KEGG   Homo sapiens (human): 10146
Entry
10146             CDS       T01001                                 
Symbol
G3BP1, G3BP, HDH-VIII
Name
(RefSeq) G3BP stress granule assembly factor 1
  KO
K17265  Ras GTPase-activating protein-binding protein 1 [EC:5.6.2.5 5.6.2.3]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04623  Cytosolic DNA-sensing pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    10146 (G3BP1)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    10146 (G3BP1)
Enzymes [BR:hsa01000]
 5. Isomerases
  5.6  Isomerases altering macromolecular conformation
   5.6.2  Enzymes altering nucleic acid conformation
    5.6.2.3  DNA 5'-3' helicase
     10146 (G3BP1)
    5.6.2.5  RNA 5'-3' helicase
     10146 (G3BP1)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    Stress granule specific factors
     10146 (G3BP1)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   10146 (G3BP1)
SSDB
Motif
Pfam: NTF2 RRM_1 RRM_7 NXF_NTF2
Other DBs
NCBI-GeneID: 10146
NCBI-ProteinID: NP_005745
OMIM: 608431
HGNC: 30292
Ensembl: ENSG00000145907
UniProt: Q13283 Q5U0Q1 Q6ZP53
Structure
Position
5:151771954..151812785
AA seq 466 aa
MVMEKPSPLLVGREFVRQYYTLLNQAPDMLHRFYGKNSSYVHGGLDSNGKPADAVYGQKE
IHRKVMSQNFTNCHTKIRHVDAHATLNDGVVVQVMGLLSNNNQALRRFMQTFVLAPEGSV
ANKFYVHNDIFRYQDEVFGGFVTEPQEESEEEVEEPEERQQTPEVVPDDSGTFYDQAVVS
NDMEEHLEEPVAEPEPDPEPEPEQEPVSEIQEEKPEPVLEETAPEDAQKSSSPAPADIAQ
TVQEDLRTFSWASVTSKNLPPSGAVPVTGIPPHVVKVPASQPRPESKPESQIPPQRPQRD
QRVREQRINIPPQRGPRPIREAGEQGDIEPRRMVRHPDSHQLFIGNLPHEVDKSELKDFF
QSYGNVVELRINSGGKLPNFGFVVFDDSEPVQKVLSNRPIMFRGEVRLNVEEKKTRAARE
GDRRDNRLRGPGGPRGGLGGGMRGPPRGGMVQKPGFGVGRGLAPRQ
NT seq 1401 nt   +upstreamnt  +downstreamnt
atggtgatggagaagcctagtcccctgctggtcgggcgggaatttgtgagacagtattac
acactgctgaaccaggccccagacatgctgcatagattttatggaaagaactcttcttat
gtccatgggggattggattcaaatggaaagccagcagatgcagtctacggacagaaagaa
atccacaggaaagtgatgtcacaaaacttcaccaactgccacaccaagattcgccatgtt
gatgctcatgccacgctaaatgatggtgtggtagtccaggtgatggggcttctctctaac
aacaaccaggctttgaggagattcatgcaaacgtttgtccttgctcctgaggggtctgtt
gcaaataaattctatgttcacaatgatatcttcagataccaagatgaggtctttggtggg
tttgtcactgagcctcaggaggagtctgaagaagaagtagaggaacctgaagaaagacag
caaacacctgaggtggtacctgatgattctggaactttctatgatcaggcagttgtcagt
aatgacatggaagaacatttagaggagcctgttgctgaaccagagcctgatcctgaacca
gaaccagaacaagaacctgtatctgaaatccaagaggaaaagcctgagccagtattagaa
gaaactgcccctgaggatgctcagaagagttcttctccagcacctgcagacatagctcag
acagtacaggaagacttgaggacattttcttgggcatctgtgaccagtaagaatcttcca
cccagtggagctgttccagttactgggataccacctcatgttgttaaagtaccagcttca
cagccccgtccagagtctaagcctgaatctcagattccaccacaaagacctcagcgggat
caaagagtgcgagaacaacgaataaatattcctccccaaaggggacccagaccaatccgt
gaggctggtgagcaaggtgacattgaaccccgaagaatggtgagacaccctgacagtcac
caactcttcattggcaacctgcctcatgaagtggacaaatcagagcttaaagatttcttt
caaagttatggaaacgtggtggagttgcgcattaacagtggtgggaaattacccaatttt
ggttttgttgtgtttgatgattctgagcctgttcagaaagtccttagcaacaggcccatc
atgttcagaggtgaggtccgtctgaatgtcgaagagaagaagactcgagctgccagggaa
ggcgaccgacgagataatcgccttcggggacctggaggccctcgaggtgggctgggtggt
ggaatgagaggccctccccgtggaggcatggtgcagaaaccaggatttggagtgggaagg
gggcttgcgccacggcagtga

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (2)   
   KEGG ENZYME (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   RefGene (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (10)   
   OC (1)   
Protein sequence (6)   
   UniProt (3)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (40)   
   RefSeq(nuc) (2)   
   GenBank (19)   
   EMBL (19)   
3D Structure (15)   
   PDB (15)   
Protein domain (4)   
   Pfam (4)   
All databases (91)   

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