| Entry |
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| Gene name |
CGA, CG-ALPHA, FSHA, GPA1, GPHA1, GPHa, HCG, LHA, TSHA
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| Definition |
(RefSeq) glycoprotein hormones, alpha polypeptide
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| KO |
| K08522 | glycoprotein hormones alpha chain |
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| Organism |
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04923 | Regulation of lipolysis in adipocytes |
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| Network |
nt06323 KISS1-GnRH-LH/FSH-E2 signaling nt06361 Hypogonadotropic hypogonadism |
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| Element |
| N00873 | GnRH-GnRHR-PLCB-PKC signaling pathway |
| N00875 | Mutation-inactivated GnRHR to GnRH-GnRHR-PLCB-PKC signaling pathway |
| N00885 | LHCGR-GNAS-PKA signaling pathway |
| N00886 | Mutation-activated LHCGR to LHCGR-GNAS-PKA signaling pathway |
| N00922 | FSHR-GNAS-PKA signaling pathway |
| N00923 | Mutation-inactivated FSHB to FSHR-GNAS-PKA signaling pathway |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
1081 (CGA)
09133 Signaling molecules and interaction
04080 Neuroactive ligand-receptor interaction
1081 (CGA)
09150 Organismal Systems
09152 Endocrine system
04923 Regulation of lipolysis in adipocytes
1081 (CGA)
04929 GnRH secretion
1081 (CGA)
04912 GnRH signaling pathway
1081 (CGA)
04913 Ovarian steroidogenesis
1081 (CGA)
04917 Prolactin signaling pathway
1081 (CGA)
04918 Thyroid hormone synthesis
1081 (CGA)
09160 Human Diseases
09163 Immune disease
05320 Autoimmune thyroid disease
1081 (CGA)
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
PDB: |
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| Position |
6q14.3
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| AA seq |
116 aa
MDYYRKYAAIFLVTLSVFLHVLHSAPDVQDCPECTLQENPFFSQPGAPILQCMGCCFSRA
YPTPLRSKKTMLVQKNVTSESTCCVAKSYNRVTVMGGFKVENHTACHCSTCYYHKS |
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| NT seq |
351 nt +upstreamnt +downstreamnt
atggattactacagaaaatatgcagctatctttctggtcacattgtcggtgtttctgcat
gttctccattccgctcctgatgtgcaggattgcccagaatgcacgctacaggaaaaccca
ttcttctcccagccgggtgccccaatacttcagtgcatgggctgctgcttctctagagca
tatcccactccactaaggtccaagaagacgatgttggtccaaaagaacgtcacctcagag
tccacttgctgtgtagctaaatcatataacagggtcacagtaatggggggtttcaaagtg
gagaaccacacggcgtgccactgcagtacttgttattatcacaaatcttaa |
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