KEGG   Homo sapiens (human): 10800
Entry
10800             CDS       T01001                                 

Gene name
CYSLTR1, CYSLT1, CYSLT1R, CYSLTR, HMTMF81
Definition
(RefSeq) cysteinyl leukotriene receptor 1
  KO
K04322  cysteinyl leukotriene receptor 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
Drug target
Ablukast (DG01244): D02739 D02741
Cinalukast: D02846
Ibudilast: D01385<JP>
Montelukast (DG01066): D00529<JP/US> D08229
Pobilukast edamine: D02848
Pranlukast (DG01065): D02732<JP> D08408
Ritolukast: D02849
Sulukast: D02850
Tipelukast: D06659
Tomelukast: D02851
Verlukast: D02384
Zafirlukast: D00411<US>
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    10800 (CYSLTR1)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    10800 (CYSLTR1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    10800 (CYSLTR1)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Lipid
   Cysteinyl leukotriene
    10800 (CYSLTR1)
SSDB
Motif
Pfam: 7tm_1 7TM_GPCR_Srw 7TM_GPCR_Srx 7TM_GPCR_Srv DUF420 Shisa COX7C MscS_TM TMEM234
Other DBs
NCBI-GeneID: 10800
NCBI-ProteinID: NP_001269115
OMIM: 300201
HGNC: 17451
Ensembl: ENSG00000173198
Vega: OTTHUMG00000021889
Pharos: Q9Y271(Tclin)
UniProt: Q9Y271 Q38Q91 Q38Q88
Position
Xq21.1
AA seq 337 aa
MDETGNLTVSSATCHDTIDDFRNQVYSTLYSMISVVGFFGNGFVLYVLIKTYHKKSAFQV
YMINLAVADLLCVCTLPLRVVYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAMSFF
RCIAIVFPVQNINLVTQKKARFVCVGIWIFVILTSSPFLMAKPQKDEKNNTKCFEPPQDN
QTKNHVLVLHYVSLFVGFIIPFVIIIVCYTMIILTLLKKSMKKNLSSHKKAIGMIMVVTA
AFLVSFMPYHIQRTIHLHFLHNETKPCDSVLRMQKSVVITLSLAASNCCFDPLLYFFSGG
NFRKRLSTFRKHSLSSVTYVPRKKASLPEKGEEICKV
NT seq 1014 nt   +upstreamnt  +downstreamnt
atggatgaaacaggaaatctgacagtatcttctgccacatgccatgacactattgatgac
ttccgcaatcaagtgtattccaccttgtactctatgatctctgttgtaggcttctttggc
aatggctttgtgctctatgtcctcataaaaacctatcacaagaagtcagccttccaagta
tacatgattaatttagcagtagcagatctactttgtgtgtgcacactgcctctccgtgtg
gtctattatgttcacaaaggcatttggctctttggtgacttcttgtgccgcctcagcacc
tatgctttgtatgtcaacctctattgtagcatcttctttatgacagccatgagctttttc
cggtgcattgcaattgtttttccagtccagaacattaatttggttacacagaaaaaagcc
aggtttgtgtgtgtaggtatttggatttttgtgattttgaccagttctccatttctaatg
gccaaaccacaaaaagatgagaaaaataataccaagtgctttgagcccccacaagacaat
caaactaaaaatcatgttttggtcttgcattatgtgtcattgtttgttggctttatcatc
ccttttgttattataattgtctgttacacaatgatcattttgaccttactaaaaaaatca
atgaaaaaaaatctgtcaagtcataaaaaggctataggaatgatcatggtcgtgaccgct
gcctttttagtcagtttcatgccatatcatattcaacgtaccattcaccttcatttttta
cacaatgaaactaaaccctgtgattctgtccttagaatgcagaagtccgtggtcataacc
ttgtctctggctgcatccaattgttgctttgaccctctcctatatttcttttctgggggt
aactttaggaaaaggctgtctacattcagaaagcattctttgtccagcgtgacttatgta
cccagaaagaaggcctctttgccagaaaaaggagaagaaatatgtaaagtatag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Drug (15)   
   KEGG DRUG (15)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (8)   
   UniProt (3)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (24)   
   RefSeq(nuc) (4)   
   GenBank (10)   
   EMBL (10)   
Protein domain (9)   
   Pfam (9)   
All databases (81)   

