KEGG   Homo sapiens (human): 10312
Entry
10312             CDS       T01001                                 
Symbol
TCIRG1, ATP6N1C, ATP6V0A3, Atp6i, OC-116kDa, OC116, OPTB1, Stv1, TIRC7, Vph1, a3
Name
(RefSeq) T cell immune regulator 1, ATPase H+ transporting V0 subunit a3
  KO
K02154  V-type H+-transporting ATPase subunit a
Organism
hsa  Homo sapiens (human)
Pathway
hsa00190  Oxidative phosphorylation
hsa01100  Metabolic pathways
hsa04142  Lysosome
hsa04145  Phagosome
hsa04721  Synaptic vesicle cycle
hsa04966  Collecting duct acid secretion
hsa05110  Vibrio cholerae infection
hsa05120  Epithelial cell signaling in Helicobacter pylori infection
hsa05152  Tuberculosis
hsa05165  Human papillomavirus infection
hsa05323  Rheumatoid arthritis
Module
hsa_M00160  V-type ATPase, eukaryotes
Disease
H00436  Osteopetrosis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    10312 (TCIRG1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    10312 (TCIRG1)
   04142 Lysosome
    10312 (TCIRG1)
 09150 Organismal Systems
  09155 Excretory system
   04966 Collecting duct acid secretion
    10312 (TCIRG1)
  09156 Nervous system
   04721 Synaptic vesicle cycle
    10312 (TCIRG1)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    10312 (TCIRG1)
  09171 Infectious disease: bacterial
   05110 Vibrio cholerae infection
    10312 (TCIRG1)
   05120 Epithelial cell signaling in Helicobacter pylori infection
    10312 (TCIRG1)
   05152 Tuberculosis
    10312 (TCIRG1)
  09163 Immune disease
   05323 Rheumatoid arthritis
    10312 (TCIRG1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    10312 (TCIRG1)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   10312 (TCIRG1)
SSDB
Motif
Pfam: V_ATPase_I APG6_N Romo1 DUF2730
Other DBs
NCBI-GeneID: 10312
NCBI-ProteinID: NP_006010
OMIM: 604592
HGNC: 11647
Ensembl: ENSG00000110719
Pharos: Q13488(Tbio)
UniProt: Q13488 A0A024R5E5
Position
11:68039025..68053762
AA seq 830 aa
MGSMFRSEEVALVQLFLPTAAAYTCVSRLGELGLVEFRDLNASVSAFQRRFVVDVRRCEE
LEKTFTFLQEEVRRAGLVLPPPKGRLPAPPPRDLLRIQEETERLAQELRDVRGNQQALRA
QLHQLQLHAAVLRQGHEPQLAAAHTDGASERTPLLQAPGGPHQDLRVNFVAGAVEPHKAP
ALERLLWRACRGFLIASFRELEQPLEHPVTGEPATWMTFLISYWGEQIGQKIRKITDCFH
CHVFPFLQQEEARLGALQQLQQQSQELQEVLGETERFLSQVLGRVLQLLPPGQVQVHKMK
AVYLALNQCSVSTTHKCLIAEAWCSVRDLPALQEALRDSSMEEGVSAVAHRIPCRDMPPT
LIRTNRFTASFQGIVDAYGVGRYQEVNPAPYTIITFPFLFAVMFGDVGHGLLMFLFALAM
VLAENRPAVKAAQNEIWQTFFRGRYLLLLMGLFSIYTGFIYNECFSRATSIFPSGWSVAA
MANQSGWSDAFLAQHTMLTLDPNVTGVFLGPYPFGIDPIWSLAANHLSFLNSFKMKMSVI
LGVVHMAFGVVLGVFNHVHFGQRHRLLLETLPELTFLLGLFGYLVFLVIYKWLCVWAARA
ASAPSILIHFINMFLFSHSPSNRLLYPRQEVVQATLVVLALAMVPILLLGTPLHLLHRHR
RRLRRRPADRQEENKAGLLDLPDASVNGWSSDEEKAGGLDDEEEAELVPSEVLMHQAIHT
IEFCLGCVSNTASYLRLWALSLAHAQLSEVLWAMVMRIGLGLGREVGVAAVVLVPIFAAF
AVMTVAILLVMEGLSAFLHALRLHWVEFQNKFYSGTGYKLSPFTFAATDD
NT seq 2493 nt   +upstreamnt  +downstreamnt
atgggctccatgttccggagcgaggaggtggccctggtccagctctttctgcccacagcg
gctgcctacacctgcgtgagtcggctgggcgagctgggcctcgtggagttcagagacctc
aacgcctcggtgagcgccttccagagacgctttgtggttgatgttcggcgctgtgaggag
ctggagaagaccttcaccttcctgcaggaggaggtgcggcgggctgggctggtcctgccc
ccgccaaaggggaggctgccggcacccccaccccgggacctgctgcgcatccaggaggag
acggagcgcctggcccaggagctgcgggatgtgcggggcaaccagcaggccctgcgggcc
cagctgcaccagctgcagctccacgccgccgtgctacgccagggccatgaacctcagctg
gcagccgcccacacagatggggcctcagagaggacgcccctgctccaggcccccgggggg
ccgcaccaggacctgagggtcaactttgtggcaggtgccgtggagccccacaaggcccct
gccctagagcgcctgctctggagggcctgccgcggcttcctcattgccagcttcagggag
ctggagcagccgctggagcaccccgtgacgggcgagccagccacgtggatgaccttcctc
atctcctactggggtgagcagatcggacagaagatccgcaagatcacggactgcttccac
tgccacgtcttcccgtttctgcagcaggaggaggcccgcctcggggccctgcagcagctg
caacagcagagccaggagctgcaggaggtcctcggggagacagagcggttcctgagccag
gtgctaggccgggtgctgcagctgctgccgccagggcaggtgcaggtccacaagatgaag
gccgtgtacctggccctgaaccagtgcagcgtgagcaccacgcacaagtgcctcattgcc
gaggcctggtgctctgtgcgagacctgcccgccctgcaggaggccctgcgggacagctcg
atggaggagggagtgagtgccgtggctcaccgcatcccctgccgggacatgccccccaca
ctcatccgcaccaaccgcttcacggccagcttccagggcatcgtggatgcctacggcgtg
ggccgctaccaggaggtcaaccccgctccctacaccatcatcaccttccccttcctgttt
gctgtgatgttcggggatgtgggccacgggctgctcatgttcctgttcgccctggccatg
gtccttgcggagaaccgaccggctgtgaaggccgcgcagaacgagatctggcagactttc
ttcaggggccgctacctgctcctgcttatgggcctgttctccatctacaccggcttcatc
tacaacgagtgcttcagtcgcgccaccagcatcttcccctcgggctggagtgtggccgcc
atggccaaccagtctggctggagtgatgcattcctggcccagcacacgatgcttaccctg
gatcccaacgtcaccggtgtcttcctgggaccctacccctttggcatcgatcctatttgg
agcctggctgccaaccacttgagcttcctcaactccttcaagatgaagatgtccgtcatc
ctgggcgtcgtgcacatggcctttggggtggtcctcggagtcttcaaccacgtgcacttt
ggccagaggcaccggctgctgctggagacgctgccggagctcaccttcctgctgggactc
ttcggttacctcgtgttcctagtcatctacaagtggctgtgtgtctgggctgccagggcc
gcctcggcccccagcatcctcatccacttcatcaacatgttcctcttctcccacagcccc
agcaacaggctgctctacccccggcaggaggtggtccaggccacgctggtggtcctggcc
ttggccatggtgcccatcctgctgcttggcacacccctgcacctgctgcaccgccaccgc
