KEGG   Homo sapiens (human): 5641
Entry
5641              CDS       T01001                                 
Symbol
LGMN, AEP, LGMN1, PRSC1
Name
(RefSeq) legumain
  KO
K01369  legumain [EC:3.4.22.34]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04142  Lysosome
hsa04612  Antigen processing and presentation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04142 Lysosome
    5641 (LGMN)
 09150 Organismal Systems
  09151 Immune system
   04612 Antigen processing and presentation
    5641 (LGMN)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    5641 (LGMN)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.34  legumain
     5641 (LGMN)
Peptidases and inhibitors [BR:hsa01002]
 Cysteine peptidases
  Family C13: legumain family
   5641 (LGMN)
SSDB
Motif
Pfam: Peptidase_C13 Legum_prodom Phage_T7_55
Other DBs
NCBI-GeneID: 5641
NCBI-ProteinID: NP_001008530
OMIM: 602620
HGNC: 9472
Ensembl: ENSG00000100600
UniProt: Q99538 Q53XC6
Structure
Position
14:complement(92703809..92748627)
AA seq 433 aa
MVWKVAVFLSVALGIGAVPIDDPEDGGKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNG
IPDEQIVVMMYDDIAYSEDNPTPGIVINRPNGTDVYQGVPKDYTGEDVTPQNFLAVLRGD
AEAVKGIGSGKVLKSGPQDHVFIYFTDHGSTGILVFPNEDLHVKDLNETIHYMYKHKMYR
KMVFYIEACESGSMMNHLPDNINVYATTAANPRESSYACYYDEKRSTYLGDWYSVNWMED
SDVEDLTKETLHKQYHLVKSHTNTSHVMQYGNKTISTMKVMQFQGMKRKASSPVPLPPVT
HLDLTPSPDVPLTIMKRKLMNTNDLEESRQLTEEIQRHLDARHLIEKSVRKIVSLLAASE
AEVEQLLSERAPLTGHSCYPEALLHFRTHCFNWHSPTYEYALRHLYVLVNLCEKPYPLHR
IKLSMDHVCLGHY
NT seq 1302 nt   +upstreamnt  +downstreamnt
atggtttggaaagtagctgtattcctcagtgtggccctgggcattggtgccgttcctata
gatgatcctgaagatggaggcaagcactgggtggtgatcgtggcaggttcaaatggctgg
tataattataggcaccaggcagacgcgtgccatgcctaccagatcattcaccgcaatggg
attcctgacgaacagatcgttgtgatgatgtacgatgacattgcttactctgaagacaat
cccactccaggaattgtgatcaacaggcccaatggcacagatgtctatcagggagtcccg
aaggactacactggagaggatgttaccccacaaaatttccttgctgtgttgagaggcgat
gcagaagcagtgaagggcataggatccggcaaagtcctgaagagtggcccccaggatcac
gtgttcatttacttcactgaccatggatctactggaatactggtttttcccaatgaagat
cttcatgtaaaggacctgaatgagaccatccattacatgtacaaacacaaaatgtaccga
aagatggtgttctacattgaagcctgtgagtctgggtccatgatgaaccacctgccggat
aacatcaatgtttatgcaactactgctgccaaccccagagagtcgtcctacgcctgttac
tatgatgagaagaggtccacgtacctgggggactggtacagcgtcaactggatggaagat
tcggacgtggaagatctgactaaagagaccctgcacaagcagtaccacctggtaaaatcg
cacaccaacaccagccacgtcatgcagtatggaaacaaaacaatctccaccatgaaagtg
atgcagtttcagggtatgaaacgcaaagccagttctcccgtccccctacctccagtcaca
caccttgacctcacccccagccctgatgtgcctctcaccatcatgaaaaggaaactgatg
aacaccaatgatctggaggagtccaggcagctcacggaggagatccagcggcatctggat
gccaggcacctcattgagaagtcagtgcgtaagatcgtctccttgctggcagcgtccgag
gctgaggtggagcagctcctgtccgagagagccccgctcacggggcacagctgctaccca
gaggccctgctgcacttccggacccactgcttcaactggcactcccccacgtacgagtat
gcgttgagacatttgtacgtgctggtcaacctttgtgagaagccgtatccgcttcacagg
ataaaattgtccatggaccacgtgtgccttggtcactactga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (21)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (18)   
DNA sequence (50)   
   RefSeq(nuc) (18)   
   GenBank (16)   
   EMBL (16)   
3D Structure (18)   
   PDB (18)   
Protein domain (3)   
   Pfam (3)   
All databases (119)   

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