttagagcat
ataattttgcgtcctgattcatacattggatctacagaaccatgccaacaaagtatgtgg
gtttgggatgatgaaagcagttctattatttcaaagaatattacattctctccagggtta
tacaaaatttttgatgaaatcattgtaaacgcagctgacaataagcaacgtgatgttaaa
atgaatacaatcaaagttaatatagatgttgaaaaaaatattataagtgtctggaataat
ggccgtggtattccagtagaaatgcataaagagcagaatgtatatgttcccacactaatc
tttggccatttgctgacttcaagcaactatgatgatactgaaaaaaaagttgttggagga
agaaatggttttggagctaagttatgtaatatttttagcactaaattttctattgaaact
ggatgtgatggaaaaaagtttaaacaggtatggaagaacaatatgagtaaagctgagcct
gaacatattgtagattactcaggcagtgatttcacttgtgtaacattttcaccagattta
cctaagttcaaaatggataaactagacaatgattttgtttcattgttgaagaggcgtgca
tacgacatggctggagtatgccgaggagtttctgtatatcttaatggtgaaaaactaaaa
gtaaaatcatttaaagactatgttggattgtatgtcaagactgcttgcaaaactgaaaat
ggggaagaacaaggtccgaagattatacatgaaattgttaatccacgatgggagatatgt
gtaacagttagtgagagtgggttccaacattctagctttgtaaacagcattgccactacc
aagggtggaactcatgtcacgtacattgttgatcaactatgtgataaactaattgcgact
gttaaaaaaaaaactggtaaaggtggttttgatatcaaaccatttcatgttaagtctcat
ctttgggtgtttgttaacactcttattgaaaatcctacatttgattcgcaaacaaaagaa
aatatgacactgcgaaagtctgcatttggttcaacttgtgaactttcagataaatatata
aaaatggtgcaagatactggggtcttggaaaatattttatcttgggtaaagtttaagagt
gaggcacaactcaataaaaagggatcttcttcaaaacacagcagattaaaaggtgttcct
aaactagaagatgcaaatgatgctggcacaaagaggtcaagagattgtacacttattgtt
actgagggagactcagctaaagcccttgttatggcaggtttaagtgtagttgggcgagat
aaatatggtgtctttcctttaagaggtaaactgttgaatgtcagagatgcttcacattct
cagattatgaacaatgctgaaataggaagtttagttaagatcattggtttgcagtttggt
aaaaaatacgagaatgagaatgatatgaaaacattgcgttatggacatctgatgattatg
gctgatcaagatcaagatggttctcatattaaaggtcttgtcattaactttatacatgca
aattggccaggcttgttgaaaattccttttcttgaagaatttattacacctattattaag
gcatcaaaaagtaaaaaggaaactatttcatttttttccatacctgagtttgaagagtgg
aaagaagcaactccaaattataaatcatggcacataaagtactacaaaggtttgggtagt
tcaacaagtatagaaggtaaagaatatttttcagatatgcaaagacacagaatagttttt
gagtatgatgggccctcatctgatgaagcactaattttggcatttagtaaaaaatgtgca
aatgaaaggaaaaattggctagacaatggacttgctgaaagaaaattacgacgagaagca
ggtctacctgaagtttatctttatgaaaaaggaactcgaactgtaacataccaagatttc
attaataaagagcttattcttttttcaaatactgataatgaacgctcaattccttcactt
gttgatggtttcaaacctggtcaacggaaagttttgtttacttgtatgaaaaggaatgac
aaaagagaggttaaagttgcccaacttgctggttctgttgctgaactatcagcatatcac
catggtgaaatgagtttgatgggaacaatagtaaacttagcgcaaaactttgtaggcagt
aataatctaaatgtgctgcttccaattggtcaatttggtactcgacatgttggtggtaaa
gatagtgcttctcctcgttacatttttacaatgatgagttcattaacaagacttgttttc
ccagaaaaagatgatgcggtcctaacttacctttttgatgataaccagaaaattgagcca
gaatggtattgtcctataattccaatgtgtcttgtcaatggtgctgaaggtattggaact
ggttattctactaaaattccaaattttgacataagagatattgttgaaaatgtaaaaaga
