KEGG   Homo sapiens (human): 10320
Entry
10320             CDS       T01001                                 
Symbol
IKZF1, CVID13, Hs.54452, IK1, IKAROS, LYF1, LyF-1, PPP1R92, PRO0758, ZNFN1A1
Name
(RefSeq) IKAROS family zinc finger 1
  KO
K09220  IKAROS family zinc finger protein
Organism
hsa  Homo sapiens (human)
Disease
H00088  Common variable immunodeficiency
Drug target
Zelebrudomide: D12858
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    10320 (IKZF1)
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    10320 (IKZF1)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     10320 (IKZF1)
Transcription factors [BR:hsa03000]
 Eukaryotic type
  Zinc finger
   Cys2His2 others
    10320 (IKZF1)
SSDB
Motif
Pfam: zf-H2C2_2 zf-C2H2 zf-C2H2_4 zf-C2H2_16 DUF7128 zf-C2H2_REST zf-C2H2_11 zf-H2C2_5 GAGA
Other DBs
NCBI-GeneID: 10320
NCBI-ProteinID: NP_006051
OMIM: 603023
HGNC: 13176
Ensembl: ENSG00000185811
UniProt: Q13422 R9R4D9
Structure
Position
7:50303455..50405101
AA seq 519 aa
MDADEGQDMSQVSGKESPPVSDTPDEGDEPMPIPEDLSTTSGGQQSSKSDRVVASNVKVE
TQSDEENGRACEMNGEECAEDLRMLDASGEKMNGSHRDQGSSALSGVGGIRLPNGKLKCD
ICGIICIGPNVLMVHKRSHTGERPFQCNQCGASFTQKGNLLRHIKLHSGEKPFKCHLCNY
ACRRRDALTGHLRTHSVGKPHKCGYCGRSYKQRSSLEEHKERCHNYLESMGLPGTLYPVI
KEETNHSEMAEDLCKIGSERSLVLDRLASNVAKRKSSMPQKFLGDKGLSDTPYDSSASYE
KENEMMKSHVMDQAINNAINYLGAESLRPLVQTPPGGSEVVPVISPMYQLHKPLAEGTPR
SNHSAQDSAVENLLLLSKAKLVPSEREASPSNSCQDSTDTESNNEEQRSGLIYLTNHIAP
HARNGLSLKEEHRAYDLLRAASENSQDALRVVSTSGEQMKVYKCEHCRVLFLDHVMYTIH
MGCHGFRDPFECNMCGYHSQDRYEFSSHITRGEHRFHMS
NT seq 1560 nt   +upstreamnt  +downstreamnt
atggatgctgatgagggtcaagacatgtcccaagtttcagggaaggaaagcccccctgta
agcgatactccagatgagggcgatgagcccatgccgatccccgaggacctctccaccacc
tcgggaggacagcaaagctccaagagtgacagagtcgtggccagtaatgttaaagtagag
actcagagtgatgaagagaatgggcgtgcctgtgaaatgaatggggaagaatgtgcggag
gatttacgaatgcttgatgcctcgggagagaaaatgaatggctcccacagggaccaaggc
agctcggctttgtcgggagttggaggcattcgacttcctaacggaaaactaaagtgtgat
atctgtgggatcatttgcatcgggcccaatgtgctcatggttcacaaaagaagccacact
ggagaacggcccttccagtgcaatcagtgcggggcctcattcacccagaagggcaacctg
ctccggcacatcaagctgcattccggggagaagcccttcaaatgccacctctgcaactac
gcctgccgccggagggacgccctcactggccacctgaggacgcactccgttggtaaacct
cacaaatgtggatattgtggccgaagctataaacagcgaagctctttagaggaacataaa
gagcgctgccacaactacttggaaagcatgggccttccgggcacactgtacccagtcatt
aaagaagaaactaatcacagtgaaatggcagaagacctgtgcaagataggatcagagaga
tctctcgtgctggacagactagcaagtaacgtcgccaaacgtaagagctctatgcctcag
aaatttcttggggacaagggcctgtccgacacgccctacgacagcagcgccagctacgag
aaggagaacgaaatgatgaagtcccacgtgatggaccaagccatcaacaacgccatcaac
tacctgggggccgagtccctgcgcccgctggtgcagacgcccccgggcggttccgaggtg
gtcccggtcatcagcccgatgtaccagctgcacaagccgctcgcggagggcaccccgcgc
tccaaccactcggcccaggacagcgccgtggagaacctgctgctgctctccaaggccaag
ttggtgccctcggagcgcgaggcgtccccgagcaacagctgccaagactccacggacacc
gagagcaacaacgaggagcagcgcagcggtctcatctacctgaccaaccacatcgccccg
cacgcgcgcaacgggctgtcgctcaaggaggagcaccgcgcctacgacctgctgcgcgcc
gcctccgagaactcgcaggacgcgctccgcgtggtcagcaccagcggggagcagatgaag
gtgtacaagtgcgaacactgccgggtgctcttcctggatcacgtcatgtacaccatccac
atgggctgccacggcttccgtgatccttttgagtgcaacatgtgcggctaccacagccag
gaccggtacgagttctcgtcgcacataacgcgaggggagcaccgcttccacatgagctaa

  All links  
Disease (2)   
   OMIM (2)   
Gene (10)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (108)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (105)   
DNA sequence (162)   
   RefSeq(nuc) (112)   
   GenBank (25)   
   EMBL (25)   
3D Structure (7)   
   PDB (7)   
Protein domain (9)   
   Pfam (9)   
All databases (298)   

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