KEGG   Homo sapiens (human): 10126Help
Entry
10126             CDS       T01001                                 

Gene name
DNAL4, MRMV3, PIG27
Definition
(RefSeq) dynein axonemal light chain 4
  KO
K10412  dynein light chain 4, axonemal
Organism
hsa  Homo sapiens (human)
Pathway
hsa05016  Huntington disease
Disease
H01287  Congenital mirror movements
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09164 Neurodegenerative disease
   05016 Huntington disease
    10126 (DNAL4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    10126 (DNAL4)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    Dyneins
     10126 (DNAL4)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Dynein_light DUF3109 Ground-like
Motif
Other DBs
NCBI-GeneID: 10126
NCBI-ProteinID: NP_005731
OMIM: 610565
HGNC: 2955
Ensembl: ENSG00000100246
Vega: OTTHUMG00000151025
Pharos: O96015(Tdark)
UniProt: O96015
Position
22q13.1
AA seq 105 aa AA seqDB search
MGETEGKKDEADYKRLQTFPLVRHSDMPEEMRVETMELCVTACEKFSNNNESAAKMIKET
MDKKFGSSWHVVIGEGFGFEITHEVKNLLYLYFGGTLAVCVWKCS
NT seq 318 nt NT seq  +upstreamnt  +downstreamnt
atgggagaaacagaagggaagaaagatgaggctgattataagcgactgcagaccttccct
ctggtcaggcactcggacatgccagaggagatgcgcgtggagaccatggagctatgtgtc
acagcctgtgagaaattctccaacaacaacgagagcgccgccaagatgatcaaagagaca
atggacaagaagttcggctcctcctggcacgtggtgatcggcgagggctttgggtttgag
atcacccacgaggtgaagaacctcctctacctgtacttcgggggcaccctggctgtgtgc
gtctggaagtgctcctga

KEGG   Homo sapiens (human): 127602Help
Entry
127602            CDS       T01001                                 

Gene name
DNAH14, C1orf67, Dnahc14, HL-18, HL18
Definition
(RefSeq) dynein axonemal heavy chain 14
  KO
K10408  dynein heavy chain, axonemal
Organism
hsa  Homo sapiens (human)
Pathway
hsa05016  Huntington disease
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09164 Neurodegenerative disease
   05016 Huntington disease
    127602 (DNAH14)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    127602 (DNAH14)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    Dyneins
     127602 (DNAH14)
BRITE hierarchy
SSDB OrthologParalogGFIT
Other DBs
NCBI-GeneID: 127602
NCBI-ProteinID: NP_001138626
OMIM: 603341
HGNC: 2945
Ensembl: ENSG00000185842
Vega: OTTHUMG00000037447
Pharos: Q0VDD8(Tdark)
UniProt: Q0VDD8
Position
1q42.12
AA seq 453 aa AA seqDB search
METFIPIDLTTENQEMDKEETKTKPRLLRYEEKKYEDVKPLETQPAEIAEKETLEYKTVR
TFSESLKSEKTEDYLRESIIQQHMVSPEPASLKEKGKSRRKKDQTHACPNVRKARPVSYD
RTEPKDDDVIRNIIRLREKLGWQTILPQHSLKYGSSKIAIQKITLKKPLEDDGEFVYCLP
RKSPKSLYNPYDLQVVSAHTAKHCKEFWVITASFISKVINIVGSVKEVELIPTLEWLSER
RHYYLLRQFKIFSDFRMNKAFVTWKLNVKRIKTEKSRSFLYHHLFLADDLFQTCLVYIRG
LCEDAINLKNYNDHENNLSAICLVKLDSSRTYSLDEFCEEQLQQATQALKQLEDIRNKAI
SEMKSTFLKVAEKNEIKEYFESKLSEDDTTHFKLPKYRRLLETFFKFVMLVDYIFQELIR
QLMNTAVTLLLELFNGSAGMPFSVEKKNENLIR
NT seq 1362 nt NT seq  +upstreamnt  +downstreamnt
atggagacgtttatacccattgatttgacaactgaaaatcaagagatggacaaggaggaa
accaagacaaaaccaagacttttaagatatgaagagaaaaaatatgaagatgtgaaacca
ttagagactcaaccagctgaaatagcagaaaaggaaacattggaatataaaacagttaga
acattctctgaatctttgaagtcagagaaaacagaagattaccttagagaaagtataatt
caacaacatatggtttctccagagccagcttcccttaaggagaaagggaagtcaaggaga
aaaaaggatcaaactcatgcttgtccaaatgttaggaaagccaggcctgtgtcctatgat
agaacagaaccaaaagatgatgatgtgataagaaatattattaggctacgagaaaagctt
ggttggcaaactatattaccgcagcacagtttgaaatacggaagctccaaaattgcaatt
cagaagattactttaaagaaacctttggaagatgatggagaatttgtttattgccttcct
cggaaaagtcctaaatccctttacaatccatatgatcttcaggtagtatcggctcatact
gctaaacattgcaaagaattttgggttattactgcttcatttatctcaaaggttattaat
atagttggtagtgtaaaggaagtagaactcatacctactttggaatggctatcagaaaga
agacattactatttattacggcaattcaagatattttctgatttccgaatgaataaagca
tttgttacctggaaattgaatgttaaaagaattaagacagagaagagcaggtcatttttg
taccaccatctttttttggctgatgacttgtttcaaacctgtttggtttatataagagga
ctttgtgaagatgcaattaatctcaaaaattataatgaccatgaaaataatctatctgcc
atatgccttgtaaagctggatagttctcgaacatattctctagatgaattttgtgaagag
cagttacagcaagctacccaggcattgaaacaacttgaggacatcaggaataaagcaatt
tcagagatgaaaagtacttttctaaaggttgcagaaaagaatgaaatcaaagagtatttt
gagtcaaaactctctgaagatgacacaacacatttcaagctgcctaaatatagacgttta
ttagaaacatttttcaagtttgtaatgctggttgactacatatttcaggaactcattcgt
caacttatgaacactgcagtcacactacttttggaattatttaatggttctgctggaatg
ccattttcagtggaaaaaaagaatgaaaatcttatcaggtaa

KEGG   Homo sapiens (human): 146754Help
Entry
146754            CDS       T01001                                 

Gene name
DNAH2, DNAHC2, DNHD3
Definition
(RefSeq) dynein axonemal heavy chain 2
  KO
K10408  dynein heavy chain, axonemal
Organism
hsa  Homo sapiens (human)
Pathway
hsa05016  Huntington disease
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09164 Neurodegenerative disease
   05016 Huntington disease
    146754 (DNAH2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    146754 (DNAH2)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    Dyneins
     146754 (DNAH2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: AAA_6 DHC_N2 DHC_N1 AAA_8 Dynein_C AAA_9 AAA_7 AAA_lid_11 MT Dynein_heavy AAA_5 Dynein_AAA_lid AAA_lid_1 AAA AAA_22 AAA_16 TsaE T2SSE Mg_chelatase Sigma54_activat NB-ARC DUF3452 IstB_IS21 Sigma54_activ_2 AAA_2 DUF815 CbiA Bac_DnaA ATP_bind_1 cobW Guanylate_kin
Motif
Other DBs
NCBI-GeneID: 146754
NCBI-ProteinID: NP_065928
OMIM: 603333
HGNC: 2948
Ensembl: ENSG00000183914
Vega: OTTHUMG00000178020
Pharos: Q9P225(Tdark)
UniProt: Q9P225
Position
17p13.1
AA seq 4427 aa AA seqDB search
MSSKAEKKQRLSGRGSSQASWSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLE
GPQAQSEESVEPEADVKPLFLSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDP
CFGLKLELGMPVQTQNQLVYFIRQAPVPITWENFEATVQFGTVRGPYIPALLRLLGGVFA
PQIFANTGWPESIRNHFASHLHKFLACLTDTRYKLEGHTVLYIPAEAMNMKPEMVIKDKE
LVQRLETSMIHWTRQIKEMLSAQETVETGENLGPLEEIEFWRNRCMDLSGISKQLVKKGV
KHVESILHLAKSSYLAPFMKLAQQIQDGSRQAQSNLTFLSILKEPYQELAFMKPKDISSK
LPKLISLIRIIWVNSPHYNTRERLTSLFRKVCDCQYHFARWEDGKQGPLPCFFGAQGPQI
TRNLLEIEDIFHKNLHTLRAVRGGILDVKNTCWHEDYNKFRAGIKDLEVMTQNLITSAFE
LVRDVPHGVLLLDTFHRLASREAIKRTYDKKAVDLYMLFNSELALVNRERNKKWPDLEPY
VAQYSGKARWVHILRRRIDRVMTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVRKTFQ
EWTSSLDKDCIRRLDTPLLRISQEKAGMLDVNFDKSLLILFAEIDYWERLLFETPHYVVN
VAERAEDLRILRENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWALK
GASAFFITECRIHASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFEED
QREHRAAVQQKLMNLHQDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRLNV
KWSLLELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGNHL
FSTISVFCHLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQNYLKTWD
MYREIWEINKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCSHL
KFSLVQHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLVDA
LKHDLANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQMLKK
HKEKFKTGLIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMREEE
NSLRANLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTETM
ETTAHGLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQVR
DEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVTQL
DIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILEVI
EMILTVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTHHP
GLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPHLK
KCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMRVT
LRDLLRNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKILK
VMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFDWL
SQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGS
PKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRI
NIEVLSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPENLK
SMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRAL
TSLLRYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPVID
YGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQAS
LSSLCRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEKPD
EKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPATVS
RCGMVYTDYADLGWKPYVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPLPE
YSGITSLCKLYSALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRIDSY
LREIEGSFPNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRYNY
LVSSLVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIES
RVEKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQTIK
YIREMFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFEEE
VKPIGNVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKSSI
TRLWIHECFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFLKEP
KVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNMLL
VGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFIFV
DTQIADESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYLIE
RVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVDLG
TQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQEL
LAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADEQQ
KAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGRPP
AQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQPD
FQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEK
LREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGL
EEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFLCN
PTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIIDLQ
MSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYNTN
FRFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVIN
IAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEINT
DLAREAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDRID
YLNDYHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDREG
QMDNPCSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGEWE
NACNEMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLVFI
LSPGVDPTSALLQLAEHMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHLSL
SWMPNLDKLVEQLQVEDPHPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMTRL
YQLMSEPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSENL
LSLYLDEYEETPWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRLSA
LETYFIPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQPQI
TPTRAGGQTREEKVLELAADVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEIQRYNTLM
QTILFSLTDLEKGIQGLIVMSTSLEEIFNCIFDAHVPPLWGKAYPSQKPLAAWTRDLAMR
VEQFELWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDDSN
LVYPPKDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGMYS
CPCYYYPNRAGSSDRASFVIGIDLRSGAMTPDHWIKRGTALLMSLDS
NT seq 13284 nt NT seq  +upstreamnt  +downstreamnt
atgtccagcaaagctgagaagaagcagcgattgagtggccgaggaagctcccaggcaagc
tggtcagggcgggccactcgggctgctgtggccacacaggagcaggggaatgccccggct
gtcagtgagccagagctgcaggctgagctccccaaggaggagcctgagccacggttggag
ggacctcaagcacagagtgaagaatcagtggagcccgaggcagatgtgaagcccctcttc
ctttcccgagctgcgctgacaggactggcggatgcagtgtggacacaggagcatgatgcc
attctggaacactttgcccaggaccctacagaatccatcctcaccatcttcattgaccct
tgttttgggctgaagctagagctgggcatgcctgtacagacccagaaccagcttgtctac
ttcattcgccaagcaccagttcccatcacctgggagaacttcgaggcaactgtgcagttt
gggacggtgcggggcccctatatcccggccctgcttcggctgctcggtggagtctttgcc
cctcagatctttgcaaacacaggctggcctgagagcattagaaatcattttgcttctcat
ctgcacaagttcttggcctgcctgacagacactcggtacaaactggaggggcacacggtc
ctctacatccctgcagaggccatgaacatgaagcctgagatggtgataaaggacaaagag
ctggtgcaacggctagagacctccatgatccactggacccggcagataaaggagatgctc
agtgcccaggagactgtggagacaggagaaaatttaggtcctctggaggagattgagttc
tggcgcaaccgatgcatggacctgtctggcatcagtaagcagctggtgaagaagggagtg
aagcacgttgaatccatcctgcaccttgccaagtcgtcctacttggcgccctttatgaaa
ctggcacagcagatccaggatggctctcgtcaagcacagtcaaacctgacctttttgtca
atcctgaaggaaccttaccaggagttggctttcatgaagcccaaggacatctctagcaag
ctccctaagctgatcagtctcatccgcatcatctgggtcaactctccccactacaacact
cgggagagactgacctcgctcttccgaaaggtatgtgactgtcagtatcacttcgcccgc
tgggaagatggcaagcagggtccccttccttgcttctttggtgcccaggggccacagata
acacggaacttgctggagattgaggacatctttcataaaaatctgcacacgctgcgagcc
gttcgcgggggtatcctggatgtcaagaacacctgttggcatgaagactacaataagttc
cgtgccggaatcaaggacctggaggtgatgacccagaacctgatcacctcagccttcgag
ttggtgcgggacgtgccgcacggcgtgcttctgctggacaccttccacaggcttgcctcc
cgcgaggctatcaagcggacttatgacaagaaggcggtggatctctacatgctgttcaat
agcgagctggccctggtgaaccgtgaacggaacaagaaatggccagacctggagccctac
gtggcccagtattccggaaaggcgcgctgggtgcacatcctccggcgtcgcatcgacaga
gtcatgacctgccttgctggtgctcatttcctgccccgtattgggactggaaaggagagt
gtgcacacctatcagcagatggtccaggccattgatgagctggttcgaaaaaccttccaa
gagtggacatcaagtctggacaaggattgcattcggcggttggataccccattgctgcga
atcagccaggagaaggcgggcatgctggatgtcaactttgacaagtcccttctgattctc
tttgcggaaattgactactgggagcggctgctgtttgagacgccccattacgtggtgaac
gtagctgagcgagccgaggacctgcgcattctgcgtgaaaatctgctactcgttgctaga
gactacaataggattattgccatgctgtccccagatgagcaggccctattcaaagagcgt
attcggctcctggataagaagatccacccgggactcaagaaactgcactgggccttgaag
ggggccagtgccttcttcatcacggagtgccgtatacatgccagcaaggtgcagatgatt
gtgaatgagttcaaggcatccactctgaccattggctggcgagcccaagagatgtcagag
aagctgctggtacgcattagtggcaaacgggtatacagggacctggaatttgaagaggac
caaagagagcatcgggcagctgtacagcagaaattgatgaacctgcaccaggatgtggtg
accatcatgaccaactcctatgaggtcttcaagaatgatggtcctgagattcagcagcag
tggatgctgtacatgattcggctggaccgcatgatggaggatgccctgcgcctgaatgtg
aagtggtcactgctagaactatccaaggctatcaacggggatggaaagaccagcccaaac
ccactcttccaagtccttgtcattttgaagaatgatctgcaaggaagtgtggcacaggtg
gaattctcacccactctgcagactttggcaggtgtggtcaatgacattggcaaccacctc
ttttccaccatctctgtcttctgccacctccctgacattctcaccaagcgcaagttacat
cgtgaacccatccaaacagttgtggagcaagatgaggacatcaagaagatccagacccaa
atcagcagcggcatgactaacaacgcaagcctgctgcagaactacctcaagacctgggac
atgtaccgggagatctgggagatcaacaaggactccttcattcatcgctaccagcgcctc
aaccctcctgtctcttcttttgttgccgacattgcccgctacacggaagttgctaataac
gtgcagaaggaggagacagtcaccaacatccagtttgtgctgctggactgttcgcacctc
aagttctccctggtgcagcactgcaatgaatggcagaacaagttcgcgactctgctcagg
gagatggctgctgggcgcctcctggagctgcacacctacctgaaggagaacgcagagaaa
atcagccgccctccgcagacactggaggaactgggggtcagcttgcagctcgtggatgcc
ctgaagcacgacttggccaacgtggagactcagatccctcccatacacgagcaatttgcc
attcttgaaaagtacgaggtgccagtcgaggacagtgtcctggagatgctggacagtctc
aacggggagtgggttgtcttccaacaaactctgctggacagtaagcaaatgctgaagaaa
cacaaggagaaattcaagacaggcctgatccactcggcagatgacttcaagaagaaagca
catacacttctggaagatttcgaattcaaaggccatttcaccagcaacgtgggatacatg
tctgccttagaccagattacacaagtgcgggccatgctgatggccatgcgggaagaggaa
aatagtctccgagccaacctgggcatcttcaagatcgagcagccaccctccaaggacctt
cagaacctggagaaggagctcgatgccctccagcaaatctgggagatcgcacgagactgg
gaggagaactggaatgagtggaagactggccggttcctgatcctgcagacggaaaccatg
gagaccacggcccacgggctgtttcgtcgcctcacaaaattagccaaagagtataaggac
cgaaactgggaaattattgaaaccactcgctcaaaaatagagcagttcaagaggaccatg
cctctcatctcagacctgcggaaccctgcccttagagagaggcactgggaccaggtccgg
gatgagatccagcgggagtttgatcaggaatctgaaagcttcaccttggagcagattgtg
gagcttgggatggatcagcatgtggagaaaattggggagatctctgcttcagcaactaaa
gagctggctatagaagtggctttacaaaacattgccaagacctgggatgtgactcagctc
gacatagtaccctacaaggataagggccatcatcggctcagaggtacagaagaagtattc
caggcactggaagataaccaggtagctctgtctaccatgaaggcatcacgctttgtcaag
gcctttgagaaggatgtggaccactgggaacgctgcctctccctcattttggaggttatt
gagatgattctcacagtgcagcgtcagtggatgtacttagagaatatcttcctaggagaa
gacatccgcaagcagctgcccaatgaatcgaccttatttgaccaggtcaacagcaactgg
aaagccatcatggacaggatgaacaaggacaacaatgctctccggagcacccatcaccca
ggcctcctggacacattgatagaaatgaatacaatcctggaagatattcagaaatctctg
gatatgtatttagagaccaagcgacatattttcccccgcttctacttcttgtccaatgat
gacctgctggagattctgggccagtcccgaaacccagaggctgtgcagccacacctcaaa
aaatgctttgacaacatcaagttgctgagaatccagaaggttggagggcccagcagcaaa
tgggaagctgtggggatgttctcgggcgacggcgagtacattgacttcctccactcagta
tttttagaaggccctgtggagtcctggcttggcgatgtggaacagaccatgagggtgacc
ctgcgggaccttctccggaactgccacctggccctcaggaagttcctcaacaagagggac
aaatgggtgaaggagtgggctggccaggtggtgatcactgccagtcagatccagtggacg
gctgatgtcaccaagtgcctgctgacagcgaaggagcgggcagacaagaaaatcctcaag
gtcatgaagaagaaccaggtgtcaatcctgaataagtattcagaagccatcagggggaac
ttgaccaagatcatgcggcttaaaattgtggctctggtgacgatagaaattcatgcccgg
gatgtgttggagaagctttacaagagtggcctcatggatgtcaattcctttgactggctc
agccaacttcggttctactgggagaaggatcttgatgactgtgtcatccgccagaccaac
acgcaatttcagtataattatgagtacttgggtaactcgggccggctcgtcatcaccccc
ctgacggacaggtgttacatgacactgaccacggcattgcacctgcaccgagggggctcc
cccaaaggccctgcaggcacaggcaagaccgagaccgtcaaggacctgggcaaggccctg
ggcatatatgtcattgtggtcaactgctctgagggcctggactacaagtccatgggccga
atgtactcaggtctggcccagactggagcttggggctgctttgatgagtttaaccgcatc
aacatcgaggtgctgtcagtggtggcccaccagatcctgtgcatcctgtctgccctggct
gccggcctcacccatttccattttgatggctttgaaataaatctggtgtggtcctgtggg
atcttcattaccatgaatcctggctatgctggccgcacagagcttcccgaaaatcttaaa
tccatgttccgcccaattgccatggtggtgcctgactccaccctcattgcagaaatcatt
ctctttggagagggctttggcaactgcaagattctggccaagaaggtgtacacactctac
tcactggctgtgcagcagctgtccagacaggaccactatgactttggcctgcgtgccctc
acctcccttctgcgctatgctggcaagaagcgccgcctacagccggatctgactgatgaa
gaggttctgctgctctcaatgagagatatgaacatcgccaagctcacttcagttgatgca
cccctgttcaatgccatcgtgcaagatctgtttcccaacattgagctgcctgtcattgac
tatggcaagctgcgggagaccgttgagcaggagattcgagacatgggcctgcaaagcacg
ccgttcaccctcaccaaggttttccagttgtatgaaaccaagaactcccgccactccacc
atgatcgtgggctgcacgggcagcggcaagactgcctcatggcgcattctacaggcctcc
ctgtcctctctgtgccgcgccggagaccctaacttcaacattgttagagagttccctttg
aaccccaaggcattgtccctaggggaactgtatggggaatatgacctcagcaccaatgaa
tggacagatggcatcttgtccagtgtcatgcggacggcatgtgcagatgagaaacccgac
gagaagtggatcctgttcgatggccccgtggacacactgtggatcgagaacatgaactcc
gtcatggacgataacaaggtgttgaccctcatcaacggcgagcgcatcgcgatgcccgag
caggtgtctctcctgtttgaagtggaggacctggcaatggcctctccggccactgtatcc
cgctgcgggatggtctacactgactacgctgacctgggctggaagccctatgttcagtca
tggctggagaagaggccaaaggctgaggtggagccccttcaacgcatgttcgaaaagctc
atcaacaagatgctggcctttaagaaggacaactgcaaggagctggtgcccctgcccgag
tacagcggtatcacctccctctgcaagctgtactctgccctggccacgccagagaatggg
gtgaacccagctgacggcgagaactatgtcaccatggtagagatgacatttgtgttcagc
atgatctggtctgtgtgtgcctctgtggatgaggagggccggaagaggatcgacagctac
ctccgagagatcgagggctcctttcccaataaggacacggtatatgagtattttgtggac
cccaaaatacggagttggacatcatttgaggacaagctccctaagagttggcgctaccct
ccaaacgcccccttctataagatcatggtgcccaccgtcgacactgttcgctacaactac
ctggtgagcagcttggtggccaaccagaatcccattctgctggtgggtcccgtggggact
gggaagacctccatcgcccagagcgttctgcagtccctgccctccagccagtggtcggtg
ctcgttgtcaacatgtccgcacagaccacatccaataacgtgcagagcatcattgagagc
agggttgagaagcgaaccaagggtgtctacgtgccattcgggggcaaaagcatgatcacc
tttatggatgacctaaatatgcccgctaaggacatgtttgggtcccagccacccctggag
ctgatccgcctctggattgactatggcttctggtatgaccgtacgaagcagaccatcaag
tacattcgagaaatgttcctgatggctgccatgggcccccctgggggtggacggactgtc
atctccccaaggctacggagtcgcttcaacattatcaacatgaccttccccacaaagtcc
cagatcatccgcatattcggcaccatgatcaatcagaagcttcaggactttgaggaagag
gtgaagcccattgggaacgtggtgacagaggccaccctggacatgtacaacaccgtggta
cagcgcttcctgcccacgcccaccaagatgcattacctcttcaaccttcgagacatctcc
aaggtgttccagggcatgcttagagccaacaaggacttccatgataccaagtccagcatc
acacggctctggatccatgaatgtttcagagtcttctctgaccggctggttgatgcggca
gacacagaagccttcatgggcatcataagcgacaagctcggctccttctttgacctcaca
tttcatcatctctgtcccagcaagcgtcctcctatctttggggatttcctgaaggagccc
aaggtgtatgaagacctcacggatctgacagtgctgaagacagtcatggagacagctcta
aatgagtataacctgtcaccctctgtcgtgcccatgcagctagtgctcttccgagaggct
attgaacacatcacacggatcgtgcgggtcattggacagcctcggggcaacatgctcctg
gtgggtatcgggggcagcggacgccagagtctggcccgcctggcttcatccatctgcgac
tacaccaccttccagatcgaggtcaccaaacattatcggaagcaggagttccgagatgat
atcaagcgtctgtatcgccaggctggggtggagctcaagaccacgtccttcatttttgtg
gacacccaaatagctgatgagtccttcctagaggacatcaacaacatcctcagctcaggc
gaggtgcccaatctctacaagcctgatgaatttgaagagatccagtcgcatatcatagac
caggcccgggtggagcaggtgcctgagtcatcggacagcctcttcgcctacctcattgaa
cgcgtgcagaacaacctgcacatcgtgctctgcctcagccccatgggggatcccttcagg
aactggatccgccagtacccagccttggtgaactgcacaaccatcaactggttctcagag
tggccccaagaggccctgctcgaggtggctgagaagtgcctcataggagtagacctggga
actcaggagaatatccacaggaaggtggcccagatctttgtcactatgcactggtcagta
gctcagtattcccagaagatgctgttggaactgcggagacacaactatgtcacacccacc
aaatacctggaactcctgtctggatataagaagttgctgggagaaaaacggcaggagctg
ctggcccaagccaataaactgcggacaggcttgttcaagatcgacgaaactagggaaaag
gtgcaagtgatgtcgttggagctggaggatgccaagaagaaggtggctgagttccagaag
cagtgtgaggagtacctggtcatcattgtgcagcagaagcgggaggcagatgagcagcag
aaggccgtaacagccaacagtgaaaagattgcagttgaggaaatcaagtgtcaggcactg
gctgacaatgcccagaaagatctagaagaggcactgcccgccctggaagaggccatgcgg
gccctggagtctctgaacaagaaggatataggagagatcaagtcttatggacggccccca
gcccaagtggagatagtgatgcaggcagttatgattcttcgaggcaacgagcccacatgg
gcagaggccaagaggcagctaggggaacagaacttcatcaagtcactgatcaactttgat
aaagacaatatctcagataaggttctgaagaagattggggcctactgcgcccagcctgac
ttccagcctgatatcatcggccgcgtctccctggctgccaagtccctctgcatgtgggtg
cgggccatggagctgtatgggcggctatatcgggtggtggagcccaagcgaatccgaatg
aacgctgccttggctcagcttcgggagaagcaagccgcgctcgctgaggcccaggagaag
ctgcgggaggtagctgagaaactggagatgctaaagaaacagtatgatgagaagctggca
cagaaggaggagcttcgcaagaagtctgaagagatggagctgaagctggagcgagctggg
atgctcgtgtcggggttggctggcgagaaggccagatgggaggagacagtccagggcctg
gaggaggacctgggctacctggtgggggactgtctcctggcagctgccttcctgtcctac
atgggacccttcctgaccaactaccgggatgagattgtcaaccaaatctggatcgggaag
atctgggagcttcaggttccttgctccccttctttcgccatcgataacttcctgtgcaat
cctaccaaagtccgggactggaacatccaagggttgccctcagacgccttctccactgag
aatggcatcatcgtcacccgaggcaacaggtgggcactgatgatcgaccctcaggcccag
gccctgaaatggattaagaacatggaaggaggccagggcctgaagatcatcgacctgcag
atgagcgattacctgcgaatcctagaacacgccattcactttggatacccggtgctactt
cagaacgtgcaggaatatctggaccccacactgaaccccatgctcaacaaatctgtagcc
cgaatcggtggtcggctgttgatgcgcattggcgataaggaggtggaatataataccaat
ttccgtttctacatcaccaccaagctctccaacccccactacagcccagagacctcagcc
aagaccaccatcgtcaactttgctgttaaagaacagggcctggaggcccagctgctgggc
attgtggtgcggaaggagcggcctgagctggaggagcagaaggactcactggtcatcaac
atcgcggctggtaaaaggaagctcaaggagctggaggatgagatcctgcggctgctgaat
gaggccaccggctccctgctggatgatgtgcagctggtgaacacgctgcatacctccaag
atcacagccacagaggtgactgagcagctggagaccagtgagaccacagagatcaacact
gacttggcgcgggaggcttaccgcccatgcgcccagcgggcatcaatcctgttcttcgtg
ctcaatgatatgggctgcatcgaccccatgtaccagttctcactggatgcctacatcagc
ctctttattctcagcattgacaaaagccaccgcagcaataagctggaggaccgcattgac
tacctgaatgactaccacacctacgctgtctacaggtacacctgccgtacccttttcgaa
cgccacaaactactattcagttttcatatgtgtgccaaaatcttggagacttctggcaag
ctcaacatggatgaatacaacttctttctacgtgggggtgtggtcttggatcgggagggc
caaatggacaatccatgtagtagctggcttgcagatgcctactgggataacatcacagag
ctagacaaactgaccaacttccacggactcatgaactcctttgagcagtaccctcgtgac
tggcacctgtggtataccaatgctgccccggagaaggcgatgctgccaggtgagtgggaa
aatgcctgcaatgaaatgcaacggatgctgatcgttcgctccctgcgccaggaccgcgtg
gccttctgcgtgacctccttcatcatcaccaaccttggctcccgcttcatcgagccgcct
gtgctgaatatgaagtcggtgctggaggattcaaccccacgatccccactcgtgttcatc
ctgtcccctggtgtggaccccaccagtgccctgctgcagctggcagagcacatgggcatg
gcccagcgcttccacgccctgtccctgggccagggccaggcccccatcgctgctcggctc
ctccgagagggtgtgactcagggacactgggtgttcctggcaaactgccacctgtcactg
tcttggatgcctaatctggacaagctggtggagcagctgcaggtggaggatcctcatcca
tccttccgcctctggctcagctccatcccccacccagacttccctatctcaatcttgcag
gtcagcatcaagatgaccacagagccaccaaagggcctaaaggccaacatgacacgtctt
taccaactgatgtcagaaccacagttttcccgctgctccaaacctgccaaatataagaag
ctgctgttttcactctgtttcttccactctgtgttacttgaacgcaaaaagttcctgcag
cttggctggaacatcatctatggcttcaatgactccgactttgaggtgtcagaaaacttg
ctgagcctctatctcgatgagtacgaggagacaccttgggacgcacttaagtacctcatt
gccggcatcaactatggtggacatgtcacagatgactgggaccggcgcctgctgaccacc
tacatcaatgattatttctgtgaccagtctctatcaactcccttccaccggttgtcagca
ctggagacttatttcatccccaaggatggcagcctcgcttcttacaaggaatacatcagc
ttattgcctggcatggacccccctgaggcctttggccagcaccccaatgctgatgtggcc
tctcagatcactgaggcacaaaccctctttgatactttgctttccttgcaacctcagatt
acacccaccagggctggaggccagacccgggaagagaaggtccttgagttggccgctgat
gtgaagcagaagatccctgaaatgatcgactatgaggggactcaaaaactgctagctctc
gacccctcccccctcaatgtggtccttctgcaggagatccagagatacaacacactgatg
cagaccatcctgttctcactgacagacctagagaaaggcatccagggtctcatcgtcatg
tctacaagcctggaagagattttcaattgcatctttgatgcccatgttcctccgctctgg
ggaaaggcatacccctcacaaaagccattggctgcctggacccgggacttggccatgcgt
gtggagcagtttgagctgtgggccagccgggcccggcctcctgtgatcttctggttgtct
ggtttcacctttcccactggcttcctcactgctgtgctgcagtcttcagctcgccaaaac
aacgtttcagtggacagcctctcctgggagtttatcgtttccactgtggatgacagcaac
ctagtgtatccccccaaggatggtgtctgggtccggggcctgtacctggaaggtgctggc
tgggaccggaagaactcctgcttggtggaggcagagcccatgcagcttgtctgcctcatg
cccacgatccacttccggcctgcagagagccgcaagaagagcgccaagggcatgtactcc
tgcccctgctattactatcccaaccgggcaggcagctcagaccgagcctcctttgtcatc
ggcattgacctgcggtctggggccatgacacctgatcattggatcaagaggggcactgct
ctactcatgagcctggacagctga

