KEGG   Homo sapiens (human): 100271927Help
Entry
100271927         CDS       T01001                                 

Gene name
RASA4B
Definition
(RefSeq) RAS p21 protein activator 4B
  KO
K17630  Ras GTPase-activating protein 4
Organism
hsa  Homo sapiens (human)
Pathway
hsa04014  Ras signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    100271927 (RASA4B)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: C2 RasGAP BTK
Motif
Other DBs
NCBI-GeneID: 100271927
NCBI-ProteinID: NP_001264264
HGNC: 35202
Ensembl: ENSG00000170667
Vega: OTTHUMG00000022944
UniProt: F5GXT2
Position
7q22.1
AA seq 757 aa AA seqDB search
MAKRSSLYIRIVEGKNLPAKDITGSSDPYCIVKVDNEPIIRTATVWKTLCPFWGEEYQVH
LPPTFHAVAFYVMDEDALSRDDVIGKVCLTRDTIASHPKGFSGWAHLTEVDPDEEVQGEI
HLRLEVWPGARACRLRCSVLEARDLAPKDRNGTSDPFVRVRYKGRTRETSIVKKSCYPRW
NETFEFELQEGAMEALCVEAWDWDLVSRNDFLGKVVIDVQRLRVVQQEEGWFRLQPDQSK
SRRHDEGNLGSLQLEVRLRDETVLPSSYYQPLVHLLCHEVKLGMQGPGQLIPLIEETTST
ECRQDVATNLLKLFLGQGLAKDFLDLLFQLELSRTSETNTLFRSNSLASKSVESFLKVAG
MQYLHGVLGPIINKVFEEKKYVELDPSKVEVKDVGCSGLHRPQTEAEVLEQSAQTLRAHL
GALLSALSRSVRACPAVVRATFRQLFRRVRERFPGAQHENVPFIAVTSFLCLRFFSPAIM
SPKLFHLRERHADARTSRTLLLLAKAVQNVGNMDTPASRAKEAWMEPLQPTVHQGVAQLK
DFITKLVDIEEKDELDLQRTLSLQAPPVKEGPLFIHRTKGKGPLMSSSFKKLYFSLTTEA
LSFAKTPSSKCVNELNQWLSALRKVSINNTGLLGSYHPGVFRGDKWSCCHQKEKTGQGCD
KTRSRVTLQEWNDPLDHDLEAQLIYRHLLGVEAMLWERHRELSGGAEAGTVPTSPGKVPE
DSLARLLRVLQDLREAHSSSPAGSPPSEPNCLLELQT
NT seq 2274 nt NT seq  +upstreamnt  +downstreamnt
atggccaagcgcagctcgctgtacatccgcatcgtggaggggaagaaccttcccgccaag
gacatcactggcagcagcgacccctactgcatcgtgaaggtggacaatgagcccatcatc
aggacagccacagtgtggaagaccctgtgccccttctggggtgaggagtaccaagtgcac
ctgccgcccaccttccacgctgtggctttctatgtcatggatgaggatgccctcagccgg
gacgacgttatcggaaaggtctgccttacaagggacaccatagcctctcaccctaagggt
ttcagcgggtgggcccacctgacagaggtcgaccccgacgaggaggtgcagggcgagatc
cacctgcggctggaagtgtggccaggggcccgggcctgccggctacgctgctctgtgctg
gaggccagggatctggccccaaaggaccgcaatggcacatctgaccccttcgtccgagtg
cgctacaagggccggacacgggagacctcgatcgtgaagaagtcatgctacccacgctgg
aatgagacgtttgaatttgagctgcaggagggggccatggaggcgctgtgcgtggaggcc
tgggactgggaccttgtcagccgaaacgacttcctgggcaaagtggtgattgatgtccag
agactgcgggtggtgcagcaggaggagggctggttccggctgcagcccgaccagtccaag
agccggcggcatgacgagggcaacctgggctccttgcagctggaggtgcggctgcgggac
gagacggtgctgccctccagctactaccagccactggtgcacctgctgtgccacgaggtc
aagctgggcatgcagggcccagggcagctgatcccactcatcgaggagacaaccagcacc
gagtgtcgccaggacgtggccacgaacctgctcaagctcttcctggggcaggggctggcc
aaggacttcctggacctgctcttccagctggagctgagtcgcaccagtgagaccaacacc
ctgttccggagcaactctctggcctcaaagtccgtggagtcttttctgaaggtggccggg
atgcagtacctgcacggcgtcctgggccccatcatcaacaaggtgtttgaggagaagaag
tacgtggagctggaccccagcaaagtggaagttaaggatgtagggtgctccgggctgcac
cgcccgcagaccgaggccgaggtgctggagcagagcgcgcagacgctgcgcgcccacctg
ggggccctgctgagcgcgctcagccgctcggttcgcgcgtgccccgccgtggtgcgcgcc
accttccgccagctcttccggcgcgtgcgcgagcgcttccccggcgcccagcacgagaat
gtaccgttcatcgccgtcaccagcttcctgtgcctgcgcttcttctctcccgccatcatg
tcgcccaagctcttccacctgcgggagcgccacgcggacgcccgcaccagccgcaccctg
ctcctgttggccaaggcagtccagaacgtgggcaacatggacacgccggcttccagggcc
aaggaggcttggatggagccgctgcagcccaccgtgcaccagggcgtggcgcagctgaag
gacttcatcaccaagctcgtggacatcgaggagaaggacgagctggacctgcagcggacg
ctgagtttgcaggcgccacctgtgaaggaggggccactcttcatccacaggaccaagggc
aagggccccctcatgtcctcctccttcaagaagctctacttctccctcactaccgaggcc
ctcagcttcgcgaagacgcccagctccaagtgtgtgaatgagcttaaccagtggctgtct
gcgctgcggaaggtgagcatcaacaacaccggactgctgggctcctaccaccctggcgtc
ttccgtggggacaagtggagctgctgccaccaaaaagagaagacaggtcagggctgcgat
aagacccggtcacgggtgaccctgcaggagtggaatgaccctcttgaccatgaccttgag
gcccagctcatctaccggcacctgctgggcgtggaggccatgctgtgggagaggcaccgg
gagctgagcgggggcgcagaggcaggcacggtgcccacgagccctggcaaagtccccgag
gactcattggcccggctgctccgggtgctgcaggacctccgcgaggcccatagctccagc
ccggccggctccccaccctcagagcccaactgcctcctggagctgcagacgtga

