KEGG   Homo sapiens (human): 2525
Entry
2525              CDS       T01001                                 
Symbol
FUT3, CD174, FT3B, FucT-III, LE, Les
Name
(RefSeq) fucosyltransferase 3 (Lewis blood group)
  KO
K00716  galactoside 3(4)-fucosyltransferase 3 [EC:2.4.1.65]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00601  Glycosphingolipid biosynthesis - lacto and neolacto series
hsa01100  Metabolic pathways
Network
nt06035  Blood group carbohydrate antigen biosynthesis
  Element
N01659  Lewis b antigen biosynthesis
N01660  Lewis a antigen biosynthesis
N01661  Sialyl lewis a antigen biosynthesis
N01664  Blood group A/B Lewis b antigen biosynthesis
N01669  Blood group A/B Lewis y antigen biosynthesis
N01672  Lewis x antigen biosynthesis
N01673  Lewis y antigen biosynthesis
N01674  Sialyl lewis x antigen biosynthesis
N01700  Lewis negative, Le (a-b-)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00601 Glycosphingolipid biosynthesis - lacto and neolacto series
    2525 (FUT3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases [BR:hsa01003]
    2525 (FUT3)
Enzymes [BR:hsa01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.65  3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase
     2525 (FUT3)
Glycosyltransferases [BR:hsa01003]
 Glycan extension
  Lewis blood group
   2525 (FUT3)
SSDB
Motif
Pfam: Glyco_transf_10 Glyco_tran_10_N Hormone_3
Other DBs
NCBI-GeneID: 2525
NCBI-ProteinID: NP_000140
OMIM: 111100
HGNC: 4014
Ensembl: ENSG00000171124
UniProt: P21217 A8K737
Position
19:complement(5842888..5857122)
AA seq 361 aa
MDPLGAAKPQWPWRRCLAALLFQLLVAVCFFSYLRVSRDDATGSPRAPSGSSRQDTTPTR
PTLLILLWTWPFHIPVALSRCSEMVPGTADCHITADRKVYPQADTVIVHHWDIMSNPKSR
LPPSPRPQGQRWIWFNLEPPPNCQHLEALDRYFNLTMSYRSDSDIFTPYGWLEPWSGQPA
HPPLNLSAKTELVAWAVSNWKPDSARVRYYQSLQAHLKVDVYGRSHKPLPKGTMMETLSR
YKFYLAFENSLHPDYITEKLWRNALEAWAVPVVLGPSRSNYERFLPPDAFIHVDDFQSPK
DLARYLQELDKDHARYLSYFRWRETLRPRSFSWALDFCKACWKLQQESRYQTVRSIAAWF
T
NT seq 1086 nt   +upstreamnt  +downstreamnt
atggatcccctgggtgcagccaagccacaatggccatggcgccgctgtctggccgcactg
ctatttcagctgctggtggctgtgtgtttcttctcctacctgcgtgtgtcccgagacgat
gccactggatcccctagggctcccagtgggtcctcccgacaggacaccactcccacccgc
cccaccctcctgatcctgctatggacatggcctttccacatccctgtggctctgtcccgc
tgttcagagatggtgcccggcacagccgactgccacatcactgccgaccgcaaggtgtac
ccacaggcagacacggtcatcgtgcaccactgggatatcatgtccaaccctaagtcacgc
ctcccaccttccccgaggccgcaggggcagcgctggatctggttcaacttggagccaccc
cctaactgccagcacctggaagccctggacagatacttcaatctcaccatgtcctaccgc
agcgactccgacatcttcacgccctacggctggctggagccgtggtccggccagcctgcc
cacccaccgctcaacctctcggccaagaccgagctggtggcctgggcggtgtccaactgg
aagccggactcagccagggtgcgctactaccagagcctgcaggctcatctcaaggtggac
gtgtacggacgctcccacaagcccctgcccaaggggaccatgatggagacgctgtcccgg
tacaagttctacctggccttcgagaactccttgcaccccgactacatcaccgagaagctg
tggaggaacgccctggaggcctgggccgtgcccgtggtgctgggccccagcagaagcaac
tacgagaggttcctgccacccgacgccttcatccacgtggacgacttccagagccccaag
gacctggcccggtacctgcaggagctggacaaggaccacgcccgctacctgagctacttt
cgctggcgggagacgctgcggcctcgctccttcagctgggcactggatttctgcaaggcc
tgctggaaactgcagcaggaatccaggtaccagacggtgcgcagcatagcggcttggttc
acctga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Network (10)   
   KEGG NETWORK (10)   
Disease (2)   
   OMIM (2)   
Chemical reaction (19)   
   KEGG ENZYME (1)   
   KEGG REACTION (18)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   RefGene (11)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (15)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (12)   
DNA sequence (88)   
   RefSeq(nuc) (12)   
   GenBank (38)   
   EMBL (38)   
Protein domain (3)   
   Pfam (3)   
All databases (161)   

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