KEGG   Homo sapiens (human): 1767Help
Entry
1767              CDS       T01001                                 

Gene name
DNAH5, CILD3, DNAHC5, HL1, KTGNR, PCD
Definition
(RefSeq) dynein axonemal heavy chain 5
  KO
K10408  dynein heavy chain, axonemal
Organism
hsa  Homo sapiens (human)
Pathway
hsa05016  Huntington disease
Disease
H00564  Primary ciliary dyskinesia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09164 Neurodegenerative disease
   05016 Huntington disease
    1767 (DNAH5)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    1767 (DNAH5)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    Dyneins
     1767 (DNAH5)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: DHC_N1 AAA_6 DHC_N2 Dynein_C AAA_8 AAA_9 AAA_7 AAA_lid_11 MT Dynein_heavy AAA_5 AAA_lid_1 Dynein_AAA_lid AAA_33
Motif
Other DBs
NCBI-GeneID: 1767
NCBI-ProteinID: NP_001360
OMIM: 603335
HGNC: 2950
Ensembl: ENSG00000039139
Vega: OTTHUMG00000090533
Pharos: Q8TE73(Tbio)
UniProt: Q8TE73
Position
5p15.2
AA seq 4624 aa AA seqDB search
MFRIGRRQLWKHSVTRVLTQRLKGEKEAKRALLDARHNYLFAIVASCLDLNKTEVEDAIL
EGNQIERIDQLFAVGGLRHLMFYYQDVEEAETGQLGSLGGVNLVSGKIKKPKVFVTEGND
VALTGVCVFFIRTDPSKAITPDNIHQEVSFNMLDAADGGLLNSVRRLLSDIFIPALRATS
HGWGELEGLQDAANIRQEFLSSLEGFVNVLSGAQESLKEKVNLRKCDILELKTLKEPTDY
LTLANNPETLGKIEDCMKVWIKQTEQVLAENNQLLKEADDVGPRAELEHWKKRLSKFNYL
LEQLKSPDVKAVLAVLAAAKSKLLKTWREMDIRITDATNEAKDNVKYLYTLEKCCDPLYS
SDPLSMMDAIPTLINAIKMIYSISHYYNTSEKITSLFVKVTNQIISACKAYITNNGTASI
WNQPQDVVEEKILSAIKLKQEYQLCFHKTKQKLKQNPNAKQFDFSEMYIFGKFETFHRRL
AKIIDIFTTLKTYSVLQDSTIEGLEDMATKYQGIVATIKKKEYNFLDQRKMDFDQDYEEF
CKQTNDLHNELRKFMDVTFAKIQNTNQALRMLKKFERLNIPNLGIDDKYQLILENYGADI
DMISKLYTKQKYDPPLARNQPPIAGKILWARQLFHRIQQPMQLFQQHPAVLSTAEAKPII
RSYNRMAKVLLEFEVLFHRAWLRQIEEIHVGLEASLLVKAPGTGELFVNFDPQILILFRE
TECMAQMGLEVSPLATSLFQKRDRYKRNFSNMKMMLAEYQRVKSKIPAAIEQLIVPHLAK
VDEALQPGLAALTWTSLNIEAYLENTFAKIKDLELLLDRVNDLIEFRIDAILEEMSSTPL
CQLPQEEPLTCEEFLQMTKDLCVNGAQILHFKSSLVEEAVNELVNMLLDVEVLSEEESEK
ISNENSVNYKNESSAKREEGNFDTLTSSINARANALLLTTVTRKKKETEMLGEEARELLS
HFNHQNMDALLKVTRNTLEAIRKRIHSSHTINFRDSNSASNMKQNSLPIFRASVTLAIPN
IVMAPALEDVQQTLNKAVECIISVPKGVRQWSSELLSKKKIQERKMAALQSNEDSDSDVE
MGENELQDTLEIASVNLPIPVQTKNYYKNVSENKEIVKLVSVLSTIINSTKKEVITSMDC
FKRYNHIWQKGKEEAIKTFITQSPLLSEFESQILYFQNLEQEINAEPEYVCVGSIALYTA
DLKFALTAETKAWMVVIGRHCNKKYRSEMENIFMLIEEFNKKLNRPIKDLDDIRIAMAAL
KEIREEQISIDFQVGPIEESYALLNRYGLLIAREEIDKVDTLHYAWEKLLARAGEVQNKL
VSLQPSFKKELISAVEVFLQDCHQFYLDYDLNGPMASGLKPQEASDRLIMFQNQFDNIYR
KYITYTGGEELFGLPATQYPQLLEIKKQLNLLQKIYTLYNSVIETVNSYYDILWSEVNIE
KINNELLEFQNRCRKLPRALKDWQAFLDLKKIIDDFSECCPLLEYMASKAMMERHWERIT
TLTGHSLDVGNESFKLRNIMEAPLLKYKEEIEDICISAVKERDIEQKLKQVINEWDNKTF
TFGSFKTRGELLLRGDSTSEIIANMEDSLMLLGSLLSNRYNMPFKAQIQKWVQYLSNSTD
IIESWMTVQNLWIYLEAVFVGGDIAKQLPKEAKRFSNIDKSWVKIMTRAHEVPSVVQCCV
GDETLGQLLPHLLDQLEICQKSLTGYLEKKRLCFPRFFFVSDPALLEILGQASDSHTIQA
HLLNVFDNIKSVKFHEKIYDRILSISSQEGETIELDKPVMAEGNVEVWLNSLLEESQSSL
HLVIRQAAANIQETGFQLTEFLSSFPAQVGLLGIQMIWTRDSEEALRNAKFDKKIMQKTN
QAFLELLNTLIDVTTRDLSSTERVKYETLITIHVHQRDIFDDLCHMHIKSPMDFEWLKQC
RFYFNEDSDKMMIHITDVAFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMSMGGAPAG
PAGTGKTETTKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIDLP
VLSVAAQQISIILTCKKEHKKSFIFTDGDNVTMNPEFGLFLTMNPGYAGRQELPENLKIN
FRSVAMMVPDRQIIIRVKLASCGFIDNVVLARKFFTLYKLCEEQLSKQVHYDFGLRNILS
VLRTLGAAKRANPMDTESTIVMRVLRDMNLSKLIDEDEPLFLSLIEDLFPNILLDKAGYP
ELEAAISRQVEEAGLINHPPWKLKVIQLFETQRVRHGMMTLGPSGAGKTTCIHTLMRAMT
DCGKPHREMRMNPKAITAPQMFGRLDVATNDWTDGIFSTLWRKTLRAKKGEHIWIILDGP
VDAIWIENLNSVLDDNKTLTLANGDRIPMAPNCKIIFEPHNIDNASPATVSRNGMVFMSS
SILDWSPILEGFLKKRSPQEAEILRQLYTESFPDLYRFCIQNLEYKMEVLEAFVITQSIN
MLQGLIPLKEQGGEVSQAHLGRLFVFALLWSAGAALELDGRRRLELWLRSRPTGTLELPP
PAGPGDTAFDYYVAPDGTWTHWNTRTQEYLYPSDTTPEYGSILVPNVDNVRTDFLIQTIA
KQGKAVLLIGEQGTAKTVIIKGFMSKYDPECHMIKSLNFSSATTPLMFQRTIESYVDKRM
GTTYGPPAGKKMTVFIDDVNMPIINEWGDQVTNEIVRQLMEQNGFYNLEKPGEFTSIVDI
QFLAAMIHPGGGRNDIPQRLKRQFSIFNCTLPSEASVDKIFGVIGVGHYCTQRGFSEEVR
DSVTKLVPLTRRLWQMTKIKMLPTPAKFHYVFNLRDLSRVWQGMLNTTSEVIKEPNDLLK
LWKHECKRVIADRFTVSSDVTWFDKALVSLVEEEFGEEKKLLVDCGIDTYFVDFLRDAPE
AAGETSEEADAETPKIYEPIESFSHLKERLNMFLQLYNESIRGAGMDMVFFADAMVHLVK
ISRVIRTPQGNALLVGVGGSGKQSLTRLASFIAGYVSFQITLTRSYNTSNLMEDLKVLYR
TAGQQGKGITFIFTDNEIKDESFLEYMNNVLSSGEVSNLFARDEIDEINSDLASVMKKEF
PRCLPTNENLHDYFMSRVRQNLHIVLCFSPVGEKFRNRALKFPALISGCTIDWFSRWPKD
ALVAVSEHFLTSYDIDCSLEIKKEVVQCMGSFQDGVAEKCVDYFQRFRRSTHVTPKSYLS
FIQGYKFIYGEKHVEVRTLANRMNTGLEKLKEASESVAALSKELEAKEKELQVANDKADM
VLKEVTMKAQAAEKVKAEVQKVKDRAQAIVDSISKDKAIAEEKLEAAKPALEEAEAALQT
IRPSDIATVRTLGRPPHLIMRIMDCVLLLFQRKVSAVKIDLEKSCTMPSWQESLKLMTAG
NFLQNLQQFPKDTINEEVIEFLSPYFEMPDYNIETAKRVCGNVAGLCSWTKAMASFFSIN
KEVLPLKANLVVQENRHLLAMQDLQKAQAELDDKQAELDVVQAEYEQAMTEKQTLLEDAE
RCRHKMQTASTLISGLAGEKERWTEQSQEFAAQTKRLVGDVLLATAFLSYSGPFNQEFRD
LLLNDWRKEMKARKIPFGKNLNLSEMLIDAPTISEWNLQGLPNDDLSIQNGIIVTKASRY
PLLIDPQTQGKIWIKNKESRNELQITSLNHKYFRNHLEDSLSLGRPLLIEDVGEELDPAL
DNVLERNFIKTGSTFKVKVGDKEVDVLDGFRLYITTKLPNPAYTPEISARTSIIDFTVTM
KGLEDQLLGRVILTEKQELEKERTHLMEDVTANKRRMKELEDNLLYRLTSTQGSLVEDES
LIVVLSNTKRTAEEVTQKLEISAETEVQINSAREEYRPVATRGSILYFLITEMRLVNEMY
QTSLRQFLGLFDLSLARSVKSPITSKRIANIIEHMTYEVYKYAARGLYEEHKFLFTLLLT
LKIDIQRNRVKHEEFLTLIKGGASLDLKACPPKPSKWILDITWLNLVELSKLRQFSDVLD
QISRNEKMWKIWFDKENPEEEPLPNAYDKSLDCFRRLLLIRSWCPDRTIAQARKYIVDSM
GEKYAEGVILDLEKTWEESDPRTPLICLLSMGSDPTDSIIALGKRLKIETRYVSMGQGQE
VHARKLLQQTMANGGWALLQNCHLGLDFMDELMDIIIETELVHDAFRLWMTTEAHKQFPI
TLLQMSIKFANDPPQGLRAGLKRTYSGVSQDLLDVSSGSQWKPMLYAVAFLHSTVQERRK
FGALGWNIPYEFNQADFNATVQFIQNHLDDMDVKKGVSWTTIRYMIGEIQYGGRVTDDYD
KRLLNTFAKVWFSENMFGPDFSFYQGYNIPKCSTVDNYLQYIQSLPAYDSPEVFGLHPNA
DITYQSKLAKDVLDTILGIQPKDTSGGGDETREAVVARLADDMLEKLPPDYVPFEVKERL
QKMGPFQPMNIFLRQEIDRMQRVLSLVRSTLTELKLAIDGTIIMSENLRDALDCMFDARI
PAWWKKASWISSTLGFWFTELIERNSQFTSWVFNGRPHCFWMTGFFNPQGFLTAMRQEIT
RANKGWALDNMVLCNEVTKWMKDDISAPPTEGVYVYGLYLEGAGWDKRNMKLIESKPKVL
FELMPVIRIYAENNTLRDPRFYSCPIYKKPVRTDLNYIAAVDLRTAQTPEHWVLRGVALL
CDVK
NT seq 13875 nt NT seq  +upstreamnt  +downstreamnt
atgtttaggattgggaggagacagctctggaagcatagcgtcactcgagttttaacgcaa
agactgaagggagagaaggaagccaagcgggctcttttggatgcgaggcataactactta
tttgcaattgtggcttcctgtttggacctgaacaaaaccgaagtggaggatgccattctt
gaagggaatcagattgaaagaattgatcaactttttgctgttggaggtctccgacacctc
atgttttactatcaagatgtggaggaagcagaaacaggacaacttggctctctaggaggg
gtaaatcttgtttctggaaagattaaaaaacctaaggtgttcgtgaccgagggaaacgat
gtggctcttactggggtatgtgtgttcttcatcaggactgacccttccaaagccatcacc
cctgacaacatccaccaggaggtgagttttaacatgttagatgcggcagatggaggcctg
ctcaacagtgtgagacgtttgctgtcggacatcttcattcctgctctcagagccacgagc
catggctggggcgagctcgagggccttcaggacgcagctaacattcgccaggagttcttg
agctccctggaaggctttgtgaacgtcctgtcgggtgcacaggagagtctgaaggagaag
gtgaaccttcgaaagtgtgacatacttgaactgaaaaccctaaaggaacctacggactac
ttgactctagcaaataaccctgagactttgggaaaaatagaggattgcatgaaagtatgg
atcaaacagacagaacaggttcttgctgaaaacaatcagctgctgaaggaagcggatgac
gttgggccacgagcggagctggagcactggaaaaaaagactctccaagtttaactacctt
ttggaacaattgaaaagcccggatgtgaaggctgtgctggcagtgcttgcggcggccaag
tcgaaactgctgaagacttggcgggagatggatattcgaatcactgatgcaactaatgaa
gcaaaggacaatgtgaaatacttgtatacacttgaaaaatgttgtgaccctttgtacagc
agtgatcccctatccatgatggatgctattcctacacttataaatgcaattaaaatgatc
tatagtatctctcattactataatacctctgagaagatcacatctctgtttgtaaaggtg
acaaatcagattatatctgcatgtaaagcctatattaccaataatggaaccgcttccatc
tggaaccagccacaggatgttgttgaagaaaaaatactatctgcgattaaactgaaacag
gaataccagctctgctttcacaagacaaaacaaaagcttaaacaaaatccaaatgcaaaa
caatttgattttagcgagatgtatatttttggaaaattcgaaacttttcaccgacgcctt
gccaagataatagacatctttacaaccctcaagacgtattcagtcctgcaagattccaca
attgaagggctggaagacatggccactaaataccagggcattgtggcaaccataaagaaa
aaggaatacaatttcctagaccagcggaaaatggattttgaccaagattacgaagagttt
tgcaagcagactaatgaccttcataacgagttgcggaagttcatggatgttacatttgca
aagattcaaaacacaaatcaagctctaagaatgttgaagaaatttgaaagattgaatata
cctaatcttggtattgatgacaaatatcaacttatccttgagaactatggggctgacatt
gatatgatttcaaagctgtatacaaagcagaaatacgatcctcctctggctcgaaaccag
cctcccatcgctggaaagattttgtgggcccgccagctcttccataggattcagcagccc
atgcagcttttccagcagcacccagctgtgctaagcacggcagaagccaaacctataatt
cgcagttacaacaggatggccaaggtcctcctggagtttgaggtcctcttccacagggcg
tggcttcggcaaattgaagaaattcatgtaggtcttgaggcttcattattggtgaaggct
ccaggcacaggggaattgtttgtaaactttgaccctcagatattaatcttatttagagaa
acagagtgcatggcccagatgggtctggaagtctctccactggcaacttccctcttccag
aaacgagatagatacaaaaggaacttcagtaacatgaagatgatgctagctgaatatcag
agagtgaagtcaaaaatacctgctgccattgagcaattgattgtccctcacttggccaaa
gtggatgaagctctccaacctggcttggctgcactgacctggacatcactgaatattgag
gcttatttagaaaacacttttgcaaagatcaaggacctggagttgctgcttgacagggtc
aatgatttgattgagttccgcattgatgccattctagaagaaatgagcagcacgcctctt
tgtcagcttccccaggaggagccactaacctgtgaagagtttctccaaatgacaaaggat
ctttgtgtaaatggtgcacaaatactacattttaaaagctcattagtggaggaggcagtc
aatgagcttgtaaatatgttgctggatgtggaagttttatctgaagaagaaagtgaaaaa
atatccaatgagaatagtgttaattacaaaaatgaaagttcagcaaaaagagaagaagga
aattttgacaccttgacatcatctattaatgccagggccaatgccctgcttttgacgaca
gtcacgaggaaaaagaaagaaactgagatgttaggggaagaagcccgcgagttactctct
catttcaaccatcagaacatggatgctcttctgaaagttacaaggaatacactagaggcc
attcgcaaacgtattcattcctctcacacaattaacttccgggacagtaacagtgcctct
aacatgaagcagaacagtttgcccattttccgggcaagcgtcactctggccattcccaac
atcgtcatggcccctgccctggaagatgtacagcagaccctgaacaaagccgtggagtgc
atcatcagtgtccctaagggggtcagacagtggagcagtgaactgttgtccaagaaaaag
atacaagaaagaaaaatggctgctttgcagagtaatgaagacagtgattctgatgttgaa
atgggagaaaatgaacttcaagataccttggagatagcatctgtaaatttacccattccc
gtgcaaaccaagaactattataagaatgtttctgaaaacaaagagattgtaaaattagtt
tctgtgcttagcacaattatcaactccaccaaaaaggaagttattacatccatggattgc
ttcaaacgctacaatcacatttggcaaaagggaaaagaagaagccattaagacatttatt
acacagagccccttgctttctgaatttgagtcccagattctctatttccaaaacctagag
caggaaattaatgctgagcctgaatatgtctgtgtgggttccattgctctgtacacagct
gacttgaagttcgccctgactgctgagacaaaggcctggatggttgtcattggacgccac
tgtaacaaaaaataccggagtgagatggaaaacatttttatgcttattgaagaattcaat
aagaaactaaatcgtccaattaaggacctagatgatattcggattgcaatggcagcgctg
aaagaaataagggaggagcaaatctccattgactttcaagtaggacctattgaggaatct
tatgccctgcttaacagatatggacttctgatagcaagggaagagatagacaaagttgat
acactgcactatgcttgggagaagctgctggcacgtgctggcgaagtccagaataaatta
gtctcactgcagcccagtttcaagaaagagcttattagtgctgtggaggtattcctccaa
gattgtcaccagttttatctggactatgatttgaatggtccaatggctagcggcttgaag
ccccaggaagccagtgacaggcttatcatgtttcagaatcaatttgataatatctatcgg
aaatacatcacatatactggaggagaggagctttttggcctgccagctacacagtatcct
cagcttcttgaaataaagaagcaactaaatcttctacagaaaatatatactctgtacaac
agtgtcatagaaactgtaaatagctattatgatattctttggtcagaggtgaatattgaa
aaaattaacaatgaactcttagaattccagaacagatgtcgaaagcttccccgggccttg
aaggactggcaggcttttttggacctgaagaagatcattgatgatttcagcgagtgttgc
ccgctgctggaatacatggccagtaaagccatgatggagcggcactgggaaaggataacc
accctcaccgggcacagtctggatgtggggaatgaaagctttaagttaagaaatatcatg
gaggcacctcttctgaaatataaagaggaaatagaggacatctgtatcagtgcggtgaaa
gagagagacattgagcaaaagctgaagcaagtgattaatgaatgggacaataaaacattc
accttcggcagctttaaaacccgtggagagctcctcttgagaggagacagtacctcggaa
atcatcgccaacatggaggacagcttgatgttgctgggatccctactgagcaacaggtac
aatatgccattcaaagcccagattcaaaaatgggtgcagtacctttccaactcaacagac
atcatcgagagctggatgacggtgcaaaacctgtggatttatttagaagctgtctttgtg
ggaggagacattgccaagcagctgcccaaggaagccaagcggttttctaacatagataaa
tcttgggtgaagatcatgactcgggcacatgaagtgcccagtgtagtccagtgctgtgtt
ggagatgagaccctggggcagctgttaccacacttgctggaccagttggaaatatgccag
aaatcccttactgggtacttggagaaaaaacgactgtgctttcctcggtttttcttcgtc
tcagatcctgcccttctagagattctggggcaggcgtcggactcccacactatacaggcc
catttgctgaatgtgtttgacaacattaaatctgtcaagttccacgaaaagatctatgat
cgaattctgtcaatttcctctcaagagggtgagacgattgaattggataaacctgtcatg
gcagagggcaatgtggaagtttggcttaattctcttttggaagaatctcagtcctcattg
catcttgtgattcgccaggcagccgcaaatattcaagaaacaggtttccaactaactgaa
tttctttcatccttccctgctcaggttggattattaggaattcagatgatatggacacgg
gattcagaagaagcccttagaaatgccaagtttgataaaaaaatcatgcagaaaactaat
caggctttcctggagctactcaatacattgatagacgtcaccacgagggatctgagttcc
acggaacgagtgaaatacgagactctgattactattcatgtgcaccaaagggatatcttt
gatgacctgtgtcatatgcatatcaagagtcccatggactttgagtggctgaaacagtgc
agattttactttaacgaagattctgacaagatgatgattcacatcacagatgtggcgttc
atataccagaatgaatttttaggctgcactgacaggcttgtaataactccacttacagac
agatgttacatcacgctggctcaagctctgggaatgagcatggggggagcccctgctgga
cctgcaggcacaggcaaaacagaaaccactaaagacatgggacgatgcctcgggaaatac
gtcgtggttttcaattgttcagaccagatggatttccgaggacttggacggatttttaag
ggactggcacagtctggatcctggggttgttttgatgaatttaaccgtattgatctacca
gttctctcggttgcagcccagcaaatttccattattctgacatgtaaaaaggagcacaaa
aagtcttttatctttactgatggagataatgtgactatgaaccctgaatttgggcttttc
ttaaccatgaatcctggctatgccggacggcaggaactccctgaaaacttgaagattaat
ttccgctcagtggccatgatggtgcctgaccgtcagattatcataagggtgaagttggct
agttgtggcttcattgacaacgttgttttggccaggaagtttttcacgctctacaaactg
tgtgaggagcagctttctaagcaggttcattatgactttggcctgcgtaacattctgtca
gttcttcggaccttgggagcagcaaaaagagccaatccaatggatacggagtccacgatt
gtcatgcgtgtactacgggacatgaatctttctaaactgattgatgaggatgaacccttg
tttttgagtttgattgaagatctctttccaaatattcttctggacaaggcaggttaccct
gaactggaagcagcaattagtagacaggttgaagaagctggtttaatcaaccatcctcct
tggaaactgaaggtcatccagctattcgaaacgcagagagtgcgacatgggatgatgact
ctggggcccagtggggctgggaagaccacctgcatccacaccttgatgagagccatgaca
gattgtggaaaaccacatcgggaaatgaggatgaatcccaaagcgattactgccccacag
atgtttggtcggctggacgttgccacaaatgactggactgatgggatattttctacgctt
tggaggaaaacattaagagcaaagaaaggggaacatatctggataattcttgatggtcca
gtagatgccatctggattgaaaatctgaattctgttttggatgataacaaaactctaacc
cttgccaatggtgatcggattcccatggctccaaactgcaagatcattttcgagcctcat
aacattgacaatgcttctcctgccaccgtctcaagaaatggaatggttttcatgagctct
tctatccttgattggagtcctattcttgagggttttcttaagaaacgctcacctcaagaa
gcagaaattcttcgtcagctgtacaccgagtctttcccagacttgtatcgcttctgtatc
cagaacttagaatacaagatggaggtgctggaggcctttgtcatcacacagagcattaac
atgcttcaaggcctgattcctctgaaggagcaaggcggggaggtgagccaggctcacctg
gggcggctgttcgtgttcgcgctgctgtggagcgcgggggcggcgctggagctggacgga
cggcgccgcctggagctctggctgcgctctcggcccacagggacgctggagctgccgccg
ccagcggggcccggggacaccgccttcgactactatgtggcgcccgatggtacatggacg
cactggaacacgcgtacccaggaatacctgtatccgtctgataccaccccagagtatggt
tctattctggtgccaaatgttgacaatgtgaggactgactttctaattcaaaccattgct
aaacagggcaaggctgtgctattaattggtgaacaaggaacagccaaaacagtaataatt
aaaggatttatgtcaaaatatgatcctgaatgtcacatgatcaagagtctgaatttttct
tctgcaaccaccccactgatgttccagaggacgatagagagctatgtggataaacgaatg
ggtacaacatatggccctcctgcgggaaagaagatgactgtttttattgatgatgtgaat
atgccaataatcaatgagtggggagatcaggttacgaatgagatagtgcgacagctgatg
gaacaaaatggattctataatctagagaagcctggggagttcaccagcatcgtggacatc
cagtttttggcagccatgatccatcctggtggtggacgcaatgacataccccaaagactc
aagaggcagttctctatatttaattgcacgttgccctctgaagcttctgtggacaagatc
tttggtgtgattggggtaggccactactgtactcagaggggtttctcagaagaagtgaga
gattctgtgacaaaattggtgcctctgacacgccgactatggcagatgaccaagattaaa
atgcttcctacccctgcaaaattccattatgtgtttaacctacgagatctttctcgggtc
tggcagggaatgctgaacactacttcagaggtcatcaaggaaccaaatgatctgttaaag
ctgtggaagcatgagtgtaaacgtgttatagctgaccgtttcacagtgtccagtgatgtg
acctggtttgataaggctttagtaagtttggtagaggaggagtttggtgaagagaaaaaa
ctcttggtggattgtggaattgacacatattttgtggatttcttgagagatgcacctgaa
gctgcaggtgaaacatctgaagaggctgatgctgaaacacctaaaatttatgagccaatt
gaatcttttagtcacctaaaagagcgtctgaatatgttcctgcagctctataatgagagc
atccgtggcgccggcatggacatggtgttctttgcagatgccatggttcacttagtcaag
atctctcgtgtcattcgtactcctcagggaaatgccctcctggtcggggtgggcggatca
ggaaagcagagcctgacgaggttggcttcattcattgctggctacgtttccttccagatc
actctgacgagatcctacaacacatcaaatctgatggaagatctgaaggttttgtatcga
acagctggtcagcaaggcaaaggaatcacttttattttcacagacaatgagattaaagat
gagtcatttttggaatatatgaacaatgttttatcatcaggtgaggtctctaacctattt
gctcgagatgaaattgatgaaattaatagcgacctggcatcagtcatgaaaaaagaattc
cccaggtgccttcctaccaatgagaacctgcacgactacttcatgagtcgggtccgacag
aaccttcatattgtgctctgcttctcgccagtgggggagaaatttcgaaacagagctttg
aagttccctgccctaatttcaggatgcacaattgactggttcagccgatggcccaaagat
gctttagttgctgtgtctgaacacttcctcacttcctatgatattgactgcagtttggaa
atcaagaaggaggtggtccaatgcatgggctccttccaggatggggtggctgagaagtgt
gttgattattttcagagattccgacgttctacccacgtgacgcccaaatcatacctctcc
tttattcagggctataagttcatatatggagaaaagcatgtggaggtgcggaccctggcc
aacagaatgaatactggattggaaaagctcaaagaagcttcagagtctgttgcagccttg
agtaaagaactggaagcgaaagaaaaggagctacaagtggccaacgataaagccgacatg
gtcttaaaagaagtgacaatgaaagcacaggctgctgaaaaggtcaaggctgaggtacag
aaggtgaaggacagggcccaggccattgtggacagcatctctaaagacaaagccattgct
gaagaaaaactggaagcagcaaaaccagctttagaagaggcagaagctgcattgcagacc
atcaggccttcggacatcgccactgttcgcacgttgggccgcccccctcacctcatcatg
cggatcatggattgcgtactgctgctgtttcaaaggaaagtcagtgctgtgaaaattgac
ctggaaaaaagctgtaccatgccctcctggcaggaatccttaaaattgatgactgcaggg
aactttttacagaacttacagcaattcccaaaagacacaatcaatgaagaggtgatagaa
tttttgagtccttactttgaaatgcctgactataacatcgaaactgctaaacgcgtatgt
ggaaatgtagctggtctttgttcctggacgaaagctatggcttccttcttttctataaac
aaagaagtactgcctctgaaggccaacttggtggtgcaagagaatcgccatctcctggcc
atgcaggatctgcagaaagcccaggccgagttggatgacaagcaggcggaacttgacgtg
gtgcaggctgagtatgaacaggccatgactgaaaagcagaccttgcttgaagatgcagag
cgatgcagacacaagatgcagacagcttccacgctcatcagtggcttggcaggtgaaaaa
gaaagatggacagagcaaagccaagagtttgctgcacaaactaaaagacttgtaggggat
gtactgttggctacagcttttctatcttattctggtccatttaaccaagagtttcgtgat
cttctgttaaatgactggcggaaggaaatgaaagcccggaaaattccatttggaaagaac
ctaaatctcagtgagatgttgattgatgctcctactattagtgaatggaacctccaaggt
ctgccaaatgatgacttgtccattcaaaatggaattattgtcacgaaggcatctcgttac
cctttgttaattgatccacagactcaaggcaagatctggattaaaaataaagaaagccga
aatgaactccagatcacgtctttaaatcacaagtacttcagaaaccacctggaagacagc
ctttctcttggaaggcctttgcttattgaagatgttggagaggaactagatccagcacta
gataatgttttggaaagaaacttcattaaaactgggtctacctttaaggtgaaagttggt
gacaaggaagtagatgtgttggatggctttagactctacattaccaccaaattgcctaac
ccagcctacacccctgagataagtgcccgtacctccatcattgacttcactgtcaccatg
aaaggtctagaagatcagttactggggagggtcattctcacagagaagcaggaattggag
aaagaaagaactcatctgatggaagatgtaactgcaaacaaaagaaggatgaaggaacta
gaagataacttgctttaccgcctgacaagtacccaggggtccctggtagaagatgaaagt
ctcattgtcgtgctgagtaacacaaaaaggacagccgaggaggtgacacagaagctagaa
atttctgctgagacagaagttcaaattaactcagcccgggaggaatacagacctgtggct
acgcggggcagcatcctctacttcctcattactgagatgcgcttggttaatgagatgtat
cagacttcgcttcgccagtttctgggcttatttgacctttccttagccaggtctgtcaag
agcccgattacaagcaagaggattgctaatatcatcgagcacatgacctacgaggtttat
aagtatgctgcccgagggctgtacgaggagcacaaattcctgttcaccttgttgcttacc
ctaaagattgacatccagaggaaccgagtcaagcatgaagagtttctcactcttattaaa
ggaggtgcctcattagaccttaaagcttgtcctccaaaaccatcaaaatggatcctggac
ataacatggctgaatttggtggaacttagcaaactcagacagttttcagatgtccttgac
cagatatcgagaaatgagaaaatgtggaaaatttggtttgataaggaaaacccggaggag
gaacctcttccaaatgcctatgataaatctcttgactgcttcagacgtcttctccttatt
agatcctggtgtcctgacagaaccatcgcccaggcccgcaagtacatcgtggactccatg
ggagaaaaatatgccgaaggtgttattttagacttggagaagacgtgggaggaatctgat
ccacggacgccactcatctgtctcctgtctatgggctcagaccccacagattccatcatt
gccttggggaagagattaaaaatagaaacccgttatgtgtccatgggccagggccaggaa
gtccatgctcggaagctcttgcagcagaccatggcgaacggaggatgggcacttctgcag
aactgccatctgggacttgatttcatggatgagctgatggacataatcatagaaactgag
cttgtacatgatgcgttccgcctctggatgaccaccgaggctcataagcagtttcccatt
acactccttcagatgtccattaaatttgccaacgatcctccacaaggactccgggcagga
ctgaaaagaacatatagtggtgtcagccaagacctgctggacgtgagctctgggtcccag
tggaagcccatgctgtacgcagtggctttcctgcactccactgtccaggagaggcgcaag
ttcggtgccctggggtggaatatcccctacgaatttaaccaagcggactttaatgccact
gtgcagttcatccaaaaccacttggatgacatggatgtcaaaaagggtgtctcctggacc
accatccgctacatgataggagagattcaatatggaggcagagtcactgacgactatgat
aagagattgttgaacacatttgctaaggtttggttcagtgaaaatatgtttggaccagat
ttcagtttttaccaaggatacaatattccaaaatgcagcacagtggataactatcttcag
tatatccagagtttgcctgcctatgacagccctgaggtgtttgggctgcaccccaatgct
gacatcacctaccagagcaagctggccaaggacgtgctggacaccatcctaggcatccaa
cccaaggacacctctggtggaggggatgagacccgggaggcggtggtggcccggctggct
gatgatatgctggagaagctgcccccagactatgtcccctttgaagtaaaagagaggctg
cagaagatggggccattccagcctatgaacattttcctcaggcaggaaatagacagaatg
caaagggtactcagccttgtccgcagcaccctcactgagctgaaacttgctattgatggc
accatcatcatgagcgaaaatctgcgagatgcattggattgcatgtttgatgctagaatc
cctgcttggtggaaaaaagcttcttggatttctagtacactgggtttctggtttactgaa
cttatagaaagaaacagccagtttacctcgtgggttttcaatggccgacctcactgcttt
tggatgacgggtttttttaacccccagggatttttaactgcaatgcgacaggaaataact
cgggccaacaaaggctgggctctggacaatatggtgctttgcaatgaagtcaccaaatgg
atgaaggacgacatttctgcccctcccacagagggtgtctatgtctatggcttatatctt
gaaggtgctggctgggacaagaggaacatgaaactcattgaatcaaagccaaaagtgctc
tttgagttgatgcctgtcataaggatttatgcagaaaacaatactttacgagatcctcgg
ttttactcctgtcccatctataagaagccagttcgaacggacttgaactacattgccgct
gtggatctcaggacagcccagacccctgaacactgggtgctccgtggggttgcccttctg
tgtgatgtcaagtaa

KEGG   Homo sapiens (human): 1768Help
Entry
1768              CDS       T01001                                 

Gene name
DNAH6, DNHL1, Dnahc6, HL-2, HL2
Definition
(RefSeq) dynein axonemal heavy chain 6
  KO
K10408  dynein heavy chain, axonemal
Organism
hsa  Homo sapiens (human)
Pathway
hsa05016  Huntington disease
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09164 Neurodegenerative disease
   05016 Huntington disease
    1768 (DNAH6)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    1768 (DNAH6)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    Dyneins
     1768 (DNAH6)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: AAA_6 DHC_N2 AAA_8 Dynein_C AAA_9 AAA_7 AAA_lid_11 MT Dynein_heavy Dynein_AAA_lid AAA_5 AAA_lid_1 AAA AAA_18 AAA_22 TsaE AAA_16 T2SSE Sigma54_activat NB-ARC Caudo_TAP SLS
Motif
Other DBs
NCBI-GeneID: 1768
NCBI-ProteinID: NP_001361
OMIM: 603336
HGNC: 2951
Ensembl: ENSG00000115423
Vega: OTTHUMG00000128957
Pharos: Q9C0G6(Tbio)
UniProt: Q9C0G6
Position
2p11.2
AA seq 4158 aa AA seqDB search
MTFRATDSEFDLTNIEEYAENSALSRLNNIKAKQRVSYVTSTENESDTQILTFRHITKAQ
EKTRKRQQPIKLEPLPVLKVYQDHKQPEYIHEQNRFQLMTAGIIKRPVSIAKKSFATSST
QFLEHQDAVKKMQIHRPYVEVFSPSPPKLPHTGIGKRGLFGTRSSAYPKYTFHDREEVVK
ANIRDPLQIIKIIRENEHLGFLYMIPAVPRSSIEYDTYNLKVVSYENINKNDYYTISQRA
VTHIYNEDIEFIEIDRWEQEYLYHRELTKIPIFSLFRKWKAFSVWRKNVRSKKITGCQKS
LQKNLFIVNPHLRPALLKINELCYHLSFMGLCYIEKCHTYTLQEFKAAQVIRLAEVTERL
GEFRNEAKYVVRRACRFALRAAGFVPDDCAFGPFEDYHKVQSSGSFINTPHELPTYGDSE
KMTYTEQASKRHYCMRLTCFIRLNDYLIENTMHILTVNAVNSLLNHLTDKLKRTPSADVI
QKWITEEKPEVPDKKGTLMVEKQEEDESLIPMFLTELMLTVQSLLFEPSLEDFLDGILGA
VNHCQNTVLSVPNLVPDSYFDAFTSPYINNKLEGKTCGTGPSLAAVFEDDKNFHTIISQI
KETIQAAFESARIYAATFEKFQIFFKENESLDLQALKLQEPDINFFSEQLEKYHKQHKDA
VALRPTRNVGLLLIDTRLLREKLIPSPLRCLEVLNFMLPRQSKKKVDAIIFEAQDAEYKL
EFVPTTTTEYVHSLLFLDEIQERIESLEDEGNIVTQMYKLMEQYQVPTPPEDFAVFATMK
PSIVAVRNAIDKSVGDRESSIKQFCVHLGSDLEELNNEVNEVKLQAQDPQILDISADQDK
IRLILNNLQSVLADLQKRAFQYKSYQKNFKVEVSKFEALEEVSAELKLKQLLWDSFSEWD
KLQQEWLKSKFDCLDPEVLNGQVSKYAKFVTQLEKGLPPNSVVPQLKYKVEKMKEKLPVI
IDLRNPTLKARHWAAIEQTVDATLVDAEIPLTLERLSQLHVFDFGQEIQDISGQASGEAA
LEAILKKVEDSWKTTEFVILPHRDSKDVFILGGTDDIQVLLDDSTINVATLASSRYLGPL
KTRVDEWQKQLALFNQTLEEWLTCQRNWLYLESIFNAPDIQRQLPAEAKMFLQVDKSWKE
IMRKVNRLPNALRAATQPGLLETFQNNNALLDQIQKCLEAYLESKRVIFPRFYFLSNDEL
LEILAQTRNPQAVQPHLRKCFDSISKLEFALMPPAEGKIPGIDGEPEKVYTNDILAMLSP
EGERVSLGKGLKARGNVEEWLGKVEEAMFTSLRRLCKAAIADYQGKLRTDWVVAGHPSQV
ILTVSQIMWCRDLTECLETEHSNHIQALKNFEKVNFERLNALAAIVQGSLPKLHRNILTA
LITIDVHARDIVTELVQSKVETVESFDWQRQLRYYWDIDLDNCVARMALSQYTYGYEYLG
ACPRLVITPLTDRCYLCLMGALQLDLGGAPAGPAGTGKTETTKDLAKALAIQCVVFNCSD
GLDYKMMGRFFSGLAQSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKAAKLSRFMFEGR
EIKLVMTCAAFITMNPGYAGRTELPDNLKALFRPFAMMVPNYALIAEVILYSEGFESSKI
LARKMTQMYKLCSEQLSQQDHYDFGMRAVKSVLVMAGSLKRENPDLNEDVVLIRALQDSN
LPKFLTDDALLFSGIISDLFPGVQIPEHDYGILQSTIVDVMNRQNLQPEMCMVRKVIQFY
ETMLVRHGVMLVGPTGGGKTTVYRILAETLGNLQKLGIENSFYQAVKTYVLNPKSITMGE
LYGEVNNLTLEWKDGLMALSVRAAVNDTSEDHKWIISDGPVDALWIENMNTVLDDNKMLC
LANSERIKLTPQIHMLFEVQDLRVASPATVSRCGMVFVDPEELKWMPYVKTWMKGISKKL
TEETQEYILNLFQRYVDEGLHFINKKCSQAIPQVDISKVTTLCCLLESLILGKDGVNLAM
EQTKLNTILCQTFVFCYLWSLGGNLTENYYDSFDTFIRTQFDDNPDARLPNSGDLWSIHM
DFDTKRLDPWERIIPTFKYNRDVPFFEMLVPTTDTVRYGYLMEKLLAVKHSVLFTGITGV
GKSVIAKGLLNKIQESAGYVPVYLNFSAQTSSARTQEIIESKLERKRKNILGAPGNKRIV
IFVDDLNMPRLDRYGSQPPIELLRQYQDFGGFYDRNKLFWKEIQDVTIISACAPPGGGRN
PVTPRFIRHFSMLCLPMPSEHSLKQIFQAILNGFLSDFPPAVKQTASSIVEASVEIYNKM
SVDLLPTPAKSHYVFNLRDLSKCVQGILQCDPGTIREEIQIFRLFCHECQRVFHDRLINN
EDKHYFHVILTEMANKHFGIAIDLEYFLNKPIIFGDFIKFGADKADRIYDDMPDIEKTAN
VLQDYLDDYNLTNPKEVKLVFFQDAIEHVSRIARMIRQERGNALLVGVGGTGKQSLTRLA
AHICGYKCLQIELSRGYNYDSFHEDLRKLYKMAGVEDKNMVFLFTDTQIVVEEFLEDINN
ILNSGEVPNLFEKDELEQVLAATRPRAKEVGISEGNRDEVFQYFISKVRQKLHIVLCMSP
VGEAFRSRCRMFPSLVNCCTIDWFVQWPREALLSVSKTFFSQVDAGNEELKEKLPLMCVN
VHLSVSSMAERYYNELRRRYYTTPTSYLELINLYLSMLSEKRKQIISARDRVKNGLTKLL
ETNILVDKMKLDLSALEPVLLAKSEDVEALMEKLAVDQESADQVRNTVQEDEATAKVKAE
ETQAIADDAQRDLDEALPALDAANKALDSLDKADISEIRVFTKPPDLVMTVMEAISILLN
AKPDWPSAKQLLGDSNFLKRLLEYDKENIKPQILAKLQKYINNPDFVPEKVEKVSKACKS
MCMWVRAMDLYSRVVKVVEPKRQKLRAAQAELDITMATLREKQALLRQVEDQIQALQDEY
DKGVNEKESLAKTMALTKARLVRAGKLTAALEDEQVRWEESIQKFEEEISNITGNVFIAA
ACVAYYGAFTAQYRQSLIECWIQDCQSLEIPIDPSFSLINILGDPYEIRQWNTDGLPRDL
ISTENGILVTQGRRWPLMIDPQDQANRWIRNKESKSGLKIIKLTDSNFLRILENSIRLGL
PVLLEELKETLDPALEPILLKQIFISGGRLLIRLGDSDIDYDKNFRFYMTTKMPNPHYLP
EVCIKVTIINFTVTKSGLEDQLLSDVVRLEKPRLEEQRIKLIVRINTDKNQLKTIEEKIL
RMLFTSEGNILDNEELIDTLQDSKITSGAIKTRLEEAESTEQMINVAREKYRPVATQGSV
MYFVIASLSEIDPMYQYSLKYFKQLFNTTIETSVKTENLQQRLDVLLEQTLLTAYVNVSR
GLFEQHKLIYSFMLCVEMMRQQGTLSDAEWNFFLRGSAGLEKERPPKPEAPWLPTATWFA
CCDLEESFPVFHGLTQNILSHPISIRLGSFETYINPQKWEGYSKMKHEDKHMRQEKEAAH
QDPWSAGLSSFHKLILIKCCKEEKVVFALTDFVIENLGKQFIETPPVDLPTLYQDMSCNT
PLVFILSTGSDPMGAFQRFARESGYSERVQSISLGQGQGPIAEKMVKDAMKSGNWVFLQN
CHLAVSWMLAMEELIKTFTDPDSAIKDTFRLFLSSMPSNTFPVTVLQNSVKVTNEPPKGL
RANIRRAFTEMTPSFFEENILGKKWRQIIFGICFFHAIIQERKKFGPLGWNICYEFNDSD
RECALLNLKLYCKEGKIPWDALIYITGEITYGGRVTDSWDQRCLRTILKRFFSPETLEED
YKYSESGIYFAPMADSLQEFKDYIENLPLIDDPEIFGMHENANLVFQYKETSTLINTILE
VQPRSSTGGEGKSNDEIVQELVASVQTRVPEKLEMEGASESLFVKDLQGRLNSLTTVLGQ
EVDRFNNLLKLIHTSLETLNKAIAGFVVMSEEMEKVYNSFLNNQVPALWSNTAYPSLKPL
GSWVKDLILRTSFVDLWLKRGQPKSYWISGFFFPQGFLTGTLQNHARKYNLPIDELSFKY
SVIPTYRDQAAVIEAAKTVQFGQELPMDMELPSPEDGVLVHGMFMDASRWDDKEMVIEDA
LPGQMNPVLPVVHFEPQQNYKPSPTLYHCPLYKTGARAGTLSTTGHSTNFVVTVLLPSKR
SKDYWIAKGSALLCQLSE
NT seq 12477 nt NT seq  +upstreamnt  +downstreamnt
atgacttttcgggccacagatagtgaatttgacctgacaaatattgaagagtatgccgaa
aattctgcactttcaagactgaataatataaaagccaaacaaagagtgagttatgtgaca
tccacagaaaatgaatctgatacacaaatcctaacgtttaggcacattacaaaagctcag
gagaagacaagaaaacgacagcagcctataaaactagagcctttgccagtgctaaaagtc
taccaagatcataagcagccagaatacatacatgaacagaaccgatttcagttaatgact
gcaggaatcattaaacgtccagtaagcatagcaaaaaaaagttttgccacatcatctact
cagtttcttgagcatcaagatgctgtgaaaaaaatgcagattcatcggccctatgttgag
gtgttctctccctctcctcctaaactgccacatactggtattggaaaaagaggtctcttt
gggactagatcttcagcttaccctaagtacacttttcacgaccgagaagaagttgttaaa
gccaacattcgtgatcccttgcaaatcattaaaataatacgtgaaaatgaacatcttgga
tttctttatatgatccctgcagtgccaagatcatccattgaatatgatacatataatcta
aaagttgtaagttatgagaacatcaataaaaatgactactatactattagccaaagggca
gtaacacacatttataatgaagacattgaatttatcgaaattgatcgatgggaacaggaa
tatctgtatcacagagaactcactaagattcccatattttcactgttccggaaatggaag
gcttttagtgtatggaggaagaatgtccgctccaagaaaatcactggatgtcaaaaatct
ctacaaaaaaatttgttcattgttaatcctcatttgcgaccagctcttcttaaaataaat
gaattgtgttatcatttgagttttatgggactttgttatattgaaaagtgtcacacctac
accctgcaggaatttaaggccgcacaagtcatacggctagcagaggtgacagaacgccta
ggagaatttcgaaatgaggcaaaatatgtagtcaggagggcttgtcgatttgctttgcgt
gctgcaggatttgttcctgatgactgtgcatttggaccttttgaggattatcataaagtg
cagagcagtggaagtttcattaatacaccacatgagttgcccacttatggagactctgag
aaaatgacatatacagaacaggccagcaaaaggcattattgcatgaggctgacgtgcttt
attcgtctaaacgactatctaattgagaacacaatgcacatcttaacggtaaatgctgtt
aattcgcttttgaaccatctcactgacaagctaaaacgaacaccttcagcagatgtcatt
cagaaatggattactgaagagaagcctgaagtccctgataaaaaggggacccttatggtg
gaaaagcaagaagaagatgaatctctcatccccatgtttctcacagaactaatgttgaca
gtccagtcactgctctttgagccttctctggaagactttctggatggtattttgggtgca
gttaatcactgtcaaaacactgtgttatcagttcctaatctcgtgcctgattcgtatttt
gatgctttcaccagcccttatattaacaacaaacttgaaggaaaaacctgtggaactggg
ccaagtttagcagcagtatttgaggatgataagaattttcacacaattatttctcaaata
aaggaaaccattcaggccgcatttgaatcagcccgcatctatgcagctacctttgaaaag
ttccagatattcttcaaggaaaatgaaagtcttgatttacaagctcttaaacttcaggaa
cctgatattaacttttttagtgaacaactggaaaaatatcacaaacagcacaaggacgca
gtagcgctcagacccaccagaaatgtaggattgctgctcattgatactaggcttctaaga
gaaaaattaattccatcacctttgcgatgcttagaggtgctaaattttatgcttcctcgt
caaagcaagaaaaaagtggatgccattatctttgaggcacaagatgcagagtataaactt
gagtttgttccaactactaccacagaatatgttcatagcttattatttcttgatgaaatt
caggaacggattgaaagccttgaagatgaggggaatatagtgactcaaatgtacaagctt
atggaacaatatcaggtgcccacacctcctgaagactttgctgtttttgcaactatgaag
ccatccattgttgctgttcggaatgccattgataaatcagtgggtgatagagaatcaagc
attaagcaattttgtgtgcatttgggtagtgatcttgaagaattaaacaacgaagtgaat
gaagtaaaactgcaagcacaggatccacagattttagatatctctgctgaccaagacaaa
ataaggctcatattgaataatctgcaatctgttctggctgatcttcagaaacgtgcattt
cagtataagtcctatcagaagaattttaaggtagaagtgtccaagtttgaagctttggaa
gaagtcagtgctgaactgaagctcaaacaattgctctgggattctttctctgaatgggat
aaactccaacaagaatggttaaagtccaaatttgattgcctggatccagaagtcctaaac
ggtcaagtttctaaatatgctaaatttgtgactcaactggaaaaaggcttgccacccaac
agtgtagtgccccagctcaaatacaaggtggaaaaaatgaaagaaaagcttccagttatc
attgacttgaggaacccgactttgaaggcaagacattgggcagctattgaacaaacagtt
gatgccactctagtggatgctgaaattccattaaccttggagaggctctcccagttgcat
gtttttgactttggtcaagaaatccaggacatatctggacaggcttctggagaagctgcc
ttagaagcaattcttaaaaaggtggaggactcttggaaaacaactgaatttgtcattctg
cctcaccgtgactccaaagatgtgtttatactgggcggcacagatgacatacaggtcctt
cttgatgatagcaccatcaatgttgcaactcttgcctcatcacgttaccttggtccactg
aaaactcgagtggatgaatggcaaaaacaacttgctttatttaatcaaacactggaagag
tggctgacctgccagagaaactggctctacctagaaagtattttcaatgctccagacatt
cagaggcaattgcctgcagaggccaagatgttccttcaggtggataagtcatggaaagaa
atcatgagaaaggtgaatcggctgcctaatgctcttcgagccgctactcagccaggactt
ctggaaacttttcaaaacaataatgcattacttgaccaaattcagaagtgcctagaggca
tacttagaatcaaaaagagttatctttccaaggttttacttcttgtcaaatgatgaactt
ctggagattttggcccagacacgaaatccacaggccgtgcagccacacttaaggaaatgc
ttcgactccatttcaaagctcgaatttgctctcatgcctcctgccgaaggaaagattcct
ggtattgatggagaaccagaaaaggtttatactaatgatattttagcaatgctgtcacca
gagggagaaagggttagcttggggaaaggcctcaaggcccgaggcaatgtagaggaatgg
cttggtaaagtggaagaagccatgttcacatctctgcgtcgcctgtgcaaagctgccatc
gctgactatcaggggaaactgaggacagactgggtggttgctggccacccttctcaagtt
atcctgactgtttctcaaattatgtggtgccgtgatttgactgaatgtctggaaacagaa
cacagtaatcatatacaggccctgaagaattttgaaaaagtaaattttgagagattaaat
gccctagctgcaatagttcaaggcagtcttcctaaattacacagaaacatcctaactgca
ttgattactattgatgtgcatgcaagagatatagtcactgaacttgttcaatccaaggtg
gagacagttgaatcttttgactggcagagacaactgcgctattactgggatatagacctg
gataattgtgtggctagaatggcgctctctcagtacacttatggctatgaatatttgggt
gcatgcccaagattggttattactccactcacagatcgctgctatctttgcctcatggga
gctttgcagcttgaccttgggggtgcaccagctggtcctgctggcactgggaaaacagag
actaccaaagatctggcaaaagctcttgccatccagtgtgtggtctttaactgttcagat
ggtttggactacaagatgatggggcgcttcttcagtggcttggcacagtcaggggcctgg
tgctgctttgatgaatttaatcgaattgacatagaagttctgtccgtcatcgcgcagcaa
ctcattaccattaggaacgccaaagcggcaaagctctctagattcatgtttgaggggcgg
gaaataaagttggtgatgacttgtgcagccttcatcacaatgaatcctggctatgcaggg
agaactgaattgccagataatttgaaagccctgtttagaccatttgcgatgatggttcca
aattatgccttgattgcagaggtaattctatattctgaaggatttgaatccagtaaaata
ttagcaagaaaaatgactcagatgtataagctttgcagtgagcagctgtctcagcaggat
cactacgactttggcatgagagctgtgaagtctgtcctggtcatggctggatctttaaaa
agagaaaacccagacctaaatgaagatgtggtgttgataagagctttacaagactccaat
ttgccaaaatttctaacagatgatgctcttctgttcagtggaatcatatctgaccttttt
cctggagtccaaattccagaacatgattatggtattttacaatcaacaattgtggatgtc
atgaatagacaaaatcttcagcctgagatgtgtatggttagaaaggtgatacagttttat
gaaactatgctagtaaggcatggtgttatgttagtcgggccaacaggaggcggcaagacc
acagtttaccgaatactagcagaaactttagggaatttacaaaaacttgggatagaaaat
tccttttaccaagcagttaaaacatatgttctcaaccctaaatcaattaccatgggtgaa
ttatatggagaggttaataacttaaccttggaatggaaagatggtttgatggcactaagt
gtccgagcagctgtgaatgatacttcagaagaccataaatggatcatcagtgatgggcca
gtagatgctctttggattgaaaacatgaatacagtgctggatgataacaagatgctttgc
ctggctaacagtgagaggattaaactcacacctcaaattcacatgctttttgaggtgcaa
gatctgcgggttgcctcccctgcaacagtcagtcgatgtggaatggtgtttgtggatcct
gaagaactgaaatggatgccttatgttaaaacttggatgaagggtatttctaaaaaactg
actgaggaaacccaagaatatatattgaatcttttccaacgttatgttgatgaaggttta
cattttatcaataaaaagtgcagccaagcaattccacaagtggacatcagcaaagttact
acactctgttgcttattggagtccttgatacttgggaaagatggagttaacttggcaatg
gaacaaacaaaattgaacactatactatgtcagacttttgtattctgttatttgtggtct
ttgggtggaaacctaactgaaaactactatgattcttttgatacatttattagaacacaa
tttgatgataatcctgatgccaggcttcccaattctggtgatctgtggagcattcatatg
gactttgacaccaaacggctggatccctgggaacgaatcatacctactttcaaatacaac
cgagatgttccattttttgaaatgcttgtccccacaactgacacagtgcgctatgggtat
ctaatggaaaaactactggcagtcaagcattccgtgttgtttactggaataactggagtg
ggcaagtctgtgattgcaaaaggattgctaaataaaattcaagaatcagctggctatgtc
cctgtttatctaaatttttctgctcaaacttcatctgcaaggacacaagagatcattgag
tcaaaactggagagaaaaagaaaaaatattctaggagcaccgggaaacaaacgaattgtg
atttttgttgatgatttaaacatgcccagactggatcgctatggctctcagcctccgatt
gaattacttcggcagtatcaagattttgggggattttatgacagaaacaaactgttttgg
aaagaaatacaggatgtaacaatcatatcggcatgtgcacctccaggcggtggccgcaac
cctgtgactccccgcttcatcagacacttcagcatgctgtgcctcccaatgccctcagag
cacagtctgaaacagatttttcaggccatcttaaatggtttcctgagtgactttccacca
gctgtaaagcaaactgcatcaagcattgtagaagcctcagttgagatttataacaaaatg
agtgttgacctcctgccaacacccgccaagtcccattatgtctttaacttgagggactta
tccaaatgtgtgcaaggtatcctccaatgtgatccaggaacaataagagaagaaattcag
atatttagactcttttgccatgagtgccaaagggtcttccatgatcgcttgattaataat
gaagataagcactatttccatgttattctgacagaaatggccaacaaacattttggaatt
gcaattgacctggaatattttttgaataagcccatcatatttggagatttcattaagttt
ggagcagataaagctgatcggatttatgatgacatgcctgatatagagaaaactgcaaat
gttctacaggactatcttgatgattataatctcacaaatcccaaagaagtaaagttggtg
ttcttccaggatgctatagaacatgtttcaaggattgctcggatgatacgtcaagaaaga
ggcaatgccctgcttgttggagtaggaggcacaggaaagcagtcactcacgagacttgca
gctcatatatgcggttacaaatgtttgcagattgaactcagccggggatataattatgat
agttttcatgaagacctgaggaagttgtacaaaatggctggtgtagaagacaagaatatg
gttttccttttcactgacacccagattgtagtggaggagttcctagaagatataaataac
atcctgaactcaggtgaagtgcctaatttatttgaaaaggatgaactggagcaggtttta
gcggccaccagaccaagagcaaaagaagtaggaatttctgaggggaacagagacgaggtg
tttcaatactttatcagcaaagtgcgtcagaagctgcacattgttctctgcatgagccca
gttggggaggcctttcggtcccgatgcaggatgtttccatcccttgtgaattgctgcacc
attgactggtttgtgcagtggcccagagaagcacttctttctgtgtcaaagacatttttc
tcacaagtcgatgctggaaatgaagaactgaaagaaaagcttcccttgatgtgcgtgaac
gttcacttgagtgtctccagcatggcagagcgctattacaatgagctgcgcaggcggtac
tacacgacacccacctcctacctggagcttatcaatctttacctgtctatgctgtctgaa
aaaaggaagcagattatttcagcacgagatcgggtgaagaatggtctcaccaagctacta
gaaacaaacatactagtagataaaatgaaactagatctttcagctttagagcctgtactt
ttagcaaaatcagaagatgttgaagccctgatggaaaaattggcagtggatcaagaaagt
gccgatcaggtccgtaacactgtgcaggaggatgaagcaacagcaaaagtcaaagctgaa
gaaacccaagcaatagctgatgatgctcaaagagatcttgacgaggcactacctgcacta
gatgctgccaataaagcactggattccttagataaggcagatatatctgaaatcagagtt
tttacaaagcccccagatttggtcatgacagtaatggaagcaatctccattcttttgaat
gccaagcctgattggccatcagcaaagcaacttcttggtgactctaactttctaaaaagg
cttttagaatatgataaggagaacataaagcctcagatattggcaaagcttcaaaagtat
attaataatcctgattttgtgcctgaaaaagtggagaaagtgtccaaagcatgtaaatct
atgtgcatgtgggtaagagctatggatttgtactctcgagtggtcaaggtcgtcgaacca
aaaagacaaaagctccgcgccgcacaggctgaacttgacattaccatggctaccctgaga
gaaaagcaagcattactaagacaagtagaagatcaaatacaggccttacaagatgaatat
gacaaaggtgtaaatgaaaaagaaagcctggcaaagaccatggccctgacaaaagcacgt
ctagtacgtgctggaaagctgacagcagcattagaagatgagcaggttcgatgggaagaa
agcatacagaagtttgaggaagaaatatcaaatatcactgggaacgtgttcatagcagca
gcttgtgtggcctactatggggctttcacagcccagtacaggcagtcacttatagagtgt
tggatccaggactgtcagtctctggagatcccaatcgatccttccttcagtctcattaac
attcttggagatccctacgagatacggcagtggaacactgatgggctgccccgtgacttg
atatcaacagaaaatggcattttggttactcaaggcagaagatggcctttgatgattgat
ccccaagatcaggcaaaccgttggataaggaacaaggaaagcaaaagtggtttaaagatc
attaagcttacagatagtaatttcttacgaatactcgagaattcaatccgacttggttta
cctgtcttactggaagagcttaaggaaaccttggatccagctctagaacccattcttttg
aaacaaatttttatcagtggtggccgactactcatccgtcttggagactcagacattgat
tatgacaaaaactttaggttctatatgacaaccaaaatgccaaatccccactatctgcct
gaggtatgcattaaagttaccattatcaatttcactgtaacaaaatcaggcctggaggat
cagttgttaagtgatgtggtgcgacttgaaaaacccaggttggaagaacaaagaattaag
ctcatcgtgaggatcaacactgataaaaaccagttgaaaactatcgaagagaaaatcctg
agaatgctctttacctctgaaggaaatattctggacaatgaagaacttattgacacactc
caggattcaaagatcacttctggtgccattaaaaccaggctggaagaagcagagtccact
gagcagatgatcaatgtggctcgtgagaagtatcgtccagtggccactcaaggctctgta
atgtactttgtcattgcaagcctctcagaaatagatcctatgtaccagtactcattaaaa
tactttaaacagttgttcaataccaccattgaaacttctgtaaagacagaaaatctacaa
cagcgcctggacgtactactagaacaaactctcctaactgcttatgtcaatgtttcaaga
ggactttttgagcaacataaactcatctacagctttatgctttgtgttgagatgatgcgt
cagcaaggaaccctatctgatgctgaatggaatttctttctccgaggttctgcaggattg
gaaaaggaacgcccacctaagcctgaagctccctggctacctactgctacatggttcgca
tgctgtgacttggaagaatcatttccagtttttcacggacttacccaaaatatattgtca
catcctatttccatacgcttaggatcttttgagacttatattaacccacagaaatgggaa
ggctattctaaaatgaaacacgaagataaacacatgagacaggaaaaggaggcagcacac
caagatccatggagtgcaggattgagttctttccataagctaattcttattaaatgttgt
aaagaagaaaaggtggtttttgctcttacagactttgtgatagaaaatcttggaaaacag
tttatagagacaccacctgtggacctgcctaccctgtatcaagacatgtcatgcaacact
cccctggtattcatcctaagcacaggctcagatcccatgggtgcatttcagaggtttgcc
agggaaagtggatattcagaacgggtgcagtcaatttcactggggcaaggacaaggacct
attgctgaaaaaatggtcaaggatgcaatgaaatcaggaaactgggtatttttgcaaaat
tgccatcttgctgtttcttggatgttggcaatggaagagctcattaaaaccttcacagat
ccagatagtgctatcaaggacacttttcgactttttttaagctccatgcctagtaataca
tttcctgttacagttcttcaaaattctgtcaaggtgaccaatgagcctccaaaaggctta
cgtgcaaatatcagacgagcatttactgaaatgacaccttcgttttttgaagaaaatata
cttggaaaaaaatggagacaaataatatttggcatttgtttcttccatgcaattattcag
gagagaaagaagtttggcccccttggttggaatatctgctatgaatttaatgacagtgac
agggaatgtgctttactgaatctcaaactctattgtaaagaaggaaagattccctgggat
gcactaatttacattactggtgaaattacttatggtggtagagtcacagacagctgggac
caaagatgccttcgtactatcttgaaaagatttttttctcctgaaacattagaagaagat
tataaatactctgaatcaggcatctattttgcacccatggctgacagcctacaagagttt
aaggactacattgaaaatctgcctttgatcgatgacccagaaatttttggaatgcatgaa
aatgctaatctagtcttccagtacaaagagaccagcactttaatcaacaccatacttgag
gttcagccaaggtcatctactggtggagagggaaaaagcaatgacgaaattgttcaagaa
cttgttgcttctgtccagaccagagttccagaaaaactggaaatggagggtgcttctgag
agcctttttgtcaaggatcttcaaggacgtctgaactccttgaccaccgttcttggacag
gaagtggaccggtttaacaacctgctgaagttaattcatacttctctggaaacactcaac
aaagccatcgctggatttgtggtgatgtctgaagaaatggaaaaagtgtataacagtttc
ctcaacaaccaggttcccgctctgtggtccaacacagcctacccatccctgaagccacta
ggatcatgggtcaaagaccttatcctgaggacctcatttgtggatctgtggctcaaaaga
ggacagcctaagtcctactggatctctggtttcttctttcctcaaggatttctaacagga
actcttcaaaatcatgctcgaaaatacaatttgcctatagatgagctgagtttcaaatac
agcgtaattcccacctatcgggatcaagctgcagtgatagaagctgccaagacagtgcaa
tttggacaagaactgcccatggacatggagttgccctctcctgaggatggtgttcttgtt
catgggatgttcatggatgcttctcgatgggatgataaggagatggtgatagaagatgca
ttgcccggacagatgaatccagtgctgcctgtggtgcattttgaaccacaacaaaactat
aagccaagcccaacactttaccactgcccactttataaaacaggagcccgggcaggaaca
ctctcaaccacaggacattcaaccaattttgtggtaaccgtcctgttaccctccaagcgg
tccaaagactactggattgccaagggatcagctttgctctgccagctgagcgaatga