KEGG   Homo sapiens (human): 10156Help
Entry
10156             CDS       T01001                                 

Gene name
RASA4, CAPRI, GAPL
Definition
(RefSeq) RAS p21 protein activator 4
  KO
K17630  Ras GTPase-activating protein 4
Organism
hsa  Homo sapiens (human)
Pathway
hsa04014  Ras signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    10156 (RASA4)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: C2 RasGAP BTK PH
Motif
Other DBs
NCBI-GeneID: 10156
NCBI-ProteinID: NP_008920
OMIM: 607943
HGNC: 23181
Ensembl: ENSG00000105808
Vega: OTTHUMG00000150383
Pharos: O43374(Tbio)
UniProt: O43374
Position
7q22.1
AA seq 803 aa AA seqDB search
MAKRSSLYIRIVEGKNLPAKDITGSSDPYCIVKVDNEPIIRTATVWKTLCPFWGEEYQVH
LPPTFHAVAFYVMDEDALSRDDVIGKVCLTRDTIASHPKGFSGWAHLTEVDPDEEVQGEI
HLRLEVWPGARACRLRCSVLEARDLAPKDRNGTSDPFVRVRYKGRTRETSIVKKSCYPRW
NETFEFELQEGAMEALCVEAWDWDLVSRNDFLGKVVIDVQRLRVVQQEEGWFRLQPDQSK
SRRHDEGNLGSLQLEVRLRDETVLPSSYYQPLVHLLCHEVKLGMQGPGQLIPLIEETTST
ECRQDVATNLLKLFLGQGLAKDFLDLLFQLELSRTSETNTLFRSNSLASKSMESFLKVAG
MQYLHGVLGPIINKVFEEKKYVELDPSKVEVKDVGCSGLHRPQTEAEVLEQSAQTLRAHL
GALLSALSRSVRACPAVVRATFRQLFRRVRERFPGAQHENVPFIAVTSFLCLRFFSPAIM
SPKLFHLRERHADARTSRTLLLLAKAVQNVGNMDTPASRAKEAWMEPLQPTVRQGVAQLK
DFITKLVDIEEKDELDLQRTLSLQAPPVKEGPLFIHRTKGKGPLMSSSFKKLYFSLTTEA
LSFAKTPSSKKSALIKLANIRAAEKVEEKSFGGSHVMQVIYTDDAGRPQTAYLQCKCVNE
LNQWLSALRKVSINNTGLLGSYHPGVFRGDKWSCCHQKEKTGQGCDKTRSRVTLQEWNDP
LDHDLEAQLIYRHLLGVEAMLWERHRELSGGAEAGTVPTSPGKVPEDSLARLLRVLQDLR
EAHSSSPAGSPPSEPNCLLELQT
NT seq 2412 nt NT seq  +upstreamnt  +downstreamnt
atggccaagcgcagctcgctgtacatccgcatcgtggaggggaagaaccttcccgccaag
gacatcactggcagcagcgacccctactgcatcgtgaaggtggacaatgagcccatcatc
aggacagccacagtgtggaagaccctgtgccccttctggggtgaggagtaccaagtgcac
ctgccgcccaccttccacgctgtggctttctatgtcatggatgaggatgccctcagccgg
gacgacgttatcggaaaggtctgccttacaagggacaccatagcctctcaccctaagggt
ttcagcgggtgggcccacctgacggaggtcgaccccgatgaggaggtgcagggcgagatc
cacctgcggctggaagtgtggccaggggcccgggcctgccggctacgctgctctgtgctg
gaggccagggatctggccccaaaggaccgcaatggcacatctgaccccttcgtccgagtg
cgctacaagggccggacacgggagacctcgatcgtgaagaagtcatgctacccacgctgg
aatgagacgtttgaatttgagctgcaggagggggccatggaggcgctgtgcgtggaggcc
tgggactgggaccttgtcagccgaaacgacttcctgggcaaagtggtgattgatgtccag
agactgcgggtggtgcagcaggaggagggctggttccggctgcagcccgaccagtccaag
agccggcggcatgacgagggcaacctgggctccttgcagctggaggtgcggctgcgggac
gagacggtgctgccctccagctactaccagccactggtgcacctgctgtgccacgaggtc
aagctgggcatgcagggcccagggcagctgatcccactcatcgaggagacaaccagcacc
gagtgtcgccaggacgtggccacgaacctgctcaagctcttcctggggcaggggctggcc
aaggacttcctggacctgctcttccagctggagctgagtcgcaccagtgagaccaacacc
ctgttccggagcaactctctggcctcaaagtccatggagtcttttctgaaggtggccggg
atgcagtacctgcacggcgtcctgggccccatcatcaacaaggtgtttgaggagaagaag
tacgtggagctggaccccagcaaagtggaagttaaggatgtagggtgctccgggctgcac
cgcccgcagaccgaggccgaggtgctggagcagagcgcgcagacgctgcgcgcccacctg
ggggccctgctgagcgcgctcagccgctcggttcgcgcgtgccccgccgtggtgcgcgcc
accttccgccagctcttccggcgcgtgcgcgagcgcttccccggcgcccagcacgagaat
gtaccgttcatcgccgtcaccagcttcctgtgcctgcgcttcttctctcccgccatcatg
tcgcccaagctcttccacctgcgggagcgccacgcggacgcccgcaccagccgcaccctg
ctcctgttggccaaggcagtccagaacgtgggcaacatggacacgccggcttccagggcc
aaggaggcttggatggagccgctgcagcccaccgtgcgccagggcgtggcgcagctgaag
gacttcatcaccaagctcgtggacatcgaggagaaggacgagctggacctgcagcggacg
ctgagtttgcaggcgccacctgtgaaggaggggccactcttcatccacaggaccaagggc
aagggccccctcatgtcctcctccttcaagaagctctacttctccctcactaccgaggcc
ctcagcttcgcgaagacgcccagctccaagaaaagcgccctcatcaagttagccaacatc
cgggcagcggaaaaggttgaggaaaagagctttggcggctcgcacgtcatgcaggtcatc
tacacggacgacgccggcaggccccagactgcctacctgcagtgcaagtgtgtgaatgag
cttaaccagtggctgtctgcgctgcggaaggtgagcatcaacaacaccggactgctgggc
tcctaccaccctggcgtcttccgtggggacaagtggagctgctgccaccaaaaagagaag
acaggtcagggctgcgataagacccggtcacgggtgaccctgcaggagtggaatgaccct
cttgaccatgaccttgaggcccagctcatctaccggcacctgctgggcgtggaggccatg
ctgtgggagaggcaccgggagctgagcgggggcgcagaggcaggcacggtgcccacgagc
cctggcaaagtccccgaggactcattggcccggctgctccgggtgctgcaggacctccgc
gaggcccatagctccagcccggccggctccccaccctcagagcccaactgcctcctggag
ctgcagacgtga

KEGG   Homo sapiens (human): 22821Help
Entry
22821             CDS       T01001                                 

Gene name
RASA3, GAP1IP4BP, GAPIII
Definition
(RefSeq) RAS p21 protein activator 3
  KO
K12380  Ras GTPase-activating protein 3
Organism
hsa  Homo sapiens (human)
Pathway
hsa04014  Ras signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    22821 (RASA3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: C2 RasGAP PH BTK PH_8
Motif
Other DBs
NCBI-GeneID: 22821
NCBI-ProteinID: NP_031394
OMIM: 605182
HGNC: 20331
Ensembl: ENSG00000185989
Vega: OTTHUMG00000017399
Pharos: Q14644(Tbio)
UniProt: Q14644
Position
13q34
AA seq 834 aa AA seqDB search
MAVEDEGLRVFQSVKIKIGEAKNLPSYPGPSKMRDCYCTVNLDQEEVFRTKIVEKSLCPF
YGEDFYCEIPRSFRHLSFYIFDRDVFRRDSIIGKVAIQKEDLQKYHNRDTWFQLQHVDAD
SEVQGKVHLELRLSEVITDTGVVCHKLATRIVECQGLPIVNGQCDPYATVTLAGPFRSEA
KKTKVKRKTNNPQFDEVFYFEVTRPCSYSKKSHFDFEEEDVDKLEIRVDLWNASNLKFGD
EFLGELRIPLKVLRQSSSYEAWYFLQPRDNGSKSLKPDDLGSLRLNVVYTEDHVFSSDYY
SPLRDLLLKSADVEPVSASAAHILGEVCREKQEAAVPLVRLFLHYGRVVPFISAIASAEV
KRTQDPNTIFRGNSLASKCIDETMKLAGMHYLHVTLKPAIEEICQSHKPCEIDPVKLKDG
ENLENNMENLRQYVDRVFHAITESGVSCPTVMCDIFFSLREAAAKRFQDDPDVRYTAVSS
FIFLRFFAPAILSPNLFQLTPHHTDPQTSRTLTLISKTVQTLGSLSKSKSASFKESYMAT
FYEFFNEQKYADAVKNFLDLISSSGRRDPKSVEQPIVLKEGFMIKRAQGRKRFGMKNFKK
RWFRLTNHEFTYHKSKGDQPLYSIPIENILAVEKLEEESFKMKNMFQVIQPERALYIQAN
NCVEAKDWIDILTKVSQCNQKRLTVYHPSAYLSGHWLCCRAPSDSAPGCSPCTGGLPANI
QLDIDGDRETERIYSLFNLYMSKLEKMQEACGSKSVYDGPEQEEYSTFVIDDPQETYKTL
KQVIAGVGALEQEHAQYKRDKFKKTKYGSQEHPIGDKSFQNYIRQQSETSTHSI
NT seq 2505 nt NT seq  +upstreamnt  +downstreamnt
atggcggtggaggacgaggggctccgggtcttccagagcgtgaagatcaagatcggtgaa
gccaaaaaccttccctcttacccggggccgagcaagatgagggattgctactgcacggtg
aacctggaccaggaggaggttttcaggaccaaaattgtggaaaagtcactctgcccgttt
tacggagaagacttttactgtgaaattcctcggagctttcgtcacctgtccttctacatt
ttcgatagagacgttttccggagggattccatcatagggaaggtggccatccagaaggag
gacttgcagaagtaccacaacagggacacctggttccagctgcagcacgtggacgctgac
tcggaagtgcagggcaaagtgcacctggagctgcggctgagcgaggtcatcacagacact
ggggtcgtctgccacaagctcgccacacgcatcgtcgagtgccagggcctccccatcgtg
aatgggcaatgtgacccctacgccaccgtgacgctggcaggacccttcagatcagaagca
aagaagacgaaagtgaagaggaagaccaacaatccccagttcgatgaagtgttttatttt
gaggtgacccggccctgtagctacagcaagaagtcccactttgactttgaggaggaagac
gtggacaagctcgaaatcagagttgacctctggaatgccagtaacctgaagtttggagat
gaattcctgggagaactaaggatcccgttgaaagtcctgcggcagtccagctcctacgag
gcgtggtacttcctccagccccgggacaatggtagcaagagcctaaagccagacgacctg
ggctccctgcggctgaacgtggtatacacggaagaccacgtgttttcttctgactattac
agccctctgcgggacctgctgttgaagtctgcggatgtggagcccgtgtcagcgtctgcg
gcccacatcctgggcgaggtttgccgggagaagcaggaggcggccgtcccgctggtgcgg
ctcttcctacactatggcagggtggtgccattcatcagtgccatcgccagcgcggaggtg
aagcggacccaggaccccaacaccatcttccgaggaaactcactggcgtccaagtgcatc
gacgagaccatgaagctggcggggatgcattacctgcatgtcaccctgaagcccgccatc
gaggagatatgccagagccacaaaccctgtgaaatcgaccctgtgaagttgaaagacgga
gaaaaccttgaaaacaacatggagaacctacggcagtatgtggaccgcgtcttccacgcc
atcactgagtctggggtgagctgcccgaccgtcatgtgtgacatcttcttctccctccgg
gaggcggcggccaagcgcttccaggatgacccggacgtcaggtacactgcagtgagcagc
ttcatcttcctgaggttctttgcgcccgccattctctcccccaacctcttccagctcacg
ccgcaccacacggacccccagacgtccaggacgctgacattgatctccaagaccgttcag
accctcggcagcctgtccaagtccaaatctgcgagttttaaggagtcctacatggctaca
ttttatgaattcttcaatgagcagaaatatgctgatgcggtgaagaacttcttggatctg
atttcgtcctcggggagaagagaccccaagagtgttgagcagcccatcgtgcttaaagaa
gggttcatgatcaagagggcccaaggacggaagcgctttgggatgaagaattttaagaag
agatggtttcgcttgaccaaccatgaatttacctaccacaaaagcaaaggggaccagcct
ctctacagcattcccatcgagaacatcctggcagtggagaagctggaggaggagtctttc
aaaatgaaaaacatgttccaggtcatccagccagagcgtgcgctgtacatccaggccaac
aactgcgtggaggccaaggactggatcgacattctcaccaaagtgagccagtgcaaccag
aagcgcctcaccgtctaccacccgtccgcctacctgagcggccactggctgtgctgtagg
gcgccatccgactcggctccgggctgctcgccctgcactggcggcctcccagccaacatc
cagctggacattgatggggaccgtgagacggagcgtatctactccctcttcaacttgtac
atgagcaagctggagaagatgcaggaggcctgtgggagcaaatctgtgtatgacggcccg
gagcaggaggagtattcgacgttcgtcattgacgacccccaggagacctacaagacgcta
aagcaagtcatcgctggggttggggctttggagcaggagcacgcccagtataagagggac
aagttcaagaagacgaaatatggaagccaggagcaccccatcggagacaagagcttccag
aactacatccggcagcagtccgagacctccactcattccatttaa

