KEGG   Homo sapiens (human): 10580
Entry
10580             CDS       T01001                                 

Gene name
SORBS1, CAP, FLAF2, R85FL, SH3D5, SH3P12, SORB1
Definition
(RefSeq) sorbin and SH3 domain containing 1
  KO
K06086  sorbin and SH3 domain containing protein 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa03320  PPAR signaling pathway
hsa04520  Adherens junction
hsa04910  Insulin signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    10580 (SORBS1)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    10580 (SORBS1)
   03320 PPAR signaling pathway
    10580 (SORBS1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04990 Domain-containing proteins not elsewhere classified [BR:hsa04990]
    10580 (SORBS1)
Domain-containing proteins not elsewhere classified [BR:hsa04990]
 Src homology (SH) domain-containing proteins
  Other SH2 and SH3-containing proteins
   10580 (SORBS1)
SSDB
Motif
Pfam: SH3_9 SH3_1 SH3_2 Sorb
Other DBs
NCBI-GeneID: 10580
NCBI-ProteinID: NP_001030126
OMIM: 605264
HGNC: 14565
Ensembl: ENSG00000095637
Vega: OTTHUMG00000018812
Pharos: Q9BX66(Tbio)
UniProt: Q9BX66
Structure
PDB: 

Position
10q24.1
AA seq 1292 aa
MSSECDGGSKAVMNGLAPGSNGQDKATADPLRARSISAVKIIPVKTVKNASGLVLPTDMD
LTKICTGKGAVTLRASSSYRETPSSSPASPQETRQHESKPGLEPEPSSADEWRLSSSADA
NGNAQPSSLAAKGYRSVHPNLPSDKSQDATSSSAAQPEVIVVPLYLVNTDRGQEGTARPP
TPLGPLGCVPTIPATASAASPLTFPTLDDFIPPHLQRWPHHSQPARASGSFAPISQTPPS
FSPPPPLVPPAPEDLRRVSEPDLTGAVSSTDSSPLLNEVSSSLIGTDSQAFPSVSKPSSA
YPSTTIVNPTIVLLQHNREQQKRLSSLSDPVSERRVGEQDSAPTQEKPTSPGKAIEKRAK
DDSRRVVKSTQDLSDVSMDEVGIPLRNTERSKDWYKTMFKQIHKLNRDTPEENPYFPTYK
FPELPEIQQTSEEDNPYTPTYQFPASTPSPKSEDDDSDLYSPRYSFSEDTKSPLSVPRSK
SEMSYIDGEKVVKRSATLPLPARSSSLKSSSERNDWEPPDKKVDTRKYRAEPKSIYEYQP
GKSSVLTNEKMSRDISPEEIDLKNEPWYKFFSELEFGKPPPKKIWDYTPGDCSILPREDR
KTNLDKDLSLCQTELEADLEKMETLNKAPSANVPQSSAISPTPEISSETPGYIYSSNFHA
VKRESDGAPGDLTSLENERQIYKSVLEGGDIPLQGLSGLKRPSSSASTKDSESPRHFIPA
DYLESTEEFIRRRHDDKEKLLADQRRLKREQEEADIAARRHTGVIPTHHQFITNERFGDL
LNIDDTAKRKSGSEMRPARAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEGEHHGRVG
IFPRTYIELLPPAEKAQPKKLTPVQVLEYGEAIAKFNFNGDTQVEMSFRKGERITLLRQV
DENWYEGRIPGTSRQGIFPITYVDVIKRPLVKNPVDYMDLPFSSSPSRSATASPQFSSHS
KLITPAPSSLPHSRRALSPEMHAVTSEWISLTVGVPGRRSLALTPPLPPLPEASIYNTDH
LALSPRASPSLSLSLPHLSWSDRPTPRSVASPLALPSPHKTYSLAPTSQASLHMNGDGGV
HTPSSGIHQDSFLQLPLGSSDSVISQLSDAFSSQSKRQPWREESGQYERKAERGAGERGP
GGPKISKKSCLKPSDVVRCLSTEQRLSDLNTPEESRPGKPLGSAFPGSEAEQTERHRGGE
QAGRKAARRGGSQQPQAQQRRVTPDRSQTSQDLFSYQALYSYIPQNDDELELRDGDIVDV
MEKCDDGWFVGTSRRTKQFGTFPGNYVKPLYL
NT seq 3879 nt   +upstreamnt  +downstreamnt
atgagttctgaatgtgatggtggttccaaagctgtgatgaatggcttggcacctggcagc
aatgggcaagacaaagcaactgccgaccctttacgcgcacgctctatttctgctgttaaa
atcattcctgtgaagacagtgaaaaacgcctcaggcctagttctccctacagacatggat
cttacaaaaatctgcactgggaagggagcggtgactctccgggcctcgtcttcctacagg
gaaaccccaagcagtagccctgcgagccctcaggaaacccggcaacacgaaagcaaacca
ggtctggagccagagccttcttcagcagatgagtggaggctttcttccagtgctgatgcc
aatggaaatgcccagccctcttcactcgctgccaagggctacagaagtgtgcatcccaac
cttccttctgacaagtcccaggatgccacttcctccagtgcagcccagccggaggtaata
gttgtccctctctacctggttaatactgacagagggcaagaaggcactgccagacctcca
acacctctggggcctcttggctgcgtccccacaatcccagcgactgcctctgccgcctca
cctctgaccttcccgactctagatgatttcattccccctcatctgcagaggtggccccac
cacagccagccagcccgcgcctctggctcctttgcccccattagccagacgccaccatcc
ttctcaccaccacctccgctggtccctcctgccccggaggacctccgcagagtctcggag
cctgacctcacgggagctgtttcgagtaccgattccagtcctctactaaatgaagtttct
tcttcccttattggaactgattcccaagcctttccatcagttagcaagccttcatccgcc