KEGG   Homo sapiens (human): 1769Help
Entry
1769              CDS       T01001                                 

Gene name
DNAH8, ATPase, hdhc9
Definition
(RefSeq) dynein axonemal heavy chain 8
  KO
K10408  dynein heavy chain, axonemal
Organism
hsa  Homo sapiens (human)
Pathway
hsa05016  Huntington disease
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09164 Neurodegenerative disease
   05016 Huntington disease
    1769 (DNAH8)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    1769 (DNAH8)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    Dyneins
     1769 (DNAH8)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: DHC_N1 AAA_6 DHC_N2 Dynein_C AAA_8 AAA_9 AAA_7 AAA_lid_11 MT Dynein_heavy AAA_5 Dynein_AAA_lid AAA_lid_1 AAA_16 AAA_33
Motif
Other DBs
NCBI-GeneID: 1769
NCBI-ProteinID: NP_001193856
OMIM: 603337
HGNC: 2952
Ensembl: ENSG00000124721
Vega: OTTHUMG00000016253
Pharos: Q96JB1(Tdark)
UniProt: Q96JB1 Q8IU65 A0A075B6F3
Position
6p21.2
AA seq 4707 aa AA seqDB search
MEKDAEDGAPSEGAEAPPSTEEAAPPRSEEEEAPRPPTVEAPAEDGFSPSAEDAVSSVVD
YRDLIPSEEGIVLPDDHEADLNRVRQRLAPRPVQSVISEVLSLPSSRRSSRYRRSMSGLP
NLQETLKERQARFREARESRRLKIDPSYKYIFEILAENLGLDIVTVEELILDCPSLEAFT
NFFAKDGCKTLKFLYQEGDVPGIECGRTIAGATKGAKMMKLYIDNAAPDKLKGLCIFFVR
CRNDVAINVKTIQEEALFTVLDASKGLLNGIRDMLANIFLPAVLATNNWGALNQSKQGES
EKHIFTETINRYLSFLDGARISIEGTVKLKTIDNVNFSKLHTFEEVTAAASNSETVHQLE
EVLMVWYKQIEQVLIESEQMRKEAGDSGPLTELEHWKRMSAKFNYIIEQIKGPSCKAVIN
VLNVAHSKLLKNWRDLDARITDTANESKDNVRYLYTLEKVCQPLYNHDLVSMAHGIQNLI
NAIRMIHGVSRYYNTSERMTSLFIKVTNQMVTACKAYITDGGLNHVWDQETPVVLKKIQD
CIFLFKEYQASFHKTRKLISESSGEKSFEVSEMYIFGKFEAFCKRLEKITEMITVVQTYS
TLSNSTIEGIDIMAIKFRNIYQGVKKKQYDILDPRRTEFDTDFLDFMTKINGLEVQIQAF
MNSSFGKILSSQQALQLLQRFQKLNIPCLGLEINHTIERILQYYVAELDATKKLYHSQKD
DPPLARNMPPIAGKILWVRQLYRRISEPINYFFKNSDILSSPDGKAVIRQYNKISYVLVE
FEVVYHTAWIREISQLHYALQATLFVRHPETGKLLVNFDPKILEVVRETKCMIKMKLDVP
EQAKRLLKLESKLKADKLYLQGLLQYYDELCQEVPSVFVNLMTPKMKKVESVLRQGLTVL
TWSSLTLESFFQEVELVLDMFNQLLKKISDLCEMHIDTVLKEIAKTVLISLPESGATKVE
DMLTLNETYTKEWADILNHKSKHVEEAVRELISIFEQIYEVKYTGKVGKQSEQRKHVVFG
SETGEGENNDYEANIVNEFDTHDKEDEFKKECKEVFAFFSHQLLDSLQKATRLSLDTMKR
RIFVASLYGRKQSEDIISFIKSEVHLAIPNVVMIPSLDDIQQAINRMIQLTLEVSRGVAH
WGQQQIRPIKSVIPSPTTTDVTHQNTGKLLKKEERSFEEAIPARKLKNFYPGVAEHKDIS
KLVLLLSSSVNSLRKAAHEALQDFQKYKTLWTEDRDVKVKEFLANNPSLTEIRSEILHYA
TFEQEIDELKPIIVVGALELHTEPMKLALSIEAKAWKMLLCRYLNEEYKKKMSYMIAFIN
EYLKKLSRPIRDLDDVRFAMEALSCIRDNEIQMDMTLGPIEEAYAILNRFEVEVTKEESE
AVDTLRYSFNKLQSKAVSVQEDLVQVQPKFKSNLLESVEVFREDVINFAEAYELEGPMVP
NIPPQEASNRLQIFQASFDDLWRKFVTYSSGEQLFGLPVTDYEVLHKTRKELNLLQKLYG
LYDTVMSSISGYYEILWGDVDIEKINAELLEFQNRCRKLPKGLKDWQAFLDLKKRIDDFS
ESCPLLEMMTNKAMKQRHWDRISELTGTPFDVESDSFCLRNIMEAPLLKHKDDIEDICIS
AIKEKDIEAKLTQVIENWTNQNLSFAAFKGKGELLLKGTESGEIITLMEDSLMVLGSLLS
NRYNAPFKKNIQNWVYKLSTSSDIIEEWLVVQNLWVYLEAVFVGGDIAKQLPQEAKRFQN
IDKSWIKIMQRAHENPNVINCCVGDETMGQLLPHLHEQLEVCQKSLTGYLEKKRLLFPRF
FFVSDPVLLEILGQASDSHTIQPHLPAVSDNINEVTFHAKDYDRIMAVISREGEKIVLDN
SVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLSHFPAQVGLLGIQML
WTHDSEEALRNAKDDRKIMQVTNQKFLDILNTLISQTTHDLSKFDRVKFETLITIHVHQR
DIFDDLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDVDFIYQNEFLGCTDRLVITP
LTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDFRGLGR
IFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQFIFSDGDCVDLNPEF
GIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQIIMRVKLASCGFLENVILAQKFYVL
YKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDSELSIVMRGLRDMNLSKLVDED
EPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQIEGLINHPPWNLKLVQLYETSLVRHG
LMTLGPSGSGKTTVITILMKAQTECGRPHREMRMNPKAITAPQMFGRLDTATNDWTDGIF
STLWRKTLKAKKGENIFLILDGPVDAIWIENLNSVLDDNKTLTLANGDRIPMAPSCKLLF
EVHNIENASPATVSRMGMVYISSSALSWRPILQAWLKKRTAQEAAVFLTLYEKVFEDTYT
YMKLNLNPKMQLLECNYIVQSLNLLEGLIPSKEEGGVSCVEHLHKLFVFGLMWSLGALLE
LESREKLEAFLRQHESKLDLPEIPKGSNQTMYEFYVTDYGDWEHWNKKLQPYYYPTDSIP
EYSSILVPNVDNIRTNFLIDTIAKQHKAVLLTGEQGTAKTVMVKAYLKKYDPEVQLSKSL
NFSSATEPMMFQRTIESYVDKRIGSTYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVR
QMMEMEGMYSLDKPGDFTTIVDVQLIAAMIHPGGGRNDIPQRLKRQFTVFNCTLPSNASI
DKIFGIIGCGYFDPCRSFKPQICEMIVNLVSVGRVLWQWTKVKMLPTPSKFHYIFNLRDL
SRIWQGMLTIKAEECASIPTLLSLFKHECSRVIADRFITPEDEQWFNAHLTRAVEENIGS
DAASCILPEPYFVDFLREMPEPTGDEPEDSVFEVPKIYELMPSFDFLAEKLQFYQRQFNE
IIRGTSLDLVFFKDAMTHLIKISRIIRTSCGNALLVGVGGSGKQSLSRLASFIAGYQIFQ
ITLTRSYNVTNLTDDLKALYKVAGADGKGITFIFTDSEIKDEAFLEYLNNLLSSGEISNL
FARDEMDEITQGLISVMKRELPRHPPTFDNLYEYFISRSRKNLHVVLCFSPVGEKFRARS
LKFPGLISGCTMDWFSRWPREALIAVASYFLSDYNIVCSSEIKRQVVETMGLFHDMVSES
CESYFQRYRRRAHVTPKSYLSFINGYKNIYAEKVKFINEQAERMNIGLDKLMEASESVAK
LSQDLAVKEKELAVASIKADEVLAEVTVSAQASAKIKNEVQEVKDKAQKIVDEIDSEKVK
AESKLEAAKPALEEAEAALNTIKPNDIATVRKLAKPPHLIMRIMDCVLLLFQKKIDPVTM
DPEKSCCKPSWGESLKLMSATGFLWSLQQFPKDTINEETVELLQPYFNMDDYTFESAKKV
CGNVAGLLSWTLAMAIFYGINREVLPLKANLAKQEGRLAVANAELGKAQALLDEKQAELD
KVQAKFDAAMNEKMDLLNDADTCRKKMQAASTLIDGLSGEKIRWTQQSKEFKAQINRLVG
DILLCTGFLSYLGPFNQIFRNYLLKDQWEMELRARKIPFTENLNLISMLVDPPTIGEWGL
QGLPGDDLSIQNGIIVTKATRYPLLIDPQTQGKTWIKSKEKENDLQVTSLNHKYFRTHLE
DSLSLGRPLLIEDIHEELDPALDNVLEKNFIKSGTTFKVKVGDKECDIMDTFKLYITTKL
PNPAFTPEINAKTSVIDFTVTMKGLENQLLRRVILTEKQELEAERVKLLEDVTFNKRKMK
ELEDNLLYKLSATKGSLVDDESLIGVLRTTKQTAAEVSEKLHVAAETEIKINAAQEEFRP
AATRGSILYFLITEMSMVNIMYQTSLAQFLKLFDQSMARSEKSPLPQKRITNIIEYLTYE
VFTYSVRGLYENHKFLFVLLMTLKIDLQRGTVKHREFQALIKGGAALDLKACPPKPYRWI
LDMTWLNLVELSKLPQFAEIMNQISRNEKGWKSWFDKDAPEEEIIPDGYNDSLDTCHKLL
LIRSWCPDRTVFQARKYIADSLEEKYTEPVILNLEKTWEESDTRTPLICFLSMGSDPTNQ
IDALAKKLKLECRTISMGQGQEVHARKLIQMSMQQGGWVLLQNCHLGLEFMEELLETLIT
TEASDDSFRVWITTEPHDRFPITLLQTSLKFTNEPPQGVRAGLKRTFAGINQDLLDISNL
PMWKPMLYTVAFLHSTVQERRKFGPLGWNIPYEFNSADFSASVQFIQNHLDECDIKKGVS
WNTVRYMIGEVQYGGRVTDDFDKRLLNCFARVWFSEKMFEPSFCFYTGYKIPLCKTLDQY
FEYIQSLPSLDNPEVFGLHPNADITYQSNTASAVLETITNIQPKESGGGVGETREAIVYR
LSEDMLSKLPPDYIPHEVKSRLIKMGHLNSMNIFLRQEIDRMQRVISILRSSLSDLKLAI
EGTIIMSENLRDALDNMYDARIPQLWKRVSWDSSTLGFWFTELLERNAQFSTWIFEGRPN
VFWMTGFFNPQGFLTAMRQEVTRAHKGWALDTVTIHNEVLRQTKEEITSPPGEGVYIYGL
YMDGAAWDRRNGKLMESTPKVLFTQLPVLHIFAINSTAPKDPKLYVCPIYKKPRRTDLTF
ITVVYLRTVLSPDHWILRGVALLCDIK
NT seq 14124 nt NT seq  +upstreamnt  +downstreamnt
atggagaaggatgctgaagatggcgccccttctgagggagcagaggctcctccctctacg
gaagaggctgcccctccccgttcagaagaggaagaggccccgcgccctccgacagtggag
gccccggcagaagatggtttctctccttccgcagaagatgctgtttcttctgtggtggat
tatcgggatctcattccttctgaagaagggatagttcttccagatgatcatgaagcggat
ctgaatagagttcgacagaggcttgcaccgcgaccggttcagtcagtgatttcggaagtg
ctgtccttgccgtcttcccggaggtcctccagataccgccggagtatgagtggccttccc
aatctacaggaaacattaaaagagagacaggcaagatttagagaggcaagggaaagccga
agactgaaaattgacccttcatacaaatatatatttgaaattctagcagaaaatcttggc
ctggacatagtaactgttgaagaattaattttggattgcccatctctggaagcatttact
aatttttttgcgaaagatggttgtaagacactgaaatttttgtaccaagaaggagatgta
cctggtattgaatgtggtcgaactattgctggagcaactaaaggggcaaaaatgatgaaa
ttgtatatagacaatgcagccccggataaactaaaaggactgtgcatattttttgttcgt
tgccgtaatgatgttgctataaatgttaaaactattcaagaggaagcgctctttactgtt
ctggatgcgtcgaaaggactcttaaatggaattagggatatgttggcaaatatatttcta
ccagctgttcttgcaacaaacaactggggtgctttaaaccagtccaagcagggagaatct
gaaaaacatattttcactgaaaccatcaacagatatctttcatttttagatggtgctaga
ataagtattgagggaacagtgaagttaaagacaatagacaatgttaatttttccaaactg
cacacctttgaagaagtaactgctgcagccagcaactcagaaactgttcatcagctggag
gaagtgctgatggtatggtacaaacagatcgaacaggtacttattgagagtgagcagatg
agaaaagaagctggtgattcaggtccactcactgaattggaacactggaaacgcatgtca
gccaagttcaactatatcattgagcagattaaagggccaagttgtaaggctgtcataaat
gtgctaaatgttgcacactccaaactgctaaagaattggcgtgatttggatgcaagaatc
actgatacagcaaatgaatccaaagataatgtcagatatttgtatactttggaaaaagtg
tgtcaacctctctataaccatgacctagtttccatggcacatggaatacaaaatttgatt
aatgccatcagaatgattcacggtgtgtcaaggtattataatacctcagagagaatgacc
tcattgtttatcaaggtaacaaatcaaatggtaacagcatgtaaagcatatattactgat
ggaggattaaaccatgtatgggatcaggaaacgccagttgtactaaagaaaattcaggac
tgcatttttctattcaaggaatatcaggcatcttttcataaaacaaggaaactgatttca
gaatcctcaggggaaaaatcttttgaggtttcagaaatgtatatatttggaaaatttgaa
gctttttgcaaaagactggagaagattacagaaatgataactgttgtgcaaacatattca
accttgagtaattctaccatagaaggaatagatattatggcaataaaattcagaaatata
taccaaggggttaagaaaaagcaatatgacattctggatccaagaaggacagaatttgac
acagatttcttagatttcatgacaaaaatcaatggtttagaggtacaaatacaggcattt
atgaacagtagttttgggaaaatcttatcttctcagcaggctcttcagctacttcaaagg
tttcagaagctgaacattccctgtctgggattagaaataaaccacacaatagagcgtatt
cttcagtactatgtggctgaacttgatgctactaagaagctttatcattctcagaaagat
gacccccctcttgctcgcaacatgccccctatagcaggaaaaatactctgggtgaggcag
ctctatcgccggataagtgagcccatcaattatttctttaaaaactcagacattttatca
agtccggacggtaaagctgtcatccgtcagtataacaagatctcctatgtgctggtggaa
ttcgaggtggtctatcacacagcctggatcagagagatttcacagttgcattacgcttta
caagccacgctttttgtgcgacatccagaaacagggaagttgctggttaatttcgatccc
aaaattttggaagttgttcgggaaactaagtgtatgataaaaatgaagttggatgtacca
gaacaggcaaagagattgctaaaattggaaagtaaattgaaagcagacaaactgtatttg
cagggtcttctgcaatattatgatgagttatgtcaggaagtgccttctgtgtttgtcaat
ctgatgaccccaaaaatgaaaaaggtggaatctgtgttgaggcaaggactcacagtgtta
acatggtcgtctttaacactggaaagcttctttcaagaagtcgaattagttttggatatg
ttcaatcaacttttaaagaagatcagtgacttgtgtgaaatgcatattgatacagttctg
aaggagatagccaaaactgtgttgatttctctgcctgaaagtggtgctaccaaagtagaa
gatatgttgaccctcaatgagacatacacaaaagaatgggctgacattctaaaccacaaa
agtaagcatgtggaagaagctgtcagagaacttatatcaatatttgagcagatttatgaa
gtgaaatacactgggaaagtaggaaaacagtcagaacagcggaaacacgttgtttttgga
agtgaaacaggagagggtgaaaacaatgactatgaagctaatattgtgaatgagtttgat
actcatgataaagaagatgaatttaaaaaggagtgtaaagaggtctttgcttttttctct
catcaattactagacagtcttcaaaaagctacacggttatctctggacacaatgaaaaga
agaatatttgttgcaagcctttatgggcgaaagcagtcagaagatattatttcctttata
aaaagtgaagtacatcttgcaattcctaatgtggtgatgattcctagtttggatgacatt
caacaagccattaaccgtatgatccagttaaccctggaggtcagcagaggagtggctcac
tgggggcaacagcaaatccgtcccatcaagtctgtcattcccagccccaccactactgac
gtgacccatcaaaacacaggaaaactgctgaagaaggaagaaagatcttttgaagaagct
attcctgcgaggaagctgaagaatttttacccgggggtagcggagcacaaggatatttct
aagttggtcctgctcctttcttcctctgtaaattccctaagaaaggcagctcatgaggcc
ctgcaggactttcagaagtacaagactctctggacagaggaccgcgatgtgaaagtgaag
gaatttttggctaacaacccctctctgactgaaatcagatcagaaattctacactatgct
acttttgaacaggagattgatgagttgaagcctattattgttgtaggagcacttgaatta
catacagagccgatgaaattggccttatccatcgaggccaaggcatggaagatgttactc
tgtcgatatctgaatgaagaatacaaaaagaaaatgtcatacatgatagcatttattaat
gaatacttgaaaaagttatctagacctattcgtgatttagatgatgtcagatttgcaatg
gaagccttgtcttgcatacgtgataatgaaattcaaatggacatgactttgggaccaatt
gaagaagcctatgctattttaaacagatttgaagttgaagtaaccaaagaagaatcagaa
gcagttgataccttaagatattctttcaacaaattgcagagcaaagctgtttcagtacaa
gaggacctagttcaagtgcagccaaagtttaaaagcaatctacttgagtctgtggaagtt
tttcgtgaggacgtgataaactttgcagaagcatatgaattggaaggacctatggttcca
aatataccaccccaagaagctagcaacaggctacagatatttcaggccagtttcgatgat
ctgtggaggaaatttgttacgtattcatctggtgaacaactttttggattgcctgtgact
gattatgaggttttacacaaaaccagaaaagaactcaacttgctgcagaagctgtatgga
ttgtatgacaccgtaatgagcagtattagtggttattatgaaatactttggggagatgta
gatattgaaaaaattaatgcagaactgctggaatttcaaaacagatgtcgtaaacttcca
aaaggacttaaagattggcaagcttttttggatctcaaaaagagaattgatgatttcagt
gagtcatgtcctctactggaaatgatgaccaataaggccatgaaacagagacactgggat
agaatctccgagttaactggaaccccatttgatgtggaatctgattctttttgccttaga
aatatcatggaagcaccactccttaaacataaggatgatattgaggatatttgcatatct
gccattaaggagaaggatatcgaagccaagctgactcaggtgattgagaattggaccaac
caaaatctgagttttgcagcatttaagggaaaaggagagctcctgctcaaaggaaccgaa
tcgggagaaattatcactttgatggaggatagtttaatggtcttagggtctttactcagc
aacagatacaatgctccatttaaaaaaaatatccagaattgggtgtataaattgtccact
tcctcagatataattgaagagtggctcgtagtacagaacctttgggtttatcttgaagcc
gtctttgtaggtggagatattgccaaacagctgcctcaggaagcaaaacgttttcagaat
attgacaagtcttggataaaaataatgcagcgagctcatgagaatcccaatgtgattaat
tgctgtgttggagatgaaaccatgggacaacttttacctcatttacatgagcagttggaa
gtatgtcagaagtcactcacagggtatttggagaagaaacgattactgtttccaagattc
ttctttgtatctgatccagttctcctggaaattcttggacaagccagtgattcccacacc
atacagccgcatctccctgcagtatctgacaacatcaatgaggtgacatttcatgcaaaa
gactatgatcgcatcatggccgtcatatcaagagaaggagaaaaaattgttttggataat
tctgttatggccaaaggtcctgtggagatttggctactggatttgttaaaaatgcagatg
tcatcattacataatataattagatccgctttctatcaaatcagtgattcaggatttcaa
ctcttaccattcctcagccactttccagcacaggttggacttctgggaattcagatgttg
tggacacacgattcagaagaggctttacgtaatgcaaaagatgacaggaaaatcatgcaa
gtgaccaatcagaaatttttggatattctaaatactctcattagtcagacaacacatgat
ctaagcaagtttgatagagtgaagttcgagactctaattaccatccatgtgcatcagaga
gatatttttgatgacttggtaaaaatgcatatcaaatcacctactgactttgaatggcta
aaacagagtagattttattttaaggaagatttggatcaaactgtggtgtctattacagat
gttgattttatttaccaaaatgaatttctgggatgtactgatcgtcttgttatcactcca
ttaacagatagatgctatatcacgttagctcaggccttgggcatgaacatgggaggtgct
cccgcaggacctgctggcactggcaaaacagaaaccacaaaagacatgggaaggtgtttg
ggaaaatatgtggtcgtgttcaattgctcagatcaaatggatttcagaggcctaggaagg
attttcaaaggtcttgcacagtcgggttcctggggctgttttgatgagtttaacagaatt
gaattgcctgtattatcagtggcagcacaacaaatttatattgttttgacagcaagaaaa
gaaagaaagaaacagttcattttttctgatggtgattgtgttgatttaaatccagaattt
ggaatcttcttaacgatgaaccctggatatgctgggcgccaggaactaccagaaaaccta
aaaatccagtttagaactgttgctatgatggttcctgatagacagatcattatgagagtt
aaacttgcaagctgtggttttcttgaaaatgttatcttggctcaaaaattttacgttctt
tacaaactctgtgaagagcaacttactaaacaggttcattatgactttggattgagaaat
attctgtctgtattgaggactcttggatctcaaaaaagagccagaccagaagatagtgaa
ttaagcattgtcatgagaggactaagagatatgaacctttccaaactggttgatgaagat
gaacccctgttcctcagcttaatcaatgacctgttcccaggactgcaactggatagtaat
acttatgcagaactgcaaaacgcagtagcccatcaggttcagatagagggtttgattaac
catccaccctggaacctgaaactcgtgcagttatatgagacgtctttggtacggcatggc
ttgatgactcttgggcccagtggttctggaaagacaaccgttatcacgattctaatgaag
gcgcaaacagaatgcggaaggcctcatagagaaatgcgaatgaatccaaaagccattact
gcacctcagatgtttggcagactggacactgctaccaatgactggacagatgggattttt
tctactctgtggagaaaaacattaaaagctaaaaaaggtgaaaacattttcctcatttta
gatggtcctgtggatgccatctggattgagaacttaaattccgttttggatgacaataaa
actctgacgttagctaatggagatcgcattcccatggcccctagttgtaagcttctgttt
gaagtccacaatatcgagaacgcctctcctgccacggtttctaggatgggcatggtctat
atcagcagctctgctctcagctggaggccaatcttacaggcatggttgaagaaacgcact
gcacaggaagctgctgtattcctgacactgtatgagaaagtctttgaagatacatacaca
tatatgaagctaaatctcaatcccaaaatgcagctcttggagtgcaactatattgtgcaa
tctctcaatcttctggaagggttaattccctccaaagaagaaggcggtgtttcctgtgtc
gaacatcttcataaattatttgtgtttggcctaatgtggagtttaggagcccttctggaa
ttagaaagcagagaaaagcttgaagccttcttacggcagcatgaaagcaagttggactta
ccagaaatacctaaaggctcaaatcaaaccatgtatgagttttatgttactgattatggt
gattgggagcactggaataagaaacttcagccttattattatccaactgacagtattccg
gaatattcatcaattttggttccaaatgttgacaatattagaacaaattttttgatagac
accattgcaaaacaacataaagctgttttgctcacaggagagcagggaactgcaaaaact
gtcatggttaaggcctatttgaaaaaatatgatcctgaagtacagctatccaaaagtcta
aacttttcatctgccacagaaccaatgatgtttcagagaacaattgaaagctacgtggat
aagcgaattggaagcacatatgggccaccaggagggagaaaaatgactgtatttattgat
gatattaatatgcctgtgattaatgagtggggagatcagataactaatgagattgtgcga
cagatgatggaaatggaaggaatgtacagcttggacaagcctggagacttcactactatt
gttgatgtgcagctcatagcagcaatgatccaccctggaggtggtcgaaatgatattcca
caacgtttaaaaagacaatttactgtgtttaattgtacattgccttcaaatgcttcaata
gacaaaatttttggaattattggatgtggatactttgatccttgtagaagtttcaagcct
caaatatgtgagatgattgtgaatttagtctcagtgggtagagtgctgtggcaatggact
aaggtgaagatgctgccaactccttctaaatttcattacatcttcaatcttcgagatctt
tccagaatttggcaaggaatgttgaccataaaagctgaggagtgcgcttcaatccctact
ctcctgtcccttttcaaacacgagtgcagcagagtaattgcagacagatttataactcct
gaagatgagcagtggtttaatgcacatcttactcgtgcagttgaagaaaatattggctct
gatgcagcgtcgtgtattcttcctgaaccatactttgtggattttcttcgtgagatgcca
gaaccaactggtgatgaacctgaagactctgtgtttgaagtacccaaaatatatgaattg
atgccatcctttgactttctggctgaaaaactccagttttaccagagacagttcaatgaa
atcattagaggaacatctcttgatctggtgttttttaaagatgcaatgactcatcttatt
aagatttcacgaataattcgaacgtcgtgtggaaatgcattgctggtgggtgttggtggt
tccggaaaacaaagtctttcaagattggcctcttttattgctggctatcaaatattccag
ataacattaaccaggtcttacaatgtgactaatctaacagatgatttaaaagctttgtac
aaagttgctggtgctgatggaaaaggcatcactttcatctttactgacagtgaaataaaa
gatgaggcatttctagaataccttaacaacttgctatcttcaggggagatctccaacttg
tttgcacgagatgagatggatgaaatcacccaaggtctgatttcagtgatgaagagggag
ctacctcgccatcctcctacctttgataatttgtatgaatacttcatttcaagatcaagg
aagaacttacatgttgttctctgcttttctccagttggtgagaagttccgtgcccgttct
ttgaaatttcctggcttgatatcaggttgcactatggactggttcagccgctggccaagg
gaggctctgattgctgtggcctcctacttcctttcagactataatattgtctgctctagt
gaaattaaaagacaagttgtagaaacaatgggcctgtttcatgacatggtttcagagagc
tgtgaaagttatttccaaagataccgccgaagagcacatgtgactcccaaatcttacctc
tcatttataaatggttataaaaacatttatgctgaaaaggtgaagttcattaatgaacag
gctgaacgtatgaatattggtcttgataaactaatggaggcaagtgaatctgttgctaaa
ctctctcaggatcttgcagtcaaggagaaggagttggcagtggcttccataaaagcagac
gaagtattagcagaagtcacagtaagcgctcaggcttcagccaaaattaaaaatgaagta
caggaggtaaaggacaaagcccaaaaaattgtggatgaaattgatagtgaaaaagtgaaa
gctgaaagcaagcttgaggcagctaaacctgcactggaagaagcagaagcagccctgaat
actatcaagccaaatgatattgccacagtcaggaaacttgcaaaaccaccacatcttatt
atgagaatcatggactgtgttctgttactatttcaaaagaaaattgaccctgttactatg
gatccagaaaaatcttgctgtaagccatcatggggagagtcattaaagttgatgagtgca
acaggattcctgtggagccttcagcagttccctaaggacactataaatgaagagactgtt
gagttactacagccatattttaatatggatgattatacttttgaaagtgccaaaaaagtc
tgtgggaatgtggctggtctcctgtcttggacacttgctatggcaatattttatggcatc
aatagagaagtgttgcctctgaaggccaacctggccaagcaggaaggccggttagcagtt
gctaatgctgagttagggaaggcacaagccctgctggatgagaagcaagctgagctggat
aaagtacaggcaaaatttgatgcagcaatgaatgagaaaatggatttgcttaatgacgct
gatacgtgccggaaaaagatgcaggccgcctccactctcatcgatgggctgagtggagaa
aaaatccggtggacccagcaaagtaaagaattcaaagctcagattaatagacttgtaggt
gatattctgctgtgcacgggattcctttcctaccttggtcctttcaatcagatatttagg
aactatttgcttaaagatcaatgggaaatggagttgagagcacggaaaattcctttcaca
gaaaacctgaatcttatttcaatgttggtggatcctccaactattggtgagtgggggcta
cagggattaccaggagatgatctctcaattcagaatggcattattgtgacaaaggccacc
agatacccactcctcatagacccacaaactcaaggcaaaacttggattaaatcaaaggaa
aaagaaaatgatttacaggtgacatctctgaaccataaatattttcgcacacacttggag
gacagcctttccttgggccgaccccttctcattgaggacattcatgaagagctggatcca
gccttggataatgtattagaaaagaattttattaaatctggcaccactttcaaggtgaaa
gtcggtgataaggaatgtgatatcatggatacatttaaactttacattactacgaagtta
ccaaatcctgcctttaccccagagattaatgctaaaacgtcagtcattgatttcactgtt
acaatgaaaggacttgagaatcagttactaaggagagtcattctaacagagaaacaggag
ttagaggctgagagggttaaacttttggaggatgttacttttaataagcggaagatgaaa
gaacttgaagataacctcctctataaattaagtgctacaaaaggctcattggtagatgac
gaatctctcattggtgtacttcgaactaccaagcagacagcagctgaggtaagtgaaaag
ttgcatgtggctgcagaaactgagatcaagatcaacgcggctcaggaggagttccggccc
gcagccacccgcggaagcatcctctacttcctcatcacagagatgagcatggtcaacatc
atgtatcagacgtcattggcccagttcttgaagttatttgaccagtccatggccagatct
gaaaagtcaccactacctcaaaagagaattacaaatattatcgagtacctgacatatgaa
gtttttacatactctgtcagaggcctatacgaaaaccacaaattcctgtttgtactcctc
atgaccttaaagattgaccttcagagagggacagttaagcacagagagtttcaagctctc
attaaagggggagcagctctggacctgaaagcctgtcctcccaaaccctatcgctggatc
cttgacatgacttggctgaatcttgtggagctgagtaaacttccacaatttgcagaaatt
atgaaccagatatctcgtaatgagaaggggtggaaaagctggtttgataaagatgctcca
gaggaggaaattatccctgatggatataatgattcactagatacctgccataaactttta
cttatcaggtcttggtgcccagaccgtactgtttttcaagcaagaaagtatattgcagat
tctttggaggagaagtacacagaaccagttatcttaaatctggagaaaacttgggaagaa
agtgatacccggacacctctgatatgcttcctgtccatgggatctgaccccaccaatcaa
attgatgcattggccaagaaactgaaactggaatgtagaactatctcaatggggcaagga
caagaagtacatgctcgaaagctgattcagatgtcaatgcagcagggtggttgggtatta
ctacaaaattgccaccttggcctggaattcatggaagaattactagagacgctaattacc
actgaagccagtgatgattctttccgagtatggataactacggagccccatgatcgattt
ccaattacattgcttcagacctctctcaaattcactaatgagccaccccaaggtgtacgc
gcaggtttgaaaagaacatttgctggaattaatcaagaccttctggacatcagtaattta
cccatgtggaagccgatgctttacacagtagcatttttacactccactgtgcaggagcga
cgaaaatttggccccttaggatggaatattccctacgaattcaattctgctgacttttca
gccagtgttcagtttattcagaatcaccttgatgaatgcgatattaagaaaggtgtatca
tggaatacggttcggtacatgatcggagaagtacaatatggaggcagagtgacagatgac
tttgacaaacgtctacttaattgctttgccagagtctggttcagtgagaagatgtttgaa
ccgtcattctgcttttatactggatataaaatccccttatgcaaaaccttagaccagtat
tttgaatacatccagtcactgccatccctagataaccctgaagtctttgggcttcaccct
aatgctgatatcacgtatcagagtaacactgcttctgctgttcttgaaacaattaccaac
attcaacccaaagagagtggaggtggtgtgggagagacccgggaggctattgtttataga
ttatctgaagatatgctgagtaaactccctcctgattacattcctcatgaggtgaaatct
cgtttgataaagatgggccatcttaattcaatgaacatatttcttagacaagaaattgac
agaatgcaaagagtcatttcaatactccgcagtagcctgagtgatctaaaattggccatt
gaaggaacaatcattatgagtgagaatctgagagatgctctggacaacatgtatgatgct
cgtatacctcagctctggaaaagagtgtcttgggattcgtccacactgggcttctggttc
actgaacttttggaaagaaatgctcagttttctacgtggatatttgaagggaggcctaat
gtgttttggatgactggtttctttaatccccaaggcttcctcacagcaatgaggcaagaa
gtgacccgtgcccacaaaggctgggcactggacactgtgaccatccacaatgaagttctg
agacagaccaaggaggagatcacgtcaccccctggggaaggtgtgtatatttatgggctc
tacatggatggagcagcctgggacagacggaatgggaagctcatggaatccacccccaag
gtactcttcacgcagttacccgtgctccacatctttgccattaactccacggcacccaag
gaccccaagctgtatgtgtgtcctatttacaagaaacccaggcgaactgatttgaccttc
atcactgtggtatatttacgaacagtgttgtccccggatcactggatcctgagaggagtg
gcccttttgtgtgacatcaagtaa