KEGG   Homo sapiens (human): 5921Help
Entry
5921              CDS       T01001                                 

Gene name
RASA1, CM-AVM, CMAVM, CMAVM1, GAP, PKWS, RASA, RASGAP, p120, p120GAP, p120RASGAP
Definition
(RefSeq) RAS p21 protein activator 1
  KO
K04352  Ras GTPase-activating protein 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04010  MAPK signaling pathway
hsa04014  Ras signaling pathway
hsa04360  Axon guidance
Disease
H00532  Parkes Weber syndrome
H02043  Capillary malformation-arteriovenous malformation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    5921 (RASA1)
   04010 MAPK signaling pathway
    5921 (RASA1)
 09150 Organismal Systems
  09158 Development and regeneration
   04360 Axon guidance
    5921 (RASA1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: SH2 RasGAP PH C2 SH3_1 SH3_9 SH2_2 PH_11 SH3_2
Motif
Other DBs
NCBI-GeneID: 5921
NCBI-ProteinID: NP_002881
OMIM: 139150
HGNC: 9871
Ensembl: ENSG00000145715
Vega: OTTHUMG00000162605
Pharos: P20936(Tbio)
UniProt: P20936 Q59GK3
Structure
PDB: 

Position
5q14.3
AA seq 1047 aa AA seqDB search
MMAAEAGSEEGGPVTAGAGGGGAAAGSSAYPAVCRVKIPAALPVAAAPYPGLVETGVAGT
LGGGAALGSEFLGAGSVAGALGGAGLTGGGTAAGVAGAAAGVAGAAVAGPSGDMALTKLP
TSLLAETLGPGGGFPPLPPPPYLPPLGAGLGTVDEGDSLDGPEYEEEEVAIPLTAPPTNQ
WYHGKLDRTIAEERLRQAGKSGSYLIRESDRRPGSFVLSFLSQMNVVNHFRIIAMCGDYY
IGGRRFSSLSDLIGYYSHVSCLLKGEKLLYPVAPPEPVEDRRRVRAILPYTKVPDTDEIS
FLKGDMFIVHNELEDGWMWVTNLRTDEQGLIVEDLVEEVGREEDPHEGKIWFHGKISKQE
AYNLLMTVGQVCSFLVRPSDNTPGDYSLYFRTNENIQRFKICPTPNNQFMMGGRYYNSIG
DIIDHYRKEQIVEGYYLKEPVPMQDQEQVLNDTVDGKEIYNTIRRKTKDAFYKNIVKKGY
LLKKGKGKRWKNLYFILEGSDAQLIYFESEKRATKPKGLIDLSVCSVYVVHDSLFGRPNC
FQIVVQHFSEEHYIFYFAGETPEQAEDWMKGLQAFCNLRKSSPGTSNKRLRQVSSLVLHI
EEAHKLPVKHFTNPYCNIYLNSVQVAKTHAREGQNPVWSEEFVFDDLPPDINRFEITLSN
KTKKSKDPDILFMRCQLSRLQKGHATDEWFLLSSHIPLKGIEPGSLRVRARYSMEKIMPE
EEYSEFKELILQKELHVVYALSHVCGQDRTLLASILLRIFLHEKLESLLLCTLNDREISM
EDEATTLFRATTLASTLMEQYMKATATQFVHHALKDSILKIMESKQSCELSPSKLEKNED
VNTNLTHLLNILSELVEKIFMASEILPPTLRYIYGCLQKSVQHKWPTNTTMRTRVVSGFV
FLRLICPAILNPRMFNIISDSPSPIAARTLILVAKSVQNLANLVEFGAKEPYMEGVNPFI
KSNKHRMIMFLDELGNVPELPDTTEHSRTDLSRDLAALHEICVAHSDELRTLSNERGAQQ
HVLKKLLAITELLQQKQNQYTKTNDVR
NT seq 3144 nt NT seq  +upstreamnt  +downstreamnt
atgatggcggccgaggccggcagtgaggagggcggcccggtaacagccggagctggagga
ggcggcgcggcagcgggctccagtgcctatcccgcagtgtgtcgggtgaagatacccgcg
gccctgcctgtggcagccgccccctatcctgggctggtggagaccggagtggctggaact
ctgggtggcggagccgctttggggtcagagttcctaggagccgggtctgtggcaggggca
ctggggggagctggactgacagggggaggtactgctgctggcgtagctggtgctgctgct
ggcgtggccggtgctgctgttgctggacctagtggagacatggctctcaccaaactgccc
acttcgttgcttgctgagactctcgggccaggcggcggttttccccctctgccccctccc
ccttacctgccccctttgggggcgggcctcgggacagtggacgaaggtgactctctggat
ggaccagaatacgaggaggaagaggtggccataccgttgaccgctcctccaactaaccag
tggtatcacggaaaacttgacagaacgatagcagaagaacgcctcaggcaggcagggaag
tctggcagttatcttataagagagagtgatcggaggccagggtcctttgtactttcattt
cttagccagatgaatgttgtcaaccattttaggattattgctatgtgtggagattactac
attggtggaagacgtttttcttcactgtcagacctaataggttattacagtcatgtttct
tgtttgcttaaaggagaaaaattactttacccagttgcaccaccagagccagtagaagat
agaaggcgtgtacgagctattctaccttacacaaaagtaccagacactgatgaaataagt
ttcttaaaaggagatatgttcattgttcataatgaattagaagatggatggatgtgggtt
acaaatttaagaacagatgaacaaggccttattgttgaagacctagtagaagaggtgggc
cgggaagaagatccacatgaaggaaaaatatggttccatgggaagatttccaaacaggaa
gcttataatttactaatgacagttggtcaagtctgcagttttcttgtgaggccctcagat
aatactcctggcgattattcactttatttccggaccaatgaaaatattcagcgatttaaa
atatgtccaacgccaaacaatcagtttatgatgggaggccggtattataacagcattggg
gacatcatagatcactatcgaaaagaacagattgttgaaggatattatcttaaggaacct
gtaccaatgcaggatcaagaacaagtactcaatgacacagtggatggcaaggaaatctat
aataccatccgtcgtaaaacaaaggatgccttttataaaaacattgttaagaaaggttat
cttctgaaaaagggcaaaggaaaacgttggaaaaatttatattttatcttagagggtagt
gatgcccaacttatttattttgaaagcgaaaaacgagctaccaaaccaaaaggattaata
gatctcagtgtatgttctgtctatgtcgttcatgatagtctctttggcaggccaaactgt
tttcagatagtagttcagcactttagtgaagaacattacatcttttactttgcaggagaa
actccagaacaagcagaggattggatgaaaggtctgcaggcattttgcaatttacggaaa
agtagtccagggacatccaataaacgccttcgtcaggtcagcagccttgttttacatatt
gaagaagcccataaactcccagtaaaacattttactaatccatattgtaacatctacctg
aatagtgtccaagtagcaaaaactcatgcaagggaagggcaaaacccagtatggtcagaa
gagtttgtctttgatgatcttcctcctgacatcaatagatttgaaataactcttagtaat
aaaacaaagaaaagcaaagatcctgatatcttatttatgcgctgccagttgagccgatta
cagaaagggcatgccacagatgaatggtttctgctcagctcccatataccattaaaaggt
attgaaccagggtccctgcgtgttcgagcacgatactctatggaaaaaatcatgccagaa
gaagagtacagtgaatttaaagagcttatactgcaaaaggaacttcatgtagtctatgct
ttatcacatgtatgtggacaagaccgaacactactggccagcatcctactgaggattttt
cttcacgaaaagcttgaatcgttgttgttatgcacactaaatgacagagaaataagcatg
gaagatgaagccactaccctatttcgagccacaacacttgcaagcaccttgatggagcag
tatatgaaagccactgctacacagtttgttcatcatgctttgaaagactctattttaaag
ataatggaaagcaagcagtcttgtgagttaagtccatcaaagttagaaaaaaatgaagat
gtgaacactaatttaacacacctattgaacatactttcagagcttgtggagaaaatattc
atggcttcagaaatacttccaccgacattgagatatatttatgggtgtttacagaaatct
gttcagcataagtggcctacaaataccaccatgagaacaagagttgttagtggttttgtt
tttcttcgactcatctgtcctgccatcctgaatccacggatgttcaatatcatctcagat
tctccatctcctattgctgcaagaacactgatattagtggctaaatctgtgcagaactta
gcaaatcttgtggaatttggagctaaggagccctacatggaaggtgtcaatccattcatc
aaaagcaacaaacatcgtatgatcatgtttttagatgaacttgggaatgtacctgaactt
ccggacactacagagcattctagaacggacctgtcccgtgatttagcagcattgcatgag
atttgcgtggctcattcagatgaacttcgaacgctcagtaatgagcgtggtgcacagcag
cacgtattgaaaaagcttctggctataacagaactgcttcaacaaaaacaaaaccagtat
acaaaaaccaatgatgtcaggtag

