KEGG   Homo sapiens (human): 1071
Entry
1071              CDS       T01001                                 

Gene name
CETP, BPIFF, HDLCQ10
Definition
(RefSeq) cholesteryl ester transfer protein
  KO
K16835  cholesteryl ester transfer protein
Organism
hsa  Homo sapiens (human)
Pathway
hsa04979  Cholesterol metabolism
Disease
H01199  Hyperalphalipoproteinemia
Drug target
Anacetrapib: D08855
Dalcetrapib: D09708
Evacetrapib: D10121
Omega-3-acid ethyl esters: D05255<JP/US>
Torcetrapib: D06195
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09154 Digestive system
   04979 Cholesterol metabolism
    1071 (CETP)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hsa02000]
    1071 (CETP)
   04147 Exosome [BR:hsa04147]
    1071 (CETP)
Transporters [BR:hsa02000]
 Other transporters
  Pores ion channels [TC:1]
   1071 (CETP)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   1071 (CETP)
SSDB
Motif
Pfam: LBP_BPI_CETP LBP_BPI_CETP_C
Other DBs
NCBI-GeneID: 1071
NCBI-ProteinID: NP_000069
OMIM: 118470
HGNC: 1869
Ensembl: ENSG00000087237
Vega: OTTHUMG00000133279
Pharos: P11597(Tchem)
UniProt: P11597 A0A0S2Z3F6
Structure
PDB: 
2OBD 4EWS 4F2A

Position
16q13
AA seq 493 aa
MLAATVLTLALLGNAHACSKGTSHEAGIVCRITKPALLVLNHETAKVIQTAFQRASYPDI
TGEKAMMLLGQVKYGLHNIQISHLSIASSQVELVEAKSIDVSIQNVSVVFKGTLKYGYTT
AWWLGIDQSIDFEIDSAIDLQINTQLTCDSGRVRTDAPDCYLSFHKLLLHLQGEREPGWI
KQLFTNFISFTLKLVLKGQICKEINVISNIMADFVQTRAASILSDGDIGVDISLTGDPVI
TASYLESHHKGHFIYKNVSEDLPLPTFSPTLLGDSRMLYFWFSERVFHSLAKVAFQDGRL
MLSLMGDEFKAVLETWGFNTNQEIFQEVVGGFPSQAQVTVHCLKMPKISCQNKGVVVNSS
VMVKFLFPRPDQQHSVAYTFEEDIVTTVQASYSKKKLFLSLLDFQITPKTVSNLTESSSE
SVQSFLQSMITAVGIPEVMSRLEVVFTALMNSKGVSLFDIINPEIITRDGFLLLQMDFGF
PEHLLVDFLQSLS
NT seq 1482 nt   +upstreamnt  +downstreamnt
atgctggctgccacagtcctgaccctggccctgctgggcaatgcccatgcctgctccaaa
ggcacctcgcacgaggcaggcatcgtgtgccgcatcaccaagcctgccctcctggtgttg
aaccacgagactgccaaggtgatccagaccgccttccagcgagccagctacccagatatc
acgggcgagaaggccatgatgctccttggccaagtcaagtatgggttgcacaacatccag
atcagccacttgtccatcgccagcagccaggtggagctggtggaagccaagtccattgat
gtctccattcagaacgtgtctgtggtcttcaaggggaccctgaagtatggctacaccact
gcctggtggctgggtattgatcagtccattgacttcgagatcgactctgccattgacctc
cagatcaacacacagctgacctgtgactctggtagagtgcggaccgatgcccctgactgc
tacctgtctttccataagctgctcctgcatctccaaggggagcgagagcctgggtggatc
aagcagctgttcacaaatttcatctccttcaccctgaagctggtcctgaagggacagatc
tgcaaagagatcaacgtcatctctaacatcatggccgattttgtccagacaagggctgcc
agcatcctttcagatggagacattggggtggacatttccctgacaggtgatcccgtcatc
acagcctcctacctggagtcccatcacaagggtcatttcatctacaagaatgtctcagag
gacctccccctccccaccttctcgcccacactgctgggggactcccgcatgctgtacttc
tggttctctgagcgagtcttccactcgctggccaaggtagctttccaggatggccgcctc
atgctcagcctgatgggagacgagttcaaggcagtgctggagacctggggcttcaacacc
aaccaggaaatcttccaagaggttgtcggcggcttccccagccaggcccaagtcaccgtc
cactgcctcaagatgcccaagatctcctgccaaaacaagggagtcgtggtcaattcttca
gtgatggtgaaattcctctttccacgcccagaccagcaacattctgtagcttacacattt
gaagaggatatcgtgactaccgtccaggcctcctattctaagaaaaagctcttcttaagc
ctcttggatttccagattacaccaaagactgtttccaacttgactgagagcagctccgag
tccgtccagagcttcctgcagtcaatgatcaccgctgtgggcatccctgaggtcatgtct
cggctcgaggtagtgtttacagccctcatgaacagcaaaggcgtgagcctcttcgacatc
atcaaccctgagattatcactcgagatggcttcctgctgctgcagatggactttggcttc
cctgagcacctgctggtggatttcctccagagcttgagctag

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Drug (5)   
   KEGG DRUG (5)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (6)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (21)   
   RefSeq(nuc) (3)   
   GenBank (9)   
   EMBL (9)   
Protein domain (2)   
   Pfam (2)   
All databases (53)   

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