KEGG   Homo sapiens (human): 10273
Entry
10273             CDS       T01001                                 

Symbol
STUB1, CHIP, HSPABP2, NY-CO-7, SCA48, SCAR16, SDCCAG7, UBOX1
Name
(RefSeq) STIP1 homology and U-box containing protein 1
  KO
K09561  STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04120  Ubiquitin mediated proteolysis
hsa04141  Protein processing in endoplasmic reticulum
Disease
H01891  Autosomal recessive spinocerebellar ataxias
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    10273 (STUB1)
   04120 Ubiquitin mediated proteolysis
    10273 (STUB1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:hsa03110]
    10273 (STUB1)
   04131 Membrane trafficking [BR:hsa04131]
    10273 (STUB1)
   04121 Ubiquitin system [BR:hsa04121]
    10273 (STUB1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.27  RING-type E3 ubiquitin transferase
     10273 (STUB1)
Chaperones and folding catalysts [BR:hsa03110]
 Other chaperones and cochaperones
  Others
   10273 (STUB1)
Membrane trafficking [BR:hsa04131]
 Autophagy
  Aggrephagy
   Other aggrephagy associated proteins
    10273 (STUB1)
Ubiquitin system [BR:hsa04121]
 Ubiquitin ligases (E3)
  U-box type E3
   10273 (STUB1)
SSDB
Motif
Pfam: U-box CHIP_TPR_N TPR_1 TPR_2 ANAPC3 TPR_16 TPR_8 TPR_11 TPR_12 TPR_17 TPR_19 TPR_14 TPR_6 TPR_9 TPR_10 zf-NOSIP
Other DBs
NCBI-GeneID: 10273
NCBI-ProteinID: NP_005852
OMIM: 607207
HGNC: 11427
Ensembl: ENSG00000103266
Vega: OTTHUMG00000121140
Pharos: Q9UNE7(Tbio)
UniProt: Q9UNE7
Structure
PDB: 
6NSV 6EFK 4KBQ

Position
16p13.3
AA seq 303 aa
MKGKEEKEGGARLGAGGGSPEKSPSAQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVA
VYYTNRALCYLKMQQHEQALADCRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRA
YSLAKEQRLNFGDDIPSALRIAKKKRWNSIEERRIHQESELHSYLSRLIAAERERELEEC
QRNHEGDEDDSHVRAQQACIEAKHDKYMADMDELFSQVDEKRKKRDIPDYLCGKISFELM
REPCITPSGITYDRKDIEEHLQRVGHFDPVTRSPLTQEQLIPNLAMKEVIDAFISENGWV
EDY
NT seq 912 nt   +upstreamnt  +downstreamnt
atgaagggcaaggaggagaaggagggcggcgcacggctgggcgctggcggcggaagcccc
gagaagagcccgagcgcgcaggagctcaaggagcagggcaatcgtctgttcgtgggccga
aagtacccggaggcggcggcctgctacggccgcgcgatcacccggaacccgctggtggcc
gtgtattacaccaaccgggccttgtgctacctgaagatgcagcagcacgagcaggccctg
gccgactgccggcgcgccctggagctggacgggcagtctgtgaaggcgcacttcttcctg
gggcagtgccagctggagatggagagctatgatgaggccatcgccaatctgcagcgagct
tacagcctggccaaggagcagcggctgaacttcggggacgacatccccagcgctcttcga
atcgcgaagaagaagcgctggaacagcattgaggagcggcgcatccaccaggagagcgag
ctgcactcctacctctccaggctcattgccgcggagcgtgagagggagctggaagagtgc
cagcgaaaccacgagggtgatgaggacgacagccacgtccgggcccagcaggcctgcatt
gaggccaagcacgacaagtacatggcggacatggacgagcttttttctcaggtggatgag
aagaggaagaagcgagacatccccgactacctgtgtggcaagatcagctttgagctgatg
cgggagccgtgcatcacgcccagtggcatcacctacgaccgcaaggacatcgaggagcac
ctgcagcgtgtgggtcattttgaccccgtgacccggagccccctgacccaggaacagctc
atccccaacttggctatgaaggaggttattgacgcattcatctctgagaatggctgggtg
gaggactactga

  All links  
Ontology (5)   
   KEGG BRITE (5)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (4)   
   KEGG DISEASE (1)   
   OMIM (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (28)   
   KEGG ORTHOLOGY (1)   
   RefGene (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (19)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (20)   
   RefSeq(nuc) (2)   
   GenBank (9)   
   EMBL (9)   
Protein domain (16)   
   Pfam (16)   
All databases (81)   

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