KEGG   Homo sapiens (human): 5922Help
Entry
5922              CDS       T01001                                 

Gene name
RASA2, GAP1M
Definition
(RefSeq) RAS p21 protein activator 2
  KO
K08053  Ras GTPase-activating protein 2
Organism
hsa  Homo sapiens (human)
Pathway
hsa04010  MAPK signaling pathway
hsa04014  Ras signaling pathway
hsa05203  Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    5922 (RASA2)
   04010 MAPK signaling pathway
    5922 (RASA2)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    5922 (RASA2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: C2 RasGAP PH BTK PH_8 PH_3
Motif
Other DBs
NCBI-GeneID: 5922
NCBI-ProteinID: NP_001290174
OMIM: 601589
HGNC: 9872
Ensembl: ENSG00000155903
Vega: OTTHUMG00000160221
Pharos: Q15283(Tdark)
UniProt: Q15283
Position
3q23
AA seq 850 aa AA seqDB search
MAAAAPAAAAASSEAPAASATAEPEAGDQDSREVRVLQSLRGKICEAKNLLPYLGPHKMR
DCFCTINLDQEEVYRTQVVEKSLSPFFSEEFYFEIPRTFQYLSFYVYDKNVLQRDLRIGK
VAIKKEDLCNHSGKETWFSLQPVDSNSEVQGKVHLELKLNELITENGTVCQQLVVHIKAC
HGLPLINGQSCDPYATVSLVGPSRNDQKKTKVKKKTSNPQFNEIFYFEVTRSSSYTRKSQ
FQVEEEDIEKLEIRIDLWNNGNLVQDVFLGEIKVPVNVLRTDSSHQAWYLLQPRDNGNKS
SKTDDLGSLRLNICYTEDYVLPSEYYGPLKTLLLKSPDVQPISASAAYILSEICRDKNDA
VLPLVRLLLHHDKLVPFATAVAELDLKDTQDANTIFRGNSLATRCLDEMMKIVGGHYLKV
TLKPILDEICDSSKSCEIDPIKLKEGDNVENNKENLRYYVDKLFNTIVKSSMSCPTVMCD
IFYSLRQMATQRFPNDPHVQYSAVSSFVFLRFFAVAVVSPHTFHLRPHHPDAQTIRTLTL
ISKTIQTLGSWGSLSKSKSSFKETFMCEFFKMFQEEGYIIAVKKFLDEISSTETKESSGT
SEPVHLKEGEMYKRAQGRTRIGKKNFKKRWFCLTSRELTYHKQPGSKDAIYTIPVKNILA
VEKLEESSFNKKNMFQVIHTEKPLYVQANNCVEANEWIDVLCRVSRCNQNRLSFYHPSVY
LNGNWLCCQETGENTLGCKPCTAGVPADIQIDIDEDRETERIYSLFTLSLLKLQKMEEAC
GTIAVYQGPQKEPDDYSNFVIEDSVTTFKTIQQIKSIIEKLDEPHEKYRKKRSSSAKYGS
KENPIVGKAS
NT seq 2553 nt NT seq  +upstreamnt  +downstreamnt
atggcggcggcggcgcctgctgctgcggcggcttcttccgaggcgccagcggcgagtgcg
actgcagagcccgaggccggggaccaggacagtcgcgaggttcgagtgttgcagagcctg
cggggcaagatctgtgaagcaaaaaatttattgccatatcttggaccccacaaaatgaga
gattgtttctgtaccataaatttggaccaggaagaagtttatcgtacccaagttgtggaa
aaatctttaagcccatttttcagtgaagaattttactttgagattccaagaactttccag
tatttgtctttctatgtttatgataagaatgttttacaaagagatctccgtataggaaaa
gtagccatcaaaaaagaagacttgtgtaatcacagtggcaaagaaacttggttttcatta
cagcctgttgactccaattcagaggttcagggtaaagttcaccttgaattaaaactgaat
gaactgataacggagaatggaactgtatgccagcagcttgttgtacacatcaaggcatgc
catgggttgcctctcataaatggccaaagctgtgacccttatgcaacagtttctctagtg
ggcccttctaggaatgaccaaaagaagacaaaagtaaagaagaaaacaagcaatccgcag
tttaatgaaatcttttattttgaggtaaccagatccagtagttacaccagaaagtcccag
ttccaggtagaagaggaggacattgaaaagctagaaatcaggatcgacttgtggaacaat
ggaaacctagtccaagatgttttcctaggtgagattaaggttcctgtgaacgtattaaga
actgattcctctcatcaagcctggtacttgctacagccaagagacaatggaaacaagtca
tccaaaactgatgacctggggtctcttcgattaaatatatgttatacagaagactacgtg
cttccttcagagtactatggtcctttgaaaactttgctgctaaaatcaccagatgttcaa
ccaatatctgcctcagctgcttacattttgagtgaaatatgtcgagataaaaatgatgct
gttttgccccttgtacgactgctgctgcaccatgataaacttgttccttttgccactgct
gtggctgaattagacttgaaggatacacaagatgcaaacacaatttttagaggaaattcc
ctggctacccgatgtctggatgagatgatgaaaatagtgggagggcactacctgaaagta
acattaaaacctattcttgatgagatatgtgactcctcaaaatcctgtgaaatcgatcct
attaaattgaaagagggagataatgtagaaaataataaggagaatctgcgctactatgta
gacaagttattcaatacaattgtaaaatcaagtatgagctgccccactgtaatgtgtgat
atcttttattctctaaggcagatggctactcagagatttcctaatgaccctcatgttcag
tattctgcagtgagcagctttgtatttcttcgtttctttgctgtagccgtagtatcacct
catacttttcatttgcgacctcatcatccagatgcacagacaattagaacattaactctc
atctcaaaaactatacaaactttgggaagctgggggagtctgtccaaaagcaagtcaagt
ttcaaagagacattcatgtgtgaatttttcaaaatgtttcaagaagaaggatatattata
gcagttaaaaagttcttggatgaaatttcatctactgaaactaaagagtccagtggtacg
agtgagcctgtgcacctgaaagaaggtgagatgtataaaagagctcaaggaagaactcgg
attggaaaaaagaattttaagaaacgatggttctgcttaacaagcagagagctcacctac
cacaaacagccaggtagcaaagatgcaatctacacaatcccagtaaaaaacattcttgct
gtggaaaaactggaagagagctctttcaacaagaaaaatatgttccaagtaatacatacg
gagaaaccactctatgtccaggcaaataactgtgtagaagctaatgaatggatagacgta
ctctgcagggtgagccgatgcaatcaaaacaggctcagtttttatcatccctctgtgtat
ctgaacggaaattggctctgctgtcaggagactggtgaaaacactctcggctgcaagcca
tgtactgcaggtgtccctgcagacatccaaatagatattgatgaagacagagaaacagaa
agaatttattccctttttaccctcagtttacttaagctgcagaagatggaagaggcttgt
ggaactattgcagtctatcaaggaccacagaaagagcctgatgattattctaactttgta
atcgaggattctgtaacaacctttaagacaattcagcaaataaaaagcataattgagaag
ctggatgaacctcatgaaaaatataggaagaaaagatccagtagtgcaaaatatgggagc
aaggaaaatccaattgttgggaaagcatcttag