tatccctccacaacgattgtcaatcctactattgtgctcttgcaacacaatcgagaacag
caaaaacgactcagtagcctttcagatcctgtctcagaaagaagagtgggagagcaggac
tcagcaccaacccaggaaaaacccacctcacctggcaaggctattgaaaaaagagcaaag
gatgacagtaggcgggtggtgaagagcactcaggacttaagcgatgtttccatggatgaa
gtgggcatcccactccggaacactgagagatcaaaagactggtacaagactatgtttaaa
cagatccacaaactgaacagagacactcctgaagaaaacccttatttccctacgtacaaa
ttccctgaacttcctgaaatccagcaaacttccgaagaggacaatccttacactcccacc
taccagtttcctgcatctactcctagtcctaaatctgaagatgatgattcagatctgtac
tctcccagatactcattttctgaagacacaaaatctcccctttctgtgcctcgctcaaaa
agtgagatgagctacattgatggtgagaaggtagtcaagaggtcggccacactacccctc
ccagcccgctcttcctcactgaagtcaagctcagaaagaaatgactgggaacccccagat
aagaaagtagacacaagaaaatatcgtgcagagcccaagagcatttacgaatatcagcct
ggcaagtcttccgttctgaccaacgaaaagatgagtcgggatataagcccagaagagata
gatttaaagaatgaaccttggtataaattcttttcggaattggagtttgggaaaccgcct
cccaaaaagatatgggattatactcctggagactgctctatccttcctagagaggataga
aagactaatctagacaaagatctcagcctctgccagacagagttagaggcagatttagaa
aaaatggagacgcttaataaagcacccagtgcaaacgtgccacagagctcagccatcagc
cctactccggaaatttcttcagagactcctggatatatatattcttccaacttccatgca
gtgaagagggaatcagacggggctcctggggatctcactagcttggagaatgagagacaa
atttataaaagtgtcttggaaggtggtgacatccctcttcagggcctgagtgggctcaag
cgaccatccagctctgcttccactaaagattcagaatcgccaagacattttataccagct
gattacttggaatccacggaagaatttattcgaagacgtcatgatgataaagagaaactt
ttagcggaccagagacgacttaaacgcgagcaagaagaggctgatattgcagctcgacgc
cacacaggcgtcattccgacgcaccatcagtttatcactaatgagcgctttggggacctc
ctcaatatagacgatactgcaaaaaggaaatctgggtcagagatgagacctgccagagcc
aaatttgactttaaagctcagacactaaaggagcttcctctgcagaagggagatattgtt
tacatttataagcaaattgatcagaactggtatgaaggagaacaccacggccgggtggga
atcttcccacgcacctacatcgagcttcttcctcctgctgagaaggcacagcccaaaaag
ttgacaccagtgcaggttttggaatatggagaagctattgctaagtttaactttaatggt
gatacacaagtagaaatgtccttcagaaagggtgagaggatcacactgctccggcaggta
gatgagaactggtacgaagggaggatcccggggacatcccgacaaggcatcttccccatc
acctacgtggatgtgatcaagcgaccactggtgaaaaaccctgtggattacatggacctg
cctttctcctcctccccaagtcgcagtgccactgcaagcccacagttttccagtcacagc
aagctcatcacgccagccccctcatctctgccccactcccgccgagccctgtcccccgag
atgcacgctgtcacctctgagtggatctcactgactgtgggggtcccaggcaggcgttct
ctggccctgaccccacccttgcctcctctgccagaggcttctatctataacactgaccac
ctcgccttgtcaccaagggccagtccctccctgtctctcagcctcccccatttgagttgg
tcagatcgtcccaccccacgatcagtagcttctccactggccctaccttccccacacaaa
acctactccctagcacctacttcccaggcctcccttcacatgaatggagacggtggtgtc
cacacgccatcttcaggcatccaccaagatagcttcttgcagctgccgctggggagctct
gatagtgtcatctcccagcttagtgatgcctttagcagccagagcaagaggcagccatgg
cgcgaagagagtggacaatatgagaggaaagcagagaggggggcaggcgaaagaggccct
ggtggacccaagatctctaagaagagctgcttgaagccttcagacgtggtcaggtgcctg
agtactgaacagagactctcagatctcaacacccctgaggagagccggcccggcaagccc
ctgggtagcgcttttccaggaagtgaggctgagcagacagagcggcatagaggtggcgag
caggcggggaggaaagctgctcggagaggtgggagccagcaacctcaagcccagcagcga
agagtcacccccgacaggagtcaaacctcacaagatttatttagctatcaagcattatat
agctatataccacagaatgatgatgagttggaactccgcgatggagatatcgttgatgtc
atggaaaaatgtgacgatggatggtttgttggtacttcaagaaggacaaagcagtttggt
acttttccaggcaactatgtaaaacctttgtatctataa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (35)   
   KEGG ORTHOLOGY (1)   
   RefGene (25)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (79)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (77)   
DNA sequence (125)   
   RefSeq(nuc) (77)   
   GenBank (24)   
   EMBL (24)   
Protein domain (4)   
   Pfam (4)   
All databases (250)   

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