cgccgcctgcggaggaggcccgctgaccgacaggaggaaaacaaggccgggttgctggac
ctgcctgacgcatctgtgaatggctggagctccgatgaggaaaaggcagggggcctggat
gatgaagaggaggccgagctcgtcccctccgaggtgctcatgcaccaggccatccacacc
atcgagttctgcctgggctgcgtctccaacaccgcctcctacctgcgcctgtgggccctg
agcctggcccacgcccagctgtccgaggttctgtgggccatggtgatgcgcataggcctg
ggcctgggccgggaggtgggcgtggcggctgtggtgctggtccccatctttgccgccttt
gccgtgatgaccgtggctatcctgctggtgatggagggactctcagccttcctgcacgcc
ctgcggctgcactgggtggaattccagaacaagttctactcaggcacgggctacaagctg
agtcccttcaccttcgctgccacagatgactag

KEGG   Homo sapiens (human): 127124
Entry
127124            CDS       T01001                                 
Symbol
ATP6V1G3, ATP6G3, Vma10
Name
(RefSeq) ATPase H+ transporting V1 subunit G3
  KO
K02152  V-type H+-transporting ATPase subunit G
Organism
hsa  Homo sapiens (human)
Pathway
hsa00190  Oxidative phosphorylation
hsa01100  Metabolic pathways
hsa04145  Phagosome
hsa04150  mTOR signaling pathway
hsa04721  Synaptic vesicle cycle
hsa04966  Collecting duct acid secretion
hsa05110  Vibrio cholerae infection
hsa05120  Epithelial cell signaling in Helicobacter pylori infection
hsa05165  Human papillomavirus infection
hsa05323  Rheumatoid arthritis
Module
hsa_M00160  V-type ATPase, eukaryotes
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    127124 (ATP6V1G3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04150 mTOR signaling pathway
    127124 (ATP6V1G3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    127124 (ATP6V1G3)
 09150 Organismal Systems
  09155 Excretory system
   04966 Collecting duct acid secretion
    127124 (ATP6V1G3)
  09156 Nervous system
   04721 Synaptic vesicle cycle
    127124 (ATP6V1G3)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    127124 (ATP6V1G3)
  09171 Infectious disease: bacterial
   05110 Vibrio cholerae infection
    127124 (ATP6V1G3)
   05120 Epithelial cell signaling in Helicobacter pylori infection
    127124 (ATP6V1G3)
  09163 Immune disease
   05323 Rheumatoid arthritis
    127124 (ATP6V1G3)
SSDB
Motif
Pfam: V-ATPase_G RNase_Y_N FdhE OmpH T3SS_basalb_I
Other DBs
NCBI-GeneID: 127124
NCBI-ProteinID: NP_573569
OMIM: 618071
HGNC: 18265
Ensembl: ENSG00000151418
Pharos: Q96LB4(Tbio)
UniProt: Q96LB4
Position
1:complement(198523222..198540945)
AA seq 118 aa
MTSQSQGIHQLLQAEKRAKDKLEEAKKRKGKRLKQAKEEAMVEIDQYRMQRDKEFRLKQS
KIMGSQNNLSDEIEEQTLGKIQELNGHYNKYMESVMNQLLSMVCDMKPEIHVNYRATN
NT seq 357 nt   +upstreamnt  +downstreamnt
atgacaagccagtctcaggggatccaccagcttcttcaggcagaaaaacgggccaaggac
aagctagaggaagccaagaagagaaaaggaaagcgattgaagcaagccaaggaggaagca
atggtagaaattgaccagtacagaatgcagagagataaagagtttcgactaaaacaatct
aagataatgggctctcagaataatctctcagatgaaatagaagaacaaacactagggaag
atacaagaacttaatggacactacaataagtatatggaaagtgtgatgaaccagctcttg
agcatggtctgtgacatgaaaccagaaatccatgtgaactacagagccaccaactaa

KEGG   Homo sapiens (human): 155066
Entry
155066            CDS       T01001                                 
Symbol
ATP6V0E2, ATP6V0E2L, C7orf32
Name
(RefSeq) ATPase H+ transporting V0 subunit e2
  KO
K02153  V-type H+-transporting ATPase subunit e
Organism
hsa  Homo sapiens (human)
Pathway
hsa00190  Oxidative phosphorylation
hsa01100  Metabolic pathways
hsa04145  Phagosome
hsa04721  Synaptic vesicle cycle
hsa04966  Collecting duct acid secretion
hsa05110  Vibrio cholerae infection
hsa05120  Epithelial cell signaling in Helicobacter pylori infection
hsa05165  Human papillomavirus infection
hsa05323  Rheumatoid arthritis
Module
hsa_M00160  V-type ATPase, eukaryotes
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    155066 (ATP6V0E2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    155066 (ATP6V0E2)
 09150 Organismal Systems
  09155 Excretory system
   04966 Collecting duct acid secretion
    155066 (ATP6V0E2)
  09156 Nervous system
   04721 Synaptic vesicle cycle
    155066 (ATP6V0E2)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    155066 (ATP6V0E2)
  09171 Infectious disease: bacterial
   05110 Vibrio cholerae infection
    155066 (ATP6V0E2)
   05120 Epithelial cell signaling in Helicobacter pylori infection
    155066 (ATP6V0E2)
  09163 Immune disease
   05323 Rheumatoid arthritis
    155066 (ATP6V0E2)
SSDB
Motif
Pfam: ATP_synt_H DrsE_2 Far-17a_AIG1
Other DBs
NCBI-GeneID: 155066
NCBI-ProteinID: NP_660265
OMIM: 611019
HGNC: 21723
Ensembl: ENSG00000171130
Pharos: Q8NHE4(Tdark)
UniProt: Q8NHE4
Position
7:149872964..149880713
AA seq 81 aa
MTAHSFALPVIIFTTFWGLVGIAGPWFVPKGPNRGVIITMLVATAVCCYLFWLIAILAQL
NPLFGPQLKNETIWYVRFLWE
NT seq 246 nt   +upstreamnt  +downstreamnt
atgacggcgcactcattcgccctcccggtcatcatcttcaccacgttctggggcctcgtc
ggcatcgccgggccctggttcgtgccgaagggacccaaccgcggagtgatcatcaccatg
ctggtcgccaccgccgtctgctgttacctcttctggctcatcgccatcctggcgcagctg
aaccccctgttcgggccccagctgaagaatgagaccatctggtacgtgcgcttcctgtgg
gagtga

KEGG   Homo sapiens (human): 23545
Entry
23545             CDS       T01001                                 
