KEGG   Homo sapiens (human): 10526
Entry
10526             CDS       T01001                                 
Symbol
IPO8, RANBP8, VISS
Name
(RefSeq) importin-8 isoform 1
  KO
K18755  importin-8
Organism
hsa  Homo sapiens (human)
Pathway
hsa03013  Nucleocytoplasmic transport
Disease
H02703  VISS syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   03013 Nucleocytoplasmic transport
    10526 (IPO8)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    10526 (IPO8)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    Common to processing body (P body) and stress granule
     10526 (IPO8)
SSDB
Motif
Pfam: IBN_N TPR_IPO11 Cse1 HEAT_IPO9_c CandA_N Xpo1
Other DBs
NCBI-GeneID: 10526
NCBI-ProteinID: NP_006381
OMIM: 605600
HGNC: 9853
Ensembl: ENSP00000256079.4
UniProt: O15397
Position
12:complement(30628988..30695869)
AA seq 1037 aa
MDLNRIIQALKGTIDPKLRIAAENELNQSYKIINFAPSLLRIIVSDHVEFPVRQAAAIYL
KNMVTQYWPDREPPPGEAIFPFNIHENDRQQIRDNIVEGIIRSPDLVRVQLTMCLRAIIK
HDFPGHWPGVVDKIDYYLQSQSSASWLGSLLCLYQLVKTYEYKKAEEREPLIIAMQIFLP
RIQQQIVQLLPDSSYYSVLLQKQILKIFYALVQYALPLQLVNNQTMTTWMEIFRTIIDRT
VPPETLHIDEDDRPELVWWKCKKWALHIVARLFERYGSPGNVTKEYFEFSEFFLKTYAVG
IQQVLLKILDQYRQKEYVAPRVLQQAFNYLNQGVVHSITWKQMKPHIQNISEDVIFSVMC
YKDEDEELWQEDPYEYIRMKFDIFEDYASPTTAAQTLLYTAAKKRKEVLPKMMAFCYQIL
TDPNFDPRKKDGALHVIGSLAEILLKKSLFKDQMELFLQNHVFPLLLSNLGYLRARSCWV
LHAFSSLKFHNELNLRNAVELAKKSLIEDKEMPVKVEAALALQSLISNQIQAKEYMKPHV
RPIMQELLHIVRETENDDVTNVIQKMICEYSQEVASIAVDMTQHLAEIFGKVLQSDEYEE
VEDKTVMAMGILHTIDTILTVVEDHKEITQQLENICLRIIDLVLQKHVIEFYEEILSLAY
SLTCHSISPQMWQLLGILYEVFQQDCFEYFTDMMPLLHNYVTIDTDTLLSNAKHLEILFT
MCRKVLCGDAGEDAECHAAKLLEVIILQCKGRGIDQCIPLFVQLVLERLTRGVKTSELRT
MCLQVAIAALYYNPDLLLHTLERIQLPHNPGPITVQFINQWMNDTDCFLGHHDRKMCIIG
LSILLELQNRPPAVDAVVGQIVPSILFLFLGLKQVCATRQLVNREDRSKAEKADMEENEE
ISSDEEETNVTAQAMQSNNGRGEDEEEEDDDWDEEVLEETALEGFSTPLDLDNSVDEYQF
FTQALITVQSRDAAWYQLLMAPLSEDQRTALQEVYTLAEHRRTVAEAKKKIEQQGGFTFE
NKGVLSAFNFGTVPSNN
NT seq 3114 nt   +upstreamnt  +downstreamnt
atggacctcaaccggatcatccaggcgctgaagggcaccatcgacccgaagttgcggatt
gcagccgagaacgagctcaaccagtcctacaagattatcaattttgcccccagtttactt
cggattatagtctctgaccatgtggaattcccagtacgacaggcagctgccatttacctg
aagaacatggtgacacaatactggccagatcgagaacctccaccaggagaagcaatattt
ccattcaacattcacgaaaacgatcgccagcaaatacgtgataacattgtggaaggaata
attcggtctccagatttagtgagagtccaattaacaatgtgtctccgtgccatcataaaa
catgattttcctggtcactggccaggagtggtcgacaagatagactattacttgcaatca
cagagcagtgcaagctggcttggcagtttattatgcctgtatcaactggtgaagacatat
gaatataagaaagcagaagagagagaacctcttataatagcaatgcagatattcctgcct
cgtattcagcaacaaattgttcagctccttcctgattcctcctattattctgtattactg
cagaaacaaattctgaaaatcttttatgcacttgttcagtatgcattgcctcttcagcta
gtgaataaccaaaccatgacaacatggatggagatcttccgaactattatcgacaggacc
gttcctcctgagactctgcacattgatgaggatgatagaccagaactggtatggtggaag
