KEGG   Homo sapiens (human): 6812
Entry
6812              CDS       T01001                                 
Symbol
STXBP1, DEE4, MUNC18-1, N-Sec1, NSEC1, P67, RBSEC1, UNC18, unc-18A, unc18-1
Name
(RefSeq) syntaxin binding protein 1
  KO
K15292  syntaxin-binding protein 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04721  Synaptic vesicle cycle
Disease
H00606  Early infantile epileptic encephalopathy
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09156 Nervous system
   04721 Synaptic vesicle cycle
    6812 (STXBP1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    6812 (STXBP1)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    6812 (STXBP1)
Membrane trafficking [BR:hsa04131]
 Exocytosis
  Small GTPases and associated proteins
   Rab associated proteins
    6812 (STXBP1)
 SNARE
  SNARE associated proteins
   Syntaxin-binding proteins
    6812 (STXBP1)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   6812 (STXBP1)
SSDB
Motif
Pfam: Sec1 SGT1 YlbD_coat FRB_dom
Other DBs
NCBI-GeneID: 6812
NCBI-ProteinID: NP_001027392
OMIM: 602926
HGNC: 11444
Ensembl: ENSG00000136854
UniProt: P61764
Structure
Position
9:127611912..127696029
AA seq 594 aa
MAPIGLKAVVGEKIMHDVIKKVKKKGEWKVLVVDQLSMRMLSSCCKMTDIMTEGITIVED
INKRREPLPSLEAVYLITPSEKSVHSLISDFKDPPTAKYRAAHVFFTDSCPDALFNELVK
SRAAKVIKTLTEINIAFLPYESQVYSLDSADSFQSFYSPHKAQMKNPILERLAEQIATLC
ATLKEYPAVRYRGEYKDNALLAQLIQDKLDAYKADDPTMGEGPDKARSQLLILDRGFDPS
SPVLHELTFQAMSYDLLPIENDVYKYETSGIGEARVKEVLLDEDDDLWIALRHKHIAEVS
QEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKHYQG
TVDKLCRVEQDLAMGTDAEGEKIKDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITE
ENLNKLIQHAQIPPEDSEIITNMAHLGVPIVTDSTLRRRSKPERKERISEQTYQLSRWTP
IIKDIMEDTIEDKLDTKHYPYISTRSSASFSTTAVSARYGHWHKNKAPGEYRSGPRLIIF
ILGGVSLNEMRCAYEVTQANGKWEVLIGSTHILTPQKLLDTLKKLNKTDEEISS
NT seq 1785 nt   +upstreamnt  +downstreamnt
atggcccccattggcctcaaagctgttgtcggagagaagattatgcatgatgtgataaag
aaggtcaagaagaagggggaatggaaggtgctggtggtggatcagttaagcatgaggatg
ctgtcctcctgctgcaagatgacagacatcatgaccgagggcataacgattgtggaagat
atcaataagcgcagagagccgctccccagcctggaggctgtgtatctcatcactccatcc
gagaagtccgtccactctctcatcagtgactttaaggacccgccgactgctaaataccgg
gctgcacacgtcttcttcactgactcttgtccagatgccctgtttaatgaactggtaaaa
tcccgagcagccaaagtcatcaaaactctgacggaaatcaatattgcatttctcccgtat
gaatcccaggtctattccttggactctgctgactctttccaaagcttctacagtccccac
aaggctcagatgaagaatcctatactggagcgcctggcagagcagatcgcgaccctttgt
gccaccctgaaggagtacccggctgtgcggtatcggggggaatacaaggacaatgccctg
ctggctcagctaatccaggacaagctcgatgcctataaagctgatgatccaacaatgggg
gagggcccagacaaggcacgctcccagctcctgatcctggatcgaggctttgaccccagc
tcccctgtgctccatgaattgacttttcaggctatgagttatgatctgctgcctatcgaa
aatgatgtatacaagtatgagaccagcggcatcggggaggcacgggtgaaggaggtgctc
ctggacgaggacgacgacctgtggatagcactgcgccacaagcacatcgcagaggtgtcc
caggaagtcacccggtctctgaaagatttttcttctagcaagagaatgaatactggagag
aagaccaccatgcgggacctgtcccagatgctgaagaagatgcctcagtaccagaaagag
ctcagcaagtactccacccacctgcaccttgctgaggactgtatgaagcattaccaaggc
accgtagacaaactctgccgagtggagcaggacctggccatgggcacagatgctgaggga
gagaagatcaaggaccctatgcgagccatcgtccccattctgctggatgccaatgtcagc
acttatgacaaaatccgcatcatccttctctacatctttttgaagaatggcatcacggag
gaaaacctgaacaaactgatccagcacgcccagatacccccggaggatagtgagatcatc
accaacatggctcacctcggcgtgcccatcgtcaccgattccacgctgcgtcgccggagc
aagccggagcggaaggaacgcatcagcgagcagacctaccagctctcacggtggactccg
attatcaaggacatcatggaggacactattgaggacaaacttgacaccaaacactaccct
tatatctctacccgttcctctgcctccttcagcaccaccgccgtcagcgcccgctatggg
cactggcataagaacaaggccccaggcgagtaccgcagtggcccccgcctcatcattttc
atccttgggggtgtgagcctgaatgagatgcgctgcgcctacgaggtgacccaggccaac
ggaaagtgggaggtgctgataggatccacacacatcctcaccccacagaaactgctggac
acactgaagaaactgaataaaacagatgaagaaataagcagttaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (14)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (12)   
DNA sequence (34)   
   RefSeq(nuc) (12)   
   GenBank (11)   
   EMBL (11)   
3D Structure (1)   
   PDB (1)   
Protein domain (4)   
   Pfam (4)   
All databases (73)   

Download RDF
DBGET integrated database retrieval system