Symbol
ATP6V0A2, A2, ARCL, ARCL2A, ATP6A2, ATP6N1D, J6B7, RTF, STV1, TJ6, TJ6M, TJ6S, VPH1, WSS, a2V
Name
(RefSeq) ATPase H+ transporting V0 subunit a2
  KO
K02154  V-type H+-transporting ATPase subunit a
Organism
hsa  Homo sapiens (human)
Pathway
hsa00190  Oxidative phosphorylation
hsa01100  Metabolic pathways
hsa04142  Lysosome
hsa04145  Phagosome
hsa04721  Synaptic vesicle cycle
hsa04966  Collecting duct acid secretion
hsa05110  Vibrio cholerae infection
hsa05120  Epithelial cell signaling in Helicobacter pylori infection
hsa05152  Tuberculosis
hsa05165  Human papillomavirus infection
hsa05323  Rheumatoid arthritis
Module
hsa_M00160  V-type ATPase, eukaryotes
Disease
H00557  Cutis laxa
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    23545 (ATP6V0A2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    23545 (ATP6V0A2)
   04142 Lysosome
    23545 (ATP6V0A2)
 09150 Organismal Systems
  09155 Excretory system
   04966 Collecting duct acid secretion
    23545 (ATP6V0A2)
  09156 Nervous system
   04721 Synaptic vesicle cycle
    23545 (ATP6V0A2)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    23545 (ATP6V0A2)
  09171 Infectious disease: bacterial
   05110 Vibrio cholerae infection
    23545 (ATP6V0A2)
   05120 Epithelial cell signaling in Helicobacter pylori infection
    23545 (ATP6V0A2)
   05152 Tuberculosis
    23545 (ATP6V0A2)
  09163 Immune disease
   05323 Rheumatoid arthritis
    23545 (ATP6V0A2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    23545 (ATP6V0A2)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   23545 (ATP6V0A2)
SSDB
Motif
Pfam: V_ATPase_I Takusan CENP-F_leu_zip
Other DBs
NCBI-GeneID: 23545
NCBI-ProteinID: NP_036595
OMIM: 611716
HGNC: 18481
Ensembl: ENSG00000185344
Pharos: Q9Y487(Tbio)
UniProt: Q9Y487
Position
12:123712353..123761755
AA seq 856 aa
MGSLFRSETMCLAQLFLQSGTAYECLSALGEKGLVQFRDLNQNVSSFQRKFVGEVKRCEE
LERILVYLVQEINRADIPLPEGEASPPAPPLKQVLEMQEQLQKLEVELREVTKNKEKLRK
NLLELIEYTHMLRVTKTFVKRNVEFEPTYEEFPSLESDSLLDYSCMQRLGAKLGFVSGLI
NQGKVEAFEKMLWRVCKGYTIVSYAELDESLEDPETGEVIKWYVFLISFWGEQIGHKVKK
ICDCYHCHVYPYPNTAEERREIQEGLNTRIQDLYTVLHKTEDYLRQVLCKAAESVYSRVI
QVKKMKAIYHMLNMCSFDVTNKCLIAEVWCPEADLQDLRRALEEGSRESGATIPSFMNII
PTKETPPTRIRTNKFTEGFQNIVDAYGVGSYREVNPALFTIITFPFLFAVMFGDFGHGFV
MFLFALLLVLNENHPRLNQSQEIMRMFFNGRYILLLMGLFSVYTGLIYNDCFSKSVNLFG
SGWNVSAMYSSSHPPAEHKKMVLWNDSVVRHNSILQLDPSIPGVFRGPYPLGIDPIWNLA
TNRLTFLNSFKMKMSVILGIIHMTFGVILGIFNHLHFRKKFNIYLVSIPELLFMLCIFGY
LIFMIFYKWLVFSAETSRVAPSILIEFINMFLFPASKTSGLYTGQEYVQRVLLVVTALSV
PVLFLGKPLFLLWLHNGRSCFGVNRSGYTLIRKDSEEEVSLLGSQDIEEGNHQVEDGCRE
MACEEFNFGEILMTQVIHSIEYCLGCISNTASYLRLWALSLAHAQLSDVLWAMLMRVGLR
VDTTYGVLLLLPVIALFAVLTIFILLIMEGLSAFLHAIRLHWVEFQNKFYVGAGTKFVPF
SFSLLSSKFNNDDSVA
NT seq 2571 nt   +upstreamnt  +downstreamnt
atggggtccctgttccggagcgagaccatgtgcctggcgcagctcttcctgcagtcgggc
acggcctacgagtgcctcagcgccctgggcgagaaaggcctggtccagttccgagacctc
aaccagaacgtaagttctttccaaagaaaatttgttggtgaggtgaagaggtgtgaagag
ctagagcgaatattggtgtatttggtacaggaaattaatagagctgatattccccttcct
gaaggagaggccagccctcctgcgccacccctgaaacaggttctagaaatgcaggagcag
ttgcagaagctcgaggttgaactgagagaagtcactaagaacaaggagaaactgaggaaa
aacttgctggaactgatagagtacactcacatgctgagagtgacaaagacctttgtgaaa
cgcaatgttgagtttgaacccacttatgaagaattcccttccttagagagtgattctttg
ttggattacagctgtatgcagaggctgggagcaaaactgggatttgtgtctggcctaatt
aaccaaggaaaagtggaagcatttgaaaaaatgttgtggagagtctgcaaagggtacacc
atcgtgtcctatgcagaactggatgaatcccttgaagaccctgaaacaggggaagtcata
aaatggtatgtctttttaatatccttttggggagagcagattggccacaaggttaagaag
atatgtgattgctaccactgccacgtgtacccctatccaaacacagccgaggagcggagg
gagatccaggaggggctgaacacccgcatccaggatctctacactgtactgcacaaaacc
gaggactatttgaggcaagtgctatgtaaagccgccgagtctgtctacagccgtgtgatc
caggtgaagaaaatgaaggccatctatcacatgctgaacatgtgcagctttgacgtgacc
aacaagtgcctcattgctgaggtctggtgtcccgaggcggatctgcaggacctgcgccgg
gcactggaggagggctcgagagagagtggtgctacaatcccctcattcatgaatataatc
cccacaaaagaaacaccccccactcggatccgcaccaacaaattcaccgagggatttcag
aacatcgtggatgcttatggagtcggaagctacagagaagtcaatccagctctctttacc
atcatcaccttcccgtttttatttgctgtgatgtttggagacttcggacatggctttgtg
atgtttttatttgccctcttgttggtgttaaatgaaaatcatcccagactaaatcagtca
caagagatcatgaggatgttttttaatggccggtacatcctcctgctgatggggctgttc
tcagtgtacactggcctcatctacaacgactgcttttcaaagtcagtcaacctgttcggc
tctgggtggaacgtgtcggccatgtacagctccagccacccacccgcagagcataagaag
atggtgctttggaatgacagcgtcgttagacacaacagcattttgcagctggatccaagc
attcctggagtgttccgaggcccttatccccttggcattgatcctatttggaacttggcc
acaaatcgcctcacttttctaaactctttcaaaatgaaaatgtccgtgattttaggaatc
attcatatgacttttggagtcattctgggaatatttaaccacttgcacttcaggaagaag
ttcaacatttacctggtttccatcccggaacttctcttcatgctctgtatctttggatac
cttatatttatgattttctacaagtggctggttttttcagcagaaacctccagagttgct
cccagcattctgattgaatttattaacatgtttttattcccagccagtaaaacaagtggc
ctttacacagggcaggagtatgtccagagagtgctgctggttgtcacagcattgtctgtc
cctgtcctcttcttgggaaagccactgtttttgttgtggcttcacaatgggcgtagttgc