KEGG   Homo sapiens (human): 1770Help
Entry
1770              CDS       T01001                                 

Gene name
DNAH9, CILD40, DNAH17L, DNEL1, DYH9, Dnahc9, HL-20, HL20
Definition
(RefSeq) dynein axonemal heavy chain 9
  KO
K10408  dynein heavy chain, axonemal
Organism
hsa  Homo sapiens (human)
Pathway
hsa05016  Huntington disease
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09164 Neurodegenerative disease
   05016 Huntington disease
    1770 (DNAH9)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    1770 (DNAH9)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    Dyneins
     1770 (DNAH9)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: MT DHC_N1 AAA_6 DHC_N2 AAA_8 Dynein_C AAA_9 AAA_7 AAA_lid_11 AAA_lid_1 Dynein_heavy Dynein_AAA_lid AAA_5 AAA_16 AAA_30 Sigma54_activat AAA_19 DUF1672
Motif
Other DBs
NCBI-GeneID: 1770
NCBI-ProteinID: NP_001363
OMIM: 603330
HGNC: 2953
Ensembl: ENSG00000007174
Vega: OTTHUMG00000130383
Pharos: Q9NYC9(Tbio)
UniProt: Q9NYC9
Position
17p12
AA seq 4486 aa AA seqDB search
MRLAEERAALAAENADGEPGADRRLRLLGTYVAMSLRPAAGAWERCAGSAEAEQLLQAFL
GRDAAEGPRPLLVVRPGPRGLAIRPGLEVGPESGLAGAKALFFLRTGPEPPGPDSFRGAV
VCGDLPAAPLEHLAALFSEVVLPVLANEKNRLNWPHMICEDVRRHAHSLQCDLSVILEQV
KGKTLLPLPAGSEKMEFADSKSETVLDSIDKSVIYAIESAVIKWSYQVQVVLKRESSQPL
LQGENPTPKVELEFWKSRYEDLKYIYNQLRTITVRGMAKLLDKLQSSYFPAFKAMYRDVV
AALAEAQDIHVHLIPLQRHLEALENAEFPEVKPQLRPLLHVVCLIWATCKSYRSPGRLTV
LLQEICNLLIQQASNYLSPEDLLRSEVEESQRKLQVVSDTLSFFKQEFQDRRENLHTYFK
ENQEVKEWDFQSSLVFVRLDGFLGQLHVVEGLLKTALDFHKLGKVEFSGVRGNALSQQVQ
QMHEEFQEMYRLLSGSSSDCLYLQSTDFENDVSEFNQKVEDLDRRLGTIFIQAFDDAPGL
EHAFKLLDIAGNLLERPLVARDTSDKYLVLIQMFNKDLDAVRMIYSQHVQEEAELGFSPV
HKNMPTVAGGLRWAQELRQRIQGPFSNFGRITHPCMESAEGKRMQQKYEDMLSLLEKYET
RLYEDWCRTVSEKSQYNLSQPLLKRDPETKEITINFNPQLISVLKEMSYLEPREMKHMPE
TAAAMFSSRDFYRQLVANLELMANWYNKVMKTLLEVEFPLVEEELQNIDLRLRAAEETLN
WKTEGICDYVTEITSSIHDLEQRIQKTKDNVEEIQNIMKTWVTPIFKTKDGKRESLLSLD
DRHDRMEKYYNLIKESGLKIHALVQENLGLFSADPTSNIWKTYVNSIDNLLLNGFFLAIE
CSLKYLLENTECKAGLTPIFEAQLSLAIPELVFYPSLESGVKGGFCDIVEGLITSIFRIP
SLVPRLSPQNGSPHYQVDLDGIPDLANMRRTLMERVQRMMGLCCGYQSTFSQYSYLYVED
RKEVLGQFLLYGHILTPEEIEDHVEDGIPENPPLLSQFKVQIDSYETLYEEVCRLEPIKV
FDGWMKIDIRPFKASLLNIIKRWSLLFKQHLVDHVTHSLANLDAFIKKSESGLLKKVEKG
DFQGLVEIMGHLMAVKERQSNTDEMFEPLKQTIELLKTYEQELPETVFKQLEELPEKWNN
IKKVAITVKQQVAPLQANEVTLLRQRCTAFDAEQQQFWEQFHKEAPFRFDSIHPHQMLDA
RHIEIQQMESTMASISESASLFEVNVPDYKQLRQCRKEVCQLKELWDTIGMVTSSIHAWE
TTPWRNINVEAMELECKQFARHIRNLDKEVRAWDAFTGLESTVWNTLSSLRAVAELQNPA
IRERHWRQLMQATGVSFTMDQDTTLAHLLQLQLHHYEDEVRGIVDKAAKEMGMEKTLKEL
QTTWAGMEFQYEPHPRTNVPLLCSDEDLIEVLEDNQVQLQNLVMSKYVAFFLEEVSGWQK
KLSTVDAVISIWFEVQRTWTHLESIFTGSEDIRAQLPQDSKRFEGIDIDFKELAYDAQKI
PNVVQTTNKPGLYEKLEDIQGRLCLCEKALAEYLDTKRLAFPRFYFLSSSDLLDILSNGT
APQQVQRHLSKLFDNMAKMRFQLDASGEPTKTSLGMYSKEEEYVAFSEPCDCSGQVEIWL
NHVLGHMKATVRHEMTEGVTAYEEKPREQWLFDHPAQVALTCTQIWWTTEVGMAFARLEE
GYESAMKDYYKKQVAQLKTLITMLIGQLSKGDRQKIMTICTIDVHARDVVAKMIAQKVDN
AQAFLWLSQLRHRWDDEVKHCFANICDAQFLYSYEYLGNTPRLVITPLTDRCYITLTQSL
HLTMSGAPAGPAGTGKTETTKDLGRALGILVYVFNCSEQMDYKSCGNIYKGLAQTGAWGC
FDEFNRISVEVLSVVAVQVKSIQDAIRDKKQWFSFLGEEISLNPSVGIFITMNPGYAGRT
ELPENLKSLFRPCAMVVPDFELICEIMLVAEGFIEAQSLARKFITLYQLCKELLSKQDHY
DWGLRAIKSVLVVAGSLKRGDPDRPEDQVLMRSLRDFNIPKIVTDDMPIFMGLIGDLFPA
LDVPRRRDPNFEALVRKAIVDLKLQAEDNFVLKVVQLEELLAVRHSVFVVGGAGTGKSQV
LRSLHKTYQIMKRRPVWTDLNPKAVTNDELFGIINPATGEWKDGLFSSIMRELANITHDG
PKWILLDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNPTMKLLFEISHLRTATPATVS
RAGILYINPADLGWNPPVSSWIEKREIQTERANLTILFDKYLPTCLDTLRTRFKKIIPIP
EQSMVQMVCHLLECLLTTEDIPADCPKEIYEHYFVFAAIWAFGGAMVQDQLVDYRAEFSK
WWLTEFKTVKFPSQGTIFDYYIDPETKKFEPWSKLVPQFEFDPEMPLQACLVHTSETIRV
CYFMERLMARQRPVMLVGTAGTGKSVLVGAKLASLDPEAYLVKNVPFNYYTTSAMLQAVL
EKPLEKKAGRNYGPPGNKKLIYFIDDMNMPEVDAYGTVQPHTIIRQHLDYGHWYDRSKLS
LKEITNVQYVSCMNPTAGSFTINPRLQRHFSVFVLSFPGADALSSIYSIILTQHLKLGNF
PASLQKSIPPLIDLALAFHQKIATTFLPTGIKFHYIFNLRDFANIFQGILFSSVECVKST
WDLIRLYLHESNRVYRDKMVEEKDFDLFDKIQTEVLKKTFDDIEDPVEQTQSPNLYCHFA
NGIGEPKYMPVQSWELLTQTLVEALENHNEVNTVMDLVLFEDAMRHVCHINRILESPRGN
ALLVGVGGSGKQSLTRLAAFISSMDVFQITLRKGYQIQDFKMDLASLCLKAGVKNLNTVF
LMTDAQVADERFLVLINDLLASGEIPDLYSDDEVENIISNVRNEVKSQGLVDNRENCWKF
FIDRIRRQLKVTLCFSPVGNKLRVRSRKFPAIVNCTAIHWFHEWPQQALESVSLRFLQNT
EGIEPTVKQSISKFMAFVHTSVNQTSQSYLSNEQRYNYTTPKSFLEFIRLYQSLLHRHRK
ELKCKTERLENGLLKLHSTSAQVDDLKAKLAAQEVELKQKNEDADKLIQVVGVETDKVSR
EKAMADEEEQKVAVIMLEVKQKQKDCEEDLAKAEPALTAAQAALNTLNKTNLTELKSFGS
PPLAVSNVSAAVMVLMAPRGRVPKDRSWKAAKVTMAKVDGFLDSLINFNKENIHENCLKA
IRPYLQDPEFNPEFVATKSYAAAGLCSWVINIVRFYEVFCDVEPKRQALNKATADLTAAQ
EKLAAIKAKIAHLNENLAKLTARFEKATADKLKCQQEAEVTAVTISLANRLVGGLASENV
RWADAVQNFKQQERTLCGDILLITAFISYLGFFTKKYRQSLLDRTWRPYLSQLKTPIPVT
PALDPLRMLMDDADVAAWQNEGLPADRMSVENATILINCERWPLMVDPQLQGIKWIKNKY
GEDLRVTQIGQKGYLQIIEQALEAGAVVLIENLEESIDPVLGPLLGREVIKKGRFIKIGD
KECEYNPKFRLILHTKLANPHYQPELQAQATLINFTVTRDGLEDQLLAAVVSMERPDLEQ
LKSDLTKQQNGFKITLKTLEDSLLSRLSSASGNFLGETVLVENLEITKQTAAEVEKKVQE
AKVTEVKINEAREHYRPAAARASLLYFIMNDLSKIHPMYQFSLKAFSIVFQKAVERAAPD
ESLRERVANLIDSITFSVYQYTIRGLFECDKLTYLAQLTFQILLMNREVNAVELDFLLRS
PVQTGTASPVEFLSHQAWGAVKVLSSMEEFSNLDRDIEGSAKSWKKFVESECPEKEKLPQ
EWKNKTALQRLCMLRAMRPDRMTYALRDFVEEKLGSKYVVGRALDFATSFEESGPATPMF
FILSPGVDPLKDVESQGRKLGYTFNNQNFHNVSLGQGQEVVAEAALDLAAKKGHWVILQN
IHLVAKWLSTLEKKLEEHSENSHPEFRVFMSAEPAPSPEGHIIPQGILENSIKITNEPPT
GMHANLHKALDNFTQDTLEMCSRETEFKSILFALCYFHAVVAERRKFGPQGWNRSYPFNT
GDLTISVNVLYNFLEANAKVPYDDLRYLFGEIMYGGHITDDWDRRLCRTYLGEFIRPEML
EGELSLAPGFPLPGNMDYNGYHQYIDAELPPESPYLYGLHPNAEIGFLTQTSEKLFRTVL
ELQPRDSQARDGAGATREEKVKALLEEILERVTDEFNIPELMAKVEERTPYIVVAFQECG
RMNILTREIQRSLRELELGLKGELTMTSHMENLQNALYFDMVPESWARRAYPSTAGLAAW
FPDLLNRIKELEAWTGDFTMPSTVWLTGFFNPQSFLTAIMQSTARKNEWPLDQMALQCDM
TKKNREEFRSPPREGAYIHGLFMEGACWDTQAGIITEAKLKDLTPPMPVMFIKAIPADKQ
DCRSVYSCPVYKTSQRGPTYVWTFNLKTKENPSKWVLAGVALLLQI
NT seq 13461 nt NT seq  +upstreamnt  +downstreamnt
atgcggctcgcggaggagcgggccgcgctcgcggcggagaacgcggatggggaacccggc
gccgaccgacgactgcgactcctggggacctacgtggccatgagcctgcggccggctgcg
ggcgcctgggagcgttgcgcggggagtgctgaggcggagcagctgctccaggccttcctg
ggccgcgatgctgccgaggggccgcggccgctgctggtggtgcggcccgggcccaggggc
ctggcaatacgccccgggctggaggtgggacctgagtcgggcctggctggcgctaaggcg
ctttttttccttcgcaccgggcccgagcctccagggcccgacagcttccgcggcgcagtg
gtctgcggggacctgcccgcggcacctctggagcacctagccgcgctgttctcggaggtt
gttctacccgtcctggccaatgagaagaatcgcctaaactggccccacatgatatgtgag
gatgtcaggcggcacgcccacagcctccaatgtgacctctcagttatacttgagcaagtg
aagggaaaaactttgctgcctcttccagcaggctcagaaaaaatggagtttgcggattcc
aaaagtgagacagtcttggattctatagataagtcagtcatctatgccattgagtctgca
gtgatcaaatggagctaccaagtccaggtggtactcaagagagagtcttcccagccactc
ttacaaggggagaatcccacccctaaggtggagttggagttctggaagagcaggtatgaa
gatctgaaatacatctataatcaactgagaacaataacggtgaggggcatggccaagctc
ctggacaagcttcagagtagctactttccagctttcaaagccatgtacagagatgttgtt
gcagctctagcagaggcacaggacatccatgtgcacctgataccgctccagcgccacctg
gaagctctggagaatgcagaatttccggaggtgaagccccagctgcggcccctgctccac
gtggtctgtctgatttgggccacatgcaagtcctaccgctccccgggaaggctgactgtg
ctgctccaggagatttgcaaccttctcatccagcaggcctctaattatctcagcccagaa
gacctgctgagaagtgaggtagaagaaagtcagagaaaactgcaagtggtctcagacact
ttgagcttcttcaagcaagagtttcaggacagaagggagaatctccacacttacttcaaa
gagaaccaggaagtcaaggaatgggatttccagtcttctttggtctttgtgcgattggat
ggcttcctgggacaactgcacgtggtggagggtcttctgaagacggccctggatttccac
aaactgggaaaggtggagttcagcggcgtcagagggaatgctctgagtcagcaggtccag
caaatgcatgaagaatttcaagagatgtacaggcttctctcaggatcctcctccgactgc
ctgtacctccaaagcacggactttgaaaatgacgtctctgaatttaaccagaaagtagaa
gatcttgaccgaagattggggactatctttattcaagcttttgatgatgcacctggcttg
gagcatgcctttaagctgctagacatagcaggaaacctccttgaaagaccgctggtagcg
agggatacatctgataaatacctggtcctcatccaaatgttcaacaaagatctggatgca
gtgaggatgatctacagtcagcacgtccaggaggaagcagaacttgggttctccccggtg
cacaagaacatgcccaccgtggctggcggcctccgctgggcacaggagctgaggcagcgc
atccagggtcctttcagcaactttggacgcatcacacacccttgcatggaatctgcagaa
ggaaagcgaatgcaacaaaaatatgaagatatgctgtcattgctagaaaagtatgagaca
agactttatgaggattggtgccggacagtatcagagaagtcacagtacaatctttcccaa
ccacttctaaaacgtgacccagagacgaaggagatcactatcaactttaacccacagctg
atttcagtgctgaaagaaatgagctatcttgaacccagagagatgaaacacatgcctgag
acagcagcagccatgttctcctccagggatttctatcggcagcttgtggctaatttagag
ttgatggcaaattggtacaacaaggttatgaaaactctgctggaggtggaatttccatta
gtggaggaagagctgcaaaatattgatctccgcctcagagcagcagaggagactttgaac
tggaaaacagaaggcatttgcgattatgtcactgaaatcaccagtagtattcatgatctt
gaacaaagaattcagaaaactaaagacaatgtggaagagatccaaaacatcatgaaaaca
tgggtgactccaatatttaagacaaaagatggaaaaagggaatcccttctttctctggat
gatcggcatgatcgaatggaaaaatattacaatctcatcaaggaatctggccttaagatc
cacgcccttgttcaggaaaacctgggtctattttcagcagacccaacctccaatatctgg
aagacttatgttaactctattgacaatttgttgctgaatggattctttcttgccattgag
tgctccctcaagtatcttctggaaaatactgagtgtaaggcaggacttaccccaatattt
gaagcacaactgagtctagccatcccagagctagttttctatccgtctctggagtctgga
gtgaaggggggtttctgtgacattgttgagggtctcatcaccagcatttttaggatacca
tctctggtgccacggctttccccacaaaatggctctcctcactatcaggtcgacctggac
ggtataccagatttggcaaacatgcggcgcacactcatggagagagtccagagaatgatg
ggcctctgctgtggctatcagagcaccttcagccagtattcgtacctctatgtggaggac
cggaaggaggttctgggtcagtttctgctgtacgggcacatcctcactccggaagaaatt
gaagaccatgtggaagatggcatcccagagaaccctcccctcctttctcagtttaaagtg
caaatcgactcctatgaaacgctctatgaagaggtgtgcaggctggaacccatcaaggtg
tttgacggctggatgaaaattgatattcgaccctttaaggcatctctgctgaatattatt
aagaggtggagcctcctgttcaaacagcatcttgtggaccacgtcactcacagcttggcc
aacctggatgcgtttataaagaagagtgagagcggcttactcaagaaagttgaaaaagga
gatttccaaggcttggttgagatcatgggacaccttatggctgttaaagaacggcagagt
aacactgatgagatgtttgagcccttaaagcagactattgaattgctgaagacctatgaa
caagaattgccagaaacagtgtttaagcagctggaggagctgcctgagaaatggaacaac
ataaaaaaggtggccattactgtgaagcagcaggtggccccactgcaggcaaatgaagtg
acactcctccgccagaggtgcacagccttcgatgcagaacagcagcaattctgggagcaa
ttccacaaagaagccccgttcaggtttgatagcatccaccctcatcaaatgctggatgcc
aggcacatcgagatccagcagatggaatccactatggcctccatttctgagtctgccagc
ttatttgaagtcaatgtccctgactataagcagctgaggcagtgcaggaaggaggtctgc
cagctgaaggagctctgggacaccattggaatggtgacctccagcatccatgcctgggag
accacaccctggaggaatatcaacgtggaagccatggagttggagtgcaaacagtttgcc
cggcatatccgaaacctggacaaggaggtcagggcctgggatgcattcacaggcctggaa
agcactgtgtggaacacgctgagctccctgagggcagtagctgagctgcagaatccagcc
atccgggagcggcactggaggcagctgatgcaggccaccggtgtgagcttcactatggac
caggacaccaccctagcgcacctgctgcagctccagctgcaccactatgaggatgaggtc
cggggcattgtggacaaagctgcaaaagagatgggtatggagaaaaccttaaaggagctg
cagactacctgggctggcatggaattccagtatgagccccacccacggaccaatgtcccc
ctcctgtgctctgatgaggacctcatagaggttctggaggataatcaagttcaacttcag
aacctggtgatgtccaagtatgttgctttcttcttggaggaggtgtcgggctggcagaag
aagctgtccacagtggacgctgtcatctctatctggtttgaagtgcagcgaacatggact
cacctggaaagcatattcactggatctgaagatattcgggcacagctaccccaggattct
aaaaggtttgaaggcatcgacattgactttaaagagctagcttatgatgcccagaaaatt
ccaaatgtagtgcaaaccaccaacaagccaggcctgtatgaaaagctggaggatattcag
ggcagattgtgcctgtgtgagaaggccctggcagagtacctcgacaccaagaggcttgcc
ttcccgcggttttactttctctcctcctccgatctgttagacatcctttccaacggcaca
gctccacaacaggttcaacgtcacctttccaaactctttgacaacatggccaagatgcga
ttccagctagatgccagtggggaaccaaccaagacaagcctcggcatgtacagcaaagaa
gaggagtatgtggctttcagtgagccctgtgactgcagcgggcaggtagaaatatggctg
aaccatgtccttggtcacatgaaggccactgtgaggcatgagatgacagaaggtgtaact
gcctatgaagaaaagccgagggagcagtggctttttgaccacccagctcaggtggccctg
acctgtactcagatctggtggacaacagaagtgggcatggcatttgccaggctggaggaa
ggctatgagagtgccatgaaggactattataagaagcaagtggcccagctcaaaaccctt
atcaccatgctgattggccagctctccaagggagaccggcagaagattatgactatatgc
accatcgatgtgcatgcccgggatgtggtagccaagatgattgctcagaaggtagacaat
gcccaggctttcctctggctgtctcagctgcgccatcgttgggatgacgaggtcaaacac
tgctttgccaacatctgtgatgcccagtttttgtattcctatgagtacctgggaaacaca
cctcgcttggtgatcacacctttgactgacaggtgctacatcaccctcacccagtccctg
cacctgaccatgagtggggctcccgcaggacctgcaggcacaggcaagaccgagaccacc
aaggacctgggccgcgcactgggcatcctggtctatgtgttcaactgctcggagcagatg
gattacaagtcttgtggcaacatctacaaaggccttgctcagactggtgcctggggctgc
tttgatgagtttaatcgaatctccgtggaggtcttgtcagtggtggcagtgcaggtaaaa
agcattcaagatgcgattagagataagaagcagtggttcagcttccttggggaggagatc
agcctgaatccttctgtcggtatcttcatcaccatgaacccaggctatgctggccgcaca
gagctgccagagaatctcaagtctctcttcaggccttgtgcaatggtggttccagacttt
gaattgatctgtgaaatcatgctggtggcagaaggattcattgaagcccagtcattagcc
agaaagttcatcactctttaccagttgtgcaaagagcttctctccaaacaggatcactac
gactggggcctacgggccatcaagtccgtgctggtggtggcaggatccctgaagagagga
gaccctgaccggcctgaggaccaggtcctgatgcgctccttgcgggatttcaacatcccc
aagattgtgactgatgacatgcccatcttcatgggcctgatcggggacctctttcccgcc
ctggatgtcccccggaggagagaccccaacttcgaagctttggttaggaaggcgatagtg
gatctgaagctccaggctgaggacaactttgtgctcaaggtggtccagctggaggagctc
ctggctgtgcggcactctgtatttgtggtgggtggcgctggtaccggcaagtcacaggtg
ctgaggtccttgcacaagacctatcagatcatgaaacggcgccccgtctggactgacctc
aatcccaaagcagtcacaaatgatgagctctttggcatcatcaatccagccacaggagaa
tggaaggatggattgttctcttccatcatgcgggagcttgccaacatcacccatgatggg
cccaagtggattttactggatggcgacatagatccaatgtggattgaatccctgaatact
gtcatggatgataacaaggtgctgacattggccagcaatgagaggattcctctgaacccc
accatgaagctcctctttgagatcagccacctgcgcacagccactccagcaactgtctct
agagcagggatcttgtacatcaacccggcagacttgggatggaaccctccagtgagcagc
tggattgagaagagggaaatccagacagagagagccaacttaaccattttgttcgacaag
tatcttccaacctgcctagacacactcagaaccaggtttaagaagatcattcccatccca
gagcagagcatggttcagatggtgtgtcaccttctggaatgtctcctgaccacggaggac
atccctgcagactgccctaaggaaatttatgagcattattttgtgtttgctgccatctgg
gctttcggcggagcaatggtccaagatcagcttgtggactaccgggcagagttcagcaaa
tggtggctgactgagttcaaaacagtcaagtttccttcccaaggaaccatctttgactat
tacatcgacccagagaccaagaaattcgagccttggtccaagctcgtcccccagttcgaa
tttgaccccgagatgcccttgcaggcgtgtttggtgcacacgagtgagaccatccgtgtg
tgctacttcatggagcggttgatggcgcggcagcggcctgtcatgctggtgggcacggct
ggcactggcaagtcggtgctggtgggagctaagctggccagccttgaccccgaggcatac
ctggtgaaaaacgtgccattcaactactacaccacgtcagcaatgctgcaggctgtcctg
gagaagcctctggaaaagaaggctggcagaaactatggccctccagggaacaagaaactc
atctatttcattgatgacatgaacatgcctgaggtggatgcctacgggacggtgcagccc
cacaccatcatccggcagcatctggactatggccactggtatgatcggagcaagctgtcc
ctaaaggagatcacaaatgtacagtatgtttcctgtatgaaccccacggcaggcagcttc
accatcaacccccggcttcagcgtcacttcagcgtgtttgtcctctccttcccgggggca
gatgccctgtcctctatctacagcatcatcctcactcagcatctgaagctcggaaacttc
ccggcgtccctgcagaaatccatccccccactgatcgatctggccctcgccttccaccag
aaaattgctaccaccttcctacccacaggaatcaaattccactacatcttcaacctcaga
gattttgccaacattttccagggcattctcttctcctcagtggaatgtgtgaaatccaca
tgggatcttataaggctctatctgcatgaatcaaatcgagtttatcgggataagatggta
gaagaaaaggactttgatctttttgataaaatccagacagaagtgctcaagaaaactttt
gatgatattgaagaccctgtggagcagacccaaagcccgaacctgtattgtcactttgca
aatggtattggggagcccaaatacatgcctgtacagtcttgggaacttttgacccagact
ctggtggaggccttggagaaccacaatgaagtcaacacagtgatggacctagttctcttt
gaggatgccatgcgccatgtctgccatatcaatcgcatcttggagtccccgcggggaaat
gctctgctggttggtgtaggtgggagcggcaagcagagcctgacaaggctggcagctttc
atcagctccatggatgtcttccagatcacactgcgcaaaggctaccagatccaggacttc
aagatggacctggccagcctgtgtctgaaagctggagtgaagaatctcaacacagtgttt
ctcatgactgatgcccaagtggctgatgagaggttccttgtgctcatcaatgatcttttg
gcatctggggagatcccagatctctactctgatgatgaagttgaaaacatcataagcaat
gtgaggaatgaagtcaagagccagggtctggttgacaacagagagaactgttggaagttc
tttatagatcggatccggcgacagctgaaggtgactctctgtttctcccctgtgggaaac
aagctaagagtccgcagcaggaagttcccagccattgtgaactgcacagccatccactgg
ttccacgagtggcctcagcaagcattggagtctgtcagcctccgcttcttgcagaacaca
gagggcattgagcccacagtaaagcagtcgattagcaaattcatggcctttgtccacaca
agtgtcaaccaaacatcccagtcttatctgagcaatgaacagcgctacaactatacaact
cccaagtcctttctggagttcatcagactctaccagagcttgttgcacaggcacagaaaa
gagctcaagtgcaagacagagcggttggagaacgggctgctgaagctgcatagcacctct
gcccaggtggatgatctgaaagcaaagctggctgcccaggaagtagagctgaagcagaaa
aatgaagatgcagacaaactgattcaggtcgtgggtgtggagactgacaaagtgagcaga
gagaaagccatggcagatgaagaggagcagaaggtggccgtcatcatgctagaggtgaaa
cagaagcagaaggactgtgaggaggacctggcaaaggctgagccagcactcacagcagcg
caggcagctctcaacaccctgaacaagaccaacctgacagagctgaagtcatttggctct
ccgcctctggccgtcagcaatgtcagcgctgcggtgatggtactgatggctcccaggggt
agggtgcccaaggaccggagctggaaggctgctaaggtcaccatggccaaagtggatggc
ttcctggactcgctaataaacttcaacaaagagaacattcacgagaactgcctcaaagcc
atcaggccgtatctgcaagaccccgagttcaatcctgagtttgtggccaccaaatcctat
gcggctgcaggcctctgctcctgggtcatcaatattgtgagattttatgaggtgttctgt
gatgtggaacccaagcgccaggcactgaacaaagccaccgcggacctcacagctgcccag
gagaagctggctgccatcaaagccaagatcgctcaccttaatgaaaacctggcaaagctc
acagccaggtttgagaaagcaacagcagacaaactcaaatgtcagcaagaagccgaagtg
accgcagtcaccatctcccttgccaaccgcctggttggaggactcgcttctgaaaacgtg
aggtgggcagatgccgtgcagaacttcaaacagcaggaaaggacgttatgtggagacatt
ttacttataacggctttcatttcctaccttggcttcttcacaaagaaataccggcagagc
ctcctggacagaacttggaggccctacctgagccagctgaaaactcccattccagtcacc
ccagccctggatcccctgaggatgctgatggatgatgctgacgtggctgcctggcagaac
gagggcctcccagccgaccgcatgtccgtggagaatgccaccattctcatcaactgtgag
cgctggccactcatggttgaccctcagctacaaggcatcaaatggatcaagaataaatat
ggtgaagatctccgggtcacgcagattggtcagaaaggctaccttcaaatcatagagcag
gccctggaagctggagctgtggtgctgattgaaaatctagaggagtccattgatcctgtt
ctgggacccctgcttgggagagaagtcattaaaaaaggacgattcattaaaattggagac
aaagaatgtgaatacaatcccaagttccggctcatcctccacaccaagctggctaatcct
cactaccagcctgagctgcaggctcaggccaccctgatcaacttcaccgtgaccagggat
ggcctggaggaccagttgctggccgctgtggtcagcatggagaggccagacttggagcag
ctgaagtccgatctcacaaagcagcagaatggattcaaaattaccctgaaaacgttggaa
gacagtcttctctctcgcctctcctccgcctctgggaacttcctgggagaaacagtgctg
gtggaaaacctagagatcaccaagcagactgctgccgaagttgagaaaaaggtccaggag
gccaaggtgactgaagtgaaaatcaacgaggcccgagagcactaccggccagcagctgcc
agggcctcactgctctacttcatcatgaacgacctcagcaagatccatccaatgtaccag
ttttctctcaaggccttcagtatcgtcttccagaaggctgtggagagggctgctcctgac
gaaagcctcagggagcgggtggccaacctaatagacagcataaccttctctgtgtaccag
tacaccatccgcgggctctttgagtgtgataagctgacctaccttgcccagctcaccttt
cagattctcctcatgaaccgagaagtcaatgcagtggagttggatttcctgcttcgatct
ccagtgcagacgggcaccgccagccccgtggagttcctctcccatcaggcgtggggagct
gtcaaggtactttcatcaatggaagaattctctaatctggatcgggacatagagggatct
gctaagagctggaaaaagtttgtggagtccgaatgtcctgagaaagagaagctcccacag
gagtggaagaacaagacagccctgcagcgcctctgcatgctgagagccatgcggcccgac
cggatgacctatgctttgcgagattttgttgaagagaagttaggaagcaaatacgtggtg
ggaagagccctagattttgcaacctcatttgaagaatcgggaccagccactcctatgttt
ttcatcctgtctccaggggtggacccactgaaggatgtagaaagtcaaggaagaaaactt
ggatacaccttcaacaatcagaactttcacaacgtgtctttggggcaaggacaggaagtg
gtggctgaggctgcgctggacctcgctgccaagaaaggtcactgggttattttgcagaac
attcacctggtggccaagtggctcagcaccctggagaagaagctggaggagcacagtgag
aacagccacccagagttcagggtcttcatgagtgcagagccagcaccctcccctgagggc
cacatcatcccccagggcatcctggagaactccattaagatcaccaatgagccccccacg
ggcatgcatgccaacctgcacaaggccctggacaacttcactcaggacactctggagatg
tgttctcgggagacggagtttaagagcatcctctttgctctttgttacttccatgcggtg
gtggcagaaagacgaaaatttgggccccagggatggaatcgctcatacccctttaacact
ggagacctcactatctctgtgaatgtcctctacaacttcctggaggccaacgcaaaggtc
ccctatgatgatttgcgctacctgtttggagagatcatgtatggaggccatatcacagat
gactgggacagaagactctgcagaacctacctgggggaattcattcgaccagaaatgtta
gaaggagaactgtctttggccccagggttcccactcccaggcaacatggactacaatggt
tatcatcagtacatcgatgctgagctgcccccagaatccccctacctctatggcctccac
ccgaacgcagagattggcttcctgacccaaacctcagaaaagctcttccgcactgtgctg
gagctgcagcctcgggacagccaggccagagacggagcgggcgccacaagagaagaaaag
gtcaaggcacttctggaagaaatattggagcgggtgacagacgagtttaacatcccagaa
ctgatggccaaagtggaggagcgcaccccttacattgtagttgccttccaggagtgtggc
cggatgaatatcctcaccagagagattcagcgctcactgagggagctggagctcggctta
aagggggagctgactatgaccagccacatggagaacttacagaatgccctgtacttcgat
atggtgccagagtcctgggctagacgagcctacccttccacagcaggcctggcagcctgg
tttccagacctcctcaacagaatcaaggagctagaggcttggacgggtgactttacaatg
ccctccactgtgtggctgacaggcttcttcaacccccagtcgttcctgactgccatcatg
cagtccacggctcgcaagaatgagtggccactggaccagatggccctgcaatgtgacatg
acgaagaagaacagagaagagtttaggagtcctcctcgggaaggggcctacatccatggc
ctcttcatggaaggtgcctgctgggacacacaggctgggatcattacagaggcaaagctg
aaggatctgacaccccctatgcctgtgatgttcatcaaggccattcctgcagataagcag
gactgccgcagtgtctattcctgtcctgtgtacaagactagtcagcggggacccacctac
gtgtggactttcaacctgaagactaaggaaaacccatccaagtgggttctggctggagta
gccttgcttctccagatttag

KEGG   Homo sapiens (human): 196385Help
Entry
196385            CDS       T01001                                 

Gene name
DNAH10
Definition
(RefSeq) dynein axonemal heavy chain 10
  KO
K10408  dynein heavy chain, axonemal
Organism
hsa  Homo sapiens (human)
Pathway
hsa05016  Huntington disease
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09164 Neurodegenerative disease
   05016 Huntington disease
    196385 (DNAH10)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    196385 (DNAH10)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    Dyneins
     196385 (DNAH10)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: AAA_6 DHC_N1 DHC_N2 AAA_8 AAA_9 Dynein_C AAA_7 AAA_lid_11 MT Dynein_heavy AAA_5 Dynein_AAA_lid AAA_lid_1 AAA_22 AAA RsgA_GTPase AAA_18 Spo7_2_N Peptidase_S66C COMM_domain
Motif
Other DBs
NCBI-GeneID: 196385
NCBI-ProteinID: NP_997320
OMIM: 605884
HGNC: 2941
Ensembl: ENSG00000197653
Vega: OTTHUMG00000154477
Pharos: Q8IVF4(Tdark)
UniProt: Q8IVF4 B0I1S1
Position
12q24.31
AA seq 4471 aa AA seqDB search
MVPEEVEVEIDEIPVLSEEGEEEEETYSQKVESVDKVRAKRVSLRTESLGQPLNREDEEM
DKEISEKLPSKRTAKHIMEKMHLHMLCTPLPEEFLDQNVVFFLRNTKEAISEATDMKEAM
EIMPETLEYGIINANVLHFLKNIICQVFLPALSFNQHRTSTTVGVTSGEVSNSSEHESDL
PPMPGEAVEYHSIQLIRDEFLMNVQKFASNIQRTMQQLEGEIKLEMPIISVEGEVSDLAA
DPETVDILEQCVINWLNQISTAVEAQLKKTPQGKGPLAEIEFWRERNATLSALHEQTKLP
IVRKVLDVIKESDSMLVANLQPVFTELFKFHTEASDNVRFLSTVERYFKNITHGSGFHVV
LDTIPAMMSALRMVWIISRHYNKDERMIPLMERIAWEIAERVCRVVNLRTLFKENRASAQ
SKTLEARNTLRLWKKAYFDTRAKIEASGREDRWEFDRKRLFERTDYMATICQDLSDVLQI
LEEFYNIFGPELKAVTGDPKRIDDVLCRVDGLVTPMENLTFDPFSIKSSQFWKYVMDEFK
IEVLIDIINKIFVQNLENPPLYKNHPPVAGAIYWERSLFFRIKHTILRFQEVQEILDSDR
GQEVKQKYLEVGRTMKEYEDRKYEQWMEVTEQVLPALMKKSLLTKSSIATEEPSTLERGA
VFAINFSPALREIINETKYLEQLGFTVPELARNVALQEDKFLRYTAGIQRMLDHYHMLIG
TLNDAESVLLKDHSQELLRVFRSGYKRLNWNSLGIGDYITGCKQAIGKFESLVHQIHKNA
DDISSRLTLIEAINLFKYPAAKSEEELPGVKEFFEHIERERASDVDHMVRWYLAIGPLLT
KVEGLVVHTNTGKAPKLASYYKYWEKKIYEVLTKLILKNLQSFNSLILGNVPLFHTETIL
TAPEIILHPNTNEIDKMCFHCVRNCVEITKHFVRWMNGSCIECPPQKGEEEEVVIINFYN
DISLNPQIIEQAVMIPQNVHRILINLMKYLQKWKRYRPLWKLDKAIVMEKFAAKKPPCVA
YDEKLQFYSKIAYEVMRHPLIKDEHCIRLQLRHLANTVQENAKSWVISLGKLLNESAKEE
LYNLHEEMEHLAKNLRKIPNTLEDLKFVLATIAEIRSKSLVMELRYRDVQERYRTMAMYN
LFPPDAEKELVDKIESIWSNLFNDSVNVEHALGDIKRTFTELTRGEIMNYRVQIEEFAKR
FYSEGPGSVGDDLDKGVELLGVYERELARHEKSRQELANAEKLFDLPITMYPELLKVQKE
MSGLRMIYELYEGLKVAKEEWSQTLWINLNVQILQEGIEGFLRALRKLPRPVRGLSVTYY
LEAKMKAFKDSIPLLLDLKNEALRDRHWKELMEKTSVFFEMTETFTLENMFAMELHKHTD
VLNEIVTAAIKEVAIEKAVKEILDTWENMKFTVVKYCKGTQERGYILGSVDEIIQSLDDN
TFNLQSISGSRFVGPFLQTVHKWEKTLSLIGEVIEIWMLVQRKWMYLESIFIGGDIRSQL
PEEAKKFDNIDKVFKRIMGETLKDPVIKRCCEAPNRLSDLQNVSEGLEKCQKSLNDYLDS
KRNAFPRFFFISDDELLSILGSSDPLCVQEHMIKMYDNIASLRFNDGDSGEKLVSAMISA
EGEVMEFRKILRAEGRVEDWMTAVLNEMRRTNRLITKEAIFRYCEDRSRVDWMLLYQGMV
VLAASQVWWTWEVEDVFHKAQKGEKQAMKNYGRKMHRQIDELVTRITMPLSKNDRKKYNT
VLIIDVHARDIVDSFIRGSILEAREFDWESQLRFYWDREPDELNIRQCTGTFGYGYEYMG
LNGRLVITPLTDRIYLTLTQALSMYLGGAPAGPAGTGKTETTKDLAKALGLLCVVTNCGE
GMDYRAVGKIFSGLAQCGAWGCFDEFNRIDASVLSVISSQIQTIRNALIHQLTTFQFEGQ
EISLDSRMGIFITMNPGYAGRTELPESVKALFRPVVVIVPDLQQICEIMLFSEGFLEAKT
LAKKMTVLYKLAREQLSKQYHYDFGLRALKSVLVMAGELKRGSSDLREDVVLMRALRDMN
LPKFVFEDVPLFLGLISDLFPGLDCPRVRYPDFNDAVEQVLEENGYAVLPIQVDKVVQMF
ETMLTRHTTMVVGPTRGGKSVVINTLCQAQTKLGLTTKLYILNPKAVSVIELYGILDPTT
RDWTDGVLSNIFREINKPTDKKERKYILFDGDVDALWVENMNSVMDDNRLLTLANGERIR
LQAHCALLFEVGDLQYASPATVSRCGMVYVDPKNLKYRPYWKKWVNQIPNKVEQYNLNSL
FEKYVPYLMDVIVEGIVDGRQAEKLKTIVPQTDLNMVTQLAKMLDALLEGEIEDLDLLEC
YFLEALYCSLGASLLEDGRMKFDEYIKRLASLSTVDTEGVWANPGELPGQLPTLYDFHFD
NKRNQWVPWSKLVPEYIHAPERKFINILVHTVDTTRTTWILEQMVKIKQPVIFVGESGTS
KTATTQNFLKNLSEETNIVLMVNFSSRTTSMDIQRNLEANVEKRTKDTYGPPMGKRLLVF
MDDMNMPRVDEYGTQQPIALLKLLLEKGYLYDRGKELNCKSIRDLGFIAAMGKAGGGRNE
VDPRFISLFSVFNVPFPSEESLHLIYSSILKGHTSTFHESIVAVSGKLTFCTLALYKNIV
QDLPPTPSKFHYIFNLRDLSRVFNGLVLTNPERFQTVAQMVRVWRNECLRVFHDRLISET
DKQLVQQHIGSLVVEHFKDDVEVVMRDPILFGDFQMALHEGEPRIYEDIQDYEAAKALFQ
EILEEYNESNTKMNLVLFDDALEHLTRVHRIIRMDRGHALLVGVGGSGKQSLSRLAAFTA
SCEVFEILLSRGYSENSFREDLKSLYLKLGIENKAMIFLFTDAHVAEEGFLELINNMLTS
GIVPALFSEEEKESILSQIGQEALKQGMGPAKESVWQYFVNKSANNLHIVLGMSPVGDTL
RTWCRNFPGMVNNTGIDWFMPWPPQALHAVAKSFLGYNPMIPAENIENVVKHVVLVHQSV
DHYSQQFLQKLRRSNYVTPKNYLDFINTYSKLLDEKTQCNIAQCKRLDGGLDKLKEATIQ
LDELNQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKLAEEKAMEIEEQNKVIAME
KAEAETTLAEVMPILEAAKLELQKLDKSDVTEIRSFAKPPKQVQTVCECILIMKGYKELN
WKTAKGVMSDPNFLRSLMEIDFDSITQSQVKNIKGLLKTLNTTTEEMEAVSKAGLGMLKF
VEAVMGYCDVFREIKPKREKVARLERNFYLTKRELERIQNELAAIQKELETLGAKYEAAI
LEKQKLQEEAEIMERRLIAADKLISGLGSENIRWLNDLDELMHRRVKLLGDCLLCAAFLS
YEGAFTWEFRDEMVNRIWQNDILEREIPLSQPFRLESLLTDDVEISRWGSQGLPPDELSV
QNGILTTRASRFPLCIDPQQQALNWIKRKEEKNNLRVASFNDPDFLKQLEMSIKYGTPFL
FRDVDEYIDPVIDNVLEKNIKVSQGRQFIILGDKEVDYDSNFRLYLNTKLANPRYSPSVF
GKAMVINYTVTLKGLEDQLLSVLVAYERRELEEQREHLIQETSENKNLLKDLEDSLLREL
ATSTGNMLDNVDLVHTLEETKSKATEVSEKLKLAEKTALDIDRLRDGYRPAARRGAILFF
VLSEMALVNSMYQYSLIAFLEVFRLSLKKSLPDSILMKRLRNIMDTLTFSIYNHGCTGLF
ERHKLLFSFNMTIKIEQAEGRVPQEELDFFLKGNISLEKSKRKKPCAWLSDQGWEDIILL
SEMFSDNFGQLPDDVENNQTVWQEWYDLDSLEQFPVPLGYDNNITPFQKLLILRCFRVDR
VYRAVTDYVTVTMGEKYVQPPMISFEAIFEQSTPHSPIVFILSPGSDPATDLMKLAERSG
FGGNRLKFLAMGQGQEKVALQLLETAVARGQWLMLQNCHLLVKWLKDLEKSLERITKPHP
DFRLWLTTDPTKGFPIGILQKSLKVVTEPPNGLKLNMRATYFKISHEMLDQCPHPAFKPL
VYVLAFFHAVVQERRKFGKIGWNVYYDFNESDFQVCMEILNTYLTKAFQQRDPRIPWGSL
KYLIGEVMYGGRAIDSFDRRILTIYMDEYLGDFIFDTFQPFHFFRNKEVDYKIPVGDEKE
KFVEAIEALPLANTPEVFGLHPNAEIGYYTQAARDMWAHLLELQPQTGESSSGISRDDYI
GQVAKEIENKMPKVFDLDQVRKRLGTGLSPTSVVLLQELERFNKLVVRMTKSLAELQRAL
AGEVGMSNELDDVARSLFIGHIPNIWRRLAPDTLKSLGNWMVYFLRRFSQYMLWVTESEP
SVMWLSGLHIPESYLTALVQATCRKNGWPLDRSTLFTQVTKFQDADEVNERAGQGCFVSG
LYLEGADWDIEKGCLIKSKPKVLVVDLPILKIIPIEAHRLKLQNTFRTPVYTTSMRRNAM
GVGLVFEADLFTTRHISHWVLQGVCLTLNSD
NT seq 13416 nt NT seq  +upstreamnt  +downstreamnt
atggtgccggaggaggtggaggtggagattgatgagatacctgtcctgtctgaagaggga
gaagaggaagaagagacttattctcaaaaagtggagtccgtggataaagtgcgagctaag
cgtgtgtcactgagaaccgaatctctaggccaacctctaaacagagaggatgaagaaatg
gacaaagagatttcagaaaaactcccttccaaaagaactgcgaagcacatcatggaaaag
atgcatctccacatgctctgtacccctcttcccgaggagttcctggaccaaaacgtggtg
tttttcctcagaaataccaaagaggcaatctctgaagctaccgacatgaaggaagctatg
gaaattatgccagaaacactggagtatggaattataaacgctaatgtgctccattttctg
aagaatattatatgtcaggtttttttgccagcattgtccttcaatcagcacaggacgagt
acaaccgtgggagtcacatctggagaagtctctaattcctctgagcatgaatcagacctg
ccgcccatgcctggggaggcagtagaatatcacagtattcaattaatacgggatgaattt
ttaatgaacgtgcagaaatttgcaagtaatattcaaagaaccatgcagcaacttgaaggt
gagatcaagttagaaatgccaatcatcagtgtggagggagaggtgtctgacctggcagct
gacccggaaaccgttgacatcttggagcagtgtgtgataaactggctgaatcagatatcc
acagcggttgaggcccaactgaagaagacacctcagggtaaaggccctctggctgaaatt
gaattctggagggaaagaaatgcaaccttaagtgcgctgcatgaacaaacaaagcttcca
atagtcagaaaagtcttggatgtgatcaaggaatccgactccatgcttgtggctaatctg
cagccagtgttcaccgagttattcaagttccacacggaggcctcagacaatgtgcgcttt
ctctccaccgtggagcgttatttcaagaacataacgcacgggtctggcttccacgtggtc
ctggacaccatccccgccatgatgagtgccctgcggatggtgtggatcatctcccgacac
tacaacaaagacgagaggatgattccgctcatggagcgcatcgcctgggaaatcgctgag
agagtctgccgagtggtcaacctgcggactttgttcaaagaaaatcgagcgagtgcccaa
agcaaaaccttggaagccaggaacaccctcaggctgtggaaaaaggcctattttgacacc
cgggccaagatagaggcttcggggagggaagatcggtgggagtttgaccggaagcggctg
ttcgagaggacggattatatggccaccatctgccaggacctctccgacgttctgcagatt
ttggaggaattttataacatatttggtccagaactaaaggcagtgacgggggaccccaag
cgcattgatgatgtcctatgcagagtggacggcctagtcacccccatggaaaacctgacc
tttgaccccttcagcatcaagtcctcccagttctggaaatatgtgatggatgaattcaag
attgaagttctgattgacatcattaataaaatctttgtccagaaccttgaaaatccacca
ctgtataagaatcaccctccagtagcaggtgcaatatactgggaacgatctctgttcttt
cggattaagcataccatcctccgatttcaagaggtacaagagatactggacagtgatcga
ggacaggaggtcaaacaaaaatatttggaagtaggtaggacaatgaaggagtatgaagac
agaaagtatgagcagtggatggaggtgacggagcaggtgctgccagctctcatgaagaag
agccttttgaccaagtcttccatcgccacagaggagccttcgactttagaaaggggagct
gtttttgcaatcaacttttcaccggctctcagagagattattaatgaaacaaagtactta
gagcagctggggttcactgtccctgaattagcaagaaatgttgctctccaggaagacaaa
ttccttaggtacacagctgggatacagcgcatgttggatcattatcacatgctcatagga
acgttaaacgatgcggagtctgtgcttctcaaagatcattcccaggaactgctccgagtg
tttaggtcgggatataagaggttgaactggaactcactaggtatcggtgactatataact
ggttgcaaacaggccattgggaaatttgagtctctcgtccaccagattcataagaatgca
gatgacatttcttccaggctgacattaatagaggccataaatctctttaaatatccagcc
gctaaaagtgaggaagaactcccaggcgtgaaggaattttttgaacacattgagcgagaa
agggccagcgacgtggaccacatggtccggtggtatcttgccattggaccactgctgacc
aaagttgagggcctggtcgtccacaccaacacaggcaaggcccccaagctggcctcctac
tacaaatactgggaaaagaaaatttatgaggtcctgacaaagctcatcctgaagaacttg
cagtcttttaattctttgatccttggaaatgtccctctgttccacactgaaaccattctg
acggcacctgagatcatccttcatcccaacacaaatgagatcgacaagatgtgcttccat
tgtgtccggaattgcgtggagatcaccaagcattttgttcgttggatgaatggcagctgc
atagaatgcccacctcagaagggggaggaagaggaagttgttataataaacttttacaat
gatatctctctgaaccctcagataattgaacaagctgttatgatcccccaaaatgtccac
aggattctgatcaatcttatgaagtatctacaaaaatggaagcggtatcgacctctctgg
aaattggacaaagctattgtgatggagaaatttgctgccaagaaacctccttgtgtagca
tatgatgaaaagttgcagttctattccaagatagcttatgaggttatgcgccaccctcta
attaaggatgagcattgcatcagacttcagctcaggcatctggcaaacacagtgcaggaa
aatgccaagtcctgggtgatttcgcttggaaaacttctcaatgagtcagcaaaagaggag
ctctataatctccatgaagagatggagcacctggccaaaaaccttaggaagatccccaat
acccttgaagatctcaagtttgtccttgcaacaattgcagaaattagaagtaaatctcta
gtcatggaactcagatatagggacgtccaggagcgataccgtaccatggcaatgtataac
ctctttcctcctgatgcagagaaagaactggttgataagattgagagcatatggtccaat
ctgtttaatgattcagtgaatgtggagcatgctcttggggacataaagagaactttcaca
gagcttactcgaggcgaaataatgaactacagagttcagatagaggagtttgcaaagcgt
ttttacagtgaaggccctggttctgttggtgatgatcttgataaaggagtagagctttta
ggtgtttatgaaagagagctggcaagacatgaaaagagccgtcaggaactggctaacgct
gagaaacttttcgatcttcctattacaatgtacccagagctgctgaaagtgcagaaggaa
atgagtgggctgaggatgatttacgagctctatgaaggactaaaggttgcaaaagaagaa
tggtctcagaccctttggatcaacctgaatgtgcagattctccaggaaggaattgaaggt
tttctcagggctctcagaaagctacctcggccagtccgtggcttatcagtgacctactac
ttggaagcaaaaatgaaggcattcaaagactcgattcctttacttcttgacttgaaaaac
gaggcactaagagacaggcattggaaagaacttatggaaaaaacgtctgtcttttttgaa
atgaccgaaacgttcaccttggaaaatatgtttgctatggaactgcacaaacacacagat
gttctcaatgagattgtcacagcagcaatcaaggaggttgccattgagaaggctgtgaag
gaaatcctagacacgtgggaaaatatgaaattcactgtagtcaagtattgcaaaggcaca
caggagcgaggctacatcctgggttctgttgacgaaattattcagtctcttgatgacaac
actttcaacctgcagagcatctcaggaagcagatttgtggggccttttctgcaaactgtt
cacaaatgggaaaaaacgctttctctaataggggaagtcattgagatttggatgttggtt
cagagaaaatggatgtatcttgaaagtatttttattggtggagatataagatcacaactt
ccggaagaggcaaaaaagtttgacaacatcgataaagtatttaaaaggatcatgggtgag
accttaaaagaccccgtgatcaagaggtgctgtgaagccccaaaccgcctcagtgaccta
cagaacgtcagcgagggcctggagaaatgccagaaaagcctcaacgactacttagattcg
aagagaaatgctttcccaaggttcttcttcatttctgacgatgagttgcttagcattctg
gggagcagcgacccactctgcgtccaggagcacatgatcaagatgtacgacaacatagca
tcactgaggtttaatgacggcgatagtggagaaaaactggtgtccgcgatgatttcagca
gaaggagaagtcatggagtttcggaagatcttgcgggctgaagggcgcgtggaggactgg
atgacggcagttttgaatgagatgagaagaactaatagactaattaccaaagaggctatt
tttagatactgtgaagacagaagcagagtcgactggatgctcctgtaccagggcatggtg
gtgctggccgctagccaggtgtggtggacctgggaggtggaagacgtcttccacaaagcg
caaaaaggggagaagcaggccatgaagaactatggcaggaaaatgcaccggcagatcgat
gagttggtaacgcgcatcaccatgccgctaagcaaaaacgacaggaaaaaatacaacact
gttctcatcattgatgtgcatgccagagacatagttgattctttcataagaggcagtatc
ctggaggcccgagagtttgactgggaaagtcagttgcggttttattgggaccgggagccg
gatgagctgaacatccgccagtgcacgggaacctttggctacggctacgagtacatgggc
ctgaacggcaggctggtcatcacgcccctcaccgatcggatttacctgacgctcacccag
gcgctgtccatgtatctaggtggggcccccgccggcccagcaggaaccggcaaaaccgag
accaccaaggacctggcgaaagccttgggcttgctctgtgttgtcaccaactgtggcgaa
ggcatggattacagggccgtggggaagattttctctggcctggcacagtgcggggcttgg
ggctgctttgatgagtttaatcgaatcgatgcttctgtgctctccgtgatctcctcccag
atccagacgatccgaaatgctctgatccatcagttaaccacgttccagtttgaagggcag
gagatttccctggactcccgcatgggcatcttcatcaccatgaaccccggctacgcaggc
cgcacggagctgcccgagtcggtgaaggcgctgttcaggcctgtggtcgtgatcgtgccc
gacctgcagcagatctgtgagatcatgctcttctctgagggcttcctggaggccaagact
ctggcgaaaaagatgacggttctgtataagctggcccgggagcagctgtccaagcagtat
cactatgattttggactcagagccctgaaatcggtgctggtcatggctggtgagctgaag
agaggctcctctgaccttagggaggacgtggtgctgatgagggccttgcgagacatgaac
ttgcccaaatttgtgtttgaagatgttcctcttttccttggtttgatttcggatctgttt
cctgggctggactgccctcgcgtccgctaccctgacttcaacgatgcggtagagcaggtc
ctggaggagaacggctacgcggtcctacccatccaggtggataaagtggttcaaatgttc
gagaccatgttaacccgccacacgacgatggtggtggggcccaccagagggggcaagtcc
gtcgtcattaacactctgtgtcaggcccagaccaagcttgggctgacgacaaagttgtac
atcctgaaccccaaagccgtgagtgtcatagaactctacggcatcctggacccaaccacc
cgagactggacagatggggtgttgtcaaacatcttcagggaaatcaacaagccaacagac
aagaaggagcgaaagtatattttatttgatggtgatgtggatgctctatgggtggaaaac
atgaattctgtgatggatgacaacaggttgttgacattggccaacggggaacgcatccgg
ctccaagcacactgtgccctgctctttgaggttggagatttacagtatgcctcccctgca
actgtctctcgatgtggaatggtttatgtggatcctaaaaacttgaaatatcgaccatac
tggaaaaaatgggttaatcaaataccaaacaaggtggagcaatacaatttgaatagtctc
tttgagaagtatgtgccctatctcatggatgtgatagtggaaggaattgtggatggaaga
caagcagaaaagctgaagacaatagttcctcagacagacctcaatatggtaacccagtta
gccaagatgttggatgcgttgctagaaggagaaatagaagaccttgacctgctggagtgc
tacttcctggaggctttgtactgctctctgggagcctccctgcttgaggatggaaggatg
aaatttgacgaatatatcaaacgccttgcttctttgtctactgttgacacagaaggagtt
tgggccaaccctggggaactgccaggtcaacttccaaccttgtatgactttcattttgat
aacaaacggaatcaatgggtcccatggagtaaattagttccagagtatattcatgccccc
gagaggaaattcatcaacatcctggttcacacagtggataccactcggactacctggata
ttggaacaaatggttaaaattaagcaacctgttatttttgttggtgaatctggcacttct
aagacagccactacccagaatttcctcaaaaatctgagtgaagaaactaacattgtgtta
atggtcaacttctcctcccgcaccacgtccatggatatccaaagaaatttagaagcaaat
gtggaaaagcgaaccaaagatacttacggcccacccatgggaaaacgcctgctggtgttc
atggatgacatgaatatgccaagggtggatgaatatggcacgcagcagcccattgccttg
ctgaagctgctgttggaaaaaggctacttatatgaccgtgggaaggagctgaactgtaaa
agcattcgagaccttggctttattgctgcaatgggaaaggctggaggaggccgcaatgaa
gttgacccaagatttatttcgctattcagtgtcttcaatgtgccatttccttcagaggag
tctctgcatttaatttattcctccatcctgaaaggccacacctcgacgtttcatgagagc
attgtggctgtgagtggcaagctgacattctgcacgctagcactttacaaaaatattgtg
caagacctacctcccactccgtcaaagttccattacatcttcaaccttcgagatctctca
cgggtttttaatggtcttgtcctcactaacccggagcgattccagacggtggcccagatg
gtgagagtctggaggaatgagtgtctgagagtcttccacgaccggctgatcagtgaaaca
gacaagcagctggtacaacagcacataggcagcttggttgtggaacattttaaagatgac
gtggaggtggtgatgagggatcccatattgtttggagacttccagatggctctgcacgaa
ggagaaccacgcatttatgaagacatccaggactacgaggcggccaaggctctgttccag
gaaattcttgaagagtataatgaaagcaacaccaaaatgaacttggttctcttcgacgat
gctctggagcatttaacccgggtgcaccgtatcatccgcatggaccgcggccacgccctg
ctggtcggggtagggggctcagggaagcagtctctttcgaggctggctgccttcacagcc
agctgtgaggtgtttgagatcctgctgagccgaggctactcggagaacagtttccgggaa
gacctgaagagcctctatttgaaacttgggattgagaacaaagcgatgatctttctgttc
acggatgcccatgtggctgaggagggcttcctggagctcatcaacaacatgctgacctca
ggaattgtacctgcgcttttttctgaagaggagaaagagtctatcctgagtcagattgga
caggaagctctgaagcaaggcatggggccggccaaggagtctgtgtggcagtacttcgtg
aacaaaagtgcaaataacctgcacattgtcctgggcatgtcgccagtgggggacaccctg
aggacctggtgcagaaacttcccaggtatggtaaataacactggtattgactggttcatg
ccctggcctccccaagccctccatgcggtcgcaaagtcctttctagggtataatccaatg
atcccggcagaaaatatagaaaatgtggtgaagcatgttgtcttggttcaccaatccgtg
gaccactacagccaacagtttctacagaaattgaggcgcagcaactatgtcactcccaag
aactaccttgattttattaacacctattcaaaattgctggatgagaaaactcagtgtaat
atagctcagtgcaagcgtctggatgggggactggacaagctgaaggaggccaccatccag
ctggacgagctgaaccagaagctggccgagcagaagatcgtgctggcggagaagtccgcc
gcctgcgaggccttgctggaggagatcgccgtcaacaccgctgtagccgaggagaagaag
aaactggcagaggaaaaggccatggagatagaggagcagaacaaagtcattgccatggag
aaggccgaggccgagacgaccctggcagaggtcatgcccatcctggaggccgccaagctg
gaactgcagaagctggacaagtcggacgtgactgagattaggtcgtttgctaagcccccg
aagcaggtgcagacggtctgcgaatgcatcctcatcatgaaagggtacaaagagctgaac
tggaaaacagccaagggcgtgatgtccgacccgaatttcctgcggtctctgatggagatt
gattttgattcgattacccagagccaagtgaaaaacatcaaaggcctcttgaagactctt
aataccacaactgaagaaatggaagctgtcagcaaagccgggctggggatgctgaaattt
gttgaagctgtaatgggctactgtgatgttttcagagaaatcaagcccaaaagagagaag
gtggccaggctggagcggaatttttacctcactaaacgggaactggaaaggatccagaat
gagttggcagcaattcagaaagagctggaaacattgggtgccaaatatgaggccgccata
ctggaaaagcagaagctgcaggaagaagccgagatcatggagaggcggctgattgccgca
gacaaactcatctcgggtctggggtcagaaaacatcaggtggctgaacgacctggatgag
ctgatgcaccggcgcgtgaagctgctgggggactgcctgctctgcgcggctttcctcagc
tacgagggagccttcacctgggagttccgtgacgagatggtcaatcggatttggcaaaat
gacatcctggagcgggagatccccctgagccagcctttccggctggaaagcctgctcacg
gatgatgttgagatcagcagatggggatcccagggccttccccccgatgagctctccgtt
cagaatggcatcctcaccacccgggccagccgcttccctctgtgtatcgacccccagcag
caggccctcaactggatcaagagaaaagaggagaagaacaatctgcgggtcgcttccttt
aatgaccctgacttcctcaagcagctagagatgtccataaagtacgggacccctttcctg
ttccgcgatgttgatgaatacatcgatcctgtgattgacaacgtcttagaaaaaaatata
aaagtctcccaaggacggcagtttattatcctgggagacaaggaagtggactatgattca
aatttcagactgtacctgaacaccaagctggccaatcccagatattccccatccgtgttt
gggaaagctatggtgatcaattacactgtcacgctgaagggcctggaggaccagctgctg
agcgtgctggtggcttacgagaggcgggagctggaggagcagcgggagcacctcatccag
gagaccagcgagaacaagaacctgctcaaggacctggaagattccctccttcgggagctg
gccacgtccacggggaacatgctggacaatgtggacctggtgcacaccctggaggagacc
aaatccaaggcaacagaggtctcagagaaactcaagctggcggagaagacagccttggac
atcgacaggctgcgggatggctaccggccagcagccaggaggggggccatcctgttcttc
gtcctgtctgagatggccctggtgaactccatgtaccagtactccctgattgccttctta
gaggtcttcaggctgtcactgaagaagtcgctgcctgattccatcctcatgaaacgcctg
aggaacatcatggacacgctgaccttcagcatctataaccacggctgcacagggctgttt
gagaggcacaagctactcttttcttttaatatgaccatcaagatagaacaagcagaaggg
agagtccctcaagaagaactagatttctttttaaaaggaaacatttccctggagaaaagc
aaaagaaaaaagccctgcgcttggttgtctgaccaaggatgggaagatatcattctttta
tcagaaatgttttcagacaactttgggcaacttcctgatgatgttgagaataatcagact
gtctggcaggagtggtatgacctggattcactggagcagtttcccgtccccttgggttac
gataacaacatcacccctttccagaagttgcttattttgcgctgtttccgtgtggatcgg
gtctatcgggccgtgactgactatgtgactgtaacaatgggagagaagtatgtgcagccc
ccaatgatcagctttgaagctatttttgagcagagcactccacattcgcccattgtgttt
atcctgagtcctggctccgaccctgccactgatcttatgaaattagcagagcgaagtggt
tttggaggaaatcgcctcaaattccttgcaatgggtcaaggtcaagaaaaggtggccctg
cagctgctggagacggcggtggctcgggggcagtggctgatgctgcagaactgccacctc
ctggtcaagtggctgaaagatctggagaagtccctggagaggatcaccaagccccaccca
gacttccgcctgtggctcaccacggaccccaccaagggcttccccattgggattctgcag
aagtccctaaaggttgtcaccgagccacccaatgggctgaaactcaacatgagggcaact
tacttcaagatctctcacgaaatgctggaccagtgcccgcaccctgccttcaagccgctg
gtctacgtgctggcgttctttcatgctgtggtgcaggagagaaggaagtttgggaagatt
ggctggaacgtgtactatgacttcaatgagtctgacttccaggtctgcatggaaattctg
aacacgtacttaacgaaagccttccagcaacgggacccaaggatcccgtggggcagcctc
aagtacctaattggagaggtcatgtatggaggacgggccatcgacagctttgatcgccgc
atcctgaccatctacatggatgagtacctgggggacttcatttttgatactttccagcca
ttccacttcttccggaacaaggaagtggactacaaaatccctgttggtgatgaaaaggag
aaatttgttgaagccatcgaggccctcccgcttgccaacacgccagaagtgtttggtctc
caccccaacgctgagattggctattacacgcaggcggctcgagacatgtgggctcacctg
ctggagctgcagcctcagacaggggaatccagcagtggtatcagccgcgatgattatatt
ggccaagtggccaaagaaatagaaaacaagatgcccaaagtctttgacttggaccaggtg
aggaagcgcctcggaacaggactctcccccacttcggtggtgctcctgcaggaactggaa
cgcttcaacaagcttgtggtccggatgacgaagtctctggctgaacttcaaagggccttg
gctggagaagttggaatgagcaatgagttagatgatgtggccaggtctctttttatcggg
catatccctaatatctggagaaggcttgctcctgacaccttaaagtcccttggaaactgg
atggtctacttcctgcggcggttcagccagtacatgttgtgggtgaccgagagcgagccc
agcgtgatgtggctctcggggctgcacatccctgagtcctacctcacggcgctggtgcag
gccacctgccggaagaacggctggccactggaccgctccaccttgttcacacaagtgacc
aagttccaggatgcagatgaagtgaatgagcgggcgggacaaggatgctttgtctcagga
ctgtacctggaaggtgctgactgggatatagaaaaaggatgtcttatcaagagcaaaccc
aaggtgctggttgtggacctgccgatcctgaagatcatccccattgaagcccatcgcctc
aagctgcagaatactttccggacccccgtctacaccacctccatgagaaggaacgccatg
ggagtcggcttggtttttgaagctgatctctttaccacgaggcacatttctcactgggtg
ctgcaaggagtatgcctcaccctgaattctgattaa

