KEGG   Homo sapiens (human): 6517
Entry
6517              CDS       T01001                                 
Symbol
SLC2A4, GLUT4
Name
(RefSeq) solute carrier family 2 member 4
  KO
K07191  MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
Organism
hsa  Homo sapiens (human)
Pathway
hsa04068  FoxO signaling pathway
hsa04152  AMPK signaling pathway
hsa04910  Insulin signaling pathway
hsa04920  Adipocytokine signaling pathway
hsa04930  Type II diabetes mellitus
hsa04931  Insulin resistance
hsa05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    6517 (SLC2A4)
   04152 AMPK signaling pathway
    6517 (SLC2A4)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    6517 (SLC2A4)
   04920 Adipocytokine signaling pathway
    6517 (SLC2A4)
 09160 Human Diseases
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    6517 (SLC2A4)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    6517 (SLC2A4)
   04931 Insulin resistance
    6517 (SLC2A4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hsa02000]
    6517 (SLC2A4)
Transporters [BR:hsa02000]
 Solute carrier family (SLC)
  SLC2: Facilitative GLUT transporter
   6517 (SLC2A4)
 Major facilitator superfamily (MFS)
  Sugar transporters
   Sugar porter (SP) family [TC:2.A.1.1]
    6517 (SLC2A4)
SSDB
Motif
Pfam: Sugar_tr MFS_1
Other DBs
NCBI-GeneID: 6517
NCBI-ProteinID: NP_001033
OMIM: 138190
HGNC: 11009
Ensembl: ENSG00000181856
UniProt: P14672
Structure
Position
17:7281718..7288257
AA seq 509 aa
MPSGFQQIGSEDGEPPQQRVTGTLVLAVFSAVLGSLQFGYNIGVINAPQKVIEQSYNETW
LGRQGPEGPSSIPPGTLTTLWALSVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAV
LGGSLMGLANAAASYEMLILGRFLIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAI
VIGILIAQVLGLESLLGTASLWPLLLGLTVLPALLQLVLLPFCPESPRYLYIIQNLEGPA
RKSLKRLTGWADVSGVLAELKDEKRKLERERPLSLLQLLGSRTHRQPLIIAVVLQLSQQL
SGINAVFYYSTSIFETAGVGQPAYATIGAGVVNTVFTLVSVLLVERAGRRTLHLLGLAGM
CGCAILMTVALLLLERVPAMSYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAM
AVAGFSNWTSNFIIGMGFQYVAEAMGPYVFLLFAVLLLGFFIFTFLRVPETRGRTFDQIS
AAFHRTPSLLEQEVKPSTELEYLGPDEND
NT seq 1530 nt   +upstreamnt  +downstreamnt
atgccgtcgggcttccaacagataggctccgaagatggggaaccccctcagcagcgagtg
actgggaccctggtccttgctgtgttctctgcggtgcttggctccctgcagtttgggtac
aacattggggtcatcaatgcccctcagaaggtgattgaacagagctacaatgagacgtgg
ctggggaggcaggggcctgagggacccagctccatccctccaggcaccctcaccaccctc
tgggccctctccgtggccatcttttccgtgggcggcatgatttcctccttcctcattggt
atcatctctcagtggcttggaaggaaaagggccatgctggtcaacaatgtcctggcggtg
ctggggggcagcctcatgggcctggccaatgctgctgcctcctatgaaatgctcatcctt
ggacgattcctcattggcgcctactcagggctgacatcagggctggtgcccatgtacgtg
ggggagattgctcccactcacctgcggggcgccctggggacgctcaaccaactggccatt
gttatcggcattctgatcgcccaggtgctgggcttggagtccctcctgggcactgccagc
ctgtggccactgctcctgggcctcacagtgctacctgccctcctgcagctggtcctgctg
cccttctgtcccgagagcccccgctacctctacatcatccagaatctcgaggggcctgcc
agaaagagtctgaagcgcctgacaggctgggccgatgtttctggagtgctggctgagctg
aaggatgagaagcggaagctggagcgtgagcggccactgtccctgctccagctcctgggc
agccgtacccaccggcagcccctgatcattgcggtcgtgctgcagctgagccagcagctc
tctggcatcaatgctgttttctattattcgaccagcatcttcgagacagcaggggtaggc
cagcctgcctatgccaccataggagctggtgtggtcaacacagtcttcaccttggtctcg
gtgttgttggtggagcgggcggggcgccggacgctccatctcctgggcctggcgggcatg
tgtggctgtgccatcctgatgactgtggctctgctcctgctggagcgagttccagccatg
agctacgtctccattgtggccatctttggcttcgtggcattttttgagattggccctggc
cccattccttggttcatcgtggccgagctcttcagccagggaccccgcccggcagccatg
gctgtggctggtttctccaactggacgagcaacttcatcattggcatgggtttccagtat
gttgcggaggctatggggccctacgtcttccttctatttgcggtcctcctgctgggcttc
ttcatcttcaccttcttaagagtacctgaaactcgaggccggacgtttgaccagatctca
gctgccttccaccggacaccctctcttttagagcaggaggtgaaacccagcacagaactt
gagtatttagggccagatgagaacgactga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (7)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (10)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (23)   
   RefSeq(nuc) (1)   
   GenBank (11)   
   EMBL (11)   
3D Structure (2)   
   PDB (2)   
Protein domain (2)   
   Pfam (2)   
All databases (51)   

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