KEGG   Homo sapiens (human): 10450
Entry
10450             CDS       T01001                                 
Symbol
PPIE, CYP-33, CYP33, CypE
Name
(RefSeq) peptidylprolyl isomerase E
  KO
K09564  peptidyl-prolyl isomerase E (cyclophilin E) [EC:5.2.1.8]
Organism
hsa  Homo sapiens (human)
Pathway
hsa03040  Spliceosome
Network
nt06547  Spliceosome
  Element
N01971  spliceosome activation
N01972  Spliceosome catalysis (branching)
N01993  Spliceosome catalysis (exon ligation)
N01994  Spliceosome disassembly
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09121 Transcription
   03040 Spliceosome
    10450 (PPIE)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03041 Spliceosome [BR:hsa03041]
    10450 (PPIE)
   03110 Chaperones and folding catalysts [BR:hsa03110]
    10450 (PPIE)
Enzymes [BR:hsa01000]
 5. Isomerases
  5.2  cis-trans-Isomerases
   5.2.1  cis-trans Isomerases (only sub-subclass identified to date)
    5.2.1.8  peptidylprolyl isomerase
     10450 (PPIE)
Spliceosome [BR:hsa03041]
 Complex B
  Other components
   Prp19-related factors
    10450 (PPIE)
 Complex C
    10450 (PPIE)
Chaperones and folding catalysts [BR:hsa03110]
 Protein folding catalysts
  Peptidyl prolyl isomerase
   Cyclophilin
    10450 (PPIE)
SSDB
Motif
Pfam: Pro_isomerase RRM_1 RRM_5 RRM_occluded RRM_7 DUF4944
Other DBs
NCBI-GeneID: 10450
NCBI-ProteinID: NP_006103
OMIM: 602435
HGNC: 9258
Ensembl: ENSG00000084072
UniProt: Q9UNP9
Structure
Position
1:39738882..39763914
AA seq 301 aa
MATTKRVLYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVEFELAEDA
AAAIDNMNESELFGRTIRVNLAKPMRIKEGSSRPVWSDDDWLKKFSGKTLEENKEEEGSE
PPKAETQEGEPIAKKARSNPQVYMDIKIGNKPAGRIQMLLRSDVVPMTAENFRCLCTHEK
GFGFKGSSFHRIIPQFMCQGGDFTNHNGTGGKSIYGKKFDDENFILKHTGPGLLSMANSG
PNTNGSQFFLTCDKTDWLDGKHVVFGEVTEGLDVLRQIEAQGSKDGKPKQKVIIADCGEY
V
NT seq 906 nt   +upstreamnt  +downstreamnt
atggccaccaccaagcgcgtcttgtacgtgggtggactggcagaggaagtggacgacaaa
gttcttcatgctgcgttcattccttttggagacatcacagatattcagattcctctggat
tatgaaacagaaaagcaccgaggatttgcttttgttgaatttgagttggcagaggatgct
gcagcagctatcgacaacatgaatgaatctgagctttttggacgtacaattcgtgtcaat
ttggccaaaccaatgagaattaaggaaggctcttccaggccagtttggtcagatgatgac
tggttgaagaagttttctgggaagacgcttgaagagaataaagaggaagaagggtcagag
cctcccaaagcagagacccaggagggagagcccattgctaaaaaggcccgctcaaatcct
caggtgtacatggacatcaagattgggaacaagccggctggccgcatccagatgctcctg
cgttctgatgtcgtgcccatgacagcagagaatttccgctgcctgtgcactcatgaaaag
ggctttggctttaagggaagcagcttccaccgcatcatcccccagttcatgtgccagggc
ggtgatttcacaaaccacaatggcactgggggcaagtccatctatgggaagaagttcgat
gatgaaaactttatcctcaagcatacgggaccaggtctactatccatggccaactctggc
ccaaacaccaatggctctcagttcttcctgacatgtgacaagacagactggctggatggc
aagcatgtggtgtttggagaggtcaccgaaggcctagatgtcttgcggcaaattgaggcc
cagggcagcaaggacgggaagccaaagcagaaggtgatcatcgccgactgtggggagtac
gtgtga

  All links  
Disease (1)   
   OMIM (1)   
Gene (17)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (5)   
   OC (1)   
Protein sequence (19)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (17)   
DNA sequence (66)   
   RefSeq(nuc) (20)   
   GenBank (23)   
   EMBL (23)   
3D Structure (36)   
   PDB (36)   
Protein domain (6)   
   Pfam (6)   
All databases (145)   

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