KEGG   Halothermothrix orenii: Hore_10860
Entry
Hore_10860        CDS       T00838                                 
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
hor  Halothermothrix orenii
Pathway
hor00290  Valine, leucine and isoleucine biosynthesis
hor00620  Pyruvate metabolism
hor01100  Metabolic pathways
hor01110  Biosynthesis of secondary metabolites
hor01210  2-Oxocarboxylic acid metabolism
hor01230  Biosynthesis of amino acids
Module
hor_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:hor00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    Hore_10860
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    Hore_10860
Enzymes [BR:hor01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     Hore_10860
SSDB
Motif
Pfam: HMGL-like LeuA_dimer
Other DBs
NCBI-ProteinID: ACL69840
UniProt: B8CX21
Position
1179756..1181303
AA seq 515 aa
MGEVKIFDTTLRDGEQSPGVSLIPEEKLAIAKQLARMKVDVIEAGFPISSPGDFEAVQII
SENIRDVEVAALARSRKKDIDRAWEALRNGGDPRIHVFIATSPIHMKYKLKLSEEQVIEK
AVEAVKYASKYTSNIEFSAEDASRSQPVFLYRLFERVINAGAKVINIPDTVGYAIPEEFG
KLIRDIKENVSNIDKVDISVHCHNDLGLAVANSLAAVENGANQIEVAVNGIGERAGNTAL
EEIIMALYTRKDFYNIGINQDTTQIARLSKLVSNLTGMTIQPNKAIVGANAFAHESGIHQ
DGVIKERTTYEIMDARTIGLKDNKLVLGKHSGRHAFREFIQKLGYDIDDETFEEIFIEFK
KLADKKKNITHVEIEALIDNHYHTFDKVYELDYLSVNTGNKVLPTATIKLKKENNIIEKA
ACSGDGPVDAIFQAINEIVGIDDIKLISYHINAVTEGKDALGEVIVKTKIEDNTYTGHSA
MTDITEASALAYLETINKFLTSEQTRQTTSAQEGI
NT seq 1548 nt   +upstreamnt  +downstreamnt
atgggtgaggttaaaatatttgatacaacgttaagggatggcgagcagtctcccggcgtc
agtcttattcctgaagaaaaacttgctatagctaaacagctcgccaggatgaaagttgat
gttattgaggcaggttttccaatttcttcaccgggggattttgaggctgttcagattatc
agcgagaatatcagagatgttgaggtggctgccctggcccggagcaggaaaaaggatata
gaccgggcctgggaagcactaagaaatggaggggatcctagaattcatgtatttattgct
acctctcctattcatatgaaatataaattaaaattgtctgaggaacaggttatagaaaaa
gcagttgaggctgtaaaatatgcctctaaatacacatccaatattgaattttctgctgag
gatgcttcccggagccaacctgtttttttatatcggctctttgaaagggttattaatgcg
ggggcgaaggttattaatatacctgatactgtcggttatgcgattcctgaagagtttggt
aaattaataagagatataaaagaaaatgtttccaatattgataaggttgatatcagtgtt
cactgccataacgacctcggtctggctgtggccaatagtctggcggcggtagagaatgga
gccaaccagattgaggttgctgttaatggtattggtgaaagggcaggtaatacagcactt
gaagagattattatggccctttatacccggaaggatttttacaatatcgggataaaccag
gatacaacccagattgcgagattgagcaaactggtttcaaatttaaccgggatgactatc
cagcccaataaagctattgtcggggccaatgcttttgcccatgaatcaggtattcaccag
gatggtgtcattaaagaaagaactacctatgaaattatggatgcccggacaataggtctt
aaggataataaactggttctgggtaaacattcaggacgacatgcctttcgggagtttatt
caaaaacttggttatgatatagatgacgaaacttttgaagagatttttattgaatttaag
aaactggctgataagaagaaaaatattacccatgttgaaattgaagcacttatcgataat
cattatcatacttttgataaggtttatgaactggattacttatcggttaataccggtaac
aaagttctaccgacagcgacaataaagcttaaaaaggagaataatatcattgaaaaagct
gcctgtagtggtgatggaccggttgatgctatttttcaggctatcaatgaaattgtcggt
atagatgatattaaattaatttcataccatattaatgctgttactgaaggtaaggatgcc
ctgggtgaagttatagttaaaactaaaattgaggataacacctatactggacatagtgct
atgactgatattactgaagccagtgcccttgcttatctcgaaaccattaataaattttta
acatcagaacaaacaaggcagacaacttctgcacaagaaggcatttaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   SWISS-PROT (1)   
Protein domain (2)   
   Pfam (2)   
All databases (26)   

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