KEGG   Homo sapiens (human): 10723
Entry
10723             CDS       T01001                                 
Symbol
SLC12A7, KCC4
Name
(RefSeq) solute carrier family 12 member 7
  KO
K13627  solute carrier family 12 (potassium/chloride transporter), member 7
Organism
hsa  Homo sapiens (human)
Pathway
hsa04966  Collecting duct acid secretion
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09155 Excretory system
   04966 Collecting duct acid secretion
    10723 (SLC12A7)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hsa02000]
    10723 (SLC12A7)
Transporters [BR:hsa02000]
 Solute carrier family (SLC)
  SLC12: Electroneutral cation-coupled Cl cotransporter
   10723 (SLC12A7)
SSDB
Motif
Pfam: AA_permease SLC12 AA_permease_2 DUF4430
Other DBs
NCBI-GeneID: 10723
NCBI-ProteinID: NP_006589
OMIM: 604879
HGNC: 10915
Ensembl: ENSP00000264930.5
UniProt: Q9Y666
Structure
Position
5:complement(1050384..1155899)
AA seq 1083 aa
MPTNFTVVPVEAHADGGGDETAERTEAPGTPEGPEPERPSPGDGNPRENSPFLNNVEVEQ
ESFFEGKNMALFEEEMDSNPMVSSLLNKLANYTNLSQGVVEHEEDEESRRREAKAPRMGT
FIGVYLPCLQNILGVILFLRLTWIVGVAGVLESFLIVAMCCTCTMLTAISMSAIATNGVV
PAGGSYYMISRSLGPEFGGAVGLCFYLGTTFAGAMYILGTIEIFLTYISPGAAIFQAEAA
GGEAAAMLHNMRVYGTCTLVLMALVVFVGVKYVNKLALVFLACVVLSILAIYAGVIKSAF
DPPDIPVCLLGNRTLSRRSFDACVKAYGIHNNSATSALWGLFCNGSQPSAACDEYFIQNN
VTEIQGIPGAASGVFLENLWSTYAHAGAFVEKKGVPSVPVAEESRASALPYVLTDIAASF
TLLVGIYFPSVTGIMAGSNRSGDLKDAQKSIPTGTILAIVTTSFIYLSCIVLFGACIEGV
VLRDKFGEALQGNLVIGMLAWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIARDGIVP
FLQVFGHGKANGEPTWALLLTVLICETGILIASLDSVAPILSMFFLMCYLFVNLACAVQT
LLRTPNWRPRFKFYHWTLSFLGMSLCLALMFICSWYYALSAMLIAGCIYKYIEYRGAEKE
WGDGIRGLSLNAARYALLRVEHGPPHTKNWRPQVLVMLNLDAEQAVKHPRLLSFTSQLKA
GKGLTIVGSVLEGTYLDKHMEAQRAEENIRSLMSTEKTKGFCQLVVSSSLRDGMSHLIQS
AGLGGLKHNTVLMAWPASWKQEDNPFSWKNFVDTVRDTTAAHQALLVAKNVDSFPQNQER
FGGGHIDVWWIVHDGGMLMLLPFLLRQHKVWRKCRMRIFTVAQVDDNSIQMKKDLQMFLY
HLRISAEVEVVEMVENDISAFTYERTLMMEQRSQMLKQMQLSKNEQEREAQLIHDRNTAS
HTAAAARTQAPPTPDKVQMTWTREKLIAEKYRSRDTSLSGFKDLFSMKPDQSNVRRMHTA
VKLNGVVLNKSQDAQLVLLNMPGPPKNRQGDENYMEFLEVLTEGLNRVLLVRGGGREVIT
IYS
NT seq 3252 nt   +upstreamnt  +downstreamnt
atgcccaccaacttcaccgtggtgcccgtggaggctcacgccgacggcggcggggacgag
actgccgagcggacggaggctccgggcacccccgagggccccgagcccgagcgccccagc
ccgggagatggaaatccaagagaaaacagcccattcctcaacaatgtcgaggtggaacaa
gagagcttctttgaagggaagaacatggcacttttcgaggaggagatggacagtaacccc
atggtgtcctcgctgctcaacaagctggccaactacaccaacctgagccagggcgtggtg
gagcacgaggaggacgaggagagccggcggcgggaggccaaggctccgcgcatgggcacc
ttcatcggcgtctacctgccgtgcctgcagaacatcctgggcgtcatcctcttcctgcgc
ctgacgtggatcgtgggggtggctggtgtcctggagtccttcctcatcgtggccatgtgc
tgcacatgtacaatgctgaccgccatttccatgagtgcgatcgctaccaacggtgtggtc
ccagctggcgggtcctactacatgatatcgcgctcgctgggacccgagtttggaggcgct
gtcggcctctgcttctacctgggcacgacgtttgcaggggccatgtatattttggggacc
atcgagatttttctgacgtacatctccccgggtgcggccatcttccaggcggaggctgca
ggtggcgaggcggccgccatgctgcacaacatgcgtgtgtacggcacgtgcacgctcgtg