KEGG   Homo sapiens (human): 201625Help
Entry
201625            CDS       T01001                                 

Gene name
DNAH12, DHC3, DLP12, DLP3, DNAH12L, DNAH7L, DNAHC12, DNAHC3, DNHD2, HDHC3, HL-19, HL19
Definition
(RefSeq) dynein axonemal heavy chain 12
  KO
K10408  dynein heavy chain, axonemal
Organism
hsa  Homo sapiens (human)
Pathway
hsa05016  Huntington disease
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09164 Neurodegenerative disease
   05016 Huntington disease
    201625 (DNAH12)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    201625 (DNAH12)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    Dyneins
     201625 (DNAH12)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Sod_Fe_N
Motif
Other DBs
NCBI-GeneID: 201625
NCBI-ProteinID: NP_940966
OMIM: 603340
HGNC: 2943
Ensembl: ENSG00000174844
Vega: OTTHUMG00000158598
Pharos: Q6ZR08(Tdark)
UniProt: Q6ZR08
Position
3p14.3
AA seq 457 aa AA seqDB search
MSDANKAAIAAEKEALNLKLPPIVHLPENIGVDTPTQSKLLKYRRSKEQQQKINQLVIDG
AKRNLDRTLGKRTPLLPPPDYPQTMTSEMKKKGFNYIYMKQCVESSPLVPIQQEWLDHML
RLIPESLKEGKEREELLESLINEVSSDFENSMKRYLVQSVLVKPPVKSLEDEGGPLPESP
VGLDYSNPWHSSYVQARNQIFSNLHIIHPTMKMLLDLGYTTFADTVLLDFTGIRAKGPID
CESLKTDLSIQTRNAEEKIMNTWYPKVINLFTKKEALEGVKPEKLDAFYSCVSTLMSNQL
KDLLRRTVEGFVKLFDPKDQQRLPIFKIELTFDDDKMEFYPTFQDLEDNVLSLVERIAEA
LQNVQTIPSWLSGTSTPVNLDTELPEHVLHWAVDTLKAAVHRNLEGARKHYETYVEKYNW
LLDGTAVENIETFQTEDHTFDEYTEELDCWVVWEVYF
NT seq 1374 nt NT seq  +upstreamnt  +downstreamnt
atgtcagatgcaaacaaagctgccattgcagcagaaaaggaagctctgaacttgaagtta
ccccccattgtccatctcccagaaaacataggcgttgatacaccaacacaaagtaagctg
ctaaaatacagaagatccaaggagcagcagcagaaaattaatcagttagtaattgatgga
gccaaaagaaatttagacagaacactgggtaaaagaacacctctattaccaccacctgat
tatcctcaaactatgaccagtgaaatgaaaaaaaaaggattcaactatatttatatgaag
caatgtgtagaaagtagtcctttagtacctattcagcaggaatggctggatcacatgtta
aggctgatacctgagtctttaaaggaagggaaagaaagagaagaacttcttgaaagtctc
ataaatgaggtgtcaagtgactttgaaaacagcatgaagagatatttggtgcagagcgtt
cttgtgaaaccaccagttaaatcgcttgaagatgaaggaggtcctttacctgaatctcct
gtaggcctagattattctaatccttggcattctagctatgtgcaggcaagaaatcaaata
ttctctaatttgcacattattcatccaactatgaaaatgttactggaccttggttataca
acatttgctgatacagttttgttggacttcacaggaattagagctaaaggtccaattgac
tgtgaatcactgaaaactgatctatcaatacaaactagaaacgcagaagagaagataatg
aatacatggtatccaaaggttataaatctctttaccaagaaggaggcactagaaggtgtt
aaacctgaaaaattggatgcattttatagctgtgtttccacacttatgtcaaatcagcta
aaggatctattaaggagaactgtagaaggatttgtaaaactctttgacccaaaagatcaa
caaaggctgccaatatttaagatagaattgacatttgatgacgacaaaatggaattttat
cctacctttcaagatttggaagataatgtcttgagtttggtggaacgaatagccgaagct
ctgcagaatgtccaaacaatcccctcttggctatcaggaacttcaacaccagtaaatctt
gacacagaacttcctgaacacgtgttacactgggctgttgatacactgaaggcagcagta
catcggaacttagaaggtgcaagaaagcattatgagacatatgttgaaaaatataattgg
ctccttgatgggactgcagttgagaatatagagacttttcagacagaagatcatactttt
gatgaatatacagaggagctggattgctgggtggtatgggaagtgtatttttaa

KEGG   Homo sapiens (human): 25981Help
Entry
25981             CDS       T01001                                 

Gene name
DNAH1, CILD37, DNAHC1, HDHC7, HL-11, HL11, HSRF-1, SPGF18, XLHSRF-1
Definition
(RefSeq) dynein axonemal heavy chain 1
  KO
K10408  dynein heavy chain, axonemal
Organism
hsa  Homo sapiens (human)
Pathway
hsa05016  Huntington disease
Disease
H00564  Primary ciliary dyskinesia
H01282  Spermatogenic failure
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09164 Neurodegenerative disease
   05016 Huntington disease
    25981 (DNAH1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    25981 (DNAH1)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    Dyneins
     25981 (DNAH1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: AAA_6 DHC_N2 Dynein_C AAA_8 AAA_9 AAA_7 AAA_lid_11 MT Dynein_heavy Dynein_AAA_lid AAA_lid_1 AAA_5 AAA_18 AAA_22 AAA_16 T2SSE ABC_tran AAA_33 Mg_chelatase Seryl_tRNA_N AAA_29 zf-C4H2
Motif
Other DBs
NCBI-GeneID: 25981
NCBI-ProteinID: NP_056327
OMIM: 603332
HGNC: 2940
Ensembl: ENSG00000114841
Vega: OTTHUMG00000158378
Pharos: Q9P2D7(Tbio)
UniProt: Q9P2D7 A0A140VJI6
Position
3p21.1
AA seq 4265 aa AA seqDB search
MEQPNSKGYSLGRTPQGPECSSAPAVQVGTHRGLEYNPGKILPGSDYGLGNPPALDPKLP
HLPLPPAPPTLSDLGQPRKSPLTGTDKKYPLMKQRGFYSDILSPGTLDQLGEVCRGPRMS
QNLLRQADLDKFTPRVGSFEVPEDFQERMEQQCIGSTTRLLAQTDFPLQAYEPKMQVPFQ
VLPGQHPRKIEIERRKQQYLSLDIEQLLFSQGIDSNKLMPRHLDHQHPQTIEQGHDPIFP
IYLPLKVFDNEDFDCRTPREWINMGLEPGSLDRKPVPGKALLPTDDFLGHEDPKSQKLKY
KWCEVGVLDYDEEKKLYLVHKTDEKGLVRDEMGRPILNAGVTTEGRPPLQVCQYWVPRIQ
LLFCAEDPCMFAQRVVQANALRKNTEALLLYNLYVDCMPSDGQHVISEQSLSKIKQWALS
TPRMRKGPSVLEHLSSLAREVSLDYERSMNKINFDHVVSSKPETFSYVTLPKKEEEQVPE
RGLVSVPKYHFWEQKEDFTFVSLLTRPEVITALSKVRAECNKVTAMSLFHSSLSKYSHLE
EFEQIQSQTFSQVQMFLKDSWISSLKVAMRSSLRDMSKGWYNLYETNWEVYLMSKLRKLM
ELVKYMLQDTLRFLVQDSLASFSQFISDTCCSVLNCTDDMVWGDDLINSPYRPRKNPLFI
MDLVLDSSGVHYSTPLEQFEASLLNLFDKGILATHAVPQLEKLVMEDIFISGDPLLESVG
LHEPLVEELRATIASAVSKAMIPLQAYAKEYRKYLELNNNDIASFLKTYQTQGLLAQEVR
EVVLTHLREKEILDSSLPSSIIIGPFYINTDNVKQSLSKKRKALATSVLDILAKNLHKEV
DSICEEFRSISRKIYEKPNSIEELAELREWMKGIPERLVGLEERIVKVMDDYQVMDEFLY
NLSSDDFNDKWIASNWPSKILGQIELVQQQHVEDEEKFRKIQIMDQNNFQEKLEGLQLVV
AGFSIHVEISRAHEIANEVRRVKKQLKDCQQLAMLYNNRERIFSLPITNYDKLSRMVKEF
QPYLDLWTTASDWLRWSESWMNDPLSAIDAEQLEKNVVEAFKTMHKCVKQFKDMPACQEV
ALDIRARIEEFKPYIPLIQGLRNPGMRIRHWETLSNQININVRPKANLTFARCLEMNLQD
HIESISKVAEVAGKEYAIEQALDKMEKEWSTILFNVLPYKATDTYILKSPDEASQLLDDH
IVMTQNMSFSPYKKPFEQRINSWENKLKLTQEVLEEWLNCQRSWLYLEPIFSSEDINQQL
PVESKRYQTMERIWKKIMKNAYENREVINVCSDLRMLDSLRDCNKILDLVQKGLSEYLET
KRSAFPRFYFLSDDELLEILSQTKDPTAVQPHLRKCFENIARLLFQEDLEITHMYSAEGE
EVQLCFSIYPSSNVEDWLREVERSMKASVHDIIEKAIRAYPTMPRTQWVLNWPGQVTIAG
CQTYWTMEVAEALEAGNLRSQLFPQLCQQLSDLVALVRGKLSRMQRAVLSALIVIEVHAK
DVVSKLIQENVVSVNDFQWISQLRYYWTNNDLYIRAVNAEFIYGYEYLGNSGRLVITPLT
DRCYLTLTGALHLKFGGAPAGPAGTGKTETTKDLGKALAIQTVVFNCSDQLDFMAMGKFF
KGLASAGAWACFDEFNRIDIEVLSVVAQQITTIQKAQQQRVERFMFEGVEIPLVPSCAVF
ITMNPGYAGRTELPDNLKALFRPVAMMVPDYAMITEISLYSFGFNEASVLAKKITTTFKL
SSEQLSSQDHYDFGMRAVKTVISAAGNLKRENPSMNEELICLRAIRDVNVPKFLQEDLKL
FSGIVSDLFPTIKEEDTDYGILDEAIREACRNSNLKDVEGFLTKCIQLYETTVVRHGLML
VGPTGSGKSTCYRVLAAAMTSLKGQPSISGGMYEAVNYYVLNPKSITMGQLYGEFDLLTH
EWTDGIFSSFIRAGAITSDTNKKWYMFDGPVDAIWIENMNTVLDDNKKLCLSSGEIIKLT
EAMTMMFEVQDLAVASPATVSRCGMVYLEPSILGLMPFIECWLRKLPPLLKPYEEHFKAL
FVSFLEESISFVRSSVKEVIASTNCNLTMSLLKLLDCFFKPFLPREGLKKIPSEKLSRIV
ELIEPWFIFSLIWSVGATGDSSGRTSFSHWLRLKMENEQLTLLFPEEGLVFDYRLEDAGI
SGTNDSEDEEEEYKQVAWVKWMDSSAPFTMVPDTNYCNIIVPTMDTVQMSHLLDMLLTNK
KPVLCIGPTGTGKTLTISDKLLKNLALDYISHFLTFSARTSANQTQDFIDSKLDKRRKGV
FGPPLGRNFIFFIDDLNMPALETYGAQPPIELLRQWMDHGGWYDRKIIGAFKNLVDINFV
CAMGPPGGGRNTVTPRLMRHFNYLSFAEMDEVSKKRIFSTILGNWLDGLLGEKSYRERVP
GAPHIAHFTEPLVEATIMVYATITSQLLPTPAKSHYTFNLRDLSKVFQGMLMADPAKVED
QVQLLRLWYHENCRVFRDRLVNEEDRSWFDQLLKRCMEQWEVTFNKVCPFQPILYGDFMS
PGSDVKSYELITSESKMMQVIEEYIEDYNQINTAKLKLVLFMDAMSHICRISRTLRQALG
NALLLGVGGSGRSSLTRLASHMAEYECFQIELSKNYGMSEWRDDVKKVLLKAGLQNLPIT
FLFSDTQIKNESFLEDINNVLNSGDIPNLYTADEQDQIVSTMRPYIQEQGLQPTKANLMA
AYTGRVRSNIHMVLCMSPIGEVFRARLRQFPSLVNCCTIDWFNEWPAEALKSVATVFLNE
IPELESSQEEIQGLIQVCVYIHQSVSKKCIEYLAELTRHNYVTPKSYLELLHIFSILIGQ
KKLELKTAKNRMKSGLDKLLRTSEDVAKMQEDLESMHPLLEEAAKDTMLTMEQIKVDTAI
AEETRNSVQTEEIKANEKAKKAQAIADDAQKDLDEALPALDAALASLRNLNKNDVTEVRA
MQRPPPGVKLVIEAVCIMKGIKPKKVPGEKPGTKVDDYWEPGKGLLQDPGHFLESLFKFD
KDNIGDVVIKAIQPYIDNEEFQPATIAKVSKACTSICQWVRAMHKYHFVAKAVEPKRQAL
LEAQDDLGVTQRILDEAKQRLREVEDGIATMQAKYRECITKKEELELKCEQCEQRLGRAG
KLINGLSDEKVRWQETVENLQYMLNNISGDVLVAAGFVAYLGPFTGQYRTVLYDSWVKQL
RSHNVPHTSEPTLIGTLGNPVKIRSWQIAGLPNDTLSVENGVINQFSQRWTHFIDPQSQA
NKWIKNMEKDNGLDVFKLSDRDFLRSMENAIRFGKPCLLENVGEELDPALEPVLLKQTYK
QQGNTVLKLGDTVIPYHEDFRMYITTKLPNPHYTPEISTKLTLINFTLSPSGLEDQLLGQ
VVAEERPDLEEAKNQLIISNAKMRQELKDIEDQILYRLSSSEGNPVDDMELIKVLEASKM
KAAEIQAKVRIAEQTEKDIDLTRMEYIPVAIRTQILFFCVSDLANVDPMYQYSLEWFLNI
FLSGIANSERADNLKKRISNINRYLTYSLYSNVCRSLFEKHKLMFAFLLCVRIMMNEGKI
NQSEWRYLLSGGSISIMTENPAPDWLSDRAWRDILALSNLPTFSSFSSDFVKHLSEFRVI
FDSLEPHREPLPGIWDQYLDQFQKLLVLRCLRGDKVTNAMQDFVATNLEPRFIEPQTANL
SVVFKDSNSTTPLIFVLSPGTDPAADLYKFAEEMKFSKKLSAISLGQGQGPRAEAMMRSS
IERGKWVFFQNCHLAPSWMPALERLIEHINPDKVHRDFRLWLTSLPSNKFPVSILQNGSK
MTIEPPRGVRANLLKSYSSLGEDFLNSCHKVMEFKSLLLSLCLFHGNALERRKFGPLGFN
IPYEFTDGDLRICISQLKMFLDEYDDIPYKVLKYTAGEINYGGRVTDDWDRRCIMNILED
FYNPDVLSPEHSYSASGIYHQIPPTYDLHGYLSYIKSLPLNDMPEIFGLHDNANITFAQN
ETFALLGTIIQLQPKSSSAGSQGREEIVEDVTQNILLKVPEPINLQWVMAKYPVLYEESM
NTVLVQEVIRYNRLLQVITQTLQDLLKALKGLVVMSSQLELMAASLYNNTVPELWSAKAY
PSLKPLSSWVMDLLQRLDFLQAWIQDGIPAVFWISGFFFPQAFLTGTLQNFARKFVISID
TISFDFKVMFEAPSELTQRPQVGCYIHGLFLEGARWDPEAFQLAESQPKELYTEMAVIWL
LPTPNRKAQDQDFYLCPIYKTLTRAGTLSTTGHSTNYVIAVEIPTHQPQRHWIKRGVALI
CALDY
NT seq 12798 nt NT seq  +upstreamnt  +downstreamnt
atggagcagcctaacagtaaaggctatagcctgggaaggacccctcagggcccagagtgc
agcagtgctcctgcagtccaagtggggacccacaggggcctagagtataacccggggaag
attcttccaggatcagactatgggttgggaaatcctccagcccttgaccccaagctccca
catttacccctgcccccggccccacccacactctcagacttggggcagccacggaagtca
cccctgacaggcactgataagaagtacccgctgatgaagcagcgtgggttctactccgac
atcctcagccctggaaccttagatcaacttggggaggtatgtcgtggcccccgaatgagc
cagaacctcctgcggcaggctgaccttgacaagttcaccccaagagtcggaagctttgag
gttcctgaagacttccaggagcgcatggagcagcagtgcatcgggtccaccacccggctg
ctcgcccagactgacttcccactgcaggcctacgagcccaagatgcaggtgcctttccag
gtgctgccaggccagcatcctcgcaagattgagatcgagaggaggaaacagcagtacctg
agcctggacattgagcagttgctgttcagccagggcatcgactccaacaagctcatgccc
aggcacctggaccaccagcacccccaaaccatcgaacagggccatgacccaatcttcccc
atctacctcccactgaaggtatttgacaatgaggactttgactgccggactcccagagag
tggatcaacatgggcttggagccagggtctctggacaggaaacctgtcccgggaaaagcc
ctcttgcccactgatgacttcctggggcatgaggaccccaagagtcagaagctgaagtac
aaatggtgcgaggtcggcgtcctggactacgacgaggagaagaagctatacctggtacac
aagacagacgagaaaggcctggtgcgagatgagatggggaggcccatcctgaatgcaggg
gtcaccactgaaggaaggccaccccttcaggtctgtcagtactgggtgccacggatccag
cttctcttctgcgctgaggacccttgcatgttcgcacaacgtgtggtccaggccaacgcc
ctgcgcaagaacacggaagcactgctgctctacaacttgtatgtggactgcatgccctct
gacggccagcatgtcatcagtgaacagagcctgagcaagatcaagcagtgggccctgagc
acgcctcggatgcgcaaaggcccctcggttctagagcacctcagcagtcttgccagagaa
gtgagcctggactatgagcgcagcatgaacaagatcaactttgaccacgttgtctcttcc
aagcccgagaccttctcctacgtcaccctccccaagaaggaggaggagcaggtgcctgag
cgagggctggtgagtgtccccaagtaccacttctgggagcagaaggaggacttcactttc
gtgtccctgctcacacggccagaggtcatcacggccctcagcaaggtgagggccgagtgc
aacaaggtgaccgccatgtccctgttccactcgagcctctccaagtacagccacctggag
gaatttgagcagatccagtcacagaccttctcccaggtgcagatgttcctcaaggacagc
tggatcagctcgctaaaggtggccatgcgcagcagcctgcgcgacatgagcaagggctgg
tacaacctctacgagaccaactgggaggtgtacctcatgtccaagctgcgcaagctgatg
gagctggtgaagtacatgctgcaggacacactgcgcttcctggtgcaggactcacttgcc
agcttctcacagttcatcagcgacacctgttgcagcgtgctcaactgcaccgatgacatg
gtctggggtgacgacttaattaacagcccctacaggccccggaagaatcccctgttcatc
atggacctggtgctggacagctctggggtgcactatagcaccccactggagcagtttgag
gcatctctgctgaacctcttcgacaagggcatcctggccacccatgccgtgccccagctg
gagaagctggtgatggaggacatcttcatcagcggtgaccccctgctggagtccgtgggc
cttcatgagccactggtggaagagctacgggccaccattgccagtgccgtgtccaaggcc
atgatcccactgcaggcctacgccaaggagtaccgaaagtacctggagctgaacaacaat
gacattgcctcctttctcaaaacctaccagacgcagggcctgttggcccaggaggtgcgg
gaggtagtgctcacccacctgcgggagaaggagatcctggacagctcgctgcccagcagc
atcatcattgggcctttctacatcaacaccgacaatgtcaagcagagcctgtccaagaaa
cgcaaggccctggccacttccgtgctggacatccttgccaagaacctgcataaggaggtg
gatagcatctgcgaggagttccgcagcatcagccgcaagatctatgagaagcccaacagc
attgaggagctggctgagctgcgagagtggatgaagggcatcccggagaggctggtgggc
ctggaggagcggattgtgaaggtcatggatgactaccaggtcatggatgaattcctctac
aacctcagctcagatgacttcaatgacaaatggattgccagcaactggccttctaagatc
cttgggcagatagagctggtgcagcagcagcatgtggaggatgaggagaagttccgcaaa
atccagatcatggatcagaacaacttccaagagaagctggaagggctgcagctggtagta
gctggcttctccatccatgtggagatttcacgtgcacacgagatcgccaacgaggtgcgg
cgtgtcaagaagcagctgaaggactgccagcagctggccatgctctacaacaaccgcgag
cgcatcttcagcttgcccatcaccaattatgacaagctctccaggatggtgaaggagttc
caaccctacctggacctttggaccacagcgtctgactggctgcgctggtcggagagctgg
atgaatgaccccctctctgccatcgatgctgagcagctggagaagaacgtggttgaagcc
ttcaagaccatgcacaagtgcgtgaagcagtttaaggacatgccagcctgccaggaagtg
gccttggacatccgggcccgcatcgaggagttcaaaccatacatcccactgatccagggg
ctgcgcaaccctggcatgcggatccggcactgggagacactgtccaaccagatcaacatc
aatgtcaggcccaaggccaacctgacctttgctcgctgcctggagatgaacctgcaggac
catatcgagagcatcagcaaggtggctgaggtggctggcaaggagtacgccatcgagcag
gcactggacaagatggagaaggagtggtcgaccatcctgttcaatgtactgccctacaag
gcgacagacacctacatcctgaagagcccggacgaggcctcacagctgctggacgaccac
atcgtcatgacccagaatatgtcattttcaccctacaagaagccctttgagcagcgcatc
aactcctgggagaacaaactgaagctgacccaggaggttctggaggagtggctgaactgt
cagcggtcctggctctacctggagcccatctttagctctgaggacatcaaccagcagctg
cctgtggagagcaagcgctaccagaccatggagcggatctggaagaagatcatgaagaat
gcctacgagaaccgggaggtgatcaatgtgtgttccgacctgagaatgctggacagcctg
cgggactgcaacaagattctggacctggtgcagaagggcctcagcgagtatctggagacc
aagaggagcgccttccccagattctacttcctgtcagatgatgaactactagagatcttg
tcgcagacaaaggaccccacggccgtgcagccacacctgcgcaagtgcttcgagaacatc
gctcggctgctattccaggaggacctggagatcacgcacatgtactcagccgagggggag
gaggtacagttgtgcttctccatctacccctccagcaacgtggaggactggctgcgggag
gtggagcgcagcatgaaggccagtgtgcacgacatcattgagaaggccatcagggcctac
cccacgatgcccaggacccagtgggttctgaactggcctggccaggtgaccatcgctggg
tgccagacctactggaccatggaggtggcagaggctctggaggccggcaacctcagaagc
caactgttcccccagctctgccagcagctcagtgatctggtggcccttgtgcgggggaag
ctgtcccgcatgcagcgggcagtgctgtcagcgctaatcgtcattgaggtccatgccaag
gacgtggtgagcaagctaatccaggagaacgtggtcagcgtgaatgacttccagtggatc
tcacagctgaggtactactggacaaataatgacctgtatatccgtgctgtgaatgctgag
ttcatctatggctatgagtacctgggcaacagtgggaggctggtgatcacgcccctcacc
gacaggtgctacctgacactgaccggagctctgcacctcaagtttgggggtgccccagct
ggcccagctggcacaggcaaaactgagaccaccaaagacctgggtaaggccttggccata
cagaccgttgtgttcaactgctctgaccagctcgacttcatggccatgggcaagttcttc
aagggcctggccagtgctggggcctgggcctgcttcgacgagttcaatcgcatcgacatc
gaggtgctgtctgtggtggcgcagcagatcaccaccatccagaaggcgcagcagcagcgg
gtggaacgcttcatgtttgagggtgtggagatcccactggtgccatcctgcgcagtgttt
atcaccatgaacccgggctacgctggccgcacggagctgcctgacaatctgaaggcgctc
ttccgacccgtggccatgatggttccagattacgccatgatcactgagatctccctctat
tcctttggctttaatgaggccagtgtgctggctaagaagatcacaaccaccttcaagctg
tcttctgagcagctcagctcccaggatcactatgacttcgggatgagagccgtgaaaact
gtgatctcggctgctgggaacctcaagcgagaaaaccccagcatgaatgaggagctgatc
tgcctccgggccatccgtgatgtgaacgtgcccaagttcctgcaggaggacctcaagctc
ttctctggcatcgtgtccgacctgtttcccaccatcaaggaggaggacacggactacggc
atcctggatgaggccatccgcgaggcctgcaggaacagcaacctcaaggatgtggagggc
ttcctgacaaagtgcatccagctctacgagaccacggtggtacgacacggcctcatgctc
gtcgggcccacaggctccggcaagagtacttgttacagagtcctggcagctgccatgacg
tcactgaaagggcagccatccatcagtggtggcatgtacgaggctgtcaactactacgtg
ctcaaccccaagtccatcacgatgggccagctgtacggggagtttgacctcctcacccat
gagtggacagacgggatattctcctcgttcatccgggcgggggccatcacctccgacacc
aacaagaagtggtacatgttcgatgggccggtggatgccatctggattgagaacatgaac
acggtgctggatgacaacaagaagctgtgcctcagctctggggagatcatcaagctcaca
gaggcaatgaccatgatgttcgaggtgcaagacctggcggtggcttcaccagctacagtc
tcccgctgtggcatggtgtacctggagcccagcatcctggggctcatgcccttcatcgag
tgctggctgaggaagctgcctcccttgctgaagccctatgaggagcatttcaaggccctc
tttgtcagcttcctggaggaatccatctccttcgttcggtcctcagtgaaggaggtgatc
gcctcaaccaactgcaacctgaccatgagcctcctcaagctgctggactgcttcttcaag
ccctttctgcctagagagggcctcaagaaaataccctctgaaaagctgagtcgcatcgta
gagttgatcgagccctggttcatcttctccctgatctggagcgtgggtgccactggggac
agcagtggccgcaccagtttcagccactggctaaggctcaagatggagaacgaacagctg
actctgcttttcccagaagaggggctggtgttcgattacaggctggaggacgcgggcatc
agtggcaccaacgacagtgaggatgaagaggaggaatacaagcaggttgcctgggtgaag
tggatggactcctcagctccattcaccatggtaccagacaccaactactgcaacatcatt
gtgcccaccatggacaccgtgcagatgtcccatttactggacatgctgctcaccaacaag
aagcccgtgctgtgcattgggccaacaggcacggggaagacgctcaccatctctgacaag
ctcctcaagaacctggcactggattacatcagccacttcctcaccttctcagcccgcact
tcagccaaccagacccaggacttcattgacagcaagctggacaagaggcggaagggtgtg
tttggaccacctctggggcgcaactttatcttcttcatcgatgacctgaacatgccggcc
ctggagacctacggtgcacagccacccatcgagctgttgcgccagtggatggaccacggc
ggctggtacgaccgcaagatcattggtgccttcaagaacctagtggacatcaactttgtc
tgtgccatgggccccccgggtggaggcaggaacaccgtcaccccgcggctgatgcgtcac
ttcaactacctgtctttcgctgagatggacgaggtcagcaagaaacgcatcttctccacc
atcctgggcaactggttggatggactccttggagaaaaaagctaccgggagcgtgtgcct
ggggccccccacattgcccacttcacggagccccttgtggaagccaccatcatggtgtat
gcaaccatcacctcccagctgctgcccactccagccaagtcccactacaccttcaacctg
agggacctctccaaggtcttccaaggcatgctcatggctgacccggccaaggtcgaggac
caagtgcagctgctgcgactgtggtatcacgagaactgccgcgtgttccgggaccgactg
gtgaatgaggaggaccgcagctggttcgaccagctcctcaagcgctgcatggagcagtgg
gaggtgaccttcaacaaggtctgccccttccagcccattctttacggggacttcatgtca
ccaggctccgatgtcaagtcctacgagctcatcaccagtgagagtaagatgatgcaggtg
atagaggagtacatagaggactacaaccagatcaacacggccaagctgaagctggtcctc
ttcatggacgccatgagccacatctgtcgcatcagccgcaccctacgccaggcgctgggc
aatgcactcctgctgggcgtgggtggcagcggccgcagctccctcacaaggctcgcctcg
cacatggccgagtacgagtgcttccagattgaactatccaagaactacggcatgtccgag
tggcgagatgatgtgaagaaggtcctgctcaaggcgggcctacagaacctacccatcacc
ttcctcttctcagacacccagatcaagaacgaatccttcctggaagatatcaacaacgtc
ctaaactctggtgacattcccaatctgtatactgcggacgagcaggaccagatcgtcagc
accatgcggccctatatccaggagcagggcctacagcccaccaaggccaacctcatggct
gcttacacagggcgtgtgcgcagcaacatccacatggtgctgtgcatgagccccatcgga
gaggtcttccgagctcgtctgaggcagtttccctccctggtcaactgctgtaccatcgac
tggtttaacgagtggccggcagaagccctgaagtctgtggccaccgtgttcctcaatgag
atcccagaactggaatcctcccaggaagaaatccaaggactgatccaggtctgtgtgtac
atccaccagtcggtgtccaagaagtgcatcgagtacctggcagagctgacccgccacaac
tatgtgacccccaagagctacttggagctgcttcatattttctccatcctcatcgggcag
aagaaactggagctgaaaactgccaagaaccgcatgaagagcggcctcgacaagctgctg
cgcacttctgaggatgtagccaagatgcaggaggacctggagagtatgcaccccctgctg
gaggaggctgccaaggacaccatgctcaccatggagcagatcaaggtggatacggccatc
gccgaggagacccggaattcagtgcagacagaggagatcaaagccaatgagaaggccaag
aaggcacaagctattgctgacgatgcccagaaggacctggacgaggcgttgccagccctg
gatgcggctctggccagcctgcgcaacctcaacaagaacgatgtgaccgaggtacgtgcc
atgcagcggccacccccgggtgtgaaactggtcatagaagctgtgtgcattatgaaaggc
atcaagcccaagaaggtgcctggagaaaagccaggcaccaaggtggatgactactgggag
cctggcaaggggctgctgcaggacccgggccacttccttgagagcctcttcaagtttgac
aaggacaacattggggatgtggtgatcaaagccatccagccgtacatcgataatgaagag
ttccagccagccaccattgccaaggtgtccaaggcttgcacctccatctgccagtgggtg
cgcgccatgcacaagtaccactttgtggccaaggccgtggagcccaagcggcaagccctg
ctggaggcccaggatgacctgggggtgacacagaggatcctggatgaggcaaaacagcgc
cttcgtgaggtggaggacggcatcgccacaatgcaggctaagtaccgggaatgcattacc
aagaaggaggagctggagctgaagtgtgagcagtgtgagcagcggctgggccgagctggc
aagctcatcaacgggctgtcggatgagaaggtgcgctggcaggagacggtggagaacctg
cagtacatgctcaacaacatctccggcgatgtcctggtggccgctggctttgtggcctac
ctgggccccttcacgggccagtaccgcacggtgctctacgacagctgggtcaagcagctc
aggagccacaatgtcccacacacctccgagcccacgctaatcgggacgctggggaaccct
gtgaagatccgatcgtggcagatcgctggcctccccaacgacacactgtcagtggagaac
ggggtcatcaaccagttttcccagcgctggacccacttcattgaccctcagagccaggcc
aacaaatggatcaagaacatggagaaggacaatgggctggatgtgttcaagttgagtgac
cgcgacttcctgcgcagcatggagaacgccatccgctttggcaagccatgtctcctggag
aacgtgggcgaggagctagacccagccctggagccagtgctgctcaagcagacgtacaag
cagcagggaaacacggtgctgaagctgggggacacggtgatcccctaccatgaggacttc
aggatgtacatcaccaccaagctgcccaacccacactacacgcccgagatctccaccaaa
ctcaccctcatcaacttcaccctgtcgcccagtggcctagaggaccagctactgggccag
gtagtggcagaggagcgacccgacctggaggaggccaagaaccagctgattatcagtaat
gccaagatgcgccaggagctgaaggacattgaggaccagatcctgtaccggctcagctcc
tccgagggcaaccctgtagatgacatggaactcatcaaggtgctggaagcctccaagatg
aaggctgctgagatccaggccaaagtcaggattgcagagcagacggagaaggacatcgac
ctgacgcgcatggagtacatacccgtggccatccgcacccagatcctcttcttctgtgtg
tccgacctggccaacgtggaccccatgtaccagtactcccttgagtggtttctcaacatc
ttcctctcgggcatcgccaactcagagagagcagacaacctgaagaagcgcatctccaac
atcaaccgctacctgacctacagcctctacagcaacgtctgccgcagcctctttgagaag
cacaagctgatgtttgccttcctgctgtgtgttcgcatcatgatgaacgagggcaaaatc
aaccagagtgagtggcgatacctcctgtctgggggctccatctcgatcatgactgagaat
ccggcaccggactggctgtcagaccgggcttggcgagacatcctagcactctcgaacctg
ccaaccttttcctccttctcttccgacttcgtgaagcacctctcagaattccgggtcatc
ttcgacagccttgagccccaccgggagcctttgcctggcatctgggaccagtacctagac
cagttccagaagctgctagtcctccgctgcctgcgtggggacaaggttaccaacgccatg
caggactttgtggccaccaacctggagccacgcttcattgaaccccagacagccaatctg
tcagtggtgttcaaagactccaactccaccacacccctcatctttgtgctgtcacccggc
acagaccctgctgccgacctctacaagtttgccgaagaaatgaagttctccaaaaagctc
tctgccatctccctgggccaggggcagggccctcgggcagaagccatgatgcgcagctcc
atagagaggggcaaatgggtcttcttccagaactgccacctggcaccaagctggatgcca
gccctagaacgcctcatcgagcacatcaaccccgacaaggtacacagggacttccgcctc
tggctcaccagcctgcccagcaacaagttcccagtgtccatcctgcagaacggctccaag
atgaccattgagccgccacgcggtgtcagggccaacctgctgaagtcctatagtagcctt
ggtgaagacttcctcaactcctgccacaaggtgatggagttcaagtctctgctgctgtct
ctgtgcttgttccatgggaacgccctggagcgccgtaagtttgggcccctgggcttcaac
atcccctatgagttcacggatggagatctgcgcatctgcatcagccagctcaagatgttc
ctggacgaatatgatgacatcccctacaaggtcctcaagtacacggcaggggagatcaat
tacgggggccgtgtcactgatgactgggaccggcgctgcatcatgaacatcttggaggac
ttctacaaccctgacgtgctctcccctgagcacagctacagcgcctcgggcatctaccac
cagatcccgcctacctacgacctccacggctacctctcctacatcaagagcctcccactc
aatgatatgcctgagatctttggcctgcatgacaatgccaacatcacctttgcccagaac
gagacgttcgccctcctgggcaccatcatccagctgcaacccaaatcatcttctgcaggc
agccagggccgggaggagatagtggaggacgtcacccaaaacattctgctcaaggtgcct
gagcctatcaacttgcaatgggtgatggccaagtacccagtgctgtatgaggaatcaatg
aacacagtactagtacaagaggtcattaggtacaatcggctgctgcaggtgatcacacag
acactgcaagacctactcaaggcactcaaggggctggtagtgatgtcctctcagctggag
ctgatggctgccagcctgtacaacaatactgtgcctgagctctggagtgccaaggcctac
ccatcgctcaagcctctgtcatcatgggtcatggacctgctgcaacgcctggactttctg
caggcctggatccaagatggcatcccagctgtcttctggatcagtggattcttcttcccc
caggctttcttaacaggcactctgcagaattttgcccgcaaatttgtcatctccattgac
accatctcctttgatttcaaggtgatgtttgaggcaccatcagagttaacacaaagaccc
caagtagggtgctatatccatggattattcctggaaggtgcccgctgggatccagaggcc
ttccagctggctgagtctcagcccaaggagctgtacacagagatggccgttatctggctc
ttgccaacacccaaccgcaaggcccaggaccaggacttttacctgtgccccatctacaag
acactgactcgtgctggaacactatcaaccacaggacactctaccaactatgtcattgct
gtggagatccccacccatcagccccagcgacactggataaagcgtggtgtggccctcatc
tgtgccctggactactag