tgtaagaagtgggcactgcatattgtagctcggctctttgaacgatatggaagcccagga
aatgtcacaaaagaatactttgaattttctgaattctttttgaaaacctatgcagtgggc
attcagcaggtgctactaaaaattttagatcaatatagacagaaagaatatgtagctccc
cgtgttcttcagcaagcattcaactatctcaaccaaggggtggttcattctataacctgg
aagcagatgaagccacacatacagaatatctctgaagatgtgattttttctgtgatgtgt
tataaagatgaggatgaagagctgtggcaagaagatccatatgagtatataaggatgaaa
tttgatatttttgaagattatgcttctcccaccacagcagcccagactctcttatatact
gctgcaaagaaaagaaaagaggtgttgccaaaaatgatggcattctgttatcaaatcctg
acagacccgaactttgaccctaggaagaaagatggagccctgcatgtgattggttcccta
gctgagattttactgaagaagagtttattcaaggaccaaatggagctgtttctacaaaat
catgtatttccattattattgtctaacctgggatatcttcgagctagatcttgctgggta
cttcatgcatttagttctttgaagttccataatgagctcaatctaagaaatgccgttgaa
ttagcgaagaagagcctgattgaagataaagagatgcctgtcaaagttgaagctgccctt
gctcttcagtctttaatttctaaccagatacaagctaaggaatatatgaagccacatgtg
aggcctattatgcaggaactgttgcacattgttagagagacagaaaatgatgatgttact
aatgtcatccagaagatgatatgtgaatacagtcaagaggtagcctcaattgctgttgat
atgacccaacacttggctgagatatttggcaaagttcttcaaagtgatgaatatgaagaa
gttgaagacaaaacagtaatggctatgggaattttacataccattgatactatcttaaca
gttgtagaagatcataaagagattacccagcagttagagaatatctgtctacggatcatt
gatcttgttctgcagaaacatgtaattgaattctatgaagaaattctttccctggcatac
agtttaacctgccacagtatttcccctcaaatgtggcagcttctaggtatactatatgaa
gtgtttcagcaggattgctttgaatactttacagacatgatgcctctcctgcataattat
gtgacaatagatacagataccttactatcaaatgcaaaacatttagaaattctttttaca
atgtgtaggaaggtactatgtggagatgcaggagaagatgcagagtgtcatgcagctaaa
cttctggaagtcatcattcttcagtgcaaaggaaggggaattgatcagtgcattccactc
ttcgttcaacttgttttggagagattaactcgaggggtcaaaactagtgagcttcgtact
atgtgtcttcaggttgcaattgctgccttgtactacaaccctgatttgctgctacatact
ttagaacgaattcagttgcctcacaaccctggacctatcactgtacagtttataaatcaa
tggatgaatgatacagattgttttcttgggcatcatgaccggaagatgtgtataatagga
ctgagtatccttttggaattgcaaaatcgacctcctgcagtagatgctgtggtgggacag
attgttccctcaattcttttccttttccttggcctaaagcaggtctgtgctactagacaa
ctggtaaaccgggaagatcgttcaaaagcagagaaagctgatatggaagaaaatgaggag
atttcaagtgatgaagaggagacaaatgtaactgctcaagcaatgcagtcaaataatgga
agaggtgaagatgaggaggaggaagatgatgactgggatgaagaagtattggaagaaacc
gcgcttgaggggttcagtactccacttgaccttgacaatagtgtggatgaatatcagttt
tttacacaagctctgataactgtgcagagtcgagatgcagcctggtaccagctgctgatg
gcaccactcagcgaggatcagaggacagcactgcaggaggtgtacacactggcagagcac
cgacggacggtggcagaggcaaagaagaagattgaacaacagggaggcttcacctttgaa
aacaaaggagtcctctccgcatttaattttgggactgtgcccagcaacaactga

  All links  
Disease (2)   
   OMIM (2)   
Gene (15)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (11)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (9)   
DNA sequence (43)   
   RefSeq(nuc) (9)   
   GenBank (17)   
   EMBL (17)   
Protein domain (6)   
   Pfam (6)   
All databases (77)   

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