KEGG   Homo sapiens (human): 10592
Entry
10592             CDS       T01001                                 
Symbol
SMC2, CAP-E, CAPE, SMC-2, SMC2L1
Name
(RefSeq) structural maintenance of chromosomes protein 2
  KO
K06674  structural maintenance of chromosome 2
Organism
hsa  Homo sapiens (human)
Network
nt06512  Chromosome cohesion and segregation
  Element
N01497  Condensin loading
N01498  Inhibition of condensin II association
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    10592 (SMC2)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Chromosome condensation proteins
   Condensin I
    10592 (SMC2)
   Condensin II
    10592 (SMC2)
SSDB
Motif
Pfam: SMC_N SMC_hinge AAA_23 AAA_21 AAA_15 AAA_29 DUF4200 ABC_tran GrpE
Other DBs
NCBI-GeneID: 10592
NCBI-ProteinID: NP_001036015
OMIM: 605576
HGNC: 14011
UniProt: O95347 Q05BV1 B3KMB1 Q6IPS5
Structure
Position
9:104088263..104141419
AA seq 1197 aa
MHIKSIILEGFKSYAQRTEVNGFDPLFNAITGLNGSGKSNILDSICFLLGISNLSQVRAS
NLQDLVYKNGQAGITKASVSITFDNSDKKQSPLGFEVHDEITVTRQVVIGGRNKYLINGV
NANNTRVQDLFCSVGLNVNNPHFLIMQGRITKVLNMKPPEILSMIEEAAGTRMYEYKKIA
AQKTIEKKEAKLKEIKTILEEEITPTIQKLKEERSSYLEYQKVMREIEHLSRLYIAYQFL
LAEDTKVRSAEELKEMQDKVIKLQEELSENDKKIKALNHEIEELEKRKDKETGGILRSLE
DALAEAQRVNTKSQSAFDLKKKNLACEESKRKELEKNMVEDSKTLAAKEKEVKKITDGLH
ALQEASNKDAEALAAAQQHFNAVSAGLSSNEDGAEATLAGQMMACKNDISKAQTEAKQAQ
MKLKHAQQELKNKQAEVKKMDSGYRKDQEALEAVKRLKEKLEAEMKKLNYEENKEESLLE
KRRQLSRDIGRLKETYEALLARFPNLRFAYKDPEKNWNRNCVKGLVASLISVKDTSATTA
LELVAGERLYNVVVDTEVTGKKLLERGELKRRYTIIPLNKISARCIAPETLRVAQNLVGP
DNVHVALSLVEYKPELQKAMEFVFGTTFVCDNMDNAKKVAFDKRIMTRTVTLGGDVFDPH
GTLSGGARSQAASILTKFQELKDVQDELRIKENELRALEEELAGLKNTAEKYRQLKQQWE
MKTEEADLLQTKLQQSSYHKQQEELDALKKTIEESEETLKNTKEIQRKAEEKYEVLENKM
KNAEAERERELKDAQKKLDCAKTKADASSKKMKEKQQEVEAITLELEELKREHTSYKQQL
EAVNEAIKSYESQIEVMAAEVAKNKESVNKAQEEVTKQKEVITAQDTVIKAKYAEVAKHK
EQNNDSQLKIKELDHNISKHKREAEDGAAKVSKMLKDYDWINAERHLFGQPNSAYDFKTN
NPKEAGQRLQKLQEMKEKLGRNVNMRAMNVLTEAEERYNDLMKKKRIVENDKSKILTTIE
DLDQKKNQALNIAWQKVNKDFGSIFSTLLPGANAMLAPPEGQTVLDGLEFKVALGNTWKE
NLTELSGGQRSLVALSLILSMLLFKPAPIYILDEVDAALDLSHTQNIGQMLRTHFTHSQF
IVVSLKEGMFNNANVLFKTKFVDGVSTVARFTQCQNGKISKEAKSKAKPPKGAHVEV
NT seq 3594 nt   +upstreamnt  +downstreamnt
atgcatattaagtcaattattctagagggattcaagtcctatgctcagaggaccgaagtc
aatggttttgaccccctcttcaatgctatcactggcttaaatggtagtgggaaatccaac
atattggactccatctgctttttgctgggcatctccaacctgtctcaggttcgggcttct
aatttacaagatttagtttacaaaaatgggcaggctggtattaccaaagcctctgtgtca
atcacttttgataattctgacaaaaagcaaagtcctttaggatttgaggttcatgatgaa
atcacagtaacaaggcaggtggttattggtggtagaaataaatatttaatcaatggagtc
aatgccaacaacaccagagtacaggatctcttctgttctgttggccttaatgttaacaac
cctcactttctcatcatgcagggccgaattacaaaagtattgaatatgaaacctccagag
attttatccatgatagaagaagcagctggaaccaggatgtatgaatacaaaaaaatagct
gcacagaaaactatagaaaaaaaggaggctaagctgaaagaaattaagacgatacttgaa
gaagagattactccaaccattcaaaaattaaaagaggaaagatcgtcctacttggagtac
caaaaagtaatgagagaaatagaacatttgagtcgtttatatattgcttatcagtttttg
ctggctgaagataccaaagtacgctcagctgaggaattaaaagaaatgcaagataaagtt
ataaagcttcaggaagaattgtctgagaatgataaaaaaataaaagcacttaatcatgaa
atagaagaattggaaaaaagaaaagataaggaaactggaggtatacttcgatctttagaa
gatgctcttgcagaggctcagcgagttaatactaaatctcaaagcgcatttgatctcaag