ttcggggtgaaccggagtggctacacacttataaggaaagatagtgaggaagaagtttca
ttgctgggaagccaagatatagaagagggaaatcaccaggtggaagatggatgtagagaa
atggcgtgtgaagagtttaattttggagaaatattaatgacccaagtaatccattccatc
gagtactgtctgggatgcatctccaacaccgcctcctacctgaggctctgggcgcttagc
ctggctcacgcacagttgtctgatgtcctgtgggccatgctgatgcgcgtgggcctccgc
gttgacaccacctatggcgtcttgctactgctcccggttatcgcgctctttgcagttttg
accattttcatccttctgatcatggaagggctttctgcgtttcttcacgccatacgcctc
cactgggtagaatttcagaacaaattctacgttggtgcaggcaccaaatttgttcctttc
tcattcagtctactttcatcaaagttcaataacgacgacagtgtggcatga

KEGG   Homo sapiens (human): 245972
Entry
245972            CDS       T01001                                 
Symbol
ATP6V0D2, ATP6D2, VMA6
Name
(RefSeq) ATPase H+ transporting V0 subunit d2
  KO
K02146  V-type H+-transporting ATPase subunit d
Organism
hsa  Homo sapiens (human)
Pathway
hsa00190  Oxidative phosphorylation
hsa01100  Metabolic pathways
hsa04142  Lysosome
hsa04145  Phagosome
hsa04721  Synaptic vesicle cycle
hsa04966  Collecting duct acid secretion
hsa05110  Vibrio cholerae infection
hsa05120  Epithelial cell signaling in Helicobacter pylori infection
hsa05152  Tuberculosis
hsa05165  Human papillomavirus infection
hsa05203  Viral carcinogenesis
hsa05323  Rheumatoid arthritis
Module
hsa_M00160  V-type ATPase, eukaryotes
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    245972 (ATP6V0D2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    245972 (ATP6V0D2)
   04142 Lysosome
    245972 (ATP6V0D2)
 09150 Organismal Systems
  09155 Excretory system
   04966 Collecting duct acid secretion
    245972 (ATP6V0D2)
  09156 Nervous system
   04721 Synaptic vesicle cycle
    245972 (ATP6V0D2)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    245972 (ATP6V0D2)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    245972 (ATP6V0D2)
  09171 Infectious disease: bacterial
   05110 Vibrio cholerae infection
    245972 (ATP6V0D2)
   05120 Epithelial cell signaling in Helicobacter pylori infection
    245972 (ATP6V0D2)
   05152 Tuberculosis
    245972 (ATP6V0D2)
  09163 Immune disease
   05323 Rheumatoid arthritis
    245972 (ATP6V0D2)
SSDB
Motif
Pfam: vATP-synt_AC39
Other DBs
NCBI-GeneID: 245972
NCBI-ProteinID: NP_689778
OMIM: 618072
HGNC: 18266
Ensembl: ENSG00000147614
Pharos: Q8N8Y2(Tbio)
UniProt: Q8N8Y2 A0A024R991
Position
8:86098910..86154225
AA seq 350 aa
MLEGAELYFNVDHGYLEGLVRGCKASLLTQQDYINLVQCETLEDLKIHLQTTDYGNFLAN
HTNPLTVSKIDTEMRKRLCGEFEYFRNHSLEPLSTFLTYMTCSYMIDNVILLMNGALQKK
SVKEILGKCHPLGRFTEMEAVNIAETPSDLFNAILIETPLAPFFQDCMSENALDELNIEL
LRNKLYKSYLEAFYKFCKNHGDVTAEVMCPILEFEADRRAFIITLNSFGTELSKEDRETL
YPTFGKLYPEGLRLLAQAEDFDQMKNVADHYGVYKPLFEAVGGSGGKTLEDVFYEREVQM
NVLAFNRQFHYGVFYAYVKLKEQEIRNIVWIAECISQRHRTKINSYIPIL
NT seq 1053 nt   +upstreamnt  +downstreamnt
atgctcgaaggtgcggagctgtacttcaacgtggaccatggctacctggagggcctggtt
cgaggatgcaaggccagcctcctgacccagcaagactatatcaacctggtccagtgtgag
accctagaagacctgaaaattcatctccagactactgattatggtaactttttggctaat
cacacaaatcctcttactgtttccaaaattgacactgagatgaggaaaagactatgtgga
gaatttgagtatttccggaatcattccctggagcccctcagcacatttctcacctatatg
acgtgcagttatatgatagacaatgtgattctgctgatgaatggtgcattgcagaaaaaa
tctgtgaaagaaattctggggaagtgccaccccttgggccgtttcacagaaatggaagct
gtcaacattgcagagacaccttcagatctctttaatgccattctgatcgaaacgccatta
gctccattcttccaagactgcatgtctgaaaatgctctagatgaactgaatattgaattg
ctacgcaataaactatacaagtcttaccttgaggcattctataaattctgtaagaatcat
ggtgatgtcacagcagaagttatgtgtcccattcttgagtttgaggccgacagacgtgct
tttatcatcactcttaactcctttggcactgaattgagcaaagaagaccgagagaccctc
tatccaaccttcggcaaactctatcctgaggggttgcggctgttggctcaagcagaagac
tttgaccagatgaagaacgtagcggatcattacggagtatacaaacctttatttgaagct
gtaggtggcagtgggggaaagacattggaggacgtgttttacgagcgtgaggtacaaatg
aatgtgctggcattcaacagacagttccactacggtgtgttttatgcatatgtaaagctg
aaggaacaggaaattagaaatattgtgtggatagcagaatgtatttcacagaggcatcga
actaaaatcaacagttacattccaattttataa

KEGG   Homo sapiens (human): 245973
Entry
245973            CDS       T01001                                 
Symbol
ATP6V1C2, ATP6C2, VMA5
Name
(RefSeq) ATPase H+ transporting V1 subunit C2
  KO
K02148  V-type H+-transporting ATPase subunit C
Organism
hsa  Homo sapiens (human)
Pathway
hsa00190  Oxidative phosphorylation
hsa01100  Metabolic pathways
hsa04145  Phagosome
hsa04150  mTOR signaling pathway
hsa04721  Synaptic vesicle cycle
hsa04966  Collecting duct acid secretion
hsa05110  Vibrio cholerae infection
hsa05120  Epithelial cell signaling in Helicobacter pylori infection
hsa05165  Human papillomavirus infection
hsa05323  Rheumatoid arthritis
Module
hsa_M00160  V-type ATPase, eukaryotes
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    245973 (ATP6V1C2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04150 mTOR signaling pathway
    245973 (ATP6V1C2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    245973 (ATP6V1C2)
 09150 Organismal Systems
  09155 Excretory system
   04966 Collecting duct acid secretion
