KEGG   Homo sapiens (human): 100507436Help
Entry
100507436         CDS       T01001                                 

Gene name
MICA, MIC-A, PERB11.1
Definition
(RefSeq) MHC class I polypeptide-related sequence A
  KO
K07985  MHC class I-related protein
Organism
hsa  Homo sapiens (human)
Pathway
hsa04650  Natural killer cell mediated cytotoxicity
hsa05167  Kaposi's sarcoma-associated herpesvirus infection
Network
N00185  KSHV MIR2 to cell surface molecule-endocytosis
N00210  KSHV MIR1/2 to host-cell-protein inhibition
Disease
H00288  Familial Mediterranean fever (FMF)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    100507436 (MICA)
 Human Diseases
  Infectious diseases
   05167 Kaposi's sarcoma-associated herpesvirus infection
    100507436 (MICA)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: MHC_I C1-set Ig_3 TDH Ig_2
Motif
Other DBs
NCBI-GeneID: 100507436
NCBI-ProteinID: NP_000238
OMIM: 600169
HGNC: 7090
Ensembl: ENSG00000204520
Vega: OTTHUMG00000031073
Pharos: Q29983(Tbio)
UniProt: Q29983
Structure
PDB: 

Position
6p21.33
AA seq 383 aa AA seqDB search
MGLGPVFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGSVQSGFLTEVHLDGQPFLRCD
RQKCRAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIKDQKEGLHSLQEIRVCE
IHEDNSTRSSQHFYYDGELFLSQNLETKEWTMPQSSRAQTLAMNVRNFLKEDAMKTKTHY
HAMHADCLQELRRYLKSGVVLRRTVPPMVNVTRSEASEGNITVTCRASGFYPWNITLSWR
QDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSGNHSTHPVPSGKV
LVLQSHWQTFHVSAVAAAAIFVIIIFYVRCCKKKTSAAEGPELVSLQVLDQHPVGTSDHR
DATQLGFQPLMSDLGSTGSTEGA
NT seq 1152 nt NT seq  +upstreamnt  +downstreamnt
atggggctgggcccggtcttcctgcttctggctggcatcttcccttttgcacctccggga
gctgctgctgagccccacagtcttcgttataacctcacggtgctgtcctgggatggatct
gtgcagtcagggtttctcactgaggtacatctggatggtcagcccttcctgcgctgtgac
aggcagaaatgcagggcaaagccccagggacagtgggcagaagatgtcctgggaaataag
acatgggacagagagaccagagacttgacagggaacggaaaggacctcaggatgaccctg
gctcatatcaaggaccagaaagaaggcttgcattccctccaggagattagggtctgtgag
atccatgaagacaacagcaccaggagctcccagcatttctactacgatggggagctcttc
ctctcccaaaacctggagactaaggaatggacaatgccccagtcctccagagctcagacc
ttggccatgaacgtcaggaatttcttgaaggaagatgccatgaagaccaagacacactat
cacgctatgcatgcagactgcctgcaggaactacggcgatatctaaaatccggcgtagtc
ctgaggagaacagtgccccccatggtgaatgtcacccgcagcgaggcctcagagggcaac
attaccgtgacatgcagggcttctggcttctatccctggaatatcacactgagctggcgt
caggatggggtatctttgagccacgacacccagcagtggggggatgtcctgcctgatggg
aatggaacctaccagacctgggtggccaccaggatttgccaaggagaggagcagaggttc
acctgctacatggaacacagcgggaatcacagcactcaccctgtgccctctgggaaagtg
ctggtgcttcagagtcattggcagacattccatgtttctgctgttgctgctgctgctatt
tttgttattattattttctatgtccgttgttgtaagaagaaaacatcagctgcagagggt
ccagagctcgtgagcctgcaggtcctggatcaacacccagttgggacgagtgaccacagg
gatgccacacagctcggatttcagcctctgatgtcagatcttgggtccactggctccact
gagggcgcctag

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (2)   
   KEGG PATHWAY (2)   
Network (2)   
   KEGG NETWORK (2)   
Disease (2)   
   KEGG DISEASE (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   UniGene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (7)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (45)   
   RefSeq(nuc) (5)   
   GenBank (20)   
   EMBL (20)   
Protein domain (5)   
   Pfam (5)   
All databases (83)   

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