aagaaaaatctggcatgtgaggaaagcaaacgcaaagagctggaaaaaaatatggttgag
gactcaaaaactttagcagcaaaggaaaaagaggttaaaaagataacagatggactgcat
gcccttcaagaagcaagtaataaagatgctgaagctctggcagctgcacagcagcacttc
aatgctgtttccgctggcctgtccagtaatgaagatggagcagaagcaactcttgctggt
caaatgatggcctgtaaaaatgatataagtaaagctcagacagaagccaaacaggctcag
atgaagttgaagcatgctcaacaggaattaaagaataaacaagctgaagttaagaagatg
gatagtggctacaggaaggatcaagaagctctagaagctgtaaaaagacttaaagaaaaa
cttgaagctgaaatgaaaaagctaaattatgaagaaaataaagaggaaagccttttggaa
aagcgcaggcagctgtctcgtgatattggtagattgaaagaaacatatgaagctctatta
gccagatttcccaatcttcgatttgcatacaaggatccagagaagaactggaatagaaat
tgtgtgaaaggacttgtggcttctctgattagtgtgaaagacacttctgcaaccacagct
ttagaattagtggctggagaacgactctacaatgttgtagtagacacagaagttactggt
aaaaagctactagaaaggggggaactgaaacgtcgatacactataattccactcaataaa
atttcagccagatgtattgcaccagaaactctgagagttgctcagaatcttgttggccct
gacaacgttcatgtggctctttccttggttgaatataaaccagaacttcagaaagcaatg
gagtttgtctttggaacaacatttgtttgtgacaatatggataatgccaaaaaagtggcc
tttgataagaggataatgactagaactgtaactctcggaggtgatgtgtttgatcctcat
gggacattgagtggaggtgctcgatcccaggcagcttccattttaaccaagtttcaagaa
ctcaaagatgttcaggatgaactgagaatcaaagagaatgagctgcgggctctagaagag
gaattagcaggtcttaaaaacactgctgaaaagtatcgccaactaaaacagcagtgggag
atgaaaactgaagaggcagatttattacaaaccaagctccagcaaagctcatatcacaag
caacaagaagaattagatgcccttaaaaaaaccattgaggaaagtgaggagactttgaaa
aacactaaagaaatccaaagaaaagcagaagaaaaatatgaagtattggaaaataaaatg
aaaaatgcagaagctgaaagagagcgagaactgaaagatgctcagaaaaaactggattgt
gccaaaacaaaggcagatgcatctagcaagaagatgaaagaaaaacaacaggaagttgaa
gctatcactctggaactggaagagctcaagagagagcatacatcttacaaacaacagctt
gaagctgtaaatgaagctatcaaatcctatgaaagtcagattgaagtaatggcagctgag
gtggctaaaaataaggagtcagtaaataaagctcaagaagaggtgaccaagcaaaaagag
gtgataacagcccaagacactgtaattaaagctaaatatgcagaagtggcaaaacacaag
gagcaaaacaatgattctcagcttaaaattaaggaattagaccacaacatcagcaaacat
aaacgggaggctgaagatggtgctgcaaaggtatccaaaatgttgaaagattatgactgg
attaatgcagagagacacctctttggccaacccaatagtgcctatgatttcaaaactaac
aaccctaaagaagctggtcagagacttcagaagttgcaagaaatgaaggagaaactagga
agaaatgtcaatatgagagctatgaatgtattgacagaagctgaagagcgatacaatgac
ttgatgaagaagaagagaattgtagaaaatgacaaatccaaaattcttacaactatagaa
gaccttgaccagaagaaaaaccaagccctaaatattgcatggcaaaaggtgaacaaggac
tttgggtctattttttctactcttttgcctggtgctaatgctatgcttgcaccaccagag
ggtcaaactgttttggatggtctggagttcaaggttgccttgggaaatacctggaaagaa
aacctaactgaacttagtggtggtcagaggtctttagtggccttgtcattaatactgtcc
atgcttctcttcaaacctgctccaatttatatccttgatgaggtagatgcagccttggat
ctttctcatacccaaaacattggacagatgctgcgtactcatttcacacattctcagttc
attgtggtgtcactaaaagaaggtatgttcaacaatgcaaacgttcttttcaaaaccaag
tttgtggatggtgtttctacagtagccagatttactcaatgtcaaaatggaaagatttca
aaggaagcaaaatccaaggcaaaaccacccaaaggagcacatgtggaagtttaa

  All links  
Disease (1)   
   OMIM (1)   
Gene (24)   
   RefGene (16)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
Protein sequence (46)   
   UniProt (4)   
   SWISS-PROT (1)   
   RefSeq(pep) (41)   
DNA sequence (87)   
   RefSeq(nuc) (41)   
   GenBank (23)   
   EMBL (23)   
3D Structure (2)   
   PDB (2)   
Protein domain (9)   
   Pfam (9)   
All databases (169)   

Download RDF
DBGET integrated database retrieval system