    245973 (ATP6V1C2)
  09156 Nervous system
   04721 Synaptic vesicle cycle
    245973 (ATP6V1C2)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    245973 (ATP6V1C2)
  09171 Infectious disease: bacterial
   05110 Vibrio cholerae infection
    245973 (ATP6V1C2)
   05120 Epithelial cell signaling in Helicobacter pylori infection
    245973 (ATP6V1C2)
  09163 Immune disease
   05323 Rheumatoid arthritis
    245973 (ATP6V1C2)
SSDB
Motif
Pfam: V-ATPase_C MetW Na_Ca_ex_C FliD_N Spc24 Cep57_MT_bd
Other DBs
NCBI-GeneID: 245973
NCBI-ProteinID: NP_001034451
OMIM: 618070
HGNC: 18264
Ensembl: ENSG00000143882
Pharos: Q8NEY4(Tbio)
UniProt: Q8NEY4
Position
2:10720943..10785110
AA seq 427 aa
MSEFWLISAPGDKENLQALERMNTVTSKSNLSYNTKFAIPDFKVGTLDSLVGLSDELGKL
DTFAESLIRRMAQSVVEVMEDSKGKVQEHLLANGVDLTSFVTHFEWDMAKYPVKQPLVSV
VDTIAKQLAQIEMDLKSRTAAYNTLKTNLENLEKKSMGNLFTRTLSDIVSKEDFVLDSEY
LVTLLVIVPKPNYSQWQKTYESLSDMVVPRSTKLITEDKEGGLFTVTLFRKVIEDFKTKA
KENKFTVREFYYDEKEIEREREEMARLLSDKKQQYQTSCVALKKGSSTFPDHKVKVTPLG
NPDRPAAGQTDRERESEGEGEGPLLRWLKVNFSEAFIAWIHIKALRVFVESVLRYGLPVN
FQAVLLQPHKKSSTKRLREVLNSVFRHLDEVAATSILDASVEIPGLQLNNQDYFPYVYFH
IDLSLLD
NT seq 1284 nt   +upstreamnt  +downstreamnt
atgtcggagttttggttaatttctgcccctggcgataaggaaaatttgcaagctctggag
aggatgaatactgtaacctccaagtccaacctgtcttataataccaaattcgctattcct
gacttcaaggtggggaccttggattccctggttggcctctctgatgagttggggaaactc
gacacctttgctgaaagcctcataaggagaatggctcagagcgtggtggaagtcatggag
gactcaaaggggaaggtccaggagcacctcctggcaaacggagttgacttaacatccttt
gtgacccactttgaatgggacatggccaaatatcctgtcaagcagccgctcgtgagtgtg
gtggacacaatagccaagcaactggcgcagatcgagatggacctgaagtcccgaacggcc
gcctacaacactctgaagacaaacctggagaacctggaaaagaaatccatggggaacctc
ttcacccggacactgagtgatattgtgagcaaagaggacttcgtgctggattctgaatat
ctcgtcacacttctggtcatcgtccccaaaccaaactactcacaatggcaaaaaacctac
gaatctctctcagacatggtggtccctcgatcaaccaaactcattactgaggacaaggaa
gggggccttttcactgtgactctgtttcgaaaagtgattgaagatttcaaaaccaaggcc
aaagaaaacaagttcactgttcgtgaattttactatgatgagaaggaaattgaaagggaa
agggaggagatggccagattgctgtctgataagaagcaacagtatcaaacttcctgtgtt
gctcttaaaaagggatcatccaccttcccggaccacaaggttaaggtaaccccgctaggt
aaccctgataggcctgctgcggggcagaccgacagagagagagagagtgagggcgagggt
gagggccccctgctgcgctggctcaaggtgaacttcagtgaagccttcattgcctggatc
cacatcaaggccctgagagtgtttgtggagtccgtgctcaggtatggactaccagtgaac
ttccaggcagtgctcctgcagccgcataagaagtcatccaccaagcgtttaagagaggtt
ctaaactctgtcttccgacatctggatgaagtagccgctacaagtatactggatgcatct
gtggagatcccgggactgcaactcaataaccaagactattttccttatgtctacttccat
attgaccttagtcttcttgactag

KEGG   Homo sapiens (human): 50617
Entry
50617             CDS       T01001                                 
Symbol
ATP6V0A4, A4, ATP6N1B, ATP6N2, DRTA3, RDRTA2, RTA1C, RTADR, STV1, VPH1, VPP2
Name
(RefSeq) ATPase H+ transporting V0 subunit a4
  KO
K02154  V-type H+-transporting ATPase subunit a
Organism
hsa  Homo sapiens (human)
Pathway
hsa00190  Oxidative phosphorylation
hsa01100  Metabolic pathways
hsa04142  Lysosome
hsa04145  Phagosome
hsa04721  Synaptic vesicle cycle
hsa04966  Collecting duct acid secretion
hsa05110  Vibrio cholerae infection
hsa05120  Epithelial cell signaling in Helicobacter pylori infection
hsa05152  Tuberculosis
hsa05165  Human papillomavirus infection
hsa05323  Rheumatoid arthritis
Module
hsa_M00160  V-type ATPase, eukaryotes
Disease
H00428  Distal renal tubular acidosis (RTA type 1)
H02310  Renal tubular acidosis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    50617 (ATP6V0A4)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    50617 (ATP6V0A4)
   04142 Lysosome
    50617 (ATP6V0A4)
 09150 Organismal Systems
  09155 Excretory system
   04966 Collecting duct acid secretion
    50617 (ATP6V0A4)
  09156 Nervous system
   04721 Synaptic vesicle cycle
    50617 (ATP6V0A4)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    50617 (ATP6V0A4)
  09171 Infectious disease: bacterial
   05110 Vibrio cholerae infection
    50617 (ATP6V0A4)
   05120 Epithelial cell signaling in Helicobacter pylori infection
    50617 (ATP6V0A4)
   05152 Tuberculosis
    50617 (ATP6V0A4)
  09163 Immune disease
   05323 Rheumatoid arthritis
    50617 (ATP6V0A4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    50617 (ATP6V0A4)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   50617 (ATP6V0A4)
SSDB
Motif
Pfam: V_ATPase_I Bacillus_HBL
Other DBs
NCBI-GeneID: 50617
NCBI-ProteinID: NP_065683
OMIM: 605239
HGNC: 866
Ensembl: ENSG00000105929
Pharos: Q9HBG4(Tbio)
UniProt: Q9HBG4 A0A024R791
Position
7:complement(138706294..138798196)
AA seq 840 aa
MVSVFRSEEMCLSQLFLQVEAAYCCVAELGELGLVQFKDLNMNVNSFQRKFVNEVRRCES
LERILRFLEDEMQNEIVVQLLEKSPLTPLPREMITLETVLEKLEGELQEANQNQQALKQS
FLELTELKYLLKKTQDFFETETNLADDFFTEDTSGLLELKAVPAYMTGKLGFIAGVINRE
RMASFERLLWRICRGNVYLKFSEMDAPLEDPVTKEEIQKNIFIIFYQGEQLRQKIKKICD
GFRATVYPCPEPAVERREMLESVNVRLEDLITVITQTESHRQRLLQEAAANWHSWLIKVQ
KMKAVYHILNMCNIDVTQQCVIAEIWFPVADATRIKRALEQGMELSGSSMAPIMTTVQSK