KEGG   Homo sapiens (human): 64926Help
Entry
64926             CDS       T01001                                 

Gene name
RASAL3
Definition
(RefSeq) RAS protein activator like 3
  KO
K17634  RAS protein activator-like 3
Organism
hsa  Homo sapiens (human)
Pathway
hsa04014  Ras signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    64926 (RASAL3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: RasGAP ATG16 Baculo_PEP_C C2 Dynamitin CtIP_N TMF_DNA_bd BAR_3 KASH_CCD DUF4763 PH_6 DUF4407 PH TPR_MLP1_2 Snapin_Pallidin DUF16 ZapB GAS Spc7 Leu_zip TMPIT
Motif
Other DBs
NCBI-GeneID: 64926
NCBI-ProteinID: NP_075055
OMIM: 616561
HGNC: 26129
Ensembl: ENSG00000105122
Vega: OTTHUMG00000182450
Pharos: Q86YV0(Tbio)
UniProt: Q86YV0
Position
19p13.12
AA seq 1011 aa AA seqDB search
MDPPSPSRTSQTQPTATSPLTSYRWHTGGGGEKAAGGFRWGRFAGWGRALSHQEPMVSTQ
PAPRSIFRRVLSAPPKESRTSRLRLSKALWGRHKNPPPEPDPEPEQEAPELEPEPELEPP
TPQIPEAPTPNVPVWDIGGFTLLDGKLVLLGGEEEGPRRPRVGSASSEGSIHVAMGNFRD
PDRMPGKTEPETAGPNQVHNVRGLLKRLKEKKKARLEPRDGPPSALGSRESLATLSELDL
GAERDVRIWPLHPSLLGEPHCFQVTWTGGSRCFSCRSAAERDRWIEDLRRQFQPTQDNVE
REETWLSVWVHEAKGLPRAAAGAPGVRAELWLDGALLARTAPRAGPGQLFWAERFHFEAL
PPARRLSLRLRGLGPGSAVLGRVALALEELDAPRAPAAGLERWFPLLGAPAGAALRARIR
ARRLRVLPSERYKELAEFLTFHYARLCGALEPALPAQAKEELAAAMVRVLRATGRAQALV
TDLGTAELARCGGREALLFRENTLATKAIDEYMKLVAQDYLQETLGQVVRRLCASTEDCE
VDPSKCPASELPEHQARLRNSCEEVFETIIHSYDWFPAELGIVFSSWREACKERGSEVLG
PRLVCASLFLRLLCPAILAPSLFGLAPDHPAPGPARTLTLIAKVIQNLANRAPFGEKEAY
MGFMNSFLEEHGPAMQCFLDQVAMVDVDAAPSGYQGSGDLALQLAVLHAQLCTIFAELDQ
TTRDTLEPLPTILRAIEEGQPVLVSVPMRLPLPPAQVHSSLSAGEKPGFLAPRDLPKHTP
LISKSQSLRSVRRSESWARPRPDEERPLRRPRPVQRTQSVPVRRPARRRQSAGPWPRPKG
SLSMGPAPRARPWTRDSASLPRKPSVPWQRQMDQPQDRNQALGTHRPVNKLAELQCEVAA
LREEQKVLSRLVESLSTQIRALTEQQEQLRGQLQDLDSRLRAGSSEFDSEHNLTSNEGHS
LKNLEHRLNEMERTQAQLRDAVQSLQLSPRTRGSWSQPQPLKAPCLNGDTT
NT seq 3036 nt NT seq  +upstreamnt  +downstreamnt
atggacccaccgtcgccaagccggacctcccaaacccagcccacagccacctctccgctg
acttcctaccgctggcacacagggggcggtggggagaaggcggctggagggttccgctgg
ggccgctttgctggctggggcagggccctgagccaccaggagcccatggtcagcacccag
ccagcccctcgctcgatattccgtcgggtcctatctgcgcctcccaaggagtcacggacc
agtcgccttcgactctccaaggccctctgggggaggcataagaacccaccgccggagcca
gacccggagccggagcaggaggccccagagctggagccggagccagagctggagccccct
accccacagatccctgaggcccccacacccaacgtgcctgtctgggacattgggggcttc
accctgcttgatgggaagctggtgctgcttggaggagaggaggagggtcctcgaaggccc
cgggtgggaagtgctagctccgagggcagcatccacgtggccatggggaacttcagggat
ccagatcggatgcctggaaaaacagaaccggagactgctggtcccaaccaggtccacaac
gttcgggggttgctcaagaggctgaaagagaagaaaaaggccaggttggagccccgggat
ggaccccccagtgctctgggctctagggagtcgctggccacactctctgaactggacctg
ggtgccgagcgggatgtgcggatctggccactgcaccccagcctcctgggggagccccac
tgctttcaggtaacctggacgggtggaagccgctgcttctcttgtcgctcggccgctgag
agagaccgctggatcgaggaccttcgtcgccaattccagcccacccaggacaacgtggag
cgggaagagacatggctgagcgtgtgggtgcacgaagcgaaggggcttccccgagcagcg
gcgggggcacccggcgtgcgcgccgagctgtggctggatggcgcgctgctggcacgcacg
gcgcctcgggccggcccaggccagctcttctgggccgagcgcttccacttcgaggcgctg
ccaccggcacgtcgcctgtcgctgcggctgcgcggcttgggcccgggaagcgcggtgctg
ggccgcgtggccctggcgctggaggagctggacgccccacgcgcgcctgccgccggtctg
gagcgctggttcccgctgctcggggcgccggcgggcgcagcgctgcgggcgcggattcgg
gcgcgtcgcctgcgcgtgctgccgtccgagcgctacaaggagctggcggagttcctcacc
ttccactatgcgcgcctctgcggggccctggagcccgcgctgcctgcgcaggccaaggag
gagctggcggcagccatggtgcgcgtgctgcgggccaccggccgggcgcaggcgctggtg
actgacctgggcactgcggagctggcgcgctgtggaggccgtgaggcgctgctgttccgg
gaaaacacattggccaccaaggctatcgatgagtacatgaagctcgtggcacaggattac
ctccaggagaccctgggacaggttgtgcggcgtctctgtgcttctactgaggactgtgaa
gtggaccccagcaaatgtccagcctcggagctgccagagcaccaggccagacttcggaac
agctgcgaggaggtcttcgaaaccattatccattcctacgactggttccctgcggagctg
ggcatcgtgttctcaagctggcgagaagcatgtaaagaacgtggctctgaggtgctgggc
ccccgactggtgtgcgcctccctcttcctgcggctcctgtgccctgccatcctggcaccc
agcctctttggtttggcaccagaccatccagcacccggcccagcccgcaccctcacactg
attgccaaggtcatccagaacctcgccaaccgtgccccgttcggtgagaaggaggcctac
atgggcttcatgaatagcttcctggaggaacatggaccagccatgcaatgcttcctggac
caggtagccatggtggatgtggatgctgcccccagtggttaccagggcagtggtgatctg
gccctccagttagctgtcctgcatgcccagctctgtacaatttttgctgagcttgaccag
acaacccgagacaccctggaaccactgcccaccatcctgcgagccattgaggagggccag
cctgtgcttgtgtcagtgccaatgcgtctcccactgcccccggcccaggtccactccagc
ctctccgcaggggagaagcccggcttcctggccccccgggacctccccaagcacacccct
ctcatctccaagagccagtctctgcgcagcgttcgccgctcagagagttgggcccggcca
cggccggacgaagagcggcccctgcggcggccccggccggtgcagcgcacgcagagtgtc
ccggtccggcgtcctgcccgccgccgccaatctgcggggccctggccgcgacccaaaggc
tccctgagcatgggaccagcgccccgcgcccggccttggacccgggactccgcctcgctg
cctcggaagccgtcggtaccctggcagcgccaaatggaccagccgcaagaccgaaaccag
gcactgggcacgcaccgacctgtgaacaagttggcagagctgcagtgcgaggtggccgct
ctgcgtgaggagcagaaagtgctgtcccgcctcgtggagtcgctgagcacccaaatccgg
gccttgacggagcagcaggagcagctgcggggccagctgcaggatctggactccaggctc
cgtgctgggagctcagagtttgattcagagcacaacctaacaagcaatgaagggcacagt
ctgaaaaacctggagcaccgcctaaatgagatggagagaactcaggctcagctgagggat
gctgtccagagcctgcagctttctccaaggacgcgggggtcttggagtcaaccccagccc
ctcaaagcaccctgcctcaatggagacaccacctga

