KEGG   Homo sapiens (human): 732
Entry
732               CDS       T01001                                 
Symbol
C8B, C82
Name
(RefSeq) complement C8 beta chain
  KO
K03998  complement component 8 subunit beta
Organism
hsa  Homo sapiens (human)
Pathway
hsa04610  Complement and coagulation cascades
hsa04810  Regulation of actin cytoskeleton
hsa05020  Prion disease
hsa05146  Amoebiasis
hsa05171  Coronavirus disease - COVID-19
hsa05322  Systemic lupus erythematosus
Network
nt06513  Complement cascade
  Element
N01490  Common pathway of complement cascade, MAC formation
N01505  Regulation of complement cascade, MAC inhibition
Disease
H00103  Late complement pathway defects
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    732 (C8B)
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    732 (C8B)
 09160 Human Diseases
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    732 (C8B)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    732 (C8B)
  09163 Immune disease
   05322 Systemic lupus erythematosus
    732 (C8B)
  09164 Neurodegenerative disease
   05020 Prion disease
    732 (C8B)
SSDB
Motif
Pfam: MACPF C8A_B_C6_EGF-like Ldl_recept_a TSP_1 TSP1_spondin
Other DBs
NCBI-GeneID: 732
NCBI-ProteinID: NP_000057
OMIM: 120960
HGNC: 1353
Ensembl: ENSG00000021852
UniProt: P07358
Structure
Position
1:complement(56929207..56966015)
AA seq 591 aa
MKNSRTWAWRAPVELFLLCAALGCLSLPGSRGERPHSFGSNAVNKSFAKSRQMRSVDVTL
MPIDCELSSWSSWTTCDPCQKKRYRYAYLLQPSQFHGEPCNFSDKEVEDCVTNRPCGSQV
RCEGFVCAQTGRCVNRRLLCNGDNDCGDQSDEANCRRIYKKCQHEMDQYWGIGSLASGIN
LFTNSFEGPVLDHRYYAGGCSPHYILNTRFRKPYNVESYTPQTQGKYEFILKEYESYSDF
ERNVTEKMASKSGFSFGFKIPGIFELGISSQSDRGKHYIRRTKRFSHTKSVFLHARSDLE
VAHYKLKPRSLMLHYEFLQRVKRLPLEYSYGEYRDLFRDFGTHYITEAVLGGIYEYTLVM
NKEAMERGDYTLNNVHACAKNDFKIGGAIEEVYVSLGVSVGKCRGILNEIKDRNKRDTMV
EDLVVLVRGGASEHITTLAYQELPTADLMQEWGDAVQYNPAIIKVKVEPLYELVTATDFA
YSSTVRQNMKQALEEFQKEVSSCHCAPCQGNGVPVLKGSRCDCICPVGSQGLACEVSYRK
NTPIDGKWNCWSNWSSCSGRRKTRQRQCNNPPPQNGGSPCSGPASETLDCS
NT seq 1776 nt   +upstreamnt  +downstreamnt
atgaagaattccaggacatgggcttggagggcgccggtggagctatttcttctctgtgct
gccctgggctgtctcagtttgcctggctccagaggtgaaaggccacattcctttgggtca
aatgcagtcaacaagagctttgctaagagcagacagatgcggagtgtggatgttaccctg
atgcccattgattgtgagctgtctagttggtcctcttggaccacatgtgacccctgtcag
aagaaaaggtacaggtatgcctacttgctccagccctctcagttccatggggaaccgtgc
aacttctctgacaaggaagtcgaagactgtgttaccaacagaccatgcggaagtcaagtg
cgatgtgaaggctttgtgtgtgcacagacaggaaggtgtgtaaaccgcagacttctttgc
aatggggacaatgactgtggagaccagtcagatgaagcaaactgtagaaggatttataaa
aaatgtcagcatgaaatggaccaatactggggaattggcagtctggccagtgggataaat
ttgttcacaaacagttttgagggcccagttcttgatcacaggtattatgcaggtggatgc
tccccgcattacatcctgaacacgaggtttaggaagccctacaatgtggaaagctacacg
ccacagacccaaggcaaatacgaattcatattaaaagagtatgaatcatactcagatttt
gaacgcaatgtcacagagaaaatggcaagcaagtctggtttcagttttggttttaaaata
cctggaatatttgaacttggcatcagtagtcaaagtgatcgaggcaaacactatattagg
agaaccaaacgattctctcatactaaaagcgtatttctgcatgcacgctctgaccttgaa
gtagcacattacaagctgaaacccagaagcctcatgctccattacgagttccttcagaga
gttaagcggctgcccctggagtacagctacggggaatacagagatctcttccgtgatttt
gggacccactacatcacagaggctgtgcttgggggcatttatgaatacaccctcgttatg
aacaaagaggccatggagagaggagattatactcttaacaacgtccatgcctgtgccaaa
aatgattttaaaattggtggtgccattgaagaggtctacgtcagtctgggtgtgtctgta
ggcaaatgcagaggtattctgaatgaaataaaagacagaaacaagagggacaccatggtg
gaggacttggtggtcctggtacgaggaggggcaagtgagcacatcaccaccctggcatac
caggagctgccgacggcggacctgatgcaggagtggggagacgctgtgcagtacaaccca
gccatcatcaaagttaaggtggagcctctgtatgaactagtgacagccacagattttgcc
tattccagcacagtgaggcagaacatgaagcaggcactggaggagttccagaaggaagtt
agttcctgccactgtgctccctgccaaggaaatggagtccctgtcctgaaaggatcacgc
tgtgactgcatctgtcctgttggatcccaaggcctagcctgtgaggtctcctatcggaag
aatacccccattgatgggaagtggaattgctggtcaaattggtcttcatgctctggaaga
cgtaagacaagacaaaggcagtgtaacaatccacctcctcaaaatgggggtagcccctgt
tcaggccctgcttcagaaacacttgactgctcctag

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (6)   
   KEGG PATHWAY (6)   
Network (3)   
   KEGG NETWORK (3)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   RefGene (12)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (7)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (25)   
   RefSeq(nuc) (5)   
   GenBank (10)   
   EMBL (10)   
3D Structure (8)   
   PDB (8)   
Protein domain (5)   
   Pfam (5)   
All databases (77)   

Download RDF
DBGET integrated database retrieval system