TAPPTFNRTNKFTAGFQNIVDAYGVGSYREINPAPYTIITFPFLFAVMFGDCGHGTVMLL
AALWMILNERRLLSQKTDNEIWNTFFHGRYLILLMGIFSIYTGLIYNDCFSKSLNIFGSS
WSVQPMFRNGTWNTHVMEESLYLQLDPAIPGVYFGNPYPFGIDPIWNLASNKLTFLNSYK
MKMSVILGIVQMVFGVILSLFNHIYFRRTLNIILQFIPEMIFILCLFGYLVFMIIFKWCC
FDVHVSQHAPSILIHFINMFLFNYSDSSNAPLYKHQQEVQSFFVVMALISVPWMLLIKPF
ILRASHRKSQLQASRIQEDATENIEGDSSSPSSRSGQRTSADTHGALDDHGEEFNFGDVF
VHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTMVMNSGLQTRGWGGIVGVFI
IFAVFAVLTVAILLIMEGLSAFLHALRLHWVEFQNKFYVGDGYKFSPFSFKHILDGTAEE
NT seq 2523 nt   +upstreamnt  +downstreamnt
atggtgtctgtgtttcgaagcgaggagatgtgtttgtcacaactgtttctccaggtggaa
gctgcatattgctgtgtggctgagctcggagagctcggattggttcagttcaaagattta
aatatgaatgtgaacagctttcaaaggaaatttgtgaatgaagtcagaaggtgtgaatca
ctggagagaatcctccgttttctggaagacgagatgcaaaatgagattgtagttcagttg
ctcgagaaaagcccactgaccccgctcccacgggaaatgattaccctggagactgttcta
gaaaaactggaaggagagttacaggaagccaaccagaaccagcaggccttgaaacaaagc
ttcctagaactgacagaactgaaatacctcctgaagaaaacccaagacttctttgagacg
gaaaccaatttagctgatgatttctttactgaggacacttctggcctcctggagttgaaa
gcagtgcctgcatatatgaccggaaagttggggttcatagccggtgtgatcaacagggag
aggatggcttcctttgagcggttactgtggcgaatctgccgaggaaacgtgtacttgaag
ttcagtgagatggacgcccctctggaggatcctgtgacgaaagaagaaattcagaagaac
atattcatcatattttaccaaggagagcagctcaggcagaaaatcaagaagatctgtgat
gggtttcgagccactgtctacccttgcccagagcctgcggtggagcgcagagagatgttg
gagagcgtcaatgtgaggctggaagatttaatcaccgtcataacacaaacagagtctcac
cgccagcgcctgctgcaggaagccgctgccaactggcactcctggctcatcaaggtgcag
aagatgaaagctgtctaccacatcctgaacatgtgcaacatcgacgtcacccagcagtgt
gtcatcgccgagatctggttcccggtggcagatgccacacgtatcaagagggcactggag
caaggcatggaactaagtggctcctccatggcccccatcatgaccacagtgcaatctaaa
acagcccctcccacatttaacaggaccaataaattcacagctggcttccagaatattgtt
gatgcctatggtgtcggcagctaccgggagataaacccagccccctacaccatcatcact
ttccccttcctgttcgctgtgatgtttggagactgtggtcatggaaccgtgatgctcctg
gctgcactttggatgattctgaatgagagacgcttgctctcccagaagacagacaatgag
atttggaacaccttcttccacgggcgctatctgatcctacttatgggcatcttctccatc
tacacgggtttgatctacaatgactgcttctccaagtccttgaacatctttggctcttct
tggagtgtccaacccatgttcagaaacggcacatggaatactcatgtaatggaggaaagt
ctatatctgcagctggacccagccataccaggagtgtattttggaaatccatacccgttt
gggattgatccgatttggaacttggcttcaaacaaactcacatttctgaactcgtataaa
atgaagatgtcggtgatcctgggaattgtccagatggttttcggtgtcatcctcagcctt
ttcaatcacatatacttcagaagaactctcaacatcattctgcaatttatccctgagatg
atttttatcctgtgtctgtttggatacctggttttcatgatcattttcaaatggtgctgc
tttgacgtccatgtatctcagcacgcccccagcatcctcatccacttcatcaacatgttt
ctgtttaactacagtgactcttccaacgcacccctctacaaacatcagcaagaagtccaa
agtttctttgtggttatggctttgatttctgtgccgtggatgcttctgattaagccgttt
attcttagagccagtcatcggaaatcccagctgcaggcatccaggatccaagaagatgcc
actgagaacattgaaggtgatagctccagcccttctagccgttctggccagaggacttct
gcagatacccacggggctctggacgaccatggagaagagttcaactttggagacgtcttt
gtccaccaagccatccacaccatcgagtactgcctgggctgcatttcaaacacagcctcc
tacctgcggctctgggccctcagcctggctcatgcacaactgtctgaagtgctctggact
atggtgatgaacagcggccttcagacgcgaggctggggaggaatcgtcggggtttttatt
atttttgccgtatttgctgtcctgacagtagccatccttctgatcatggagggcctctct
gctttcctgcacgccctgcgactgcactgggttgagttccagaacaagttctatgtcggg
gatggttacaagttttctccattctcctttaaacacatcctggatggcacagccgaggag
tag

KEGG   Homo sapiens (human): 51382
Entry
51382             CDS       T01001                                 
Symbol
ATP6V1D, ATP6M, VATD, VMA8
Name
(RefSeq) ATPase H+ transporting V1 subunit D
  KO
K02149  V-type H+-transporting ATPase subunit D
Organism
hsa  Homo sapiens (human)
Pathway
hsa00190  Oxidative phosphorylation
hsa01100  Metabolic pathways
hsa04145  Phagosome
hsa04150  mTOR signaling pathway
hsa04721  Synaptic vesicle cycle
hsa04966  Collecting duct acid secretion
hsa05110  Vibrio cholerae infection
hsa05120  Epithelial cell signaling in Helicobacter pylori infection
hsa05165  Human papillomavirus infection
hsa05323  Rheumatoid arthritis
Module
hsa_M00160  V-type ATPase, eukaryotes
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    51382 (ATP6V1D)
 09130 Environmental Information Processing
  09132 Signal transduction
   04150 mTOR signaling pathway
    51382 (ATP6V1D)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    51382 (ATP6V1D)
 09150 Organismal Systems
  09155 Excretory system
   04966 Collecting duct acid secretion
    51382 (ATP6V1D)
  09156 Nervous system
   04721 Synaptic vesicle cycle
    51382 (ATP6V1D)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    51382 (ATP6V1D)
  09171 Infectious disease: bacterial
   05110 Vibrio cholerae infection
    51382 (ATP6V1D)
   05120 Epithelial cell signaling in Helicobacter pylori infection
    51382 (ATP6V1D)
  09163 Immune disease
   05323 Rheumatoid arthritis
    51382 (ATP6V1D)
SSDB
Motif
Pfam: ATP-synt_D
Other DBs
NCBI-GeneID: 51382
NCBI-ProteinID: NP_057078
OMIM: 609398
HGNC: 13527
Ensembl: ENSG00000100554
Pharos: Q9Y5K8(Tbio)
UniProt: Q9Y5K8 A0A024R683
Structure
Position
14:complement(67337872..67359804)
