KEGG   PATHWAY: hsa03020Help
Entry
hsa03020                    Pathway                                

Name
RNA polymerase - Homo sapiens (human)
Class
Genetic Information Processing; Transcription
BRITE hierarchy
Pathway map
hsa03020  RNA polymerase
hsa03020

Ortholog table
Module
hsa_M00180  RNA polymerase II, eukaryotes [PATH:hsa03020]
hsa_M00181  RNA polymerase III, eukaryotes [PATH:hsa03020]
hsa_M00182  RNA polymerase I, eukaryotes [PATH:hsa03020]
Disease
H00610  Treacher Collins syndrome
Other DBs
BSID: 83037
GO: 0000428
Organism
Homo sapiens (human) [GN:hsa]
Gene
5431  POLR2B; RNA polymerase II subunit B [KO:K03010] [EC:2.7.7.6]
5430  POLR2A; RNA polymerase II subunit A [KO:K03006] [EC:2.7.7.6]
5432  POLR2C; RNA polymerase II subunit C [KO:K03011]
5439  POLR2J; RNA polymerase II subunit J [KO:K03008]
548644  POLR2J3; RNA polymerase II subunit J3 [KO:K03008]
246721  POLR2J2; RNA polymerase II subunit J2 [KO:K03008]
5433  POLR2D; RNA polymerase II subunit D [KO:K03012]
5436  POLR2G; RNA polymerase II subunit G [KO:K03015]
5438  POLR2I; RNA polymerase II subunit I [KO:K03017]
5434  POLR2E; RNA polymerase II subunit E [KO:K03013]
5435  POLR2F; RNA polymerase II subunit F [KO:K03014]
5437  POLR2H; RNA polymerase II subunit H [KO:K03016]
5440  POLR2K; RNA polymerase II subunit K [KO:K03009]
5441  POLR2L; RNA polymerase II subunit L [KO:K03007]
55703  POLR3B; RNA polymerase III subunit B [KO:K03021] [EC:2.7.7.6]
11128  POLR3A; RNA polymerase III subunit A [KO:K03018] [EC:2.7.7.6]
51082  POLR1D; RNA polymerase I and III subunit D [KO:K03020]
9533  POLR1C; RNA polymerase I and III subunit C [KO:K03027]
10623  POLR3C; RNA polymerase III subunit C [KO:K03023]
661  POLR3D; RNA polymerase III subunit D [KO:K03026]
55718  POLR3E; RNA polymerase III subunit E [KO:K14721]
51728  POLR3K; RNA polymerase III subunit K [KO:K03019]
171568  POLR3H; RNA polymerase III subunit H [KO:K03022]
84265  POLR3GL; RNA polymerase III subunit G like [KO:K03024]
10622  POLR3G; RNA polymerase III subunit G [KO:K03024]
10621  POLR3F; RNA polymerase III subunit F [KO:K03025]
84172  POLR1B; RNA polymerase I subunit B [KO:K03002] [EC:2.7.7.6]
25885  POLR1A; RNA polymerase I subunit A [KO:K02999] [EC:2.7.7.6]
30834  ZNRD1; zinc ribbon domain containing 1 [KO:K03000]
64425  POLR1E; RNA polymerase I subunit E [KO:K03005]
221830  TWISTNB; TWIST neighbor [KO:K03004]
Reference
  Authors
Zhang G, Campbell EA, Minakhin L, Richter C, Severinov K, Darst SA.
  Title
Crystal structure of Thermus aquaticus core RNA polymerase at 3.3 A resolution.
  Journal
Cell 98:811-824 (1999)
DOI:10.1016/S0092-8674(00)81515-9
Reference
  Authors
Cramer P, Bushnell DA, Fu J, Gnatt AL, Maier-Davis B, Thompson NE, Burgess RR, Edwards AM, David PR, Kornberg RD.
  Title
Architecture of RNA polymerase II and implications for the transcription mechanism.
  Journal
Science 288:640-649 (2000)
DOI:10.1126/science.288.5466.640
Reference
  Authors
Hirata A, Murakami KS
  Title
Archaeal RNA polymerase.
  Journal
Curr Opin Struct Biol 19:724-31 (2009)
DOI:10.1016/j.sbi.2009.10.006
Reference
  Authors
Cramer P, Armache KJ, Baumli S, Benkert S, Brueckner F, Buchen C, Damsma GE, Dengl S, Geiger SR, Jasiak AJ, Jawhari A, Jennebach S, Kamenski T, Kettenberger H, Kuhn CD, Lehmann E, Leike K, Sydow JF, Vannini A
  Title
Structure of eukaryotic RNA polymerases.
  Journal
Annu Rev Biophys 37:337-52 (2008)
DOI:10.1146/annurev.biophys.37.032807.130008
KO pathway
ko03020   

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