ctcatggccctggtggtcttcgtgggcgtcaagtatgtcaacaagctggcgctggtcttc
ctggcctgcgtcgtgctgtccatcctggccatctatgccggcgtcatcaagtctgccttc
gaccccccggacatcccggtctgcctcctggggaaccgcacgctgtcacggcgcagcttc
gatgcctgcgtcaaggcctacggcatccacaacaactcagccacctccgcgctctggggc
ctcttctgcaacggctcccagcccagcgccgcctgtgacgagtacttcatccagaacaac
gtcaccgaaatccagggcatcccgggcgcggccagtggtgtcttcctggagaacctgtgg
agtacgtacgcgcacgcgggggcgtttgtggagaagaaaggtgtgccctcggtgcccgtg
gcagaggagagccgtgccagcgcactgccctacgtgctcaccgacatcgcggcctccttc
accctgctggttggcatctacttcccttccgtgaccggtatcatggcgggttcaaaccgg
tccggggacctcaaggatgcacagaagtccatccccacggggaccatcctggccatagtg
acgacgtctttcatctatctctcctgcattgtgctgtttggggcctgcattgaaggcgtg
gtcttacgagataagttcggggaggccctgcaggggaacctggtcatcggcatgctggcc
tggccctccccctgggtcatcgtcatcggctccttcttctccacctgcggtgccggcctg
cagagcctcacgggggcaccgcgcctactgcaggccattgcccgtgacggcatcgtcccc
ttcctgcaggtgtttggccacgggaaggccaacggggagcccacgtgggcgctgctgctg
acagtcctcatctgcgagactggcatcctcatcgcctctctggacagcgtggccccgatc
ctctccatgttcttcctcatgtgctacctgttcgtgaacctggcctgcgccgtgcagacc
ctgctacgtacccccaactggcgtccacgcttcaagttctaccactggaccctgtccttt
ctgggtatgagcctgtgcctggcgctgatgttcatctgctcctggtactacgcgctgtcc
gccatgctcatcgctggctgcatctacaagtacatcgagtaccgcggggccgagaaggag
tggggcgatggcatccgtggcctatccctgaacgccgcccgctacgccctgctgcgcgtg
gagcacggtcccccccacaccaagaactggaggccccaggtgctggtgatgctgaacctg
gacgcggagcaggccgtgaagcacccccgcctgctgtccttcacgtcgcagctgaaggcc
ggcaagggcctgaccatcgtgggctcggtgctggaggggacgtacctggacaagcacatg
gaggctcagcgggccgaggagaacatacggtccctaatgagcacagagaagaccaagggc
ttctgccagctggtggtctcgtccagcctgcgggatggcatgtcccacctgatccagtcg
gccggcctgggcggcctgaagcacaacacggtgctcatggcctggcccgcatcctggaag
caggaggacaaccccttctcctggaagaactttgtggacaccgtccgcgacaccaccgcc
gcgcaccaggctctgctggtggccaagaacgtcgactcgtttccgcaaaaccaggagcgc
ttcggcgggggccacatcgacgtgtggtggatcgtgcacgacggcggcatgctcatgctg
ctgcccttcctgctgcgccagcacaaggtgtggaggaagtgccggatgcgtatcttcacc
gtggcccaggtggacgacaacagcatccagatgaagaaggacctgcagatgttcttgtac
cacttgcgcatcagcgccgaggtggaggtggtggagatggttgaaaacgacatatctgct
ttcacctacgagaggacactaatgatggagcagaggtcgcagatgctgaagcagatgcag
ctgtccaagaacgagcaggagcgagaggcccagctgatccacgacaggaacaccgcgtcc
cacaccgcggcggcagccaggacccaagcgccgcctacgccagacaaggtgcagatgacc
tggaccagggagaagctgatcgctgagaagtacaggagcagagacaccagcctatctggt
ttcaaagacctcttcagcatgaagccggaccagtccaacgtcaggcggatgcacacggct
gtgaagctcaatggcgtcgtcctcaacaagtcccaggatgcgcagctggtcctgctcaac
atgccaggtcctcccaaaaaccggcagggagacgagaactacatggagtttcttgaagtc
ctgaccgaggggctgaacagagtcctcctggtcaggggtggcggccgggaggtgatcacc
atctactcctaa

  All links  
Disease (1)   
   OMIM (1)   
Gene (19)   
   RefGene (12)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (24)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (22)   
DNA sequence (57)   
   RefSeq(nuc) (31)   
   GenBank (13)   
   EMBL (13)   
3D Structure (1)   
   PDB (1)   
Protein domain (4)   
   Pfam (4)   
All databases (106)   

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