AA seq 247 aa
MSGKDRIEIFPSRMAQTIMKARLKGAQTGRNLLKKKSDALTLRFRQILKKIIETKMLMGE
VMREAAFSLAEAKFTAGDFSTTVIQNVNKAQVKIRAKKDNVAGVTLPVFEHYHEGTDSYE
LTGLARGGEQLAKLKRNYAKAVELLVELASLQTSFVTLDEAIKITNRRVNAIEHVIIPRI
ERTLAYIITELDEREREEFYRLKKIQEKKKILKEKSEKDLEQRRAAGEVLEPANLLAEEK
DEDLLFE
NT seq 744 nt   +upstreamnt  +downstreamnt
atgtcgggcaaagaccgaattgaaatctttccctcgcgaatggcacagaccatcatgaag
gctcgtttaaagggagcacagacaggtcgaaacctcctgaagaaaaaatctgatgcctta
actcttcgatttcgacagatcctaaagaagataatagagactaaaatgttgatgggcgaa
gtgatgagagaagctgccttttcactagctgaagccaagttcacagcaggtgacttcagc
actacagttatccaaaatgtcaataaagcgcaagtgaagattcgagcgaagaaagataat
gtagcaggtgttactttgccagtatttgaacattaccatgaaggaactgacagttatgaa
ctgactggtttagccagaggtggggaacagttggctaaattaaagaggaattatgccaaa
gcagtggaactactggtggaactagcttctctgcagacttcttttgttactttggatgaa
gctattaagataaccaacaggcgtgtaaatgccattgaacatgtcatcattccccggatt
gaacgtactcttgcttatatcatcacagagctggatgagagagagcgagaagagttctat
aggttaaagaaaatacaagagaagaaaaagattctaaaggaaaaatctgagaaggacttg
gagcaaaggagagcagctggagaggtgttggagcctgctaatcttctggctgaagagaag
gacgaggatcttctatttgaataa

KEGG   Homo sapiens (human): 51606
Entry
51606             CDS       T01001                                 
Symbol
ATP6V1H, CGI-11, MSTP042, NBP1, SFD, SFDalpha, SFDbeta, VMA13
Name
(RefSeq) ATPase H+ transporting V1 subunit H
  KO
K02144  V-type H+-transporting ATPase subunit H
Organism
hsa  Homo sapiens (human)
Pathway
hsa00190  Oxidative phosphorylation
hsa01100  Metabolic pathways
hsa04142  Lysosome
hsa04145  Phagosome
hsa04150  mTOR signaling pathway
hsa04721  Synaptic vesicle cycle
hsa05110  Vibrio cholerae infection
hsa05120  Epithelial cell signaling in Helicobacter pylori infection
hsa05152  Tuberculosis
hsa05165  Human papillomavirus infection
hsa05323  Rheumatoid arthritis
Module
hsa_M00160  V-type ATPase, eukaryotes
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    51606 (ATP6V1H)
 09130 Environmental Information Processing
  09132 Signal transduction
   04150 mTOR signaling pathway
    51606 (ATP6V1H)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    51606 (ATP6V1H)
   04142 Lysosome
    51606 (ATP6V1H)
 09150 Organismal Systems
  09156 Nervous system
   04721 Synaptic vesicle cycle
    51606 (ATP6V1H)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    51606 (ATP6V1H)
  09171 Infectious disease: bacterial
   05110 Vibrio cholerae infection
    51606 (ATP6V1H)
   05120 Epithelial cell signaling in Helicobacter pylori infection
    51606 (ATP6V1H)
   05152 Tuberculosis
    51606 (ATP6V1H)
  09163 Immune disease
   05323 Rheumatoid arthritis
    51606 (ATP6V1H)
SSDB
Motif
Pfam: V-ATPase_H_N V-ATPase_H_C Arm Arm_2 Adaptin_N HEAT DUF2326 MCAfunc UCH
Other DBs
NCBI-GeneID: 51606
NCBI-ProteinID: NP_057025
OMIM: 608861
HGNC: 18303
Ensembl: ENSG00000047249
Pharos: Q9UI12(Tbio)
UniProt: Q9UI12 A0A024R7U9
Structure
Position
8:complement(53715543..53843245)
AA seq 483 aa
MTKMDIRGAVDAAVPTNIIAAKAAEVRANKVNWQSYLQGQMISAEDCEFIQRFEMKRSPE
EKQEMLQTEGSQCAKTFINLMTHICKEQTVQYILTMVDDMLQENHQRVSIFFDYARCSKN
TAWPYFLPMLNRQDPFTVHMAARIIAKLAAWGKELMEGSDLNYYFNWIKTQLSSQKLRGS
GVAVETGTVSSSDSSQYVQCVAGCLQLMLRVNEYRFAWVEADGVNCIMGVLSNKCGFQLQ
YQMIFSIWLLAFSPQMCEHLRRYNIIPVLSDILQESVKEKVTRIILAAFRNFLEKSTERE
TRQEYALAMIQCKVLKQLENLEQQKYDDEDISEDIKFLLEKLGESVQDLSSFDEYSSELK
SGRLEWSPVHKSEKFWRENAVRLNEKNYELLKILTKLLEVSDDPQVLAVAAHDVGEYVRH
YPRGKRVIEQLGGKQLVMNHMHHEDQQVRYNALLAVQKLMVHNWEYLGKQLQSEQPQTAA
ARS
NT seq 1452 nt   +upstreamnt  +downstreamnt
atgaccaaaatggatatccgaggtgctgtggatgctgctgtccccaccaatattattgct
gccaaggctgcagaagttcgtgcaaacaaagtcaactggcaatcctatcttcagggacag
atgatttctgctgaagattgtgagtttattcagaggtttgaaatgaaacgaagccctgaa
gagaagcaagagatgcttcaaactgaaggcagccagtgtgctaaaacatttataaatctg
atgactcatatctgcaaagaacagaccgttcagtatatactaactatggtggatgatatg
ctgcaggaaaatcatcagcgtgttagcattttctttgactatgcaagatgtagcaagaac
actgcgtggccctactttctgccaatgttgaatcgccaggatcccttcactgttcatatg
gcagcaagaattattgccaagttagcagcttggggaaaagaactgatggaaggcagtgac
ttaaattactatttcaattggataaaaactcagctgagttcacagaaactgcgtggtagc
ggtgttgctgttgaaacaggaacagtctcttcaagtgatagttcgcagtatgtgcagtgc
gtggccgggtgtttgcagctgatgctccgggtcaatgagtaccgctttgcttgggtggaa
gcagatggggtaaattgcataatgggagtgttgagtaacaagtgtggctttcagctccag
tatcaaatgattttttcaatatggctcctggcattcagtcctcaaatgtgtgaacacctg
cggcgctataatatcattccagttctgtctgatatccttcaggagtctgtcaaagagaaa
gtaacaagaatcattcttgcagcatttcgtaactttttagaaaaatcaactgaaagagaa
actcgccaagaatatgccctggctatgattcagtgcaaagttctgaaacagttggagaac
ttggaacagcagaagtacgatgatgaagatatcagcgaagatatcaaatttcttttggaa
aaacttggagagagtgtccaggaccttagttcatttgatgaatacagttcagaacttaaa
tctggaaggttggaatggagtcctgtgcacaaatctgagaaattttggagagagaatgct
gtgaggttaaatgagaagaattatgaactcttgaaaatcttgacaaaacttttggaagtg
tcagatgatccccaagtcttagctgttgctgctcacgatgttggagaatatgtgcggcat
tatccacgaggcaaacgggtcatcgagcagctcggtgggaagcagctggtcatgaaccac
atgcatcatgaagaccagcaggtccgctataatgctctgctggccgtgcagaagctcatg