KEGG   Homo sapiens (human): 27019Help
Entry
27019             CDS       T01001                                 

Gene name
DNAI1, CILD1, DIC1, ICS1, PCD
Definition
(RefSeq) dynein axonemal intermediate chain 1
  KO
K10409  dynein intermediate chain 1, axonemal
Organism
hsa  Homo sapiens (human)
Pathway
hsa05016  Huntington disease
Disease
H00564  Primary ciliary dyskinesia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09164 Neurodegenerative disease
   05016 Huntington disease
    27019 (DNAI1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    27019 (DNAI1)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    Dyneins
     27019 (DNAI1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: WD40
Motif
Other DBs
NCBI-GeneID: 27019
NCBI-ProteinID: NP_036276
OMIM: 604366
HGNC: 2954
Ensembl: ENSG00000122735
Vega: OTTHUMG00000019825
Pharos: Q9UI46(Tbio)
UniProt: Q9UI46 A0A140VJI0
Position
9p13.3
AA seq 699 aa AA seqDB search
MIPASAKAPHKQPHKQSISIGRGTRKRDEDSGTEVGEGTDEWAQSKATVRPPDQLELTDA
ELKEEFTRILTANNPHAPQNIVRYSFKEGTYKPIGFVNQLAVHYTQVGNLIPKDSDEGRR
QHYRDELVAGSQESVKVISETGNLEEDEEPKELETEPGSQTDVPAAGAAEKVTEEELMTP
KQPKERKLTNQFNFSERASQTYNNPVRDRECQTEPPPRTNFSATANQWEIYDAYVEELEK
QEKTKEKEKAKTPVAKKSGKMAMRKLTSMESQTDDLIKLSQAAKIMERMVNQNTYDDIAQ
DFKYYDDAADEYRDQVGTLLPLWKFQNDKAKRLSVTALCWNPKYRDLFAVGYGSYDFMKQ
SRGMLLLYSLKNPSFPEYMFSSNSGVMCLDIHVDHPYLVAVGHYDGNVAIYNLKKPHSQP
SFCSSAKSGKHSDPVWQVKWQKDDMDQNLNFFSVSSDGRIVSWTLVKRKLVHIDVIKLKV
EGSTTEVPEGLQLHPVGCGTAFDFHKEIDYMFLVGTEEGKIYKCSKSYSSQFLDTYDAHN
MSVDTVSWNPYHTKVFMSCSSDWTVKIWDHTIKTPMFIYDLNSAVGDVAWAPYSSTVFAA
VTTDGKAHIFDLAINKYEAICNQPVAAKKNRLTHVQFNLIHPIIIVGDDRGHIISLKLSP
NLRKMPKEKKGQEVQKGPAVEIAKLDKLLNLVREVKIKT
NT seq 2100 nt NT seq  +upstreamnt  +downstreamnt
atgattcctgcttctgcgaaggctccccataaacagcctcataagcagagcatcagcata
ggcagaggaaccaggaagagagatgaagattcagggactgaagtgggagaaggcacagat
gaatgggcccaatccaaagccacagttagaccccctgaccagctggagttgaccgatgcg
gagttaaaggaggagttcactcggattttgacagccaacaacccacacgcaccccagaac
attgtcaggtacagcttcaaagaaggcacatataagcctattggctttgtgaaccaactg
gcagttcactacacccaggttgggaacctgatccccaaagactcagatgaaggacggcgg
cagcattaccgcgatgaattagtggcaggttctcaggagtctgtcaaggtgatttcagaa
acaggaaacctcgaagaagacgaagagcccaaggagttagaaactgagcctgggagtcaa
acagatgtgcctgcagctggggcagctgaaaaagtgactgaagaagaattgatgactcct
aagcagcccaaggagagaaagctcactaaccagttcaacttcagtgagagggcctcacag
acctacaacaaccctgtccgggatcgagaatgccagacggagcctcctcccaggacaaac
ttttcagccacagccaatcagtgggagatctatgatgcctatgtagaggaacttgagaag
caggaaaagaccaaagagaaggagaaggcaaagaccccagtggctaaaaaatcagggaag
atggccatgaggaagctgacatctatggagtctcagactgatgatctcatcaaattgtcc
caagctgctaagatcatggagcggatggtcaaccagaatacatatgatgacattgctcaa
gattttaagtactatgacgatgctgctgatgaataccgggaccaggtgggtaccctgctg
ccgctctggaagttccaaaatgacaaagccaagcgcctgtccgtcactgccctctgctgg
aatccaaagtacagggatctgtttgcagtgggatatggctcttatgacttcatgaagcag
agccggggcatgctgctgctctacagcctgaagaaccccagcttccctgagtacatgttc
agcagcaacagcggcgtcatgtgtctcgacatccacgtggaccacccctacctggtggca
gtaggccactatgacggcaacgtggccatttacaacctcaagaagccccactcccagccc
tccttctgcagctcagccaagtctggcaagcactcagaccctgtgtggcaggtcaagtgg
cagaaggatgacatggaccaaaaccttaacttcttctctgtgtcatctgacggcaggatt
gtgtcttggactctcgtgaagagaaagctggttcacatagatgtcatcaagctgaaggtg
gaaggcagcaccacggaagttcctgaggggttgcagctgcacccagtgggttgtggcact
gcctttgacttccacaaagagattgactacatgttcctagtgggcacagaggagggaaaa
atctacaagtgctctaaatcctactccagccaattcctcgacacctatgacgcccacaac
atgtcagtggacactgtgtcctggaacccataccacaccaaggtcttcatgtcctgcagc
tccgactggacagtgaagatctgggaccacaccatcaagaccccgatgttcatctatgac
ctgaactcagccgtgggtgatgtggcctgggcgccatactcttctactgtgttcgcagca
gtcaccacagatgggaaggcccacatatttgacttagccatcaacaagtatgaggccatc
tgcaaccagcctgtggcggccaaaaagaacaggctcacccacgtgcagttcaatctcatc
caccccatcatcattgtgggcgatgaccgtgggcacatcatcagcctcaagctctcaccc
aatttgcgcaagatgccaaaggaaaagaaggggcaggaggtgcagaagggtccagctgtg
gagattgcgaaactggacaaactgctgaacctggtgagggaagtgaaaatcaagacctga

KEGG   Homo sapiens (human): 55567Help
Entry
55567             CDS       T01001                                 

Gene name
DNAH3, DNAHC3-B, DNAHC3B, HDHC8, HEL-36, HSADHC3
Definition
(RefSeq) dynein axonemal heavy chain 3
  KO
K10408  dynein heavy chain, axonemal
Organism
hsa  Homo sapiens (human)
Pathway
hsa05016  Huntington disease
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09164 Neurodegenerative disease
   05016 Huntington disease
    55567 (DNAH3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    55567 (DNAH3)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    Dyneins
     55567 (DNAH3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: AAA_6 DHC_N2 Dynein_C AAA_8 AAA_9 AAA_7 AAA_lid_11 MT Dynein_heavy Dynein_AAA_lid AAA_lid_1 AAA_5 AAA Spc7 T2SSE ARL2_Bind_BART
Motif
Other DBs
NCBI-GeneID: 55567
NCBI-ProteinID: NP_060009
OMIM: 603334
HGNC: 2949
Ensembl: ENSG00000158486
Vega: OTTHUMG00000090677
Pharos: Q8TD57(Tdark)
UniProt: Q8TD57
Position
16p12.3
AA seq 4116 aa AA seqDB search
MGATGRLELTLAAPPHPGPAFQRSKARETQGEEEGSEMQIAKSDSIHHMSHSQGQPELPP
LPASANEEPSGLYQTVMSHSFYPPLMQRTSWTLAAPFKEQHHHRGPSDSIANNYSLMAQD
LKLKDLLKVYQPATISVPRDRTGQGLPSSGNRSSSEPMRKKTKFSSRNKEDSTRIKLAFK
TSIFSPMKKEVKTSLTFPGSRPMSPEQQLDVMLQQEMEMESKEKKPSESDLERYYYYLTN
GIRKDMIAPEEGEVMVRISKLISNTLLTSPFLEPLMVVLVQEKENDYYCSLMKSIVDYIL
MDPMERKRLFIESIPRLFPQRVIRAPVPWHSVYRSAKKWNEEHLHTVNPMMLRLKELWFA
EFRDLRFVRTAEILAGKLPLQPQEFWDVIQKHCLEAHQTLLNKWIPTCAQLFTSRKEHWI
HFAPKSNYDSSRNIEEYFASVASFMSLQLRELVIKSLEDLVSLFMIHKDGNDFKEPYQEM
KFFIPQLIMIKLEVSEPIIVFNPSFDGCWELIRDSFLEIIKNSNGIPKLKYIPLKFSFTA
AAADRQCVKAAEPGEPSMHAAATAMAELKGYNLLLGTVNAEEKLVSDFLIQTFKVFQKNQ
VGPCKYLNVYKKYVDLLDNTAEQNIAAFLKENHDIDDFVTKINAIKKRRNEIASMNITVP
LAMFCLDATALNHDLCERAQNLKDHLIQFQVDVNRDTNTSICNQYSHIADKVSEVPANTK
ELVSLIEFLKKSSAVTVFKLRRQLRDASERLEFLMDYADLPYQIEDIFDNSRNLLLHKRD
QAEMDLIKRCSEFELRLEGYHRELESFRKREVMTTEEMKHNVEKLNELSKNLNRAFAEFE
LINKEEELLEKEKSTYPLLQAMLKNKVPYEQLWSTAYEFSIKSEEWMNGPLFLLNAEQIA
EEIGNMWRTTYKLIKTLSDVPAPRRLAENVKIKIDKFKQYIPILSISCNPGMKDRHWQQI
SEIVGYEIKPTETTCLSNMLEFGFGKFVEKLEPIGAAASKEYSLEKNLDRMKLDWVNVTF
SFVKYRDTDTNILCAIDDIQMLLDDHVIKTQTMCGSPFIKPIEAECRKWEEKLIRIQDNL
DAWLKCQATWLYLEPIFSSEDIIAQMPEEGRKFGIVDSYWKSLMSQAVKDNRILVAADQP
RMAEKLQEANFLLEDIQKGLNDYLEKKRLFFPRFFFLSNDELLEILSETKDPLRVQPHLK
KCFEGIAKLEFTDNLEIVGMISSEKETVPFIQKIYPANAKGMVEKWLQQVEQMMLASMRE
VIGLGIEAYVKVPRNHWVLQWPGQVVICVSSIFWTQEVSQALAENTLLDFLKKSNDQIAQ
IVQLVRGKLSSGARLTLGALTVIDVHARDVVAKLSEDRVSDLNDFQWISQLRYYWVAKDV
QVQIITTEALYGYEYLGNSPRLVITPLTDRCYRTLMGALKLNLGGAPEGPAGTGKTETTK
DLAKALAKQCVVFNCSDGLDYKAMGKFFKGLAQAGAWACFDEFNRIEVEVLSVVAQQILS
IQQAIIRKLKTFIFEGTELSLNPTCAVFITMNPGYAGRAELPDNLKALFRTVAMMVPDYA
LIGEISLYSMGFLDSRSLAQKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKY
PEENESVLLLRALLDVNLAKFLAQDVPLFQGIISDLFPGVVLPKPDYEVFLKVLNDNIKK
MKLQPVPWFIGKIIQIYEMMLVRHGYMIVGDPMGGKTSAYKVLAAALGDLHAANQMEEFA
VEYKIINPKAITMGQLYGCFDQVSHEWMDGVLANAFREQASSLSDDRKWIIFDGPVDAIW
IENMNTVLDDNKKLCLMSGEIIQMNSKMSLIFEPADLEQASPATVSRCGMIYMEPHQLGW
KPLKDSYMDTLPSSLTKEHKELVNDMFMWLVQPCLEFGRLHCKFVVQTSPIHLAFSMMRL
YSSLLDEIRAVEEEEMELGEGLSSQQIFLWLQGLFLFSLVWTVAGTINADSRKKFDVFFR
NLIMGMDDNHPRPKSVKLTKNNIFPERGSIYDFYFIKQASGHWETWTQYITKEEEKVPAG
AKVSELIIPTMETARQSFFLKTYLDHEIPMLFVGPTGTGKSAITNNFLLHLPKNTYLPNC
INFSARTSANQTQDIIMSKLDRRRKGLFGPPIGKKAVVFVDDLNMPAKEVYGAQPPIELL
RQWIDHGYWFDKKDTTRLDIVDMLLVTAMGPPGGGRNDITGRFTRHLNIISINAFEDDIL
TKIFSSIVDWHFGKGFDVMFLRYGKMLVQATKTIYRDAVENFLPTPSKSHYVFNLRDFSR
VIQGVLLCPHTHLQDVEKCIRLWIHEVYRVFYDRLIDKEDRQVFFNMVKETTSNCFKQTI
EKVLIHLSPTGKIVDDNIRSLFFGDYFKPESDQKIYDEITDLKQLTVVMEHYLEEFNNIS
KAPMSLVMFRFAIEHISRICRVLKQDKGHLLLVGIGGSGRQSAAKLSTFMNAYELYQIEI
TKNYAGNDWREDLKKIILQVGVATKSTVFLFADNQIKDESFVEDINMLLNTGDVPNIFPA
DEKADIVEKMQTAARTQGEKVEVTPLSMYNFFIERVINKISFSLAMSPIGDAFRNRLRMF
PSLINCCTIDWFQSWPTDALELVANKFLEDVELDDNIRVEVVSMCKYFQESVKKLSLDYY
NKLRRHNYVTPTSYLELILTFKTLLNSKRQEVAMMRNRYLTGLQKLDFAASQVAVMQREL
TALQPQLILTSEETAKMMVKIEAETREADGKKLLVQADEKEANVAAAIAQGIKNECEGDL
AEAMPALEAALAALDTLNPADISLVKSMQNPPGPVKLVMESICIMKGMKPERKPDPSGSG
KMIEDYWGVSKKILGDLKFLESLKTYDKDNIPPLTMKRIRERFINHPEFQPAVIKNVSSA
CEGLCKWVRAMEVYDRVAKVVAPKRERLREAEGKLAAQMQKLNQKRAELKLVVDRLQALN
DDFEEMNTKKKDLEENIEICSQKLVRAEKLISGLGGEKDRWTEAARQLGIRYTNLTGDVL
LSSGTVAYLGAFTVDYRVQCQNQWLAECKDKVIPGFSDFSLSHTLGDPIKIRAWQIAGLP
VDSFSIDNGIIVSNSRRWALMIDPHGQANKWIKNMEKANKLAVIKFSDSNYMRMLENALQ
LGTPVLIENIGEELDASIEPILLKATFKQQGVEYMRLGENIIEYSRDFKLYITTRLRNPH
YLPEVAVKVCLLNFMITPLGLQDQLLGIVAAKEKPELEEKKNQLIVESAKNKKHLKEIED
KILEVLSMSKGNILEDETAIKVLSSSKVLSEEISEKQKVASMTETQIDETRMGYKPVAVH
SATIFFCISDLANIEPMYQYSLTWFINLYMHSLTHSTKSEELNLRIKYIIDHFTLSIYNN
VCRSLFEKDKLLFSLLLTIGIMKQKKEITEEVWYFLLTGGIALDNPYPNPAPQWLSEKAW
AEIVRASALPKLHGLMEHLEQNLGEWKLIYDSAWPHEEQLPGSWKFSQGLEKMVILRCLR
PDKMVPAVREFIAEHMGKLYIEAPTFDLQGSYNDSSCCAPLIFVLSPSADPMAGLLKFAD
DLGMGGTRTQTISLGQGQGPIAAKMINNAIKDGTWVVLQNCHLAASWMPTLEKICEEVIV
PESTNARFRLWLTSYPSEKFPVSILQNGIKMTNEPPKGLRANLLRSYLNDPISDPVFFQS
CAKAVMWQKMLFGLCFFHAVVQERRNFGPLGWNIPYEFNESDLRISMWQIQMFLNDYKEV
PFDALTYLTGECNYGGRVTDDKDRRLLLSLLSMFYCKEIEEDYYSLAPGDTYYIPPHGSY
QSYIDYLRNLPITAHPEVFGLHENADITKDNQETNQLFEGVLLTLPRQSGGSGKSPQEVV
EELAQDILSKLPRDFDLEEVMKLYPVVYEESMNTVLRQELIRFNRLTKVVRRSLINLGRA
IKGQVLMSSELEEVFNSMLVGKVPAMWAAKSYPSLKPLGGYVADLLARLTFFQEWIDKGP
PVVFWISGFYFTQSFLTGVSQNYARKYTIPIDHIGFEFEVTPQETVMENNPEDGAYIKGL
FLEGARWDRKTMQIGESLPKILYDPLPIIWLKPGESAMFLHQDIYVCPVYKTSARRGTLS
TTGHSTNYVLSIELPTDMPQKHWINRGVASLCQLDN
NT seq 12351 nt NT seq  +upstreamnt  +downstreamnt
atgggagctacagggcgcctcgagctcacactggccgcccctccccatccgggcccagcc
tttcagcgttcaaaagccagggagacccaaggagaggaggaagggagtgaaatgcagatc
gccaaaagtgactccatacatcacatgagccactcccaggggcagccagagctgcctcct
ctgcctgcttctgctaatgaggaaccgtctggactctatcagactgtcatgtcacacagc
ttttacccgcccttgatgcaacgcacgtcatggaccttggctgcacccttcaaagaacag
catcaccaccgtggacccagtgattccatcgccaacaactactccttgatggcccaggac
ctgaagctgaaagatctgctgaaggtctaccaaccggccaccatcagtgtccctagggac
aggaccggtcaggggctgccatcatcaggaaatagaagctcatcagagcccatgaggaaa
aaaacgaagttttcctccagaaacaaagaggattccactaggatcaagttggccttcaag
acgtcaatcttctcacccatgaagaaggaggtaaagacatctttgacgttcccaggaagc
agaccaatgagtccagaacagcagctcgatgtcatgttacagcaggagatggaaatggaa
agtaaagaaaagaagccatctgaatcggacctggagagatactattactatctgaccaat
ggaattcgcaaagacatgattgcccctgaggagggtgaagtgatggttcggatttcaaag
ctgatttctaacacgctgctgacgagtcccttcctggagcccctgatggtggtcctcgtg
caggagaaggagaatgactattactgtagcctcatgaaaagcatcgttgattacatcctc
atggacccaatggagagaaaacggctctttattgagagcatcccccgcttgtttcctcaa
agagtgatccgggcccctgtgccctggcacagtgtctacaggagcgccaagaagtggaac
gaggagcatctgcacacggtgaaccccatgatgctcaggctgaaagaactgtggtttgca
gaattcagagacctcaggtttgttcgaacagcagaaatactagcgggaaaattgcctctg
cagcctcaggaattttgggatgtgatccagaaacactgcctggaggcacaccagactctt
ctcaacaagtggatccccacctgcgcccagctttttacctcacggaaggagcactggatt
cattttgctcccaagagcaactatgactcaagtcgaaacattgaggaatattttgcttct
gtggcatcattcatgtcgctgcagcttagggagctggtcattaagtcacttgaggacctc
gtttcccttttcatgatacacaaagatgggaatgattttaaggagccctaccaagagatg
aagtttttcatacctcagctaatcatgatcaaacttgaagtcagtgaacccattattgtc
ttcaatccatcttttgatggctgctgggaattaatacgtgactctttcctggaaattatt
aagaactctaatgggatccccaagctgaaatacataccacttaagttctccttcactgct
gctgctgctgatcggcaatgtgtgaaagcagctgagccaggagagcccagcatgcacgcg
gctgccactgcaatggcagagctgaaaggatataatctgctccttggaactgttaacgca
gaagaaaaacttgtttctgattttttgattcaaactttcaaggtatttcagaaaaatcaa
gttggcccctgcaaatatttaaatgtctacaaaaagtatgttgacttattggataacacg
gcagagcaaaacatcgctgcgttcctgaaagaaaatcatgacattgatgattttgtgacg
aagatcaatgccataaagaaacggagaaatgaaattgcatccatgaacatcaccgtgcct
ttagccatgttctgccttgatgctacggccctaaatcatgatctctgtgagcgagctcaa
aatcttaaagaccatctgattcaattccaagtggatgtaaaccgagacaccaataccagc
atttgtaatcagtacagccacatcgcagacaaagtcagtgaggttcctgccaacactaag
gagctggtatccctcattgaattcctaaagaaatccagtgctgtcactgtgttcaaactc
aggaggcaacttagagatgcaagtgaacggctggagttcctgatggactatgcagacttg
ccgtaccagattgaagatatctttgacaacagccggaacttgctccttcacaagagggat
caggcagaaatggatctgattaaaagatgctcagaatttgagttgagacttgagggctac
cacagagaactggaaagttttaggaagcgcgaagtgatgactacagaagaaatgaagcac
aatgttgaaaagcttaatgagctttcaaagaacctaaatcgggcgtttgcagagtttgag
ttgatcaataaggaggaagagctattggaaaaggagaagagtacttaccctcttctgcag
gccatgctgaagaacaaagtaccttatgagcagctgtggtcgacagcctatgagttcagc
atcaagtcagaggaatggatgaatggacccctcttcttactgaatgctgagcaaattgcg
gaggagatagggaatatgtggaggacaacgtataaactgatcaagaccttgtctgatgtg
cctgcacccaggcgcttagcagagaatgtgaagatcaagatcgataagttcaagcagtac
attcccatcctcagtatttcctgcaacccaggaatgaaagaccgacactggcagcagatc
agtgagattgttggctatgagataaagcccaccgaaacgacctgcctctcaaatatgctc
gaatttggattcggcaaattcgttgaaaaattggagcccattggtgcagctgccagcaag
gaatactctctggagaaaaacttggatagaatgaagttggattgggttaacgtgacgttc
agcttcgtgaaatacagggacactgatacaaacatcttgtgtgcaattgatgacattcaa
atgctacttgatgatcacgtgataaagacccagaccatgtgtggctccccattcatcaaa
ccaatagaagcagaatgccggaaatgggaagaaaagctaattcgcatacaagacaatttg
gatgcctggttgaaatgccaagccacctggctgtacctggaaccaatcttcagttcagag
gacatcatagcccagatgccagaagaggggaggaaatttggcattgttgatagttactgg
aaatcacttatgtcccaagcggtgaaagataacaggattctggtggcagccgaccagcca
cggatggcagagaagcttcaagaagccaactttctcttggaggacatccagaaagggctg
aatgattacttggagaagaagagactattcttccccagattcttcttcctatcaaacgat
gagctgctggaaatcttgtccgagacaaaggaccctctccgagtgcagccgcacttgaag
aagtgctttgaaggaattgccaagcttgagtttacagacaatctggaaattgtgggcatg
atcagctcggaaaaagaaactgttccattcatacagaaaatctacccagctaatgccaag
ggcatggtggaaaagtggctccagcaggtggagcagatgatgctggccagtatgcgagaa
gtcattggacttgggattgaagcatatgtcaaggtccctcgaaatcactgggtcttacag
tggcctggacaggtggttatctgtgtctcctccatcttttggacccaggaggtgtcccaa
gccctggcggaaaataccttactggattttctgaaaaagagcaatgatcagattgcgcag
attgtccagctggtgcgagggaagctgagcagtggagctcgactcactctcggggccctc
acggtcatcgatgtccacgcccgcgacgtggtggccaagttatctgaggacagggtctcc
gatctgaatgatttccaatggatctcacagctgcgctactactgggtggccaaggatgtg
caggtgcagattatcaccacagaagccttgtatggctatgagtacctgggaaactccccc
cggctggtgatcacacccctcaccgaccgctgctacaggacactgatgggagctttgaag
ctgaaccttgggggtgctccagagggtccagctgggactggcaagacagaaaccaccaaa
gatttggccaaagccttggctaagcagtgtgtggtcttcaactgctccgatggtttggat
tacaaagctatggggaagttcttcaaggggctggcacaggctggagcatgggcgtgcttt
gatgagttcaacaggatcgaggtagaagtgctgtctgtggtcgctcagcagatcctcagc
atccaacaagccatcattcggaagctaaagacattcatctttgaagggactgagctctct
ctgaacccaacctgcgctgtgttcatcaccatgaaccccgggtatgctggcagggctgaa
ctgcccgacaatctcaaggccttgttccggacagtggccatgatggtcccagattacgcc
ctcattggagaaatctccctctactccatggggtttctggactccagaagtctcgcccag
aagatcgttgcgacctaccgcctgtgctcggaacaactgtcctctcagcatcactatgac
tacggtatgcgcgctgtcaagtctgtgcttactgccgcaggaaacctgaagctcaagtat
ccagaggagaatgaaagtgtcctgctgctccgggcattgcttgatgtcaatctggccaag
ttcttagcgcaagatgtccctctgtttcagggaattatatctgatttatttcctggagtt
gttcttccaaagccagactatgaagtttttctgaaagtgctgaatgataacatcaaaaag
atgaaactccagccagtaccttggtttatagggaaaattatccagatctacgaaatgatg
ctggtgagacatggctatatgattgtaggagaccccatgggcggcaagacctctgcttat
aaagtgttggctgcagctctcggcgatttacacgcagccaatcagatggaggagtttgct
gtggagtacaagatcatcaaccccaaggctatcacgatggggcagctgtatgggtgcttt
gaccaagtgagccacgagtggatggatggtgtccttgccaatgctttccgggagcaagcg
tcttcactctctgatgatcgcaagtggattatatttgatgggccagtggatgctatttgg
attgaaaatatgaacactgttctggatgacaataaaaagctgtgtctcatgagtggggaa
attatccagatgaactccaagatgagcctgatcttcgagcccgccgacctcgagcaagcc
tctccagccactgtgagcaggtgtgggatgatctacatggagccccatcaactaggctgg
aagcccctgaaggattcctacatggacaccctgccctccagtctcaccaaggagcacaaa
gaattggtcaatgacatgttcatgtggcttgtccagccctgcctggaatttggtcgcctt
cattgtaaatttgttgtccagacatctcccatccaccttgccttctcaatgatgagactg
tactcttctctgcttgatgaaatcagggcagtagaagaggaggaaatggaattaggtgaa
ggcctgtcaagtcaacagatctttctctggctccaaggactgtttctcttttccttggtg
tggaccgtggctggcaccatcaacgcagacagcagaaagaaatttgatgtgtttttccgc
aacctgatcatgggcatggatgataaccacccaaggcccaaaagcgtcaaactcaccaaa
aacaacatctttccagaaagaggaagcatctatgatttttattttatcaaacaagctagt
ggacattgggaaacgtggacacagtatatcaccaaagaggaggaaaaagttccagctggt
gcaaaggtctcagaactcatcatccccacaatggagacagcccggcagtccttcttcttg
aaaacctacttagaccatgagattccaatgctgttcgtgggtcccacaggcactggcaaa
tcagccatcaccaacaacttccttctccaccttcccaaaaatacgtacctacccaactgc
atcaatttctctgccagaacctcagccaatcagacccaggatatcatcatgtccaagctg
gatcgacgacggaagggccttttcgggcctcccatagggaagaaagcagtggtgtttgtg
gatgacctcaacatgccagccaaagaggtgtatggggcccagccacccatcgagctcctg
aggcagtggattgaccatggttactggtttgacaaaaaagacacaaccaggctggacatc
gtggacatgctgctcgtgacagccatggggccccccgggggaggaaggaatgacattact
ggacgattcactcgccatctgaatatcatttccatcaatgcctttgaggatgacatttta
accaagattttcagttcgattgttgactggcacttcgggaaagggtttgatgtgatgttt
ttaaggtacggaaagatgctggtccaagctactaagacaatttatagagatgcagtggag
aacttcttgccaactccctcgaagtcacattacgtctttaacctgcgggacttctcacga
gtgattcaaggggtcctgctgtgccctcacacacacctgcaggatgtagaaaaatgtatc
cggctttggatccatgaggtttatcgggtcttctatgatcgtctgattgacaaggaggac
agacaggtctttttcaacatggtgaaggaaaccacctccaattgcttcaagcagaccata
gagaaggtgcttatccacttgtcacccactggaaagatagtcgatgataacattcgaagc
ctcttctttggagattatttcaagccagaaagtgaccaaaaaatctacgatgagatcact
gacctgaaacagctgactgtggtcatggagcactatctggaagaattcaacaacatcagc
aaggcccccatgtccctggtcatgttcaggtttgccattgagcacatctctaggatctgc
cgtgtcctgaagcaggacaaaggccacctgctcctggtgggcatagggggcagcgggcgg
caaagtgccgccaaactgtccacattcatgaacgcatacgagctataccagattgagatc
accaagaactacgcaggcaatgactggcgagaagatcttaagaagatcatactgcaggtc
ggtgtggccaccaagagcaccgtgttcctcttcgccgacaaccagatcaaggatgaatca
ttcgtggaggacatcaacatgcttctgaacacaggtgacgtgcctaacatcttccctgct
gacgagaaggctgacatcgtggagaagatgcagactgcagccaggacccaaggagagaag
gttgaagtcactcctctttctatgtataacttctttattgagagggtaattaacaaaatc
tccttttcattagccatgagtccaataggggatgccttcaggaaccgcctgcggatgttc
ccttcgctgatcaattgctgtacgattgattggttccagtcctggcccacagatgcccta
gagttggtggctaacaaatttctagaggatgtggagcttgatgacaacattcgggtagag
gtcgtgtccatgtgcaaatatttccaagagagcgtcaagaagctgtcactcgattattac
aacaaacttcgaagacacaactatgttacccccacctcctaccttgaattgattctaacc
ttcaagacgctcctgaatagcaagaggcaagaggtggctatgatgaggaaccgctacctg
acaggcttgcagaaactcgactttgcagcttctcaggtagcggttatgcaaagagaactg
acagctcttcaacctcaactcatcctcacctccgaggaaactgccaagatgatggtgaaa
attgaagcggagacgagagaagctgatggaaagaaacttctggtgcaggcagatgaaaaa
gaagccaatgttgctgctgccattgcccaaggaatcaagaacgaatgtgagggggaccta
gctgaggcaatgcctgcactcgaggctgcactagctgctctggacaccctgaacccggcc
gacatctcgctggtgaagtcgatgcagaacccaccaggccctgtcaaactggtcatggag
agcatctgcatcatgaaagggatgaagccagagaggaagccagaccccagtggctccggt
aagatgatagaagattactggggggtatccaaaaagattcttggggatctgaaattcttg
gagagtcttaagacatatgacaaagacaacatccccccactgaccatgaagcggatccgg
gaaaggtttatcaatcacccggaattccagccagctgtcattaaaaatgtatcgtcggcc
tgcgagggtctgtgcaagtgggtgagggccatggaggtgtacgatcgcgtggccaaggtg
gtggctcccaaacgggagcgactgagggaggcagaggggaagctggctgcacagatgcag
aagctgaaccagaaaagagcagagctgaagctggtggtagatcggctccaggccctgaat
gacgactttgaagagatgaacaccaagaaaaaggacttggaggaaaacattgaaatctgc
tcccaaaagctggtcagggcagagaaactgatcagtggtcttgggggagagaaggacaga
tggaccgaagctgcccgacagctggggatccgctatactaatctgactggtgacgtgttg
ctgtcctcaggaactgtggcttacctgggcgcttttacagtggattatcgggtccagtgc
caaaatcagtggttggctgaatgtaaggacaaggtcatccctggcttcagtgacttcagt
ctcagccacacgttaggggatcccataaaaatccgtgcctggcagattgctgggcttccc
gttgactccttctccatcgacaatggcatcattgtatccaattccagacgctgggcctta
atgattgaccctcacgggcaggccaataaatggattaagaacatggagaaggcgaataaa
ctggctgtcatcaagttctctgatagcaactacatgaggatgctggaaaacgcgctgcag
ttaggcacccctgtcttgattgaaaacattggagaagagctggatgcttctatcgaacct
atcttgctcaaggcaacattcaaacagcaaggagttgagtacatgaggctgggtgaaaac
atcattgaatattccagggattttaagttatacatcacaacccgtttgaggaatccacat
tacctcccagaagttgccgtgaaggtctgtctcctcaacttcatgatcacccccttgggt
ctccaagatcaactccttggcatcgtggctgcgaaggagaagccagagctggaagagaaa
aagaaccagttgattgtggaaagtgccaagaacaagaagcatctcaaggaaattgaagat
aagatcttggaggttctctccatgtccaagggtaacatcctggaggatgaaaccgccatc
aaagttctgtcctcctccaaagtgctatctgaagagatctcagagaaacagaaagttgct
tccatgacagaaacgcagattgacgagactcggatgggctacaagccagtggctgtgcat
tctgccaccatcttcttttgtatctcggacctggccaacatcgagccgatgtaccagtac
tccctgacttggttcataaatctctacatgcattccttgacccacagcacgaagagcgag
gaactgaatctgcgcatcaagtacatcattgaccatttcaccctgagcatctacaacaac
gtgtgccgttctctgtttgagaaggacaagctactcttctctctcctcctgaccatcggc
atcatgaaacagaagaaggaaattacggaggaggtgtggtacttccttctcactggaggc
atcgcactggataacccctaccccaatccagctccccaatggctgtctgagaaggcatgg
gcagagattgtccgtgcatctgccttacccaaactgcatggcctgatggagcatttggaa
cagaacctgggtgaatggaagctgatctatgactcggcctggccccatgaggagcaactc
cctgggtcttggaagttctctcaaggattggagaagatggtgatccttcgatgtttgcgg
cctgacaaaatggtgccagcggtccgggagttcattgctgaacatatgggaaagctgtat
atcgaagcccctacgttcgatctccagggatcctacaatgattccagctgctgtgcgcct
ttgatttttgtgttgtctccaagtgcagacccaatggcaggcctgctgaagtttgctgat
gatcttggtatgggaggtaccagaacacagaccatctcccttggccaaggccaaggccct
attgctgccaaaatgatcaacaatgccatcaaagacgggacctgggtggtcttacagaac
tgccacctggccgcaagctggatgcctaccctggagaagatttgtgaggaggtgattgtt
cctgagagcaccaatgccagattcagactctggctaaccagctatccatcagagaagttt
ccagtcagcattctccagaatggaatcaaaatgaccaatgagccccccaaagggctccgg
gccaacctgttgcgctcctacctcaatgaccccatctcagatcctgtgttcttccaaagc
tgtgcaaaggcggtgatgtggcaaaagatgttatttggcctttgtttcttccacgccgtt
gttcaagagagaagaaacttcggccccctagggtggaatattccctatgaattcaacgaa
tctgacctgaggattagtatgtggcagatccagatgtttctcaatgactacaaggaggtg
ccctttgatgctctgacctacctgacaggggaatgtaattacggaggcagagtgactgat
gacaaagaccggcgtctcctgctgtcacttctgtccatgttctactgtaaggaaattgag
gaggactattactccctcgctcctggagacacttactacatccctcctcatggctcctac
cagtcctatatcgactatctcaggaatctccccatcacagcccacccagaagtgttcggc
ctccatgagaacgcagacatcaccaaagacaaccaggaaaccaaccagctgtttgagggg
gtcctgctgaccctccctagacagtcaggaggaagtggcaagtcccctcaggaagtggtt
gaggagttggcacaagacattctctccaagcttcccagagactttgacctggaagaggtc
atgaagttgtaccccgtggtctatgaagaatccatgaataccgtcctaaggcaggagctc
atcagattcaacaggctgaccaaagtggttcggaggagcctcatcaatcttggccgagcc
atcaaaggacaggtcctgatgtcctcggagctagaggaagtctttaacagcatgcttgtg
ggtaaagtgccagccatgtgggcagccaagtcttacccatcactgaagcctctggggggc
tacgtggctgacctgctggcccgcctgaccttcttccaggaatggattgacaaggggccc
cctgtggtattttggatctctggattctacttcacacagtcttttttgactggcgtctct
caaaattatgcccggaaatataccatccccattgaccacattggatttgagtttgaggta
accccacaagaaacagtgatggagaataaccccgaagatggggcctacatcaaagggctc
ttcttagaaggtgcccgttgggacaggaaaacgatgcagattggggaatctctccccaaa
atcctctatgacccactgcccatcatttggctgaaacctggggagagcgcaatgtttctg
catcaggacatctatgtgtgtccagtctacaaaacaagtgcccgcagaggaaccctctcc
accacaggccactctaccaactatgtcctctccattgagcttccaacagacatgccccag
aagcactggataaaccgaggggtggcctcactgtgccagctggataactga