atgattaatggtgaagaaccacagcctatgtttccttcatataaagactttactggtgaa
attgtgcaagaaggagatcaaaagtttatatgtcaaggaaccataaatattatagatgaa
acaacaatcgaaataacagagcttcctgtcagaacatggactcaagcttataaagaaact
gttttggatgtatatctttatggaaatgaaaaatctccaccatgtataacagattataaa
gagtatcatacagattcaactgtaaaatttgttatcacaatgacacctgaacaaatggtt
aaagctgaggaagagggattgcataaaaagttcaagttgctttcatcgataaatttatca
tgcatggttctttttgatgagtttggatgcataaaaaagtatgaaagtccaacagaaatt
atgaaagctttttttaatgttcgaatggctaagtataatgagcggaaaaagtttattttg
ggaatgcttgaagctgaatgttcaaagttggaaaatcaagcaaggtttatattggaaaaa
atagaaggaaaaatcataattgaaaatcgcagtaaacgtgatgtaatcaccacacttgtt
gaaagagggtatgtttctgacccagttaaagcatggaaagccgaagtggacaaatctggt
catttagaagatgatagtgaggcacctacaacagatgtagctagctcatcttcatcacta
tctggaccagattttgcatatcttctgtccatggctatcatgagcttgtctcgtgagaaa
aaagaagagttactcaatcagagagatgaaaaaaaaaaagaactcaatgcgcttaaacaa
aagacaccatctgatttgtggacggatgatctcaataagttttgtgaagaacttgagagg
gttgaagagcaagagaaagaactaaatagagctgttgatgctctttctaataaaagtaat
agtcgctctactaaaggtaataaagctaaaaaagtccctgttaaaagtaaagatatagca
aaagcttttgagaaaaaatctgacaccaaagttttgccagtaaaagatgcatcttctaat
gttattaaaagtgaaccaagtgaacaaagtcaagaaaatgataatgaagataaaggagag
attttatctcttgctgacagacttaagaaaaatatcagtgaaggcaaaaaaaaacaagct
ccgttatcttttaaacctagcaagcccaaaaaagcaaaatttgtagttcatagtgacagt
gataatgaagatgatgatgatgaatttaaaattgaagatttttccggagagacagagttt
tctgttgatccaccaaagcgagatacacgaaaaaaggaaatcaagaaatatttcgatgat
tctgataatccaagtgataatgataatgtttctgaagtttctccaactgttttacaaagt
aaaaaccttaatgtatcaactgattctgagaattctgacgaggcccaaacacgtgcgtta
attcaaaaactctctccggtgaagaaaaaaacatattctgctgataaaaaaattcaatct
gtagttgaagataaagggaccgaaagcaagccaatattgcttagtgattctccatctaag
agtaaaaaaacagaaaaaaagaaacctgacaaaaagttagcaaaaaaaaccgatgttaaa
caatctttgatatcatttggaccaagtatacctactgcatcagcaaatctggatttagaa
aaaaaggttactacaaaaacaaagccgactgtatctaaatcagtagctaagcgtccactt
tcagaagatgaaagtgatccattatcacctaaaacgaaaaaatctaaaaaaaaaaataac
ataaaaccaaagcaagatgaagacaagccaccgaaatcaaacaaaccaaaaccagcaaag
acagtaataaaagctttacctaaaaaaaccaaaaaattgaacactgatagtgaaggcgat
gacgattcttttcgtttggacgatataccggcagttgctccgcgttctcgaggtgctggt
cgtgctgcatctaagaaagttgtatataagtttagttccgatgaagatgacgatgcagat
gacgactttgctgtttaa

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (108)   
   KEGG ORTHOLOGY (1)   
   RefGene (104)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   RefSeq(pep) (2)   
DNA sequence (4)   
   RefSeq(nuc) (2)   
   GenBank (1)   
   EMBL (1)   
Protein domain (5)   
   Pfam (5)   
All databases (125)   

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