gtgcacaactgggaataccttggcaagcagctccagtccgagcagccccagaccgctgcc
gcccgaagctaa

KEGG   Homo sapiens (human): 523
Entry
523               CDS       T01001                                 
Symbol
ATP6V1A, ARCL2D, ATP6A1, ATP6V1A1, DEE93, HO68, IECEE3, VA68, VPP2, Vma1
Name
(RefSeq) ATPase H+ transporting V1 subunit A
  KO
K02145  V-type H+-transporting ATPase subunit A [EC:7.1.2.2]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00190  Oxidative phosphorylation
hsa01100  Metabolic pathways
hsa04145  Phagosome
hsa04150  mTOR signaling pathway
hsa04721  Synaptic vesicle cycle
hsa04966  Collecting duct acid secretion
hsa05110  Vibrio cholerae infection
hsa05120  Epithelial cell signaling in Helicobacter pylori infection
hsa05165  Human papillomavirus infection
hsa05323  Rheumatoid arthritis
Module
hsa_M00160  V-type ATPase, eukaryotes
Disease
H00557  Cutis laxa
H00606  Early infantile epileptic encephalopathy
H02150  Infantile or early childhood epileptic encephalopathy
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    523 (ATP6V1A)
 09130 Environmental Information Processing
  09132 Signal transduction
   04150 mTOR signaling pathway
    523 (ATP6V1A)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    523 (ATP6V1A)
 09150 Organismal Systems
  09155 Excretory system
   04966 Collecting duct acid secretion
    523 (ATP6V1A)
  09156 Nervous system
   04721 Synaptic vesicle cycle
    523 (ATP6V1A)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    523 (ATP6V1A)
  09171 Infectious disease: bacterial
   05110 Vibrio cholerae infection
    523 (ATP6V1A)
   05120 Epithelial cell signaling in Helicobacter pylori infection
    523 (ATP6V1A)
  09163 Immune disease
   05323 Rheumatoid arthritis
    523 (ATP6V1A)
Enzymes [BR:hsa01000]
 7. Translocases
  7.1  Catalysing the translocation of hydrons
   7.1.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.1.2.2  H+-transporting two-sector ATPase
     523 (ATP6V1A)
SSDB
Motif
Pfam: ATP-synt_ab ATP-synt_ab_Xtn ATP-synt_ab_N
Other DBs
NCBI-GeneID: 523
NCBI-ProteinID: NP_001681
OMIM: 607027
HGNC: 851
Ensembl: ENSG00000114573
Pharos: P38606(Tbio)
UniProt: P38606
Structure
Position
3:113747035..113812056
AA seq 617 aa
MDFSKLPKILDEDKESTFGYVHGVSGPVVTACDMAGAAMYELVRVGHSELVGEIIRLEGD
MATIQVYEETSGVSVGDPVLRTGKPLSVELGPGIMGAIFDGIQRPLSDISSQTQSIYIPR
GVNVSALSRDIKWDFTPCKNLRVGSHITGGDIYGIVSENSLIKHKIMLPPRNRGTVTYIA
PPGNYDTSDVVLELEFEGVKEKFTMVQVWPVRQVRPVTEKLPANHPLLTGQRVLDALFPC
VQGGTTAIPGAFGCGKTVISQSLSKYSNSDVIIYVGCGERGNEMSEVLRDFPELTMEVDG
KVESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYHVSMMADSTSRWAEALRE
ISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGNPEREGSVSIVGAVSPPGGDFSDP
VTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYMRALDEYYDKHFTEFVPLRTKAK
EILQEEEDLAEIVQLVGKASLAETDKITLEVAKLIKDDFLQQNGYTPYDRFCPFYKTVGM
LSNMIAFYDMARRAVETTAQSDNKITWSIIREHMGDILYKLSSMKFKDPLKDGEAKIKSD
YAQLLEDMQNAFRSLED
NT seq 1854 nt   +upstreamnt  +downstreamnt
atggatttttccaagctacccaaaatactcgatgaagataaagaaagcacatttggttat
gtgcatggggtctcaggacctgtggttacagcctgtgacatggcgggtgcagccatgtat
gagctggtgagagtgggccacagcgaattggttggagagattattcgattggagggtgac
atggctactattcaggtgtatgaagaaacttctggtgtgtctgttggagatcctgtactt
cgcactggtaaacccctctctgtagagcttggtcctggcattatgggagccatttttgat
ggtattcaaagacctttgtcggatatcagcagtcagacccaaagcatctacatccccaga
ggagtaaacgtgtctgctcttagcagagatatcaaatgggactttacaccttgcaaaaac
ctacgggttggtagtcatatcactggcggagacatttatggaattgtcagtgagaactcg
cttatcaaacacaaaatcatgttacccccacgaaacagaggaactgtaacttacattgct
ccacctgggaattatgatacctctgatgttgtcttggagcttgaatttgaaggtgtaaag
gagaagttcaccatggtgcaagtatggcctgtacgtcaagttcgacctgtcactgagaag
ctgccagccaatcatcctctgttgactggccagagagtccttgatgccctttttccgtgt
gtccagggaggaactactgctatccctggagcctttggctgtggaaagacagtgatatca
cagtctctatccaagtattctaacagtgatgtaatcatctatgtaggatgtggtgaaaga
ggaaatgagatgtctgaagtcctccgggacttcccagagctcacaatggaggttgatggt
aaggtagagtcaattatgaagaggacagctttggtagccaatacctccaatatgcctgtt
gctgctagagaagcctctatttatactggaatcacactgtcagagtacttccgtgacatg
ggctatcatgtcagtatgatggctgactctacctctagatgggctgaggcccttagagaa
atctctggtcgtttagctgaaatgcctgcagatagtggatatccagcctatcttggtgcc
cgtctggcctcgttttatgaacgagcaggcagggtgaaatgtcttggaaatcctgaaaga
gaagggagtgtcagcattgtaggagcagtttctccacctggtggtgatttttctgatcca
gttacatctgccactcttggtatcgttcaggtgttctggggcttagataagaaactagct
caacgtaagcatttcccctctgtcaattggctcatcagctacagcaagtatatgcgtgcc
ttggatgaatactatgacaaacacttcacagagttcgttcctctgaggacgaaagctaag
gaaattctgcaggaagaagaagacctggcagaaattgtacagcttgtgggaaaggcttct
ttggcagaaacagataaaatcactctggaggtagcaaaacttatcaaagatgatttccta
caacaaaatggatatactccttatgacaggttctgcccattctacaagacagtagggatg
ctgtccaacatgattgcattttatgatatggctcgtagagctgttgaaaccactgcccag
agtgacaataaaatcacatggtccattattcgtgagcacatgggagacatcctctataaa
ctttcctccatgaaattcaaggatccactgaaagatggtgaggcaaagatcaaaagcgac
tatgcacaacttcttgaagacatgcagaatgcattccgtagccttgaagattag

DBGET integrated database retrieval system