KEGG   Homo sapiens (human): 56171Help
Entry
56171             CDS       T01001                                 

Gene name
DNAH7
Definition
(RefSeq) dynein axonemal heavy chain 7
  KO
K10408  dynein heavy chain, axonemal
Organism
hsa  Homo sapiens (human)
Pathway
hsa05016  Huntington disease
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09164 Neurodegenerative disease
   05016 Huntington disease
    56171 (DNAH7)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    56171 (DNAH7)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    Dyneins
     56171 (DNAH7)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: AAA_6 DHC_N2 Dynein_C AAA_8 AAA_9 AAA_7 AAA_lid_11 MT Dynein_heavy Dynein_AAA_lid AAA_5 AAA_lid_1 EF-hand_6 EF-hand_1 EF-hand_7 AAA_18 EF-hand_5 T2SSE
Motif
Other DBs
NCBI-GeneID: 56171
NCBI-ProteinID: NP_061720
OMIM: 610061
HGNC: 18661
Ensembl: ENSG00000118997
Vega: OTTHUMG00000154438
Pharos: Q8WXX0(Tbio)
UniProt: Q8WXX0
Position
2q32.3
AA seq 4024 aa AA seqDB search
MSSEQDKSASKEKSKKPVRFLPQLSMEKLASKEKFKAPARALPQLSMVSTKPHWQQAAPS
FHLSVKQDDESPEPFSVKNEQSHAEYMERFGKKGKLPHQVDDSYVGPSTSKSKGKSPHKE
RENFRSTLVNVIMQQDADLDSAVPDGSTIPKPTASAIEKDILRYYYYIHHGIDTDHVAPM
EDSWLEHVLDLVPQHLKVFTDSIVTLSDEMREDYLLSVRKSIVDFVLKDPREKGDDKKTD
ELPAHRAEMEILPKPWRKSFLAASSYIRDHLNAMNPTMLAVLDLWHTNFKKLRLVDIKEF
HNCQDALELSSFQNIIMRHMDSAKETLLKMWFPEVQNIYYQGNKKKQLPTGDSSAKLESF
FNCAAALMTLQLQDLTLVSMQDFTDLIAQPPDSVRAFEHPGFIMRLILDNDTIKFEPELS
DYIDIFLNVYDVMIKAVSFVPRVETKLYSKWESKSKPTTLKPIILNEIVDAHKEKIKEVI
MKESVAPTEHLRLYDKYDFLITRKAERDVDNFLAENHSYEKIIDEICKYQKLIEEIQYTS
IKTIRLGMFEMHCEELIRALVKRADIICGKLLAKMFRDHQEVNTRLCDEFERIAEKALST
PPNTAELMEMKAYIQKVEVTDMIELEQRLVDSKNCLAFLIEYVNFSPADMRLNNSVFQWY
GRMGEIFEEHRKIIKEKIEQYQEGLKLRCERFVEELESYAKQSEEFYSFGDLQDVQRYLK
KAQILNGKLDLAADKIEQFNAEEEAFGWLPSVYPQRKKIQDGLNPYLRLYETAVEFSSNY
RAWTEGPYHKVNPDQVEADIGNYWRGLYKLEKTFHDSPYALAMTKKVRSKVEDFKQHIPL
IQVICNPGLRPRHWEAMSAIVGYPLQPSDDSTVSSFLDMNLEPYIDRFEGISEAASKEYS
LEKAMEKMITEWDAVEFVIHSYRETGTFILASVDEIQMLLDDHIIKTQTMRGSPFIKPYE
KQMREWEGKLLLLQEILDEWLKVQATWLYLEPIFSSPDIMSQMPEEGRRFTAVDKTWRDI
MRSVMQDKHVLTVVTIDRMLERLKKSNELLELILKGLNEYLEKKRLFFPRFFFLSNDELL
EILSETKDPTRVQPHLKKCFEGIAKVEFTETLDITHMKSSEGEVVELIEIISTAKARGQV
EKWLVELERVMINSIHKVTGDATFAYTKYERINWVRDWPGQTVLCVSQIFWTKEVQTAIP
MGIKALEQYLKTCNRQIDDIVTLVRGKLSMQNRVTLGALVVLDVHARDVLSSLVKKNISD
DSDFEWLSQLRYYWQENHLETKMINAGLRYGYEYLGNSPRLVITPLTDRCYRTLFGALHL
HLGGAPEGPAGTGKTETTKDLAKAVAKQCVVFNCSDGLDYLALGKFFKGLLSCGAWACFD
EFNRIDLEVLSVVAQQILTIQRGINAGADILMFEGTELKLDPTCAVFITMNPGYAGRSEL
PDNLKALFRTVAMMVPDYAMIAEIVLYSCGFVTARPLSVKIVATYRLCSEQLSSQHHYDY
GMRAVKSVLTAAGNLKLKYPNENEEILLLRSIIDVNLPKFLSHDLPLFEGITSDLFPGVK
LPKPDYNDLLAAIKDNCASMNLQMTAFFSEKILQVYEMMIVRHGFMIVGEPFGGKTSAYR
VLAGALNDICEKGLMEENKVQITVLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSFRAFAS
SVTPDRKWLIFDGPVDAVWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMDLEVAS
PATVSRCGMIYMEPHMLGWRPLMLSWVNLLPASVSVIQKEFIMGLFDRMVPVSVEFIRKH
TKELSPTSDTNLVRSLMNLIDCFMDDFADEVKLKERNDRETYSLLEGIFLFSLIWSVGAS
CTDDDRLKFNKILRELMESPISDRTRNTFKLQSGTEQTSSKALTVPFPEKGTIYDYQFVT
EGIGKWEPWIKKLKEAPPIPKDVMFNEIIVPTLDTIRYSALMELLTTHQKPSIFVGPTGT
GKSVYITNFLLNQLNKEIYKPLLINFSAQTTAAQTQNIVMSKLDKRRKGVFGPPLGKRMV
VFVDDVNMPAREVYGAQPPIELLRQWLDHWNWYDLKDCSMIKLVDIQIMCAMGPPGGGRN
PVTPRYMRHFNIITINEFSDKSMYTIFSRILTWHLEICYKFPDEFLDLTTQIVNGTMTLY
KEAMKNLLPTPAKSHYLFNLRDFSRVIQGVCLSRPETTETTEVIKRLWVHEVLRVYYDRL
LDNTDRSWLINYIQEILRNYMYEDFHELFQRLDFDNDGMVEADDLRSLMFCDFHDPKRED
TNYREIADVDNLRMIVEIHLEEYNNISKKPMNLVLFRFAIEHISRISRILKQPRSHALLV
GVGGSGRQSVTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRKCAEGEMQGVFLFTD
TQIKEESFLEDVSNLLNAGEIPNLFALDEKQEICDKMRQLDRQRDKTKQTDGSPIALFNM
FIDHCRSQLHVVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQSWPEDALQAVASRFLEEI
EMSEEIRDGCIDMCKSFHTSTIDLSKSFFVELQRYNYVTPTSYLELISTFKLLLEKKRSE
VMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLKVASKEVDEMMIMIEKESVEVAKT
EKIVKADETIANEQAMASKAIKDECDADLAGALPILESALAALDTLTAQDITVVKSMKSP
PAGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWGPAKRLLGDMRFLQSLHEYDKDNI
PPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYDKVAKIVAPKKIKLAAA
EGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADLENQVDLCSKKLERAEQLI
GGLGGEKTRWSHTALELGQLYINLTGDILISSGVVAYLGAFTSTYRQNQTKEWTTLCKGR
DIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGIIIMNARRWPLMIDPQSQANKW
IKNMEKANSLYVIKLSEPDYVRTLENCIQFGTPVLLENVGEELDPILEPLLLKQTFKQGG
STCIRLGDSTIEYAPDFRFYITTKLRNPHYLPETSVKVTLLNFMITPEGMQDQLLGIVVA
QERPDLEEEKQALILQGAENKRQLKEIEDKILEVLSSSEGNILEDETAIKILSSSKALAN
EISQKQEVAEETEKKIDTTRMGYRPIAIHSSILFFSLADLANIEPMYQYSLTWFINLFIL
SIENSEKSEILAKRLQILKDHFTYSLYVNVCRSLFEKDKLLFSFCLTINLLLHERAINKA
EWRFLLTGGIGLDNPYANLCTWLPQKSWDEICRLDDLPAFKTIRREFMRLKDGWKKVYDS
LEPHHEVFPEEWEDKANEFQRMLIIRCLRPDKVIPMLQEFIINRLGRAFIEPPPFDLAKA
FGDSNCCAPLIFVLSPGADPMAALLKFADDQGYGGSKLSSLSLGQGQGPIAMKMLEKAVK
EGTWVVLQNCHLATSWMPTLEKVCEELSPESTHPDFRMWLTSYPSPNFPVSVLQNGVKMT
NEAPKGLRANIIRSYLMDPISDPEFFGSCKKPEEFKKLLYGLCFFHALVQERRKFGPLGW
NIPYEFNETDLRISVQQLHMFLNQYEELPYEALRYMTGECNYGGRVTDDWDRRTLRSILN
KFFNPELVENSDYKFDSSGIYFVPPSGDHKSYIEYTKTLPLTPAPEIFGMNANADITKDQ
SETQLLFDNILLTQSRSAGAGAKSSDEVVNEVASDILGKLPNNFDIEAAMRRYPTTYTQS
MNTVLVQEMGRFNKLLKTIRDSCVNIQKAIKGLAVMSTDLEEVVSSILNVKIPEMWMGKS
YPSLKPLGSYVNDFLARLKFLQQWYEVGPPPVFWLSGFFFTQAFLTGAQQNYARKYTIPI
DLLGFDYEVMEDKEYKHPPEDGVFIHGLFLDGASWNRKIKKLAESHPKILYDTVPVMWLK
PCKRADIPKRPSYVAPLYKTSERRGVLSTTGHSTNFVIAMTLPSDQPKEHWIGRGVALLC
QLNS
NT seq 12075 nt NT seq  +upstreamnt  +downstreamnt
atgagcagtgagcaggataaatcggccagcaaagaaaaatccaagaaaccagtaagattt
ctaccacagctgtctatggagaaattagccagcaaagaaaagttcaaggcaccagcaaga
gctttaccacagctgtctatggtgagtacaaagccccactggcagcaggcagctccatca
ttccatttgagtgtaaagcaggatgatgagagtccagaaccatttagtgttaaaaatgaa
cagtcccatgctgaatacatggaacgttttggaaaaaagggcaaattaccccaccaagtt
gatgatagttatgttggaccatctacttccaaatcaaagggcaaatctccacataaagaa
cgagaaaactttagaagtactcttgttaatgtcattatgcaacaagatgctgacttagac
tcagctgtccctgatggaagcacaattccaaaaccgaccgcttctgctatagagaaagac
atcttgagatattactattatattcaccatggaattgatacagaccatgtagccccaatg
gaagattcttggctagaacacgtactggatttagttccacaacatctgaaagtcttcact
gacagcatagttacattatctgatgaaatgagagaggattatcttcttagtgtaaggaaa
tccatagttgattttgttttaaaagatcctcgagagaaaggagatgataagaagacagat
gaacttccagcccatcgtgctgaaatggaaattctgccaaaaccttggaggaaatctttt
ttagctgcaagcagttatattagggatcacttgaatgcaatgaaccccacaatgctggct
gtactagatttgtggcacactaattttaaaaaattacgtttagttgatatcaaagaattt
cataattgccaggatgcattagagctgtcaagttttcagaacattatcatgagacacatg
gactctgccaaagagactctacttaaaatgtggtttccagaagtgcagaatatttattac
caaggtaataaaaaaaagcaattgccaactggtgacagcagtgccaaattggaatctttt
ttcaactgtgctgctgcacttatgactttacagctgcaggacctcactttagtctccatg
caagatttcacggacttaattgcacaacccccagattctgttagagcttttgaacatcca
ggtttcatcatgaggctgattcttgataatgacaccattaagtttgaacctgagttgagt
gactatatagatatctttctaaatgtttatgacgtcatgattaaagctgtcagttttgtg
ccaagagttgagacaaaattgtattccaagtgggaaagtaagtctaaaccaacaaccttg
aagcccataattctgaatgaaattgtagatgctcacaaagaaaagatcaaggaagttatt
atgaaagagagtgtggcacctactgagcacctcagactctatgacaagtatgacttttta
attaccagaaaagctgagcgagatgttgataacttcctcgcagaaaatcatagttatgaa
aaaataatagatgaaatttgcaaataccagaaactaatagaggaaatacagtacacatcc
ataaagactattcgtttaggaatgtttgaaatgcactgtgaggaattaatcagagctttg
gtgaagcgagcagatattatttgtgggaaacttctagctaaaatgttcagagatcatcag
gaagtaaatacaagattatgcgatgaatttgagaggatagctgaaaaagctcttagcact
cctccaaatacagcagaactaatggaaatgaaggcttacattcagaaagtggaggtaact
gatatgattgaactagaacagagattagtggattccaaaaactgcctcgccttcctcatc
gagtatgtcaacttttctccagcagacatgaggctaaataatagtgttttccagtggtat
ggaaggatgggagaaatttttgaagaacacaggaaaatcattaaagagaaaatagaacaa
tatcaagaaggtctgaagttacggtgtgaacggtttgtggaggaattggagagttatgct
aagcaatcagaagaattttattcatttggagatcttcaggatgttcagcggtacctaaaa
aaggctcaaatactgaatggaaagttggatttagctgcagataagattgagcagtttaat
gctgaagaggaagcatttggttggctaccatctgtatatcctcaacgtaaaaaaatccaa
gatggcttgaacccttatcttcgtctttatgaaactgctgtcgaatttagcagcaactat
agagcatggacagaagggccatatcataaagtgaatccagaccaagtagaagcagatatt
ggaaattactggagaggattatataaactggagaaaacctttcatgattctccatatgca
ttggcaatgacaaaaaaagtaagatcaaaggtggaagatttcaagcagcacattcctctc
attcaagtgatctgtaatcctggtttgcgccccaggcactgggaggccatgtctgccatt
gttggttaccctttgcagccatcagatgactccacagtctcctcttttttagacatgaat
ctggaaccatatatagaccgatttgaaggtattagtgaagcagctagcaaagaatattct
cttgaaaaggcgatggagaagatgattactgagtgggatgcagtggaatttgtcatccat
tcttatagagaaactgggacatttattttggcatcagttgatgaaattcagatgttgttg
gatgaccatattattaaaacacaaactatgcgaggatctcctttcattaagccttatgaa
aaacaaatgagagaatgggagggcaagctcctactgcttcaggagattctggatgaatgg
ctcaaagtccaagccacgtggctgtatctggagcccattttcagctctccagacattatg
tctcaaatgcctgaggaaggcagacgatttacagctgtggataagacatggagagatata
atgagaagtgtcatgcaggataaacatgttctgacagttgtaaccattgacagaatgctg
gaaaggctgaaaaaatctaatgaacttttggagctcattcttaaaggacttaatgaatat
ttggaaaagaaacgcctctttttccccagattcttttttttgtccaatgatgaacttctt
gagatactatctgagactaaagatcccactagggtgcaacctcacttgaagaaatgtttt
gaaggaatcgcaaaggtagaatttacggaaactttagacattactcacatgaagagcagc
gaaggagaggttgtagaactcatagagattatttcaacagccaaagccagaggtcaagtg
gagaagtggttggttgaattagagagagttatgattaactccatccacaaggtaactgga
gatgcaacttttgcctatacaaaatatgaacgaattaactgggtaagggattggcctgga
cagactgttctctgtgtatcccaaatcttttggacaaaagaagtacaaacagctattcca
atggggataaaggctcttgagcaatacttgaaaacatgtaacagacaaattgatgatatt
gtcactttggtgcgtggcaaattgtccatgcagaatcgcgtaactctgggagcacttgtg
gtactggatgtccatgctagagatgtcctctcatcacttgtaaaaaaaaatattagcgat
gactctgactttgaatggttaagtcagcttaggtactactggcaagaaaatcatttagaa
acaaaaatgatcaatgctggtttgcgatatggatatgaatatctgggtaattcccctagg
ctggttattacaccactcacggatagatgttacagaaccttatttggagcccttcatttg
caccttggaggagcacctgagggtccagctggcactgggaagactgaaactaccaaggat
ttggcaaaagctgtagccaaacaatgtgttgttttcaactgctctgatgggttggattat
ttggctttgggaaaattctttaagggactgttatcttgtggagcctgggcttgctttgat
gagtttaacagaattgatttggaagtactctctgtggttgctcaacaaatccttactatc
caaagaggtattaatgcaggtgctgatatactgatgtttgaaggaactgaactaaaactt
gaccccacatgtgctgtctttataacaatgaaccctgggtatgctgggcgatcagaactg
ccagataacctgaaggctctctttcggacagtagcaatgatggtacctgactatgccatg
attgctgaaatagtcctatactcctgtgggtttgtcactgctcgaccactgtctgtaaaa
attgtggctacgtatcgcttgtgttcagagcagctgtcatctcaacatcactacgactat
ggaatgagagccgtgaagtcagttcttactgctgctgggaatctgaagctgaaatatcca
aatgaaaatgaagaaattttgctgcttagatctatcattgatgtaaatctgccaaaattt
ttatcccatgatttaccactctttgagggaattacttcggatttgtttcctggggtaaaa
ttaccaaaaccagattacaatgatttgctggcagctatcaaagacaattgtgcctccatg
aatttgcaaatgactgcattcttttccgagaagattcttcaagtatatgaaatgatgatt
gtgcgtcatggttttatgattgttggagaaccatttggaggaaaaactagtgcatatcgt
gtcttagctggagcactaaatgatatatgtgaaaaggggctaatggaagaaaacaaagtt
caaataactgttttaaatcctaagtctgtcaccatgggccaactgtacggacagtttgat
tcagtgtcccatgaatggtctgatggggtccttgctgtcagttttagagcatttgcctct
tcagtgactccagataggaaatggttaatttttgatggcccagtagatgcagtgtggatt
gagaatatgaacactgtgctggatgacaacaagaagctatgtctgatgagtggggagatt
attcagatgtcaccacaaatgaatctaatttttgagccaatggatttagaagttgcttcc
cctgccactgtttccagatgtggcatgatttacatggagcctcacatgttaggctggaga
ccactgatgttgtcctgggtgaatctgttacctgcgtcagtcagtgttattcaaaaggaa
ttcataatgggcttatttgacagaatggtccctgtttcggttgaatttattagaaagcat
acaaaggaattatctcctacttccgatacaaacttggtccggtccttaatgaatctaata
gactgttttatggatgattttgctgatgaagtcaaactaaaggagagaaatgatcgagaa
acttactctttgcttgagggcatttttctgttttcattgatctggtccgttggtgcttct
tgtacagatgatgatcgattgaaatttaataagattcttcgagaactaatggaaagtcca
atttcagatcgaactcgaaatacgtttaaattacagagtggtactgagcaaacatcctca
aaggcactaactgtcccatttcctgaaaaaggaacaatttatgattatcaatttgtcact
gagggaataggaaaatgggaaccatggataaagaaattgaaagaagctcctccaattcct
aaagatgtaatgtttaatgaaatcattgtgccaactctggacacaattcgatactctgca
ttaatggaattgctgaccacccatcaaaagccttcaatatttgtaggaccaacaggaact
gggaaaagtgtttacattacgaattttcttttaaatcaactaaataaggaaatctacaaa
cctctgctaattaacttctcagcacaaactacagcagctcaaactcagaatattgtcatg
tcaaaattggacaagagaagaaagggagtttttggtcctcctttgggcaagagaatggtt
gtctttgtagatgatgtcaatatgcctgctcgggaggtatatggggctcaacctcccatt
gagttacttagacagtggttagaccactggaactggtatgatctaaaagattgttccatg
attaaactagtggacattcagatcatgtgtgctatgggacctccaggtggtggtcgaaat
ccagtaactcctcgatacatgcgacatttcaatattataacaatcaatgagtttagtgat
aaatccatgtatacaatcttctctagaatcttaacttggcatttagaaatctgttataaa
tttccagatgaatttctagatttgaccacacaaatcgtaaatggcacaatgactctgtat
aaagaagcaatgaagaatctcttgcctactccagctaaatctcactacttgttcaacctc
cgtgatttctcccgtgtcattcaaggtgtttgtttgtcaagaccagaaacaacagaaacc
acagaagtgattaaacgtctttgggttcatgaggtccttcgagtgtattatgaccgcctt
ctggacaatacagacagaagctggctcatcaactacattcaagaaattttgagaaactac
atgtatgaagattttcatgagctttttcagcgtttggattttgataatgatggcatggtg
gaagcagatgacttacgcagcttaatgttttgtgatttccatgatcccaagagggaggat
accaactacagagaaatcgcagatgtggataatcttcgaatgatagtagaaattcaccta
gaagaatacaacaatataagcaaaaaacccatgaaccttgtcttgtttcgatttgccata
gagcacatcagcagaatttccaggatcctgaagcagcctcgcagccatgctctcctagta
ggggttggagggagtggaaggcagtctgtcaccagattagctgcccacatggctgattat
tcagttttccaagttgaaatctctaaggggtatgatactactgaatggcatgaagattta
aaagtgatcttaaggaaatgtgcggaaggtgagatgcagggtgtcttcctgtttacagat
actcaaattaaagaagagtcttttctggaagatgtcagtaatctgctaaatgctggggag
attccaaatctctttgcattagatgagaagcaagagatatgtgataagatgcgtcagtta
gatcgccagcgggataaaaccaagcaaacagatggcagccccatagcccttttcaacatg
tttattgatcattgccgcagccaactgcatgtggtccttgccatgagtcccattggagat
gcatttcggaatcgtcttagaaagttccctgctcttgttaactgctgtaccattgactgg
tttcagtcatggcctgaagatgcactccaggcagttgcctcacgattcttggaagaaatt
gaaatgtcagaggaaatacgagatggctgtatcgacatgtgtaaaagcttccacacttct
actatagatttatccaaatctttctttgttgaacttcaaagatacaattatgtgactcct
acctcttacctcgaattaatctccaccttcaaactgttgttagaaaagaaaagaagtgaa
gtaatgaaaatgaaaaagagatatgaagtgggtttggagaaactggattctgcttcatct
caagtagccacaatgcagatggagttggaggcactacatcctcaattaaaagttgctagc
aaagaggttgatgaaatgatgataatgattgagaaagagtctgtagaagttgccaaaact
gaaaaaatagtgaaagctgatgaaacaatagcgaatgaacaagctatggcttccaaagcc
atcaaagatgagtgcgatgctgacctggcaggtgccttgccaatattagagtcagcactg
gccgcccttgatactcttactgcacaggatattacagtggtaaaatccatgaagagtcct
cctgctggtgtcaagcttgttatggaagctatatgcatcttgaaaggaatcaaagctgac
aaaatccctgacccaacaggttcagggaaaaaaattgaggatttctggggcccagctaag
agacttcttggtgacatgaggtttctgcagtcacttcatgaatatgacaaggacaatatt
cctccagcttatatgaatatcataagaaaaaattatattccaaatccagattttgtacca
gaaaaaatcagaaatgcttctacagcggccgaaggtctgtgcaaatgggtcatagcaatg
gattcatatgataaagtggcaaaaatagtagctcccaaaaagataaaactggctgcagct
gaaggggagcttaaaattgccatggatggtcttagaaagaagcaggcagcccttaaggaa
gttcaggacaagctggccaggcttcaagacacacttgaattaaataaacaaaagaaggct
gacctggaaaaccaggttgacctttgcagcaaaaaactagaacgagctgaacagttgatt
ggaggccttggaggtgagaaaactcgatggagccacacagctctggagctaggtcagctg
tacatcaacttgactggggatatcctcatttcctccggagtggttgcttacctcggagcc
ttcacatccacctatagacagaatcaaactaaagagtggacaactttgtgcaaaggaaga
gatatcccctgctcagatgattgctctcttatgggtaccctgggagaagctgtgacaatt
cgaacttggaatattgctggattaccttctgactcattttccattgataatgggataatc
ataatgaatgcaagaaggtggcctctgatgatagatcctcaaagtcaggctaataaatgg
atcaagaacatggaaaaagccaatagtctttatgtgattaaacttagtgaacctgactat
gtcaggactctggaaaattgcatccagtttggtactcctgtgttgctagaaaatgttggc
gaagaactagatcctattttggaacctcttctactaaaacaaacctttaagcagggtggg
agtacatgtatccggcttggggactccacaattgaatatgcacctgacttccgcttctat
attactaccaagttaagaaatcctcattatcttcctgaaacatcagtaaaggtaacatta
ttaaacttcatgataacccctgagggaatgcaagatcagcttctgggaattgtggtggca
caagaaaggccagaccttgaagaagaaaagcaagccttgatattacaaggagctgaaaat
aaaaggcagttaaaagaaatagaagacaagattttagaagttctttcatcttcggaaggc
aatatattagaagatgaaactgctattaagatattatcttcctccaaggccttggctaat
gagatttctcagaagcaggaagtagccgaagagacagagaaaaagattgacaccacccgc
atgggctatcgtcctattgccatccattcttccatcctatttttttctcttgctgattta
gccaacattgagcccatgtaccagtattcactgacctggtttattaaccttttcatcctg
tctattgaaaattcagagaaatcagaaattttggcaaaaaggcttcagattctcaaggat
cactttacttattcactgtatgttaatgtctgccggtcactctttgaaaaggataagctg
ctcttttccttttgtctaaccataaatctactgctgcatgagcgggcgattaataaagct
gagtggagatttctgctaactggtggcattggactggataatccttatgccaacctttgt
acatggcttcctcagaaatcctgggatgaaatatgtcgattagatgatttgcctgccttc
aaaaccattcgtagagagtttatgcgcttaaaggatggatggaagaaagtatatgatagt
ttggaaccacaccatgaggttttccctgaagaatgggaagataaagcaaatgagtttcaa
aggatgcttattattcgttgcttgaggccagacaaggttattccaatgttgcaggaattt
ataatcaacagattgggacgtgcattcattgaaccacccccctttgatttagccaaggca
tttggagacagtaactgctgtgcaccactgattttcgtgctctctcctggagcagatccc
atggctgcccttctaaaatttgctgatgaccagggatatgggggatcaaaacttagctct
ttatctcttggtcaaggccaagggcccattgctatgaagatgttagaaaaagctgtcaag
gaaggaacatgggttgttcttcagaattgtcaccttgccacctcttggatgccaaccctt
gagaaagtctgtgaggagttaagcccagagtcaacacatccagatttccgaatgtggcta
acgagttacccatctccaaatttccctgtgtcagtactgcagaatggagtgaaaatgacc
aatgaagcaccaaaaggtttacgggctaatatcattcgatcatacctcatggacccgatc
tctgatccggagttctttggcagctgcaaaaagcctgaggaattcaagaaattgctttat
ggcctgtgtttctttcatgctttggtacaagaaagacggaaatttggacccctagggtgg
aatattccttatgagttcaatgagacagatctgagaatcagcgtacagcagctccacatg
ttcctgaaccagtatgaggaactgccgtatgaggctctgcggtacatgactggcgaatgc
aattacggaggcagagtgaccgatgactgggaccggcgcacgctgcgcagcattctaaac
aaattcttcaatcccgaattagttgaaaattcagactataagttcgactcaagtggcatc
tattttgttcctccttctggtgatcacaaaagctacatcgaatacacaaagactctgcca
ctgaccccagcaccagaaatctttgggatgaatgccaatgcagatatcactaaggatcag
tcagaaactcagctgctatttgataacattcttcttacacagtctcgttcagcaggtgct
ggtgcaaaatcatcagatgaagtagtgaatgaggtcgctagtgacatcttgggcaaactt
ccaaacaacttcgacatcgaggctgccatgaggaggtacccaacaacttatactcagagc
atgaacactgtacttgtccaagagatgggacggttcaataagttactgaagaccataaga
gattcgtgcgtaaatattcaaaaagcaatcaaggggcttgcagtcatgtctacagatctt
gaagaagtggttagcagcattttgaatgtcaaaattccagaaatgtggatgggtaaatcc
tacccaagccttaaaccacttggcagctatgtgaatgacttccttgcaagactaaaattc
ttgcagcaatggtatgaggttggtcctcctccagtcttctggctttctggcttcttcttc
acacaagccttcctgaccggtgcccagcagaactacgccaggaaatacacaattcctatt
gatcttcttgggtttgactatgaagtgatggaagacaaagaatacaagcatcctcctgag
gatggtgttttcattcacggattatttctggatggagcttcctggaatagaaagatcaag
aaacttgcagaatcgcatcccaaaattctttatgatacagtgcctgtgatgtggctaaag
ccctgtaagagggcagatataccaaaacggccaagttatgttgctccattgtataagaca
agtgagcggagaggagtattatccaccactggccattccacgaattttgtgattgccatg
actcttccctctgaccaacccaaggaacactggattggacgaggtgtagcactgttatgt
caacttaattcataa

KEGG   Homo sapiens (human): 64446Help
Entry
64446             CDS       T01001                                 

Gene name
DNAI2, CILD9, DIC2
Definition
(RefSeq) dynein axonemal intermediate chain 2
  KO
K11143  dynein intermediate chain 2, axonemal
Organism
hsa  Homo sapiens (human)
Pathway
hsa05016  Huntington disease
Disease
H00564  Primary ciliary dyskinesia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09164 Neurodegenerative disease
   05016 Huntington disease
    64446 (DNAI2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    64446 (DNAI2)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    Dyneins
     64446 (DNAI2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: WD40 DUF4795
Motif
Other DBs
NCBI-GeneID: 64446
NCBI-ProteinID: NP_075462
OMIM: 605483
HGNC: 18744
Ensembl: ENSG00000171595
Vega: OTTHUMG00000178578
Pharos: Q9GZS0(Tbio)
UniProt: Q9GZS0
Position
17q25.1
AA seq 605 aa AA seqDB search
MEIVYVYVKKRSEFGKQCNFSDRQAELNIDIMPNPELAEQFVERNPVDTGIQCSISMSEH
EANSERFEMETRGVNHVEGGWPKDVNPLELEQTIRFRKKVEKDENYVNAIMQLGSIMEHC
IKQNNAIDIYEEYFNDEEAMEVMEEDPSAKTINVFRDPQEIKRAATHLSWHPDGNRKLAV
AYSCLDFQRAPVGMSSDSYIWDLENPNKPELALKPSSPLVTLEFNPKDSHVLLGGCYNGQ
IACWDTRKGSLVAELSTIESSHRDPVYGTIWLQSKTGTECFSASTDGQVMWWDIRKMSEP
TEVVILDITKKEQLENALGAISLEFESTLPTKFMVGTEQGIVISCNRKAKTSAEKIVCTF
PGHHGPIYALQRNPFYPKNFLTVGDWTARIWSEDSRESSIMWTKYHMAYLTDAAWSPVRP
TVFFTTRMDGTLDIWDFMFEQCDPTLSLKVCDEALFCLRVQDNGCLIACGSQLGTTTLLE
VSPGLSTLQRNEKNVASSMFERETRREKILEARHREMRLKEKGKAEGRDEEQTDEELAVD
LEALVSKAEEEFFDIIFAELKKKEADAIKLTPVPQQPSPEEDQVVEEGEEAAGEEGDEEV
EEDLA
NT seq 1818 nt NT seq  +upstreamnt  +downstreamnt
atggagattgtgtacgtgtacgtcaagaagcgcagcgagttcgggaagcagtgcaatttc
tcggaccgccaggccgagctgaacatcgacatcatgcccaaccctgagctggccgagcag
ttcgtggagcggaacccagtggacacgggcatccagtgctcgatcagcatgtcggaacac
gaggccaactcagagcggtttgagatggagacccggggagttaaccatgtcgaggggggc
tggcccaaggacgtgaaccccctggagctggagcagaccatccgtttccggaagaaagtg
gagaaagatgagaactacgttaacgccatcatgcagctcggctctatcatggagcactgc
atcaagcagaacaatgccattgacatctatgaagagtatttcaatgacgaggaggccatg
gaagtgatggaggaggacccttcagctaaaaccatcaatgtgttcagggacccccaggaa
atcaagagggctgccacacacctctcctggcaccccgatggcaacaggaagttggcagtg
gcatactcctgcttggattttcagcgggcacctgtgggcatgagcagcgattcatacatc
tgggacctggaaaaccccaacaagcctgaacttgctctgaagccatcgtctccactcgtg
acgttggagttcaaccccaaagattcccacgtactcctgggtggctgctacaatggacag
atagcctgctgggacacccgaaagggcagcctggtggcggagctatccaccattgagtcc
agccaccgagaccctgtgtatggcaccatctggctgcagtcgaagacgggcaccgagtgc
ttctcagcttccacggatgggcaggtcatgtggtgggacatccgaaagatgagcgagccc
actgaagttgtgatcttggacatcaccaagaaggaacagttggaaaatgccttgggggcc
atctccctggagttcgaatctactttgcccaccaagttcatggtggggaccgagcagggc
atcgtcatctcctgcaaccgcaaggccaagacgtcagctgaaaagattgtgtgcaccttc
ccgggccatcatggccccatctacgccctccagagaaaccccttctacccgaagaacttc
ctgacggttggcgactggacagcccgcatttggtctgaagacagccgggaatcgtccatc
atgtggaccaagtaccacatggcttacctcactgatgctgcctggagccccgtgaggccg
accgttttctttaccaccaggatggacggaaccctggatatctgggacttcatgttcgag
cagtgcgatcccaccctcagcttgaaggtgtgtgacgaggccctcttctgcctccgggtg
caggacaatgggtgtctcatcgcctgcggctcccagctggggacaaccaccctgctggag
gtctcgcctgggctctctaccctccagaggaatgagaagaacgtagcctcttccatgttt
gagcgtgagacccggcgagagaagatcctggaggccaggcaccgggagatgcggctgaag
gagaagggtaaggcggagggcagggatgaggagcagaccgatgaggagctggccgtagac
ctggaggcgctggtcagcaaggccgaggaggagttcttcgacatcatcttcgcagagctg
aagaagaaggaggcagacgccataaagctgacgccagtgcctcagcaaccaagtccagaa
gaagaccaggtggtggaggagggagaggaagcagcgggggaagaaggggatgaagaagtg
gaagaagacttagcctag

KEGG   Homo sapiens (human): 7802Help
Entry
7802              CDS       T01001                                 

Gene name
DNALI1, P28, dJ423B22.5, hp28
Definition
(RefSeq) dynein axonemal light intermediate chain 1
  KO
K10410  dynein light intermediate chain, axonemal
Organism
hsa  Homo sapiens (human)
Pathway
hsa05016  Huntington disease
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09164 Neurodegenerative disease
   05016 Huntington disease
    7802 (DNALI1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    7802 (DNALI1)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    Dyneins
     7802 (DNALI1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Ax_dynein_light RIB43A DUF724 UPF0242 TSNAXIP1_N
Motif
Other DBs
NCBI-GeneID: 7802
NCBI-ProteinID: NP_003453
OMIM: 602135
HGNC: 14353
Ensembl: ENSG00000163879
Vega: OTTHUMG00000004222
Pharos: O14645(Tdark)
UniProt: O14645 A0A499FIY3
Position
1p34.3
AA seq 258 aa AA seqDB search
MIPPADSLLKYDTPVLVSRNTEKRSPKARLLKVSPQQPGPSGSAPQPPKTKLPSTPCVPD
PTKQAEEILNAILPPREWVEDTQLWIQQVSSTPSTRMDVVHLQEQLDLKLQQRQARETGI
CPVRRELYSQCFDELIREVTINCAERGLLLLRVRDEIRMTIAAYQTLYESSVAFGMRKAL
QAEQGKSDMERKIAELETEKRDLERQVNEQKAKCEATEKRESERRQVEEKKHNEEIQFLK
RTNQQLKAQLEGIIAPKK
NT seq 777 nt NT seq  +upstreamnt  +downstreamnt
atgattccgcccgcagactctttgctcaagtacgacaccccagtgctggtgagccggaac
acggagaaacggagccccaaggctcggctactgaaagtcagcccccagcagcctggacct
tcaggttcagccccacagccacccaagaccaagctcccctcaactccctgtgtcccagat
cctacaaagcaggcagaagaaatcttgaatgccatactacccccaagggagtgggtggaa
gacacgcagctatggatccagcaggtgtccagcacccctagcaccaggatggacgtggtg
cacctccaggagcagttagacttaaagctgcagcagcggcaggccagggaaacaggcatc
tgccctgtccgcagggaactctactcacagtgttttgatgagttgatccgggaggtcacc
atcaactgtgcggagagggggctgctgctgctgcgagtccgggacgagatccgcatgacc
atcgctgcctaccagaccctgtacgagagcagcgtggcgtttggcatgaggaaggcactg
caggctgagcaggggaagtcagacatggagaggaaaatcgcagaattggagacggaaaag
agagacctggagaggcaagtgaacgagcagaaggcaaaatgtgaagccactgagaagcgg
gagagcgagaggcggcaggtggaggagaagaagcacaatgaggagattcagttcctgaag
cgaacaaatcagcagctgaaggcccaactggaaggcattattgcaccaaagaagtga

KEGG   Homo sapiens (human): 83544Help
Entry
83544             CDS       T01001                                 

Gene name
DNAL1, C14orf168, CILD16, LC1
Definition
(RefSeq) dynein axonemal light chain 1
  KO
K10411  dynein light chain 1, axonemal
Organism
hsa  Homo sapiens (human)
Pathway
hsa05016  Huntington disease
Disease
H00564  Primary ciliary dyskinesia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09164 Neurodegenerative disease
   05016 Huntington disease
    83544 (DNAL1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    83544 (DNAL1)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    Dyneins
     83544 (DNAL1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: LRR_4 LRR_9 LRR_8
Motif
Other DBs
NCBI-GeneID: 83544
NCBI-ProteinID: NP_113615
OMIM: 610062
HGNC: 23247
Ensembl: ENSG00000119661
Vega: OTTHUMG00000171642
Pharos: Q4LDG9(Tbio)
UniProt: Q4LDG9
Position
14q24.3
AA seq 190 aa AA seqDB search
MAKATTIKEALARWEEKTGQRPSEAKEIKLYAQIPPIEKMDASLSMLANCEKLSLSTNCI
EKIANLNGLKNLRILSLGRNNIKNLNGLEAVGDTLEELWISYNFIEKLKGIHIMKKLKIL
YMSNNLVKDWAEFVKLAELPCLEDLVFVGNPLEEKHSAENNWIEEATKRVPKLKKLDGTP
VIKGDEEEDN
NT seq 573 nt NT seq  +upstreamnt  +downstreamnt
atggcgaaagcaacaacaatcaaagaagccttagcgagatgggaagagaaaactggccag
aggccatctgaagccaaagagataaaactttatgcccagattccccctatagagaagatg
gatgcatccttgtccatgcttgctaattgcgagaagctttcactgtctacaaactgcatt
gaaaaaattgccaacctgaatggcttaaaaaacttgaggatattatctttaggaagaaac
aacataaagaacttaaatggactggaggcagtaggggacacattagaagaactgtggatc
tcctacaattttattgagaagttgaaagggatccacataatgaagaaattgaagattctc
tacatgtctaataacctggtaaaagactgggctgagtttgtgaagctggcagaactgcca
tgcctcgaagacctggtgtttgtaggcaatcccttggaagagaaacattctgctgagaat
aactggattgaagaagcaaccaagagagtgcccaaactgaaaaagctggatggtactcca
gtaattaaaggggatgaggaagaagacaactaa

KEGG   Homo sapiens (human): 8632Help
Entry
8632              CDS       T01001                                 

Gene name
DNAH17, DNAHL1, DNEL2
Definition
(RefSeq) dynein axonemal heavy chain 17
  KO
K10408  dynein heavy chain, axonemal
Organism
hsa  Homo sapiens (human)
Pathway
hsa05016  Huntington disease
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09164 Neurodegenerative disease
   05016 Huntington disease
    8632 (DNAH17)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    8632 (DNAH17)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    Dyneins
     8632 (DNAH17)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: MT DHC_N1 AAA_6 DHC_N2 Dynein_C AAA_8 AAA_9 AAA_7 AAA_lid_11 AAA_lid_1 Dynein_heavy AAA_5 Dynein_AAA_lid AAA_16 AAA_30 AAA_22 Sigma54_activat Spc7 ATP_bind_1 Ploopntkinase3 ABC_tran Zeta_toxin
Motif
Other DBs
NCBI-GeneID: 8632
NCBI-ProteinID: NP_775899
OMIM: 610063
HGNC: 2946
Ensembl: ENSG00000187775
Vega: OTTHUMG00000150216
UniProt: Q9UFH2
Position
17q25.3
AA seq 4462 aa AA seqDB search
MTMAPDVRLEYLEEVASIVLKFKPDKWSKLIGAEENVALFTEFFEKPDVQVLVLTLNAAG
MIIPCLGFPQSLKSKGVYFIKTKSENINKDNYRARLLYGDISPTPVDQLIAVVEEVLSSL
LNQSENMAGWPQVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGTLESMER
IPSSLDNLLLHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDTRLLNLKC
IHEQLNRPKVNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLEEME
QADFTMLPTFIAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLSPEEVLK
GLQGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLAFSRINSF
FQRIQTIEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKYDPLD
PGDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMCGGLMERPLILAE
VAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQLKWSLELQERLE
VSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLRCHREKIYQQWVAGVDQDCHFNLGQPL
ILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENETFRKFVGNLELI
VGWYNEIKTIVKAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYIQEVREILHNLQN
RMQKAKQNIEGISQAMKDWSANPLFERKDNKKEALLDLDGRIANLNKRYAAVRDAGVKIQ
AMVAENAELFRADTLSLPWKDYVIYIDDMVLDEFDQFIRKSLSFLMDNMVIDESIAPLFE
IRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRLAKDRMNYKMDLEDNT
DLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIYGCAVTAEDLDTW
TDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRPFKQALLSTIRRW
GFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVMGHLMKVKERQAATD
NMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQVKLTVAPLQANEVSIL
RRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLNKQQKSISAMEGIMEALSKSGGLFE
VPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDM
RSLDKEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQATQVKFKMSEET
TLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPHPRTGTMMLK
SSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLE
SIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLEALKKSL
AICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRL
DASDKPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTLRHEIPEAVVTYE
EKPREQWILDYPAQVALTCTQIWWTTEVGLAFARLEEGYENAIRDYNKKQISQLNVLITL
LMGNLNAGDRMKIMTICTIDVHARDVVAKMIVAKVESSQAFTWQAQLRHRWDEEKRHCFA
NICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDL
GRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQ
DAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKALFRPCAMVVPDFELI
CEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPS
RAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELK
LQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKRKPVAVDLDPK
AVTCDELFGIINPVTREWKDGLFSTIMRDLANITHDGPKWIILDGDIDPMWIESLNTVMD
DNKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWIE
RRKVQSEKANLMILFDKYLPTCLDKLRFGFKKITPVPEITVIQTILYLLECLLTEKTVPP
DSPRELYELYFVFTCFWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKFPSQGTIFDYYID
PDTKKFLPWTDKVPSFELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNAGTG
KSVLMGDKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVYF
IDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPTSGSFTID
SRLQRHFCVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQLVAAALALHQKIT
ATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGDKMVDEK
DQETLHRVTMASTKKFFDDLGDELLFAKPNIFCHFAQGIGDPKYVPVTDMAPLNKLLVDV
LDSYNEVNAVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRLAAYISGL
DVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLINDLLASGE
IPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVILCFSPVGSVLRV
RARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETEGIPWEVKASISFFMSYVHTTVNE
MSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQVD
DLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVEVINKNVTEKQK
ACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMILTAPGGKIPK
DKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDPEFIRSKSTAAAG
LCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAELNANLSNLTSAF
EKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRSQGVTLCGDVLLIS
AFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDDADVATWNNQGLP
SDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSELKAIRLGQKSYLDVIEQAISE
GDTLLIENIGETVDPVLDPLLGRNTIKKGKYIKIGDKEVEYHPKFRLILHTKYFNPHYKP
EMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLL
ARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVKINEARENYRPAAERASL
LYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITYSVYMYTAR
GLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPFKAGVVSPVDFLQHQGWGGIKAL
SEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKTALQKLCMVRCLRPDRMTY
AIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALGKKLGFTI
DNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQNIHLVARWLGTLDKKLEHYSTGSHE
DYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLHKALDLFTQDTLEMCTKE
MEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVPWDD
LRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDVLLAPGFQIPPNLDYKGYHEY
IDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKVKAV
LDDILEKIPETFNMAEIMAKAAEKTPYVVVAFQECERMNILTNEMRRSLKELNLGLKGEL
TITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTV
WLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFME
GARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRMETKNIYECPVYKTRIRGPTYVWTF
NLKTKEKAAKWILAAVALLLQV
NT seq 13389 nt NT seq  +upstreamnt  +downstreamnt
atgacaatggccccggacgtcagactagagtatctggaggaagttgcctccatcgtcctg
aagttcaagccggacaagtggagcaagctgataggcgccgaggagaacgtggccctgttc
acagagttctttgaaaagcccgacgtccaggtgctggtgctgacgctcaatgcagccggc
atgatcataccctgcctgggcttcccccagtccctcaagtccaaaggggtttacttcatc
aagacaaagtccgagaacatcaacaaggacaactacagggcccggctcctttacggcgac
atcagccccacacccgtggaccagctgatcgcggtggtggaggaggtcctctcttctctg
ttaaaccaaagtgagaacatggctggatggccccaggtggtctcggaagacatcgtgaag
caggtccacaggctgaagaatgaaatgtttgtgatgagtggcaagatcaaaggcaaaacc
ttgctgcctattccggagcacctgggcagcctggatggcacgctggagtccatggagagg
atcccctcttcactggacaacttgctcctgcacgccattgaaaccaccatcatcgactgg
tcccaccagatccgggatgtgctgagcaaagactcagcccaggcgctgctggatgggctg
caccccctgccccaagtggagttcgagttctgggacactcggctgctgaacctcaagtgc
atccatgaacagctaaacagacccaaagtgaacaagattgttgagatcctagagaaagcc
aaaagctgctactggccagccctgcaaaacgtttacaccaacgtcactgaagggctgaag
gaagccaacgacatcgtgctctatttgaagcccctacggatcctgctggaggagatggaa
caagccgacttcacgatgctccccaccttcattgccaaggtgctggacaccatctgcttc
atctgggccacctctgagtactataacacacctgccaggatcatcgtcatcctgcaggag
ttctgcaaccaaatcatcgagatgacacgaaccttcctgagcccggaagaggtgctgaag
ggcctgcaaggtgaaatcgaggaagtcctgagtggcatctccctggctgtaaatgtgctg
aaggagctctaccagacgtacgacttctgctgcgtgaacatgaagcttttctttaaggac
aaagagcccgtgccttgggaattcccttcttctcttgccttttccaggataaattccttc
ttccagcgcatccagaccattgaggaactctataaaacagcaattgagtttctgaagctg
gagaaaatcgagcttgggggcgtgcgtgggaacctcctcgggagcctggtgacccgtatc
tatgatgaggtctttgagctggtgaaggtttttgccgactgcaaatatgatcccttggac
cctggagactcgaattttgaccgtgattatgctgattttgagatcaaaatccaagacctg
gataggaggctggccacgatcttttgccaaggatttgatgactgcagctgtatcaagtcc
tccgcaaagctcctgtacatgtgtgggggcctcatggagcggcccctgattcttgccgag
gtggcgcccaggtattcagtcatgctggagctgtttgacgctgagctagacaatgctaag
atcttgtacgatgcccagatggcggcctccgaggaggggaacatccccctgatccacaaa
aacatgcctcccgtggccgggcagctcaaatggagcctggagctgcaggagaggctagag
gtgtccatgaaacacctgaagcacgtcgaacacccggtcatgtctggagcagaggccaag
ctgacctatcagaagtatgacgagatgatggagctgctgaggtgccaccgcgagaagatc
taccagcagtgggtggcgggcgtggaccaggactgccactttaacctggggcagccgctg
attctgcgggacgccgctagcaacctcatccacgtcaacttcagcaaagcgttggtggca
gttctgagagaagtcaagtatttgaatttccagcaacagaaagagattccagacagtgcg
gagagtctgttctcagagaacgaaactttccggaagtttgtgggcaacctggagctcatc
gttggctggtataatgagataaagactatagtgaaggcagtagaatttctactaataaag
tcagaactggaagcaattgatgtcaagttattgagcgctgaaacgacattattctggaat
ggcgaaggtgtgtttcagtacattcaagaggtgcgagaaattctgcacaacttgcagaac
aggatgcaaaaggcaaaacaaaatatagaaggaatttcccaggctatgaaggactggtcg
gccaacccgctgtttgaaagaaaggacaataagaaagaggccctgttagacttggatgga
agaattgccaacctcaacaagcgctacgcagcagtcagggatgctggagtgaagatccaa
gccatggttgcagaaaacgcagaactattcagggcagacacactgagcctgccctggaag
gattatgtcatctacattgacgacatggtcttagatgaatttgaccagttcattcgcaaa
tctctgagtttcctaatggacaacatggttatagatgagagtatcgctcccctgtttgag
atccgcatggagctggacgaggatgggctgaccttcaacccgaccctggaggtgggctca
gatcgcggcttcctggcactgatcgagggcctggtcaacgacatctacaacgtagccagg
ctcatccctcggctggccaaggacaggatgaactacaagatggacctggaagataacaca
gacctcatagagatgagggaggaggtgtccagcctggtcatcaatgccatgaaggaggcc
gaggagtaccaggattcctttgagaggtactcctacctctggacggacaacctgcaggag
tttatgaagaatttcctgatatatgggtgtgcagtcactgcggaggacttggacacctgg
acagatgacaccatccccaagacaccgcccaccctggctcagttccaggagcagatcgac
tcctacgagaagctgtatgaggaggtgtccaagtgcgagaacaccaaggtgttccacggc
tggctgcagtgcgactgccgccccttcaagcaggccctgctcagcacaatccggcgctgg
ggcttcatgttcaagcggcacctgagcaaccacgtcaccaacagcctggctgacctggaa
gccttcatgaaagtcgccagaatgggcttgaccaagcccctcaaggagggggactatgat
gggcttgtggaggtgatggggcacctgatgaaagtcaaggagaggcaagcagccaccgac
aacatgtttgagcccctgaagcaaaccatcgagctgctcaagacctacggggaggagatg
ccagaggagatccacttgaagctgcaggagctgccggagcactgggcaaataccaagaaa
ctggccattcaggtgaagctgaccgtggcaccactccaggccaacgaggtcagcatcctg
cggcggaaatgccagcaattcgagctcaagcaacatgagttcagggagaggttcaggcgc
gaggccccgttctccttcagcgaccccaacccctacaagtccctgaataagcaacaaaag
agcatctccgccatggaaggcatcatggaggcgctgtccaagtccgggggcctgttcgag
gtccccgtcccagactacaagcagctcaaggcctgccaccgggaggtccgcctactgaag
gagctctgggacatggttgttgtggtaaataccagcatcgaggactggaagaccaccaag
tggaaagatatcaacgttgagcagatggacatagattgtaagaagtttgccaaggacatg
aggtctttggacaaggagatgaaaacctgggatgccttcgtggggctcgacaacaccgtg
aaaaacgtgatcacgtccctgcgtgccgtgagcgagctgcagaaccctgccattcgggaa
cgccactggcagcagctcatgcaggccacccaggtgaaatttaaaatgtcagaagagacg
accctggcagatttactgcagctgaacctccacagttacgaggatgaggtccgcaacatc
gtggacaaggccgtgaaggagtcgggcatggaaaaggtgctgaaagccctggacagtacc
tggagcatgatggaattccagcacgagccgcacccgcggacaggcaccatgatgctcaag
tccagcgaggtgctggtggagacgctggaggacaaccaggtgcagctgcagaacctgatg
atgtccaagtacctggcccacttcctgaaggaggtgacaagctggcagcagaagctgtcc
acggcggactccgtcatctccatctggtttgaggtccagcgaacctggagccacctggag
agcatcttcatcggctccgaagacatccgcacccagctcccgggggactcccagcgcttt
gacgacatcaaccaggaattcaaggccttgatggaagatgcagtgaaaacacccaacgtg
gtggaagccaccagcaaacccggcctctacaataaactggaggccctgaagaagagcttg
gccatctgtgaaaaggctttggcagagtatttagagacgaaaagactggctttcccccgg
ttctattttgtctcctcggctgacctcctggacattctctccaatggcaatgaccccgtg
gaggtgagccgccacctgtccaaactcttcgatagcctgtgtaaactgaagttccggctc
gatgccagtgacaaacctctcaaggtgggcctgggaatgtacagcaaggaggacgagtac
atggtttttgatcaggaatgcgacctctcggggcaggtggaagtgtggctgaatcgagtg
ctggaccgaatgtgctctaccctccggcacgaaatcccagaggccgtggtgacctacgaa
gagaagccgagggagcagtggatcctggactacccagcccaggtggccctgacttgcacc
cagatctggtggacgaccgaggtgggcctggcatttgccaggctggaggaaggctatgaa
aacgctatcagagattataacaaaaagcagattagccagctgaacgtactcatcacgctg
ctcatggggaacctcaacgctggcgacaggatgaagatcatgaccatctgcaccatcgat
gtgcacgcacgggacgtggtggccaaaatgatcgtggccaaggtggagagttctcaggcc
ttcacctggcaggcccagctccggcatcgctgggacgaagagaagcgacactgctttgcc
aacatctgcgatgcccaaatccagtattcctatgagtatctgggcaacacgccgcggctg
gtcatcaccccactcactgacaggtgctatatcaccctgacccagtccctccatctcatc
atgggtggagcccctgccggccccgctgggaccggcaagactgagacgaccaaggacctg
ggcagagccctgggcaccatggtctacgtcttcaactgctccgagcagatggactacaag
tcctgtggaaatatctacaagggcctggcccagacgggagcctggggctgctttgacgag
tttaatcgcatctcagtggaagtcttgtctgtgattgccgtgcaggtaaaatgtgtccag
gatgcaattcgggccaagaaaaaagcattcaatttcctgggagagatcataggcctcatt
cccaccgtcggtatcttcatcaccatgaaccctgggtacgccggacgcgcggagctgcct
gagaacctaaaagccttattcaggccctgtgccatggtcgtccccgacttcgaactgata
tgtgagatcatgctcatggccgagggctttctggaagcccgccttctggccaggaagttc
atcaccctgtacaccttgtgcaaggagctgctctcgaagcaggatcattacgactggggc
ctgagagccatcaagtctgtgctggtggtggccggctccctgaagaggggcgaccccagc
cgggcagaggaccaggtgctcatgcgggcgctgagagacttcaacatccccaagattgtg
acagacgacctgcccgtattcatgggactgatcggggacctcttcccggctctggacgtg
cctcggaaacgggacctgaattttgaaaagatcatcaagcagagcatcgtggagctcaag
ctgcaggcggaggacagcttcgtgctgaaggtggtgcagctggaggagctgctgcaggtc
cgccactccgtgttcatcgtcgggaatgcgggcagcggcaaatctcaggtcctcaaatcc
ctcaacaagacctatcagaacctgaagaggaagccggtcgccgtggacctggaccccaag
gccgtcacctgcgacgagctctttggcatcatcaacccagtgaccagggaatggaaagat
ggcctgttctccaccatcatgcgagacctggccaacatcacccatgacggccccaagtgg
atcatccttgacggagacatagaccccatgtggatcgagtctctcaacacagtcatggat
gacaacaaggtcctcaccctggccagcaacgagcggatccccctgaaccgcaccatgagg
ctggtgttcgaaatcagccacctgaggacggccaccccagccaccgtttccagagccggc
atcctctacatcaacccagccgacctgggatggaacccggtggtgagcagctggatcgag
aggcgcaaggtgcagtcggagaaggccaacctgatgatcctctttgacaagtacctgccc
acgtgcctggacaagttgcgctttgggttcaagaagatcacgccagtgccggagatcacg
gtgatccaaacgattctgtacctgctggagtgcctgctcacggagaagaccgtgcccccc
gactcccccagggagctgtacgagctgtacttcgtgttcacctgcttctgggccttcggt
ggcgccatgttccaggaccagcttgtggattatcgagtggagttcagtaaatggtggatc
aacgaattcaagactatcaagttcccctcgcagggaacgatttttgactactacattgat
cctgacacaaaaaagttcctgccctggacagataaagtgccctcctttgagctggatccc
gatgtcccactgcaggcctctttggtccacaccacggaaaccatccgcatccgctacttc
atggacctgctcatggagaagtcctggccggtgatgctggtggggaacgcggggacgggc
aagtcggtgctgatgggggacaagctggaaagcctgaacacggacaactacctggtgcag
gctgtgcccttcaacttctacacgacctcagccatgctgcagggggtgctggagaagccg
ctggagaagaaatcggggaggaactacgggccgccaggcactaagaagctcgtctacttc
atcgacgacatgaacatgcccgaggtggacaagtatgggacggtggccccgcacaccctc
atccggcagcacatggaccaccggcactggtatgacagacataagctgacgttaaaagat
atccataattgtcagtacgtggcctgcatgaaccccacttccggatccttcaccatcgac
tccaggcttcagcgccatttctgcgtgtttgctgtgagcttccccggccaggaggccctc
accaccatctacaacacaatcctgacgcagcacctggccttccgctcggtctccatggct
atccagaggataagcagccagctggtggccgcggccctggctttgcatcagaaaatcacg
gcaacatttcttcccacggccattaagtttcattatgtcttcaacctcagggacctctcc
aatattttccagggactcttattttccacagcagaagttctgaaaaccccactggacctc
gtccgcctttggctacatgagactgaacgagtgtatggtgacaaaatggttgacgaaaaa
gaccaggaaacattgcatagagtcaccatggcctccaccaagaagttctttgatgatctt
ggtgatgaactcttatttgccaagccaaatatcttctgccactttgctcaagggattggc
gatcccaaatatgttcctgtaaccgacatggctcctctgaacaagctcctcgtggacgtc
ctggacagctacaatgaagttaatgcagtcatgaatttggtgctgtttgaggacgccgtg
gctcacatctgcaggattaatcgcatcctggagtctccccgggggaatgccctgctggtg
ggggtgggcggcagtggcaaacagagcctctcccgcctggcagcgtacatcagcgggctt
gacgtgtttcagatcaccctcaagaagggctacgggatccccgacctcaagattgacctc
gctgctcagtacataaaggctgccgtgaagaacgttccctcggtgttcctgatgacagac
tcccaggtggccgaggagcagtttctggtgctgatcaatgacctgctggcctcaggagag
atccctgggctgtttatggaggacgaggtggagaacatcatctcctccatgcgaccccaa
gtcaagtcccttggcatgaatgacactcgggaaacatgttggaagttcttcatcgaaaaa
gtgcgcagacagctcaaggtgatcctgtgtttctcccctgtgggctccgtgctgcgggta
cgagccagaaagttcccagctgtggtcaactgcacggccatcgactggttccacgagtgg
ccggaagatgcgctggtgtccgtcagcgcccgcttcctggaggagactgaggggattccg
tgggaagtcaaggcctccatcagcttcttcatgtcctacgtgcacaccaccgtcaacgag
atgtccagggtatacctggctactgagaggcgctacaactacaccacacccaaaaccttt
ctggagcagatcaaactgtaccagaacctgctggccaagaagagaacggaacttgttgcc
aaaatcgagaggctggagaacggcctgatgaagctgcagagcacggcttcccaggtggat
gatttgaaagccaagttggcgattcaggaggctgagctcaagcagaagaatgagagcgca
gaccaactgatccaggtggtcggcatcgaggccgagaaggtcagcaaagagaaggccatt
gctgaccaggaagaagtcaaggtcgaggtcatcaataagaacgtcactgagaagcaaaag
gcctgtgaaacagacctggccaaagcagaaccggccctgctggcagcccaggaggctctg
gacactctgaataagaacaacctgacagagctgaagtcctttgggtccccgccggatgct
gtggtcaacgtcaccgccgccgtcatgattctgaccgcacctgggggcaagatccccaag
gacaagagctggaaggcggccaagatcatgatgggcaaggtggacaccttcctagactcc
ctgaagaagttcgacaaggagcacatccctgaggcctgcctgaaggccttcaagccctac
caaggcaacccgacgttcgaccccgagttcatccgctccaagtccacggccgccgccggc
ctgtgctcctggtgcatcaacatcgtccgcttctacgaggtctactgcgacgtggcgccc
aagaggcaggcactggaggaggctaatgcagagctggcagaggcacaagagaagctgtcc
cggatcaaaaacaagattgccgaacttaacgccaacctgagcaacctaacctcagcgttt
gaaaaagcaacagctgagaaaatcaagtgtcagcaagaggccgatgccacgaacagggtg
atcttactggcgaacaggctggtcgggggattagcatcggaaaacatccgctgggctgag
tctgtggagaacttcaggagccagggggtcacgctgtgtggggacgtcctgctcatctct
gccttcgtgtcctacgtgggctacttcaccaagaaataccggaatgagctgatggagaaa
ttctggatcccttacatacataacttaaaggtccccatcccgatcacgaatggcctggat
cccttgagcctgctgacagatgacgcggacgtggccacctggaacaaccagggcctcccc
agcgaccgcatgtccaccgagaatgccaccatcctgggcaacaccgagcggtggccgctg
atcgtggacgcccagctccaaggaatcaagtggatcaaaaacaaatacaggagtgaactg
aaagccatccgcctgggacagaagagctacctggatgtcatcgagcaggccatctcggaa
ggggacaccttgctcattgagaacatcggcgaaaccgtggaccccgtgctggaccctcta
ctgggcaggaacacgattaaaaagggaaagtacattaagatcggtgacaaggaggtggag
taccaccccaagttccgcctgatcctacacaccaagtacttcaacccacactacaagcca
gagatgcaggctcagtgcaccctcatcaacttcctggtcaccagggatggactcgaggac
caactcttggccgctgtggtggccaaagagcgcccagatctggaacagctgaaggcaaac
ctcaccaagtctcaaaacgaatttaagattgttctgaaagagctggaagattcgctcctg
gcccgtctgtcggctgcgtcggggaactttctgggagacacggccttggtggagaatctg
gagaccaccaagcacacagccagcgagatcgaggagaaggtggtggaggcaaaaatcaca
gaagttaaaatcaacgaagcgagagagaactaccgcccggctgcggagagggcatctctg
ctctacttcatactgaacgatctcaacaaaatcaaccccgtctaccagttctccctcaag
gccttcaacgtggtgtttgagaaagccatccagaggaccacccctgccaacgaggtgaag
cagcgggtgatcaacctgacggacgagatcacctactccgtctacatgtacacggcccgg
ggactcttcgagagggacaaactcattttcctggcacaagttacgtttcaggtcctgtcc
atgaagaaggagctgaacccagtggagctggatttcctcctgcggttcccttttaaggcc
ggagtggtctcaccagtggacttcctccagcatcaaggctggggcgggatcaaggccctc
tcggagatggatgagttcaaaaatctggacagtgacatcgaaggatctgccaagcgctgg
aaaaagctggtggagtcggaagcccccgagaaggagatcttccccaaggagtggaagaac
aagacggccctgcagaagctgtgcatggtgcgctgcctgcggccagatcgcatgacctac
gctatcaagaacttcgtggaggaaaagatgggcagcaagttcgtggaaggccggagtgtt
gagttttctaagtcctacgaggagagcagcccctccacgtcaatcttcttcatcctctcc
ccgggggttgaccccttgaaagacgtggaagccctgggaaaaaaactagggtttaccata
gacaatggaaaactccataatgtgtccctggggcagggacaagaggtggtggctgagaac
gccctggacgtggctgcagagaaaggacactgggtcattctgcagaatatccacctggtg
gcccggtggctgggaacactggacaagaagctggagcactacagcacgggcagccatgag
gactaccgggtgttcatcagcgcggagcctgcccccagccccgagacccacatcatcccc
cagggcattctggagaacgccatcaagatcaccaacgagccccccacgggcatgcacgcc
aacttgcacaaggccctggacctgttcacccaggacaccctggagatgtgcaccaaggag
atggagttcaagtgcatgctcttcgccctgtgctacttccacgctgtggtggcagagagg
cgcaagttcggcgcccagggctggaaccggtcgtaccccttcaacaacggggacctcacc
atctccatcaacgtgctctacaactacctggaggccaaccccaaggtgccctgggacgat
ctccgctacctttttggtgaaatcatgtatggcggccacatcacagatgactgggaccgt
cggctgtgcaggacctacctggctgaatacatccggacggagatgctggagggagacgtc
ctgctggcccccggctttcagatcccccccaacctggactacaagggttaccacgaatac
atcgatgagaacctgccccctgagagtccctatctgtatggcctgcaccccaacgcagag
attggctttctgacggtcacctcagagaagctgttccgcactgtcctggaaatgcagcca
aaagagacggactcgggggcaggcacgggagtgtcccgcgaggagaaggtgaaggccgtg
ctggacgacatcctggagaagattccggagactttcaacatggctgagatcatggcaaag
gcagcggaaaagaccccctacgtggtagtcgcctttcaagaatgtgaaagaatgaacatc
ctgaccaacgaaatgcgccgttcgctcaaggagctgaacctggggctgaagggagaactg
accatcacgaccgacgtggaagatctgtccacggctctcttctatgacaccgtgcctgat
acgtgggtggcccgggcctacccctccatgatgggcctggcggcctggtacgcagacctg
ctgctccgcatcagggaactcgaggcctggacgacagactttgccctgcccaccaccgtg
tggctggccggcttcttcaacccccagtcgttcctcacggccatcatgcagtccatggcc
aggaagaacgagtggcccctggacaagatgtgtctgtctgtcgaggtgaccaagaaaaac
cgagaggacatgaccgctcctccgcgagagggctcctacgtgtacggactcttcatggaa
ggggctcgctgggacacccagactggagtcatcgctgaagcgcggctgaaagagctgacc
ccggccatgcctgtcatcttcatcaaggccattcctgtggaccgcatggagaccaagaac
atctatgagtgtcccgtgtacaaaacacgcatccgcggccccacctatgtctggaccttt
aacttgaagaccaaagagaaggcagcgaagtggatcctggcagccgtggcgctgctccta
caggtttag

