KEGG   Homo sapiens (human): 10
Entry
10                CDS       T01001                                 
Symbol
NAT2, AAC2, NAT-2, PNAT
Name
(RefSeq) N-acetyltransferase 2
  KO
K00622  arylamine N-acetyltransferase [EC:2.3.1.5]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00232  Caffeine metabolism
hsa00983  Drug metabolism - other enzymes
hsa01100  Metabolic pathways
hsa05204  Chemical carcinogenesis - DNA adducts
Network
nt06250  DNA adduct formation (cancer)
  Element
N01370  PhIP to DNA adducts
N01372  IQ to DNA adducts
N01373  MeIQx to DNA adducts
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00232 Caffeine metabolism
    10 (NAT2)
  09111 Xenobiotics biodegradation and metabolism
   00983 Drug metabolism - other enzymes
    10 (NAT2)
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis - DNA adducts
    10 (NAT2)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.5  arylamine N-acetyltransferase
     10 (NAT2)
SSDB
Motif
Pfam: Acetyltransf_2
Other DBs
NCBI-GeneID: 10
NCBI-ProteinID: NP_000006
OMIM: 612182
HGNC: 7646
Ensembl: ENSG00000156006
UniProt: P11245 A4Z6T7
Structure
Position
8:18386301..18401218
AA seq 290 aa
MDIEAYFERIGYKNSRNKLDLETLTDILEHQIRAVPFENLNMHCGQAMELGLEAIFDHIV
RRNRGGWCLQVNQLLYWALTTIGFQTTMLGGYFYIPPVNKYSTGMVHLLLQVTIDGRNYI
VDAGSGSSSQMWQPLELISGKDQPQVPCIFCLTEERGIWYLDQIRREQYITNKEFLNSHL
LPKKKHQKIYLFTLEPRTIEDFESMNTYLQTSPTSSFITTSFCSLQTPEGVYCLVGFILT
YRKFNYKDNTDLVEFKTLTEEEVEEVLRNIFKISLGRNLVPKPGDGSLTI
NT seq 873 nt   +upstreamnt  +downstreamnt
atggacattgaagcatattttgaaagaattggctataagaactctaggaacaaattggac
ttggaaacattaactgacattcttgagcaccagatccgggctgttccctttgagaacctt
aacatgcattgtgggcaagccatggagttgggcttagaggctatttttgatcacattgta
agaagaaaccggggtgggtggtgtctccaggtcaatcaacttctgtactgggctctgacc
acaatcggttttcagaccacaatgttaggagggtatttttacatccctccagttaacaaa
tacagcactggcatggttcaccttctcctgcaggtgaccattgacggcaggaattacatt
gtcgatgctgggtctggaagctcctcccagatgtggcagcctctagaattaatttctggg
aaggatcagcctcaggtgccttgcattttctgcttgacagaagagagaggaatctggtac
ctggaccaaatcaggagagagcagtatattacaaacaaagaatttcttaattctcatctc
ctgccaaagaagaaacaccaaaaaatatacttatttacgcttgaacctcgaacaattgaa
gattttgagtctatgaatacatacctgcagacgtctccaacatcttcatttataaccaca
tcattttgttccttgcagaccccagaaggggtttactgtttggtgggcttcatcctcacc
tatagaaaattcaattataaagacaatacagatctggtcgagtttaaaactctcactgag
gaagaggttgaagaagtgctgagaaatatatttaagatttccttggggagaaatctcgtg
cccaaacctggtgatggatcccttactatttag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Network (4)   
   KEGG NETWORK (4)   
Disease (2)   
   OMIM (2)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (6)   
   KEGG ENZYME (1)   
   KEGG REACTION (5)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   NAGAHAMA-S (1)   
   OC (1)   
Protein sequence (6)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (23)   
   RefSeq(nuc) (3)   
   GenBank (10)   
   EMBL (10)   
3D Structure (1)   
   PDB (1)   
Protein domain (1)   
   Pfam (1)   
All databases (74)   

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