KEGG   Homo sapiens (human): 8437Help
Entry
8437              CDS       T01001                                 

Gene name
RASAL1, RASAL
Definition
(RefSeq) RAS protein activator like 1
  KO
K17632  RAS protein activator-like 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04014  Ras signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    8437 (RASAL1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: C2 RasGAP PH BTK
Motif
Other DBs
NCBI-GeneID: 8437
NCBI-ProteinID: NP_004649
OMIM: 604118
HGNC: 9873
Ensembl: ENSG00000111344
Vega: OTTHUMG00000169705
Pharos: O95294(Tbio)
UniProt: O95294
Position
12q24.13
AA seq 804 aa AA seqDB search
MAKSSSLNVRVVEGRALPAKDVSGSSDPYCLVKVDDEVVARTATVWRSLGPFWGEEYTVH
LPLDFHQLAFYVLDEDTVGHDDIIGKISLSREAITADPRGIDSWINLSRVDPDAEVQGEI
CLSVQMLEDGQGRCLRCHVLQARDLAPRDISGTSDPFARVFWGSQSLETSTIKKTRFPHW
DEVLELREMPGAPSPLRVELWDWDMVGKNDFLGMVEFSPKTLQQKPPKGWFRLLPFPRAE
EDSGGNLGALRVKVRLIEDRVLPSQCYQPLMELLMESVQGPAEEDTASPLALLEELTLGD
CRQDLATKLVKLFLGRGLAGRFLDYLTRREVARTMDPNTLFRSNSLASKSMEQFMKLVGM
PYLHEVLKPVISRVFEEKKYMELDPCKMDLGRTRRISFKGALSEEQMRETSLGLLTGYLG
PIVDAIVGSVGRCPPAMRLAFKQLHRRVEERFPQAEHQDVKYLAISGFLFLRFFAPAILT
PKLFDLRDQHADPQTSRSLLLLAKAVQSIGNLGQQLGQGKELWMAPLHPFLLQCVSRVRD
FLDRLVDVDGDEAGVPARALFPPSAIVREGYLLKRKEEPAGLATRFAFKKRYVWLSGETL
SFSKSPEWQMCHSIPVSHIRAVERVDEGAFQLPHVMQVVTQDGTGALHTTYLQCKNVNEL
NQWLSALRKASAPNPNKLAACHPGAFRSARWTCCLQAERSAAGCSRTHSAVTLGDWSDPL
DPDAEAQTVYRQLLLGRDQLRLKLLEDSNMDTTLEADTGACPEVLARQRAATARLLEVLA
DLDRAHEEFQQQERGKAALGPLGP
NT seq 2415 nt NT seq  +upstreamnt  +downstreamnt
atggccaagagcagctccctgaatgttcgcgtggtggagggccgcgcgctgcctgccaag
gacgtgtctgggagcagcgacccctactgcctagtgaaagtggacgacgaggtggtggcc
aggacagctactgtctggaggagcctgggccccttctggggggaggagtacacggtgcac
ctgcctctggatttccaccagctggccttctacgtgctggatgaggacactgtcgggcac
gacgacatcatcggcaagatctcgctgagcagggaggcgattacagccgacccccgaggg
attgacagctggattaacttgagccgagtggacccagatgcagaagtgcagggtgagatc
tgcctgtcagtgcagatgctggaggatgggcagggccgctgccttcgctgccatgtgctt
caggccagggacctggctcccagagacatctctggcacatctgacccatttgcacgtgtg
ttttggggcagccagagcttggagacctcaaccatcaagaagactcgcttcccgcactgg
gatgaagtgctggagctgcgggagatgccaggtgccccgtccccactgcgggtggagctc
tgggactgggacatggtgggcaagaatgacttcttgggcatggtggagttctctccaaag
accctccagcagaagccacctaaaggctggttccgcctcctgccctttcccagagccgag
gaggattctggggggaacctgggtgccctgcgagtgaaggtacgcctgattgaggaccgc
gtcctgccctcccagtgctaccagcctctcatggagctgctcatggagtctgtgcagggg
ccagcagaggaggacactgctagccccttggctttgctggaagagctgaccttgggggac
tgccgccaggaccttgccaccaagctggtgaaactctttcttggccggggactggctggg
cgctttctggactatctcacccggcgtgaggtggctcggaccatggaccccaacaccctc
ttccgttctaactccctggcatccaagtcgatggaacagtttatgaagctcgtgggcatg
ccctacctgcacgaggtcctgaagcctgtgattagccgtgtctttgaggagaagaagtac
atggagctggatccctgcaagatggacctgggccgcacccggaggatctccttcaaaggc
gcactctcggaggagcagatgcgggagaccagcctggggctgctgacgggctacctgggg
cccatcgtggacgccatcgtgggctccgtggggcgctgcccgcccgccatgcgcctcgcc
ttcaagcagctgcaccggcgagtggaggagcgcttcccccaggccgagcaccaggatgtg
aagtacctggccatcagtggatttctcttcttgcgattcttcgcacctgccatccttacc
ccaaagctgtttgaccttcgggaccaacacgcggacccccagactagccgctcactgctg
ttgcttgccaaggctgtgcagagcattggaaacctgggccagcagctgggccaaggcaag
gaactgtggatggcccccctgcaccccttcctgctgcagtgtgtctcacgtgtgagagac
ttcctggaccggctggtggatgtggatggggatgaagctggtgtcccagccagggccctg
ttcccgccctcggccattgttcgagaaggctatctgctgaagcgcaaggaggagcctgcc
ggcctggccacgcgctttgccttcaagaagcgctacgtctggctcagcggggagaccctc
tccttctccaagagtcctgagtggcagatgtgtcactccatccccgtgtctcacatccgc
gccgtggagcgcgtagacgagggcgccttccaactgccccacgtgatgcaggtggtgacg
caggacggcacgggggcgctgcacaccacctacctccagtgcaagaatgtgaatgagctc
aaccagtggctctcggccttgcgcaaggccagcgcccccaacccgaacaagctggccgcc
tgccaccccggtgccttccgcagcgcgcgctggacctgctgcctccaggctgagcgctca
gccgccggctgcagccgtacacactcagctgtcaccctgggggactggagtgacccactg
gatcctgatgctgaggcccagacagtgtatcggcagctgctcctggggcgggaccagctc
aggctgaaattactggaggattctaacatggatacaactctggaggcagacacaggggcc
tgtcctgaggtcctggcccggcaaagagcagcaactgcccgcctgctggaggtgctcgca
gacctggatcgtgcccacgaggagttccagcagcaggagcgagggaaggcggccctgggc
ccccttggcccctaa

