KEGG   Homo sapiens (human): 7089
Entry
7089              CDS       T01001                                 
Symbol
TLE2, ESG, ESG2, GRG2
Name
(RefSeq) TLE family member 2, transcriptional corepressor
  KO
K04497  groucho
Organism
hsa  Homo sapiens (human)
Pathway
hsa04310  Wnt signaling pathway
hsa04330  Notch signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    7089 (TLE2)
   04330 Notch signaling pathway
    7089 (TLE2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    7089 (TLE2)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    ADF / Cofilin
     SCMC complex
      7089 (TLE2)
SSDB
Motif
Pfam: TLE_N WD40 ANAPC4_WD40 NBCH_WD40 HALZ
Other DBs
NCBI-GeneID: 7089
NCBI-ProteinID: NP_003251
OMIM: 601041
HGNC: 11838
Ensembl: ENSG00000065717
UniProt: Q04725
Position
19:complement(2997644..3047635)
AA seq 743 aa
MYPQGRHPTPLQSGQPFKFSILEICDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHY
VMYYEMSYGLNIEMHKQAEIVKRLSGICAQIIPFLTQEHQQQVLQAVERAKQVTVGELNS
LIGQQLQPLSHHAPPVPLTPRPAGLVGGSATGLLALSGALAAQAQLAAAVKEDRAGVEAE
GSRVERAPSRSASPSPPESLVEEERPSGPGGGGKQRADEKEPSGPYESDEDKSDYNLVVD
EDQPSEPPSPATTPCGKVPICIPARRDLVDSPASLASSLGSPLPRAKELILNDLPASTPA
SKSCDSSPPQDASTPGPSSASHLCQLAAKPAPSTDSVALRSPLTLSSPFTTSFSLGSHST
LNGDLSVPSSYVSLHLSPQVSSSVVYGRSPVMAFESHPHLRGSSVSSSLPSIPGGKPAYS
FHVSADGQMQPVPFPSDALVGAGIPRHARQLHTLAHGEVVCAVTISGSTQHVYTGGKGCV
KVWDVGQPGAKTPVAQLDCLNRDNYIRSCKLLPDGRSLIVGGEASTLSIWDLAAPTPRIK
AELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWDLQNQTMVRQFQGHTDGASCIDISDY
GTRLWTGGLDNTVRCWDLREGRQLQQHDFSSQIFSLGHCPNQDWLAVGMESSNVEILHVR
KPEKYQLHLHESCVLSLKFASCGRWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDI
SRNNKYIVTGSGDKKATVYEVVY
NT seq 2232 nt   +upstreamnt  +downstreamnt
atgtacccccagggaaggcacccgaccccgctccagtccggccagcccttcaagttctcg
atcttggagatctgcgaccgcatcaaagaagaattccagtttcttcaggctcaataccac
agcctcaagctagaatgtgagaagctggccagcgagaagacggaaatgcagcgacattat
gtcatgtattatgagatgtcgtacgggctcaacattgaaatgcataagcaggcggagatt
gtgaagcgtctgagcggtatctgcgctcagattatccccttcctgacccaggagcatcag
cagcaggtgctccaggccgtagaacgcgccaagcaggtcaccgtgggggagctgaacagc
ctcatcgggcagcagctccagccgctgtcccaccacgcaccccctgtgcccctcaccccc
cgcccagccgggctggtgggcggcagtgctacggggctgcttgctctgtctggagccctg
gctgcccaggctcagctggcggcggctgtcaaggaggaccgtgcgggcgtggaggccgag
gggtccagagtggagagagccccgagcaggagtgcatctccctcgccccctgagagtctc
gtggaggaggagcgaccgagtggccctggtggtggcgggaagcagagagcagatgagaag
gagccatcaggaccttatgaaagcgacgaagacaagagtgattacaatctggtggtggac
gaggaccaaccctcagagccccccagcccggctaccaccccctgcggaaaggtacccatc
tgcattcctgcccgtcgggacctggtggacagtccagcctccttggcctctagccttggc
tcaccgctgcctagagccaaggagctcatcctgaatgaccttcccgccagcactcctgcc
tccaaatcctgtgactcctccccgccccaggacgcttccacccccgggcccagctcggcc
agtcacctctgccagcttgctgccaagccagcaccttccacggacagcgtcgccctgagg
agccccctgactctgtccagtcccttcaccacgtccttcagcctgggctcccacagcact
ctcaacggagacctctccgtgcccagctcctacgtcagcctccacctgtccccccaggtc
agcagctctgtggtgtacggacgctcccccgtgatggcatttgagtctcatccccatctc
cgagggtcatccgtctcttcctccctacccagcatccctgggggaaagccggcctactcc
ttccacgtgtctgcggacgggcagatgcagccggttcccttcccctcggatgcactggta
ggcgcgggcatcccgcggcacgcccggcagctgcacacgctggcccatggcgaggtggtc
tgcgcggtcaccatcagcggctccacacagcatgtgtacacgggcggcaagggctgtgtg
aaggtgtgggacgtgggccagcctggggccaagacgcccgtggcccagctcgactgcctg
aaccgagacaactacattcgttcctgcaagttgctgccggatggccggagtctgatcgtg
ggcggtgaggccagcaccttgtccatttgggacctggcggcgcccaccccccgtatcaag
gccgagctgacttcctcagccccagcctgctacgccctggccgtcagccccgacgccaag
gtttgcttctcctgctgcagcgatggcaacattgtggtctgggacctgcagaatcagact
atggtcaggcagttccagggccacacggacggcgccagctgcattgatatttccgattac
ggcactcggctctggacagggggcctggacaacacggtgcgctgctgggacctgcgggag
ggccgccagctgcagcagcatgacttcagctcccagattttctccctgggccactgccct
aaccaggactggctggcggtcggaatggagagtagcaacgtggagatcctgcacgtccgc
aagccggagaaataccagctgcacctccacgagagctgcgtgctgtccctgaagtttgcc
tcctgcggacggtggtttgtgagcaccgggaaggacaacctgctcaacgcctggaggacg
ccgtacggggccagcattttccagtccaaggagtcgtcctcagtcctgagttgtgacatc
tccagaaataacaaatacatcgtgacaggctcgggggacaagaaggccaccgtgtatgag
gtggtctactga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (22)   
   KEGG ORTHOLOGY (1)   
   RefGene (14)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (10)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (8)   
DNA sequence (32)   
   RefSeq(nuc) (8)   
   GenBank (12)   
   EMBL (12)   
Protein domain (5)   
   Pfam (5)   
All databases (75)   

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