KEGG   Homo sapiens (human): 10010
Entry
10010             CDS       T01001                                 
Symbol
TANK, I-TRAF, ITRAF, TRAF2
Name
(RefSeq) TRAF family member associated NFKB activator
  KO
K12650  TRAF family member-associated NF-kappa-B activator
Organism
hsa  Homo sapiens (human)
Pathway
hsa04140  Autophagy - animal
hsa04621  NOD-like receptor signaling pathway
hsa04622  RIG-I-like receptor signaling pathway
hsa05014  Amyotrophic lateral sclerosis
hsa05022  Pathways of neurodegeneration - multiple diseases
hsa05417  Lipid and atherosclerosis
Network
nt06162  Hepatitis B virus (HBV)
nt06163  Hepatitis C virus (HCV)
nt06165  Epstein-Barr virus (EBV)
nt06168  Herpes simplex virus 1 (HSV-1)
nt06169  Measles virus (MV)
nt06170  Influenza A virus (IAV)
nt06171  SARS coronavirus 2 (SARS-CoV-2)
nt06263  Hepatocellular carcinoma
nt06519  RLR signaling
  Element
N00469  RIG-I-IRF7/3 signaling pathway
N01308  MDA5-IRF7/3 signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    10010 (TANK)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    10010 (TANK)
   04622 RIG-I-like receptor signaling pathway
    10010 (TANK)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    10010 (TANK)
   05022 Pathways of neurodegeneration - multiple diseases
    10010 (TANK)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    10010 (TANK)
SSDB
Motif
Pfam: TBD PspA_IM30 FliD_N MYRF_ICA AAA_13
Other DBs
NCBI-GeneID: 10010
NCBI-ProteinID: NP_001186064
OMIM: 603893
HGNC: 11562
Ensembl: ENSG00000136560
UniProt: Q92844 B2R7S3 Q6NW12
Structure
Position
2:161136963..161236230
AA seq 425 aa
MDKNIGEQLNKAYEAFRQACMDRDSAVKELQQKTENYEQRIREQQEQLSLQQTIIDKLKS
QLLLVNSTQDNNYGCVPLLEDSETRKNNLTLDQPQDKVISGIAREKLPKVRRQEVSSPRK
ETSARSLGSPLLHERGNIEKTFWDLKEEFHKICMLAKAQKDHLSKLNIPDTATETQCSVP
IQCTDKTDKQEALFKPQAKDDINRGAPSITSVTPRGLCRDEEDTSFESLSKFNVKFPPMD
NDSTFLHSTPERPGILSPATSEAVCQEKFNMEFRDNPGNFVKTEETLFEIQGIDPIASAI
QNLKTTDKTKPSNLVNTCIRTTLDRAACLPPGDHNALYVNSFPLLDPSDAPFPSLDSPGK
AIRGPQQPIWKPFPNQDSDSVVLSGTDSELHIPRVCEFCQAVFPPSITSRGDFLRHLNSH
FNGET
NT seq 1278 nt   +upstreamnt  +downstreamnt
atggataaaaacattggcgagcaactcaataaagcgtatgaagccttccggcaggcatgc
atggatagagattctgcagtaaaagaattacagcaaaagactgagaactatgagcagaga
atacgtgaacaacaggaacagctgtcacttcaacagactattattgacaagctaaaatct
cagttacttcttgtgaattccactcaagataacaattatggctgtgttcctctgcttgaa
gacagtgaaacaagaaagaataatttgactcttgatcagccacaagataaagtgatttca
ggaatagcaagagaaaaactaccaaaggtaagaagacaagaggtttcttctcctagaaaa
gaaacttcagcaaggagtcttggcagtcctttgctccatgaaaggggtaatatagagaag
actttctgggatctgaaagaagaatttcataaaatatgcatgctagcaaaagcacagaaa
gaccacttaagcaaacttaatataccagacactgcaactgaaacacagtgctctgtgcct
atacagtgtacggataaaacagataaacaagaagcgctgtttaagcctcaggctaaagat
gatataaatagaggtgcaccatccatcacatctgtcacaccaagaggactgtgcagagat
gaggaagacacctcttttgaatcactttctaaattcaatgtcaagtttccacctatggac
aatgactcaactttcttacatagcactccagagagacccggcatccttagtcctgccacg
tctgaggcagtgtgccaagagaaatttaatatggagttcagagacaacccagggaacttt
gttaaaacagaagaaactttatttgaaattcagggaattgaccccatagcttcagctata
caaaaccttaaaacaactgacaaaacaaagccctcaaatctcgtaaacacttgtatcagg
acaactctggatagagctgcgtgtttgccacctggagaccataatgcattatatgtaaat
agcttcccacttctggacccatctgatgcaccttttccctcactcgattccccgggaaaa
gcaatccgaggaccacagcagcccatttggaagccctttcctaatcaagacagtgactcg
gtggtactaagtggcacagactcagaactgcatatacctcgagtatgtgaattctgtcaa
gcagttttcccaccatccattacatccaggggggatttccttcggcatcttaattcacac
ttcaatggagagacttaa

  All links  
Disease (1)   
   OMIM (1)   
Gene (16)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
Protein sequence (28)   
   UniProt (3)   
   SWISS-PROT (1)   
   RefSeq(pep) (24)   
DNA sequence (36)   
   RefSeq(nuc) (24)   
   GenBank (6)   
   EMBL (6)   
3D Structure (3)   
   PDB (3)   
Protein domain (5)   
   Pfam (5)   
All databases (89)   

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