KEGG   Homo sapiens (human): 8831Help
Entry
8831              CDS       T01001                                 

Gene name
SYNGAP1, MRD5, RASA1, RASA5, SYNGAP
Definition
(RefSeq) synaptic Ras GTPase activating protein 1
  KO
K17631  Ras/Rap GTPase-activating protein SynGAP
Organism
hsa  Homo sapiens (human)
Pathway
hsa04014  Ras signaling pathway
Disease
H00773  Autosomal dominant mental retardation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    8831 (SYNGAP1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: DUF3498 RasGAP C2 PH Exonuc_VII_L PH_2 PH_6 UPF0242
Motif
Other DBs
NCBI-GeneID: 8831
NCBI-ProteinID: NP_006763
OMIM: 603384
HGNC: 11497
Ensembl: ENSG00000197283
Vega: OTTHUMG00000031096
Pharos: Q96PV0(Tbio)
UniProt: Q96PV0 A0A1U9X8L0
Position
6p21.32
AA seq 1343 aa AA seqDB search
MSRSRASIHRGSIPAMSYAPFRDVRGPSMHRTQYVHSPYDRPGWNPRFCIISGNQLLMLD
EDEIHPLLIRDRRSESSRNKLLRRTVSVPVEGRPHGEHEYHLGRSRRKSVPGGKQYSMEG
APAAPFRPSQGFLSRRLKSSIKRTKSQPKLDRTSSFRQILPRFRSADHDRARLMQSFKES
HSHESLLSPSSAAEALELNLDEDSIIKPVHSSILGQEFCFEVTTSSGTKCFACRSAAERD
KWIENLQRAVKPNKDNSRRVDNVLKLWIIEARELPPKKRYYCELCLDDMLYARTTSKPRS
ASGDTVFWGEHFEFNNLPAVRALRLHLYRDSDKKRKKDKAGYVGLVTVPVATLAGRHFTE
QWYPVTLPTGSGGSGGMGSGGGGGSGGGSGGKGKGGCPAVRLKARYQTMSILPMELYKEF
AEYVTNHYRMLCAVLEPALNVKGKEEVASALVHILQSTGKAKDFLSDMAMSEVDRFMERE
HLIFRENTLATKAIEEYMRLIGQKYLKDAIGEFIRALYESEENCEVDPIKCTASSLAEHQ
ANLRMCCELALCKVVNSHCVFPRELKEVFASWRLRCAERGREDIADRLISASLFLRFLCP
AIMSPSLFGLMQEYPDEQTSRTLTLIAKVIQNLANFSKFTSKEDFLGFMNEFLELEWGSM
QQFLYEISNLDTLTNSSSFEGYIDLGRELSTLHALLWEVLPQLSKEALLKLGPLPRLLND
ISTALRNPNIQRQPSRQSERPRPQPVVLRGPSAEMQGYMMRDLNSSIDLQSFMARGLNSS
MDMARLPSPTKEKPPPPPPGGGKDLFYVSRPPLARSSPAYCTSSSDITEPEQKMLSVNKS
VSMLDLQGDGPGGRLNSSSVSNLAAVGDLLHSSQASLTAALGLRPAPAGRLSQGSGSSIT
AAGMRLSQMGVTTDGVPAQQLRIPLSFQNPLFHMAADGPGPPGGHGGGGGHGPPSSHHHH
HHHHHHRGGEPPGDTFAPFHGYSKSEDLSSGVPKPPAASILHSHSYSDEFGPSGTDFTRR
QLSLQDNLQHMLSPPQITIGPQRPAPSGPGGGSGGGSGGGGGGQPPPLQRGKSQQLTVSA
AQKPRPSSGNLLQSPEPSYGPARPRQQSLSKEGSIGGSGGSGGGGGGGLKPSITKQHSQT
PSTLNPTMPASERTVAWVSNMPHLSADIESAHIEREEYKLKEYSKSMDESRLDRVKEYEE
EIHSLKERLHMSNRKLEEYERRLLSQEEQTSKILMQYQARLEQSEKRLRQQQAEKDSQIK
SIIGRLMLVEEELRRDHPAMAEPLPEPKKRLLDAQERQLPPLGPTNPRVTLAPPWNGLAP
PAPPPPPRLQITENGEFRNTADH
NT seq 4032 nt NT seq  +upstreamnt  +downstreamnt
atgagcaggtctcgagcctccatccatcgggggagcatccccgcgatgtcctatgccccc
ttcagagatgtacggggaccctctatgcaccgaacccaatacgttcattccccgtatgat
cgtcctggttggaaccctcggttctgcatcatctcggggaaccagctgctcatgctggat
gaggatgagatacaccccctactgatccgggaccggaggagcgagtccagtcgcaacaaa
ctgctgagacgcacagtctccgtgccggtggaggggcggccccacggcgagcatgaatac
cacttgggtcgctcgaggaggaagagtgtcccaggggggaagcagtacagcatggagggt
gcccctgctgcgcccttccggccctcgcaaggcttcctgagccgacggctaaaaagctcc
atcaaacgaacgaagtcacaacccaaacttgaccggaccagcagctttcgccagatcctg
cctcgcttccgaagtgctgaccatgaccgggcccggctgatgcaaagctttaaggagtca
cactctcatgagtccttgctgagtcctagcagtgcagctgaggcattggagctcaacttg
gatgaagattccattatcaagccagtgcacagctccatcctgggccaggagttctgtttt
gaggtaacaacttcatcaggaacaaaatgctttgcctgtcggtctgcggccgaaagagac
aaatggattgagaatctgcagcgggcagtaaagcccaacaaggacaacagccgccgggta
gacaatgtgctaaagctgtggatcatagaggcccgggagctgccccccaagaagcggtac
tactgtgagctctgcctggatgacatgctgtatgcacgcaccacctccaagccccgctct
gcctctggggacaccgtcttctggggcgagcacttcgagtttaacaacctgccggctgtc
cgtgccctgcggctgcatctgtaccgtgactcagacaaaaagcgcaagaaggacaaggca
ggctatgtcggcctggtgactgtgccagtggccaccctggctgggcgccacttcacagag
cagtggtaccctgtaaccctgccaacaggcagtgggggatctgggggcatgggttcggga
gggggagggggctcggggggtggctcagggggcaagggcaaaggaggttgcccggctgtg
cggctgaaagcacgttaccagacaatgagcatcttgcccatggagctatataaagagttt
gcagagtatgtcaccaaccattatcggatgctgtgtgcagtcttggagcccgccctgaat
gtcaaaggcaaggaggaggttgccagtgcactagttcacatcctgcagagtacaggcaag
gccaaggacttcctttcagacatggccatgtctgaggtagaccggttcatggaacgggag
cacctcatattccgcgagaacacgcttgccactaaagccatagaagagtatatgagactg
attggtcagaaatacctcaaggatgccattggagaattcatccgtgctctgtatgaatct
gaggaaaactgcgaggtagaccctatcaagtgcacagcatccagtttggcagagcaccag
gccaacctgcgaatgtgctgtgagttggccctgtgcaaggtggtcaactcccactgcgtg
ttcccgagggagctgaaggaggtgtttgcttcgtggcggctgcgctgcgcagagcgaggc
cgggaggacatcgcagacaggcttatcagcgcctcactcttcctgcgcttcctctgccca
gcgattatgtcgcccagtctctttgggcttatgcaggagtacccagatgagcagacctca
cgaaccctcaccctcattgccaaggtcatccagaacctggccaacttttccaagtttacc
tcaaaggaggactttctgggcttcatgaatgagtttctggagctggaatggggttccatg
cagcagtttttgtatgagatctccaatctggacacgctaaccaacagcagtagctttgag
ggttacatcgacttgggccgagagctctccacactgcatgccctactctgggaggtgctg
ccccagctcagcaaggaagccctcctgaagctgggtccactgccccggctcctcaacgac
atcagcacagctctgaggaaccccaacatccaaaggcagccaagccgccagagtgagcgg
ccccggcctcagcctgtggtactgcgggggccatcggctgagatgcagggctacatgatg
cgggacctcaacagctccatcgaccttcagtccttcatggctcgaggcctcaacagctct
atggacatggctcgcctcccctccccaaccaaggaaaagccacccccaccaccgcctggt
ggtggtaaagacctgttctatgtaagccgtccacccctggcccgttcctcaccagcatac
tgcacgagcagctcggacatcacagagccagagcagaagatgctgagtgtcaacaagagt
gtgtccatgctggacttacagggtgatgggcctggtggccgcctcaacagcagcagtgtt
tcgaacctggcggccgtaggggacctgctgcactcaagccaggcctcgctgacagcagcc
ttggggctacggcctgcgcctgccggacgcctctcccaggggagtggctcatccatcacg
gcggctggcatgcgcctcagccagatgggtgtcaccacagacggtgtccctgcccagcaa
ctgcgaatccccctctccttccagaaccctctcttccacatggctgctgatgggccaggt
cccccaggcggccatggagggggcggtggccatggcccaccttcctcccatcaccaccac
caccaccatcaccaccaccgaggtggagagccccctggggacacctttgccccattccat
ggctatagcaagagtgaggacctctcttccggggtccccaagccccctgctgcctccatc
cttcatagccacagctacagtgatgagtttggaccctctggcactgacttcacccgtcgg
cagctttcactccaggacaacctgcagcacatgctgtcccctccccagatcaccattggt
ccccagaggccagccccctcagggcctggaggtgggagcggtgggggcagcggtgggggt
ggcgggggccagccgcctccattgcagaggggcaagtctcagcagttgacagtcagcgca
gcccagaaaccccggccatccagcgggaatctattgcagtccccagagccaagttatggc
cccgcccgtccacggcaacagagcctcagcaaggagggcagcattgggggcagcgggggc
agcggtggcggagggggtggggggctgaagccctccatcaccaagcagcattctcagaca
ccatccacattgaaccccacaatgccagcctctgagcggacagtggcctgggtctccaac
atgcctcacctgtcggctgacatcgagagtgcccacatcgagcgggaagagtacaagctc
aaggagtactcaaaatcgatggatgagagccggctggatagggtgaaggagtacgaggag
gagattcactcactgaaagagcggctgcacatgtccaaccggaagctggaagagtatgag
cggaggctgctgtcccaggaagaacaaaccagcaaaatcctgatgcagtatcaggcccga
ctggagcagagtgagaagaggctaaggcagcagcaggcagagaaggattcccagatcaag
agcatcattggcaggctgatgctggtggaggaggagctgcgccgggaccaccccgccatg
gctgagccgctgccagaacccaagaagaggctgctcgacgctcaggagaggcagcttccc
cccttgggtccaacaaacccgcgtgtgacgctggccccaccgtggaatggcctggccccc
ccagccccaccacccccaccccggctgcagattacggagaacggcgagttccgaaacacc
gcagaccactag