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KEGG   Homo sapiens (human): 57105
Entry
57105             CDS       T01001                                 

Gene name
CYSLTR2, CYSLT2, CYSLT2R, GPCR21, HG57, HPN321, KPG_011, PSEC0146, hGPCR21
Definition
(RefSeq) cysteinyl leukotriene receptor 2
  KO
K04323  cysteinyl leukotriene receptor 2
Organism
hsa  Homo sapiens (human)
Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    57105 (CYSLTR2)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    57105 (CYSLTR2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    57105 (CYSLTR2)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Lipid
   Cysteinyl leukotriene
    57105 (CYSLTR2)
SSDB
Motif
Pfam: 7tm_1 TAS2R 7TM_GPCR_Srx
Other DBs
NCBI-GeneID: 57105
NCBI-ProteinID: NP_001295394
OMIM: 605666
HGNC: 18274
Ensembl: ENSG00000152207
Vega: OTTHUMG00000016906
Pharos: Q9NS75(Tchem)
UniProt: Q9NS75 Q5KU17 A4ZKH2
Position
13q14.2
AA seq 346 aa
MERKFMSLQPSISVSEMEPNGTFSNNNSRNCTIENFKREFFPIVYLIIFFWGVLGNGLSI
YVFLQPYKKSTSVNVFMLNLAISDLLFISTLPFRADYYLRGSNWIFGDLACRIMSYSLYV
NMYSSIYFLTVLSVVRFLAMVHPFRLLHVTSIRSAWILCGIIWILIMASSIMLLDSGSEQ
NGSVTSCLELNLYKIAKLQTMNYIALVVGCLLPFFTLSICYLLIIRVLLKVEVPESGLRV
SHRKALTTIIITLIIFFLCFLPYHTLRTVHLTTWKVGLCKDRLHKALVITLALAAANACF
NPLLYYFAGENFKDRLKSALRKGHPQKAKTKCVFPVSVWLRKETRV
NT seq 1041 nt   +upstreamnt  +downstreamnt
atggagagaaaatttatgtccttgcaaccatccatctccgtatcagaaatggaaccaaat
ggcaccttcagcaataacaacagcaggaactgcacaattgaaaacttcaagagagaattt
ttcccaattgtatatctgataatatttttctggggagtcttgggaaatgggttgtccata
tatgttttcctgcagccttataagaagtccacatctgtgaacgttttcatgctaaatctg
gccatttcagatctcctgttcataagcacgcttcccttcagggctgactattatcttaga
ggctccaattggatatttggagacctggcctgcaggattatgtcttattccttgtatgtc
aacatgtacagcagtatttatttcctgaccgtgctgagtgttgtgcgtttcctggcaatg
gttcacccctttcggcttctgcatgtcaccagcatcaggagtgcctggatcctctgtggg
atcatatggatccttatcatggcttcctcaataatgctcctggacagtggctctgagcag
aacggcagtgtcacatcatgcttagagctgaatctctataaaattgctaagctgcagacc
atgaactatattgccttggtggtgggctgcctgctgccatttttcacactcagcatctgt
tatctgctgatcattcgggttctgttaaaagtggaggtcccagaatcggggctgcgggtt
tctcacaggaaggcactgaccaccatcatcatcaccttgatcatcttcttcttgtgtttc
ctgccctatcacacactgaggaccgtccacttgacgacatggaaagtgggtttatgcaaa
gacagactgcataaagctttggttatcacactggccttggcagcagccaatgcctgcttc
aatcctctgctctattactttgctggggagaattttaaggacagactaaagtctgcactc
agaaaaggccatccacagaaggcaaagacaaagtgtgttttccctgttagtgtgtggttg
agaaaggaaacaagagtataa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (22)   
   KEGG ORTHOLOGY (1)   
   RefGene (14)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (15)   
   UniProt (3)   
   SWISS-PROT (1)   
   RefSeq(pep) (11)   
DNA sequence (39)   
   RefSeq(nuc) (11)   
   GenBank (14)   
   EMBL (14)   
Protein domain (3)   
   Pfam (3)   
All databases (85)   

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