KEGG   Homo sapiens (human): 8701Help
Entry
8701              CDS       T01001                                 

Gene name
DNAH11, CILD7, DNAHBL, DNAHC11, DNHBL, DPL11
Definition
(RefSeq) dynein axonemal heavy chain 11
  KO
K10408  dynein heavy chain, axonemal
Organism
hsa  Homo sapiens (human)
Pathway
hsa05016  Huntington disease
Disease
H00564  Primary ciliary dyskinesia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09164 Neurodegenerative disease
   05016 Huntington disease
    8701 (DNAH11)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    8701 (DNAH11)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    Dyneins
     8701 (DNAH11)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: MT DHC_N1 AAA_6 DHC_N2 AAA_8 Dynein_C AAA_9 AAA_7 AAA_lid_11 AAA_lid_1 Dynein_heavy Dynein_AAA_lid AAA_5 AAA_16 AAA_22 AAA AAA_30 Laminin_II AAA_25 FAM177
Motif
Other DBs
NCBI-GeneID: 8701
NCBI-ProteinID: NP_001264044
OMIM: 603339
HGNC: 2942
Ensembl: ENSG00000105877
Vega: OTTHUMG00000152524
Pharos: Q96DT5(Tbio)
UniProt: Q96DT5 H9NAJ7 Q96NT7 H9NAJ8
Position
7p15.3
AA seq 4516 aa AA seqDB search
MAAQVAAREARDFREAPTLRLTSGAGLEAVGAVELEEEEENEEEAAARRARSFAQDARVR
FLGGRLAMMLGFTEEKWSQYLESEDNRQVLGEFLESTSPACLVFSFAASGRLAASQEIPR
DANHKLVFISKKITESIGVNDFSQVVLFGELPALSLGHVSAFLDEILVPVLSNKNNHKSW
SCFTSQDMEYHIEVMKKKMYIFRGKMSRRTLLPIPTVAGKMDLDQNCSENKPPSNERIIL
HAIESVVIEWSHQIQEIIERDSVQRLLNGLHLSPQAELDFWMMRRENLSCIYDQLQAPVV
LKMVKILTTKQSSYFPTLKDIFLAVENALLEAQDVELYLRPLRRHIQCLQETEFPQTRIL
IAPLFHTICLIWSHSKFYNTPARVIVLLQEFCNLFINQATAYLSPEDLLRGEIEESLEKV
QVAVNILKTFKNSFFNYRKKLASYFMGRKLRPWDFQSHLVFCRFDKFLDRLIKIEDIFAT
TLEFEKLERLEFGGTKGAILNGQVHEMSEELMELCKLFKQSTYDPSDCTNMEFESDYVAF
KSKTLEFDRRLGTIICEAFFNCNGLEAAFKLLTIFGNFLEKPVVMEIFSLHYSTLVHMFN
TELDVCKQLYNEHMKQIECGHVVLNKNMPFTSGNMKWAQQVLQRLQMFWSNFASLRYLFL
GNPDHALVYQKYVEMTTLLDQFESRIYNEWKSNVDEICEFNLNQPLVKFSAINGLLCVNF
DPKLVAVLREVKYLLMLKKQDIPDSALAIFKKRNTILKYIGNLDLLVQGYNKLKQTLLEV
EYPLIEDELRAIDEQLTAATTWLTWQDDCWGYIERVRAATSELEHRVERTQKNVKVIQQT
MRGWARCVLPPRREHRREAAFTLEDKGDLFTKKYKLIQGDGCKIHNLVEENRKLFKANPS
LDTWKIYVEFIDDIVVEGFFQAIMHDLDFFLKNTEKQLKPAPFFQAQMILLPPEIVFKPS
LDREAGDGFYDLVEEMLCNSFRMSAQMNRIATHLEIKNYQNDMDNMLGLAEVRQEIMNRV
VNVINKVLDFRNTLETHTYLWVDDRAEFMKHFLLYGHAVSSDEMDAHANEEIPEQPPTLE
QFKEQIDIYEALYVQMSKFEDFRVFDSWFKVDMKPFKVSLLTIIKKWSWMFQEHLLRFVI
DSLNELQEFIKETDSGLQRELNEGDHDGLVDIMVHLLAVRSRQRATDELFEPLKETITLL
ESYGQKMPEQVYIQLEELPERWETTKKIAATVRHEVSPLHNAEVTLIRKKCILFDAKQAE
FRERFRHYAPLGFNAENPYTALDKANEELEALEEEMLQMQESTRLFEVALPEYKQMKQCR
KEIKLLKGLWDVIIYVRRSIDNWTKTQWRQIHVEQMDVELRRFAKEIWSLNKEVRVWDAY
TGLEGTVKDMTASLRAITELQSPALRDRHWHQLMKAIGVKFLINEATTLADLLALRLHRV
EDDVRRIVDKAVKELGTEKVITEISQTWATMKFSYEVHYRTGIPLLKSDEQLFETLEHNQ
VQLQTLLQSKYVEYFIEQVLSWQNKLNIADLVIFTWMEVQRTWSHLESIFVCSEDIRIQL
VKDARRFDGVDAEFKELMFKTAKVENVLEATCRPNLYEKLKDLQSRLSLCEKALAEYLET
KRIAFPRFYFVSSADLLDILSKGAQPKQVTCHLAKLFDSIADLQFEDNQDVSAHRAVGMY
SKEKEYVPFQAECECVGHVETWLLQLEQTMQETVRHSITEAIVAYEEKPRELWIFDFPAQ
VALTSSQIWWTTDVGIAFSRLEEGYETALKDFHKKQISQLNTLITLLLGELPPGDRQKIM
TICTIDVHARDVVAKLISQKVVSPQAFTWLSQLRHRWEDTQKHCFVNICDAQFQYFYEYL
GNSPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGMMVYVFNCS
EQMDYKSIGNIYKGLVQTGAWGCFDEFNRISVEVLSVVAVQVKMIHDAIRNRKKRFVFLG
EAITLKPSVGIFITMNPGYAGRTELPENLKALFRPCAMVAPDIELICEILLVAEGFVDAR
ALARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDKNRPEDQVLMRALRDF
NMPKIVTDDIPVFLGLVGDLFPALDVPRRRKLHFEQMVRQSTLELRLQPEESFILKVVQL
EELLAVRHSVFVVGNAGTGKSKILRTLNRTYVNMKQKPVWNDLNPKAVTTDELFGFIHHA
TREWKDGKIVYSYFIGLFSSILREQANLKHDGPKWIVLDGDIDPMWIESLNTVMDDNKVL
TLASNERIALTPFMRLLFEIHHLRSATPATVSRAGILYVNPQDLGWNPYVASWIDRRRHQ
SEKANLTILFDKYVPACLDKLRTSFKTITSIPESSLVQTLCVLLECLLTPENVPSDSPKE
VYEVYFVFACIWAFGGTLLQDQISDYQADFSRWWQKEMKAVKFPSQGTIFDYYVDHKTKK
LLPWADKIAQFTMDPDVPLQTVLVHTTETARLRYFMELLLEKGKPLMLVGNAGVGKTVFV
GDTLASLSEDYIVSRVPFNYYTTSTALQKILEKPLEKKAGHNYGPGGNKKLIYFIDDMNM
PEVDLYGTVQPHTLIRQHIDYGHWYDRQKVMLKEIHNCQYVACMNPMVGSFTINPRLQRH
FTVFAFNFPSLDALNTIYGQIFSFHFQQQAFAPSILRSGPTLIQATIAFHQTMMCNFLPT
AIKFHYIFNLRDLSNVFQGILFASPECLKGPLDLIHLWLHESARVYGDKLIDKKDCDLFQ
RRMLETAYKYFEGIDSHMLLQQPLIYCHFADRGKDPHYMPVKDWEVLKTILTETLDNYNE
LNAAMHLVLFEDAMQHVCRISRILRTPQGCALLVGVGGSGKQSLSRLAAYLRGLEVFQIT
LTEGYGIQELRVDLANLYIRTGAKNMPTVFLLTDAQVLDESFLVLINDLLASGEIPDLFS
DEDVDKIISGIHNEVHALGMVDSRENCWKFFMARVRLQLKIILCFSPVGRTLRVRARKFP
AIVNCTAIDWFHAWPQEALVSVSRRFIEETKGIEPVHKDSISLFMAHVHTTVNEMSTRYY
QNERRHNYTTPKSFLEQISLFKNLLKKKQNEVSEKKERLVNGIQKLKTTASQVGDLKARL
ASQEAELQLRNHDAEALITKIGLQTEKVSREKTIADAEERKVTAIQTEVFQKQRECEADL
LKAEPALVAATAALNTLNRVNLSELKAFPNPPIAVTNVTAAVMVLLAPRGRVPKDRSWKA
AKVFMGKVDDFLQALINYDKEHIPENCLKVVNEHYLKDPEFNPNLIRTKSFAAAGLCAWV
INIIKFYEVYCDVEPKRQALAQANLELAAATEKLEAIRKKLVDLDRNLSRLTASFEKATA
EKVRCQEEVNQTNKTIKLANRLVKELEAKKIRWGQSIKSFEAQEKTLCGDVLLTAAFVSY
VGPFTRQYRQELVHCKWVPFLQQKVSIPLTEGLDLISMLTDDATIAAWNNEGLPSDRMST
ENAAILTHCERWPLVIDPQQQGIKWIKNKYGMDLKVTHLGQKGFLNAIETALAFGDVILI
ENLEETIDPVLDPLLGRNTIKKGKYIRIGDKECEFNKNFRLILHTKLANPHYKPELQAQT
TLLNFTVTEDGLEAQLLAEVVSIERPDLEKLKLVLTKHQNDFKIELKYLEDDLLLRLSAA
EGSFLDDTKLVERLEATKTTVAEIEHKVIEAKENERKINEARECYRPVAARASLLYFVIN
DLQKINPLYQFSLKAFNVLFHRAIEQADKVEDMQGRISILMESITHAVFLYTSQALFEKD
KLTFLSQMAFQILLRKKEIDPLELDFLLRFTVEHTHLSPVDFLTSQSWSAIKAIAVMEEF
RGIDRDVEGSAKQWRKWVESECPEKEKLPQEWKKKSLIQKLILLRAMRPDRMTYALRNFV
EEKLGAKYVERTRLDLVKAFEESSPATPIFFILSPGVDALKDLEILGKRLGFTIDSGKFH
NVSLGQGQETVAEVALEKASKGGHWVILQNVHLVAKWLGTLEKLLERFSQGSHRDYRVFM
SAESAPTPDEHIIPQGLLENSIKITNEPPTGMLANLHAALYNFDQDTLEICSKEQEFKSI
LFSLCYFHACVAGRLRFGPQGWSRSYPFNPGDLTICASVLYNYLEANSKVPWEDLRYLFG
EIMYGGHITDDWDRKLCRVYLEEFMNPSLTEDELMLAPGFAAPPYLDYAGYHQYIEEMLP
PESPALYGLHPNAEIEFLTVTSNTLFRTLLEMQPRNALSGDELGQSTEEKVKNVLDDILE
KLPEEFNMAEIMQKNSNRSPYVLVCFQECERMNILIREIRISLEQLDLSLKGELALSPAV
EAQQFALSYDTVPDTWSKLAYPSTYGLAQWFNDLLLRCRELDTWTQDLTLPAVVWLSGFF
NPQSFLTAIMQTMARKNEWPLDKTRLTADVTKKTKEDYGHPPREGAYLHGLFMEGARWDT
QAGTIVEARLKELACPMPVIFAKATPVDRQETKQTYECPVYRTKLRGPSYIWTFRLKSEE
KTAKWVLAGVALLLEA
NT seq 13551 nt NT seq  +upstreamnt  +downstreamnt
atggcagcccaggtggcagcccgggaggcgcgagacttcagagaagccccgacccttcgc
ctaacctcgggggccggcctggaggcagtgggcgctgtggagctcgaggaggaggaggag
aacgaggaggaggcggcggccaggagagcgcggagtttcgcccaagacgcgcgggtgcgc
ttcctcggcggccgcctggcgatgatgctggggttcacggaggagaaatggagccagtat
ttggaaagcgaggacaaccggcaggttcttggggagtttctggaaagcaccagcccggct
tgccttgtgtttagcttcgccgcctcggggcgccttgcggcttcccaggagattccaaga
gatgcaaaccataaacttgtttttatttccaagaagattactgaaagcattggagtaaat
gacttttctcaagtggttttatttggagagttacctgcgttgtctcttggacatgtatct
gctttccttgatgagattttagtgccagttctttctaataagaacaaccataagtcctgg
tcctgttttacttcacaagatatggaatatcacatagaagtcatgaaaaagaagatgtat
atttttaggggcaaaatgtctagaagaactcttctaccaattcccactgttgcaggaaag
atggatctggatcagaattgttcagagaacaagccaccgtcaaacgaaaggataatactt
catgcaattgaatctgtggttattgaatggtcacatcaaatccaagaaattatagaaaga
gattcagtgcagcgtttgttgaatggtcttcacttgtctcctcaagcagaactagatttc
tggatgatgaggagagaaaatctgtcatgcatttatgatcaacttcaggcacctgttgtc
ctcaaaatggttaagatcctgacaactaaacaaagcagctattttcctactctgaaggac
atttttctggctgtggaaaatgctcttctcgaagcccaagatgtggaactttacctgaga
cctctgaggagacacatccagtgtctccaggagacggaattcccacagacacgcatatta
atcgctccattatttcataccatctgtctgatctggagtcattccaagttttataacacc
ccagctcgggttatagttttattgcaagagttttgtaatctcttcattaaccaggcaaca
gcttacctttcacctgaggaccttttgaggggagaaatagaagagtcactggaaaaggtg
caggtggctgttaacatcttaaagactttcaaaaactcctttttcaactatagaaaaaaa
ttggcaagctactttatgggaagaaagctgagaccatgggatttccagtctcatctggtg
ttttgcagatttgacaagtttcttgatcgtttaataaaaatagaggatatatttgccacc
actttggaatttgaaaagctggaaagactggaatttggtggtaccaaaggagcaatttta
aatggacaagtccacgagatgagtgaagaacttatggaactctgtaaactttttaaacag
agcacttatgacccatctgattgcactaacatggagtttgaaagtgattatgtggcattt
aagtccaaaactctggaatttgacagaaggcttgggacaattatttgtgaagctttcttt
aactgcaatggcttagaagctgcatttaagcttttgaccatatttggaaattttctagag
aagccagttgtcatggaaattttcagcctacattacagcacactagtgcatatgtttaat
acagagctggatgtgtgtaagcaactgtataatgaacacatgaaacagattgaatgtggt
catgtagttcttaacaagaacatgccatttacctcaggaaatatgaaatgggcccagcag
gttctccaacgacttcaaatgttttggtcaaacttcgcatctctccgttatctatttttg
ggcaatcctgatcacgctttagtttatcaaaagtatgttgaaatgaccactttgcttgat
caatttgaaagtcgtatctataatgaatggaaaagtaatgtggatgaaatctgtgaattc
aatttgaatcaacccttggttaaattcagtgccataaatggtcttctctgtgtcaatttt
gacccaaagctagtggctgtattgagagaagtgaaatatcttttgatgttgaagaaacaa
gacataccagattcagctttagccatcttcaagaaaaggaacactattttaaagtacatt
ggaaatcttgaccttcttgtgcaagggtataataaactcaaacagacgctcctggaagtt
gaataccctctgattgaagatgagctgagggctattgacgagcagctgacagcagccaca
acgtggctgacatggcaggatgactgctggggctacatcgagagggtgagggcagccacg
tccgagttggagcacagagttgagcgcacacagaaaaacgtgaaggtgatccagcagacc
atgaggggctgggccaggtgcgtgctacctcccaggagagagcacagacgagaggcagcc
ttcaccttggaggacaagggtgatttgtttacaaaaaaatacaagttaatccaaggagat
ggctgcaagatccacaacttggtcgaggaaaataggaagctcttcaaagccaatccctct
ctggatacctggaaaatttatgtagaattcattgacgacattgtggtggaaggctttttt
caggctataatgcacgacttagacttctttctgaagaatacagagaaacaattgaaaccg
gcaccgttttttcaagcacaaatgatcttgttgcctcctgagattgtgtttaaaccttcc
ctagacagagaggctggggatggcttctatgatcttgtagaagaaatgttatgcaatagt
tttagaatgtctgcccagatgaaccgaatagcaacacacctggaaattaaaaattatcag
aatgatatggataacatgttaggcctggcagaggtcaggcaggagatcatgaacagagtg
gtgaatgtcatcaacaaagtcttagatttcagaaacaccctggagacccacacttacctc
tgggtggatgatcgagctgagtttatgaagcattttctcttgtatggccatgctgtgtct
tccgatgaaatggatgctcatgcaaatgaagaaattcccgaacaaccaccaactcttgag
caattcaaagaacagattgacatttatgaagctttgtatgttcaaatgagcaaatttgag
gactttagagtgtttgatagttggttcaaggtggacatgaagcctttcaaagtgagcttg
ttaaccataattaagaaatggagctggatgtttcaggagcatcttttgagatttgtcatt
gacagtctgaatgagctacaagaatttataaaggagacagattccggacttcagagagaa
ttaaatgaaggtgatcatgatggtttagttgacatcatggtgcatcttctggctgtaaga
agccgacagagagctactgatgaactctttgaacctctaaaagaaacgatcaccctcttg
gaaagctatggccagaagatgcctgagcaggtctatattcagctagaggaattacctgaa
agatgggaaactaccaaaaagatcgcagcaactgtcagacatgaagtctcacctctccat
aatgcggaagtcactcttataaggaaaaaatgtattttgtttgacgcaaagcaggcagag
ttcagagagagattcagacactatgcccctcttggatttaatgcagaaaatccatacaca
gcgcttgataaggcaaatgaagagcttgaggccttagaagaagaaatgttgcagatgcaa
gaatctactcgtctttttgaagtggctcttccagagtacaaacaaatgaaacagtgtcgc
aaagaaataaaattgctcaagggactgtgggatgtcattatttatgttcgaagaagcatt
gataattggactaaaacccagtggagacagattcatgtggaacagatggatgtagaactc
agaaggtttgccaaggaaatttggtcactcaacaaggaagtccgcgtctgggatgcttac
acgggcctggaaggcacagttaaggacatgacagcctccctgagggccatcacagagtta
cagagccctgccctcagggacaggcattggcaccagctgatgaaagctattggggtcaag
tttttaataaatgaagccacaactttggcagatttgttagcactgcggttacacagagtg
gaagatgatgtccgaaggattgtggacaaggcggtgaaagagctggggactgagaaggtt
attactgaaatcagtcagacctgggcaaccatgaagttttcttacgaagttcactatcga
acaggcattccattactaaagtctgatgaacaactttttgaaactctagagcacaaccaa
gttcagttgcagactcttcttcaaagcaagtatgtagaatatttcattgagcaagtgtta
agctggcaaaataaattaaacatagcagacttggtcatcttcacttggatggaagtccag
cgaacttggtctcacctggaaagcatttttgtctgttcagaagatattcgaatccagctt
gtgaaagatgctagaagatttgatggggtggatgctgaatttaaggagttaatgttcaag
acagccaaagtagaaaatgtgttagaagcaacgtgcagacctaatctctatgaaaaactt
aaagatttacagtccaggctttctctttgtgaaaaagctctcgctgaatacctggaaacc
aagcgcatagcctttcctcgcttctatttcgtctcttctgctgatttacttgacattctc
tcaaaaggagctcagcctaaacaggtaacatgtcaccttgccaaacttttcgacagcatt
gcagatctgcagtttgaagacaatcaggatgtttctgcacacagggcagttggaatgtac
agcaaagaaaaggagtatgtcccattccaagccgagtgtgaatgtgtgggccatgtggaa
acatggcttctgcaacttgaacagactatgcaagaaacggtgcgtcattctataacagaa
gccatagtggcctacgaggaaaaacctagggaactgtggatttttgatttcccagctcag
gttgcactaaccagctcacaaatatggtggaccacagatgtaggaatagccttcagtaga
ctggaagaaggctacgaaacagccctgaaggatttccataaaaaacagatttctcagctg
aatacactgattacacttttgctgggagaacttccacctggagacagacagaagatcatg
acaatttgtaccatagatgtccatgccagagacgtggtggcaaaacttatttctcagaag
gttgtcagtccccaagcttttacatggctgtctcaacttcgtcaccgatgggaggatacc
cagaaacactgctttgttaatatttgtgatgcccagttccagtacttctatgaatactta
ggaaacagccctcgactagtgatcactcctctaactgacaggtgttatattaccttaact
caatcacttcatctaaccatgagtggggctcctgctggcccagctggtaccgggaaaaca
gagaccaccaaagacctaggacgtgcccttggcatgatggtctatgtattcaactgttca
gagcaaatggactacaaatccataggcaatatctataagggattggtgcagacaggagct
tggggctgctttgatgagttcaaccgaatctctgtggaagttctgtcagtggtggcagta
caagtgaaaatgattcatgatgccatcagaaacaggaagaagagatttgtatttcttggg
gaagctatcacactgaagccatcagttggaatatttattactatgaacccgggttatgct
ggtcgaaccgaattaccggaaaatctcaaagctcttttcagaccctgtgccatggtggcc
cctgacattgagctaatctgtgaaatcttgttagttgctgaaggttttgtggatgcgcgt
gcattagcccgaaagttcattacgttgtacacgctttgcaaggagcttctctccaagcag
gatcattacgactggggacttcgtgctattaagtctgtcttggttgtggctggatctctg
aaacgaggagataaaaatagacccgaagatcaggtactcatgagagcattaagggatttc
aatatgcccaaaatagtgactgacgacatcccagtgtttctgggcctggtcggtgacctg
tttccagccctggatgtgccccggaggaggaagctgcactttgaacagatggtcaggcag
tctaccctggagctccgcctgcagcctgaagagagcttcatcctcaaagttgtccagctt
gaggaactgttggctgtgcggcactcggtctttgtagttggaaatgcaggcacaggaaag
agtaagattttgagaacactgaaccgaacatatgttaacatgaaacagaagccggtttgg
aatgacttaaaccctaaagctgtgacaacagatgaactctttggtttcatacatcatgct
acccgagaatggaaagatggcaagattgtttactcttattttataggtctcttctcatcc
attctacgagaacaagcaaatcttaagcatgatggaccaaaatggatagtcctggatggc
gatattgaccccatgtggattgaatcactgaatactgtaatggatgataacaaggtgctg
accctcgccagcaatgagcgcattgcactcactcccttcatgaggcttctgtttgagata
catcacttaaggagcgcaaccccggccactgtttccagagctggtattctgtatgtgaac
ccacaagatctgggctggaatccgtatgtggccagttggatagacagaaggcggcatcaa
tcagaaaaggccaatttgactattctttttgataaatatgtccctgcatgcttggataaa
ctgagaacaagctttaaaaccatcacttcaattcctgagagtagcctggtgcagactcta
tgtgttcttttggagtgcttgctgactcctgaaaatgtaccttctgacagcccaaaagaa
gtttatgaagtctattttgtatttgcttgtatctgggcttttggaggcaccctgctacaa
gatcagatttctgattatcaagctgacttcagtcggtggtggcagaaagagatgaaagca
gtgaaatttccgtcgcagggaacaatctttgattattatgtggaccacaaaactaagaaa
ttattgccctgggctgacaaaattgcccagtttactatggatccagatgtgcctctgcag
acagttctcgttcacacaacagagacagctcgtcttagatatttcatggagttgttgctt
gagaaaggaaaacctctaatgctagtaggaaatgcaggagtgggaaaaacagtctttgta
ggtgacacattggcaagtctctctgaggattacatagtatcccgtgtgcctttcaactac
tacacgacatccacagctctgcaaaaaattcttgagaaacccctagagaaaaaagctggt
cataactatggtcctggaggaaataaaaaattgatttattttatcgacgacatgaacatg
cctgaagtggacttatatggcaccgttcagcctcacaccctgatccggcagcatattgat
tatggacattggtatgatagacagaaggtgatgcttaaagaaatccataactgccagtat
gtcgcctgcatgaatccgatggtgggcagcttcaccatcaatcccaggctacagagacat
ttcacagtgtttgcattcaattttccatctttggatgcactaaacaccatctatggccaa
atctttagcttccatttccaacagcaagcatttgctccatcaattctcaggagtggcccc
actttgatccaggcaacaatagcattccatcagacaatgatgtgtaactttttacccacg
gctattaaattccactacatctttaatctgagagatttatcaaacgtcttccaggggatt
ttatttgcttctcctgagtgtttaaaaggtccacttgatttaatacatctgtggcttcat
gaatctgcccgtgtttatggagacaaactgatagacaaaaaagattgtgatttgtttcag
agaagaatgctggaaactgcttataaatattttgaaggtatagatagtcacatgctgctt
caacagcccctcatttattgccactttgctgatagagggaaggacccacattacatgcca
gtgaaggactgggaagtgctgaagacgattcttacagaaacgttagacaactacaatgaa
ctaaatgctgccatgcacctagttttgtttgaagatgccatgcaacatgtgtgtcgcatc
agccggatcttacgaacccctcagggctgtgctctcttggttggagttgggggcagtggc
aagcagagcttgtccaggctggcagcttaccttcgtggccttgaggtctttcagatcact
ctgaccgagggctatggaatccaggaacttcgggtagatcttgccaatttgtacatccga
actggagccaagaacatgcccactgtgttcctgctgacagatgcccaggttctagatgag
agcttcctcgtgctgattaatgacttgctggcatcaggagaaatcccagatctgttcagc
gatgaagatgtggacaagataatttctggaattcataatgaagttcatgctctgggcatg
gtagactccagggaaaactgttggaaattctttatggccagggtgcgactacagctcaaa
atcattttgtgtttctctccagttggtcgcacgctgagagttagagctcggaagttccca
gccatagttaactgcacggctattgactggtttcatgcgtggccgcaggaggctctggtc
tccgtcagcaggaggttcattgaggaaaccaagggaattgagccagtgcacaaagactct
attagccttttcatggcacatgttcacaccactgtaaatgaaatgagtaccagatattac
cagaatgagagaagacacaactataccaccccaaagagttttctagaacaaatatcactg
tttaagaacctgttgaagaagaagcaaaatgaggtatccgagaaaaaagaacgcctggtg
aacggcatccaaaagctaaaaaccacagcctctcaggtgggagatctaaaagccagactt
gcctctcaagaagccgagctgcaactgagaaatcatgatgccgaagctctgatcacaaag
atcggccttcagacggagaaagtgagccgggaaaagaccatcgctgatgctgaggagcga
aaggtgacagccattcagactgaagtgttccagaaacagagagaatgtgaagctgactta
ctcaaggctgagcctgcactggtggctgctacagctgcactcaatacactcaacagggtc
aacctcagtgagctgaaagcctttcccaaccctcccatcgcagttaccaatgttactgca
gccgtgatggtccttctggctcctcggggaagagtgcccaaagaccgaagttggaaagca
gctaaagtcttcatgggaaaggttgatgattttttgcaagcattaattaactatgacaaa
gagcacattccagagaactgtctaaaagtggtgaatgaacactatttgaaagacccagag
tttaatccaaacctgattcgaaccaaatcttttgcagcagctggcctgtgtgcctgggtc
atcaacatcattaaattctatgaggtctactgtgatgtggagccaaaacgccaagcatta
gcccaagcaaacttagaactggctgcagctactgaaaaactagaggctatcaggaaaaag
cttgtggatctggatcgaaatctgagcagactcacggcttcatttgaaaaagcaacagct
gagaaagtccggtgtcaagaagaggtgaaccaaaccaacaaaaccatcaaattagctaac
agacttgtcaaggaacttgaggcaaagaagattcgctggggtcaatccattaagtccttt
gaagctcaagagaagacactctgtggagatgttcttctcacggcggcatttgtgtcttac
gtcggacccttcacaaggcagtatcgccaggagctggtgcactgcaagtgggttcccttt
cttcaacagaaggtttccattccactaaccgaaggcctggacttgatatccatgttgacg
gatgatgctacaattgccgcctggaataacgaaggactgcccagtgacagaatgtccacc
gaaaatgccgctatcctaacacactgtgagcgctggcctctggtgatagatccccagcaa
cagggaattaagtggatcaagaataagtatggaatggacctgaaagtcacacatttgggc
cagaaagggtttttgaatgccattgaaactgctttggcctttggtgatgtcatcttaatt
gaaaatctcgaggaaacgatagatccagtcctggatccactacttggcaggaacacaatt
aaaaaaggaaagtatatcaggattggagataaagaatgtgaatttaacaagaactttcgc
cttatccttcacacaaaattggcaaatcctcactataagccggaattacaagctcagaca
actctcctcaatttcacagtcacagaagatggtctagaagcccagctgctggcagaggtt
gtcagtattgaaaggccagatttggagaaacttaagttggtattgacaaagcaccaaaat
gattttaaaattgagctcaagtatctggaagacgatctccttttgcgcctttctgcggca
gagggaagctttctggatgacaccaaactggtagagagattggaggcaacaaagaccacc
gtggcagagatagagcacaaggtgattgaagccaaagaaaatgaaagaaaaatcaacgag
gcccgagaatgttacagaccagtggcagcaagagcatctcttctttattttgttattaat
gacctccaaaaaatcaaccccctctaccaattctctttgaaggcttttaacgtgctgttc
cacagagcgatcgagcaggctgacaaggtggaagacatgcagggacgcatctctatcctg
atggagagcatcacccatgctgtcttcctctacaccagccaggcgctgtttgagaaggac
aagctcaccttcctgtcccagatggcttttcagattttgttgagaaagaaagagatagac
cctcttgaattggatttcctgcttcgattcacagttgaacacactcatctgagtcccgtt
gacttcctaacttctcagtcatggagtgctatcaaggcaattgccgtcatggaagaattt
cgaggcatagaccgagatgtggaaggatctgccaagcagtggaggaagtgggtagaatcc
gagtgtccagaaaaagaaaaattacctcaagaatggaagaagaaaagtttaatacagaag
ctgattcttctgagagcaatgcgccctgacagaatgacgtatgctctcagaaattttgta
gaggaaaaactgggtgcgaagtatgtggagaggaccagattggacttagttaaagcattc
gaagaaagcagcccagccacccccatattcttcatcctgtctccgggggtagatgccctt
aaagacctggagattcttggcaaaagacttggctttacaattgactctggaaaattccac
aatgtgtctttaggacaaggtcaggagacggtggcagaagtggccctggagaaagcttcc
aaaggaggacactgggtcatcctccaaaatgttcatttggtagccaagtggctaggaacc
ttggagaagctccttgaaagattcagccaaggaagccacagagattacagggttttcatg
agtgctgagtctgcacctacaccagatgagcatatcatccctcaaggactcctggaaaat
tccattaagatcactaatgaacccccaacagggatgctggccaatttgcatgccgccctg
tacaactttgatcaggatacacttgaaatatgctccaaggagcaggagtttaaaagcatc
cttttttctctctgctacttccacgcctgtgttgctgggagactgaggtttggcccccag
ggctggagccgaagctatccttttaatcctggagacctcaccatttgtgccagtgtcctc
tacaactacttagaggcaaactctaaagtcccatgggaagatctccgttatctctttggt
gagatcatgtatggaggccacatcacagatgactgggatcgcaaactgtgtcgggtgtat
ttagaagaattcatgaatccatctctgactgaagatgaactgatgctggcaccaggtttt
gctgccccaccctacctagattatgcaggctaccaccagtacatagaggagatgcttcct
ccagaaagcccggcactgtatggcctccacccaaatgctgaaatagaattcctgacagtg
acatccaacactctcttcagaactttgctggagatgcagcccaggaatgcactcagtggt
gatgaactggggcagtctacagaagaaaaggttaagaatgtcttggatgacattttggag
aaacttccagaagagttcaacatggcagagataatgcaaaaaaattcaaatagaagccca
tatgttcttgtttgcttccaagaatgtgagaggatgaatattctcattcgggaaatacgt
atatcacttgaacaactggaccttagtttgaagggggaattggcattatctcctgctgtg
gaagcccagcagtttgcattgagttatgacacggtaccagacacttggagcaaactggct
tatccttctacttatggcctagcccagtggttcaatgacctcctcctgcgatgccgagaa
ctcgatacttggacacaagaccttacccttccggctgtcgtgtggctctccggcttcttc
aaccctcagtccttcttaactgcaatcatgcagacgatggctcgaaaaaatgagtggccc
ctggataaaacgcgcttgactgctgatgttaccaaaaaaacaaaggaagattatggacac
ccgccaagggaaggtgcatacctccacggactcttcatggagggcgcccgctgggacacc
caagcaggaaccattgttgaagcccgtctcaaggagctggcatgccctatgccggtcatc
tttgcaaaagccacccccgtggacagacaagaaaccaaacagacctacgagtgccctgtg
tatagaaccaaactgagaggccccagctacatctggaccttcaggctgaagagcgaagag
aagactgcaaaatgggttctggctggagtggctctgcttctagaagcgtaa

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