KEGG   Homo sapiens (human): 9462Help
Entry
9462              CDS       T01001                                 

Gene name
RASAL2, NGAP
Definition
(RefSeq) RAS protein activator like 2
  KO
K17633  RAS protein activator-like 2
Organism
hsa  Homo sapiens (human)
Pathway
hsa04014  Ras signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    9462 (RASAL2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: DUF3498 RasGAP C2 KASH_CCD PH XLF Bacillus_HBL FAM76
Motif
Other DBs
NCBI-GeneID: 9462
NCBI-ProteinID: NP_004832
OMIM: 606136
HGNC: 9874
Ensembl: ENSG00000075391
Vega: OTTHUMG00000035022
Pharos: Q9UJF2(Tbio)
UniProt: Q9UJF2 A8K2P3
Position
1q25.2
AA seq 1139 aa AA seqDB search
MQTPEVPAERSPRRRSISGTSTSEKPNSMDTANTSPFKVPGFFSKRLKGSIKRTKSQSKL
DRNTSFRLPSLRSTDDRSRGLPKLKESRSHESLLSPCSTVECLDLGRGEPVSVKPLHSSI
LGQDFCFEVTYLSGSKCFSCNSASERDKWMENLRRTVQPNKDNCRRAENVLRLWIIEAKD
LAPKKKYFCELCLDDTLFARTTSKTKADNIFWGEHFEFFSLPPLHSITVHIYKDVEKKKK
KDKNNYVGLVNIPTASVTGRQFVEKWYPVSTPTPNKGKTGGPSIRIKSRFQTITILPMEQ
YKEFAEFVTSNYTMLCSVLEPVISVRNKEELACALVHILQSTGRAKDFLTDLVMSEVDRC
GEHDVLIFRENTIATKSIEEYLKLVGQQYLHDALGEFIKALYESDENCEVDPSKCSSSEL
IDHQSNLKMCCELAFCKIINSYCVFPRELKEVFASWKQQCLNRGKQDISERLISASLFLR
FLCPAIMSPSLFNLMQEYPDDRTSRTLTLIAKVIQNLANFAKFGNKEEYMAFMNDFLEHE
WGGMKRFLLEISNPDTISNTPGFDGYIDLGRELSVLHSLLWEVVSQLDKGENSFLQATVA
KLGPLPRVLADITKSLTNPTPIQQQLRRFTEHNSSPNVSGSLSSGLQKIFEDPTDSDLHK
LKSPSQDNTDSYFRGKTLLLVQQASSQSMTYSEKDERESSLPNGRSVSLMDLQDTHAAQV
EHASVMLDVPIRLTGSQLSITQVASIKQLRETQSTPQSAPQVRRPLHPALNQPGGLQPLS
FQNPVYHLNNPIPAMPKASIDSSLENLSTASSRSQSNSEDFKLSGPSNSSMEDFTKRSTQ
SEDFSRRHTVPDRHIPLALPRQNSTGQAQIRKVDQGGLGARAKAPPSLPHSASLRSTGSM
SVVSAALVAEPVQNGSRSRQQSSSSRESPVPKVRAIQRQQTQQVQSPVDSATMSPVERTA
AWVLNNGQYEEDVEETEQNLDEAKHAEKYEQEITKLKERLRVSSRRLEEYERRLLVQEQQ
MQKLLLEYKARLEDSEERLRRQQEEKDSQMKSIISRLMAVEEELKKDHAEMQAVIDAKQK
IIDAQEKRIVSLDSANTRLMSALTQVKERYSMQVRNGISPTNPTKLSITENGEFKNSSC
NT seq 3420 nt NT seq  +upstreamnt  +downstreamnt
atgcagaccccagaggtaccagcagaaaggtcccctcgtagacggagtatctcagggacc
agtacatcagagaaacccaactccatggacactgcaaatacctcacccttcaaagtacca
ggattcttcagcaagcgcctgaaaggctccatcaagaggaccaaaagccagtcaaagctt
gacagaaacacgagctttcggcttccatcccttcgcagtacagatgacaggtctcgtggg
ctgcctaaactaaaagagtcacgttcccatgaatccttgctgagcccatgcagcacagtg
gaatgtctggatcttggtagaggggaacctgtatcagtgaaaccacttcatagtagcatc
cttggacaagacttctgctttgaggttacctacttaagtggaagtaaatgcttcagctgt
aattctgcttctgagagagacaagtggatggaaaaccttcgcaggacagttcaacctaat
aaggacaattgcaggcgagctgaaaatgttcttcgtttatggatcattgaagccaaggac
cttgcccctaaaaagaaatatttctgcgaactgtgccttgatgataccctctttgctcgt
acaaccagcaagaccaaagcagacaatattttctggggcgaacattttgaattcttcagc
cttccacctcttcatagtatcacagttcacatttacaaggatgtggaaaaaaagaaaaaa
aaggacaagaataattatgtagggctagtcaacatccccactgccagtgtgactggtcgc
caatttgtagaaaagtggtatccagtgagtacacctacacccaacaaaggaaagacagga
ggaccttctattcggattaaatcacgtttccaaactatcaccattctgcctatggagcaa
tacaaagaatttgcagaatttgtcaccagcaactacaccatgctgtgttctgtccttgag
ccagtaattagtgtgagaaataaagaggagttggcttgtgccttagtgcacattcttcaa
agtactggcagagccaaggattttctgactgacttggtgatgtctgaggtggatcgttgt
ggagagcatgatgtcttgatcttcagagagaacactattgccaccaaatccattgaggaa
tacctcaagttggtgggacaacagtatcttcatgacgcactgggggagtttatcaaagct
ttgtatgagtccgatgagaactgtgaagtggatcccagcaaatgttcatctagtgaactg
atagaccatcagagcaacctgaaaatgtgctgtgagctggctttctgcaagatcatcaac
tcttactgtgttttccctcgtgagttgaaagaagtgtttgcatcatggaagcagcagtgc
ctgaaccgtggcaagcaagacatcagcgagaggctcatcagtgcctcattatttctccgt
tttctgtgtccagccattatgtctcccagtcttttcaaccttatgcaggagtatcctgat
gaccgcacatctcggactctaactcttattgccaaggtcattcagaacctggccaacttt
gccaagtttggtaacaaagaggaatacatggcattcatgaatgattttttagaacatgaa
tggggtggaatgaagcgctttcttttggagatctctaatccagacaccatctcaaacacc
ccaggctttgatggttacattgatctgggccgagagctttcagttttgcattccttactg
tgggaagtagtttcccaacttgataagggtgaaaattccttcctacaggcgaccgtggca
aaattggggcctctccctcgtgttcttgctgatattaccaagtcattgactaatcctacg
ccaatacaacagcaactgagacgcttcactgaacataactccagtccaaatgtcagtgga
agcctctcctctgggctgcagaaaatatttgaagaccccactgacagtgatttgcataaa
ctaaaatctccaagccaggacaacacagacagctacttcagagggaaaacattattgctg
gttcagcaagcctcctctcagagcatgacttattctgaaaaggatgaaagggaaagtagc
cttcctaatggtcggagcgtctccctcatggacctccaggacactcatgctgctcaagtg
gagcatgcatctgtcatgcttgatgtgcctatacgcttgaccggaagccagctttccata
acccaggtggccagcatcaaacagctgcgggaaacccagagcactccccaaagtgcaccc
caagtgagaaggcccctgcacccagccttgaaccagccaggtggccttcagcccttgtcg
ttccagaaccctgtctatcacctcaataacccaattccagcaatgccaaaggcctctata
gattccagtttggagaacctaagcactgccagttccagaagccaaagtaacagtgaagac
ttcaagctcagtggacccagcaatagcagcatggaagatttcactaaacgtagcactcag
agtgaggacttctccaggcggcacacggtgccagatagacacatacctcttgctttgcca
cgacaaaatagtactgggcaggcccagatccgaaaagtggaccagggtgggttaggtgcc
cgagccaaagccccaccatccctgccacacagtgcttctttacgtagcaccgggagcatg
tcagtggtgtccgcagccctggtggccgaacctgtgcagaatgggagccggtcccggcag
cagtcctcttcctccagagagagccctgttcccaaagttagagcaatccagagacaacag
acacagcaggttcagtcacctgtggactctgccacaatgtccccagtagagaggacagca
gcctgggttctgaacaatgggcagtatgaagaggatgtggaagaaactgagcaaaatcta
gatgaagccaagcatgctgagaagtatgaacaagaaattactaaactgaaggagcgcctg
agagtttccagccggcgactggaggaatatgaacgccgcttgctggtgcaggagcagcag
atgcagaagctgctgctggaatacaaggcccgactggaggacagcgaggagcggctccga
agacagcaggaagaaaaagatagccagatgaaaagcatcatcagcaggctaatggctgtg
gaagaggaactgaagaaggatcatgctgagatgcaagcagttattgatgcaaagcagaaa
ataattgatgcacaggaaaaacggatcgtgtccctggattcagccaacaccagactgatg
agcgcgctgacccaagtgaaggagcggtacagcatgcaggtccgcaatggcatctccccc
accaaccccaccaagctttccatcacggagaatggtgaattcaaaaacagcagctgctga

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