KEGG   Homo sapiens (human): 10810
Entry
10810             CDS       T01001                                 

Gene name
WASF3, Brush-1, SCAR3, WAVE3
Definition
(RefSeq) WASP family member 3
  KO
K06083  WAS protein family, member 3
Organism
hsa  Homo sapiens (human)
Pathway
hsa04520  Adherens junction
hsa04666  Fc gamma R-mediated phagocytosis
hsa05130  Pathogenic Escherichia coli infection
hsa05132  Salmonella infection
hsa05231  Choline metabolism in cancer
Network
nt06135  Cytoskeletal regulation (viruses and bacteria)
  Element
N01066  ARNO-ARF-ACTB_G signaling pathway
N01067  Shigella IpgD to ARNO-ARF-ACTB_G signaling pathway
N01128  Salmonella SopE to RAC signaling pathway
N01129  Salmonella SopB to ARNO-ARF-ACTB/G signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    10810 (WASF3)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    10810 (WASF3)
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    10810 (WASF3)
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    10810 (WASF3)
   05132 Salmonella infection
    10810 (WASF3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    10810 (WASF3)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    WASP / WAVE
     10810 (WASF3)
SSDB
Motif
Pfam: WH2 ChaB
Other DBs
NCBI-GeneID: 10810
NCBI-ProteinID: NP_006637
OMIM: 605068
HGNC: 12734
Ensembl: ENSG00000132970
Vega: OTTHUMG00000016621
Pharos: Q9UPY6(Tbio)
UniProt: Q9UPY6 Q5T8P4
Position
13q12.13
AA seq 502 aa
MPLVKRNIEPRHLCRGALPEGITSELECVTNSTLAAIIRQLSSLSKHAEDIFGELFNEAN
NFYIRANSLQDRIDRLAVKVTQLDSTVEEVSLQDINMKKAFKSSTVQDQQVVSKNSIPNP
VADIYNQSDKPPPLNILTPYRDDKKDGLKFYTDPSYFFDLWKEKMLQDTEDKRKEKRRQK
EQKRIDGTTREVKKVRKARNRRQEWNMMAYDKELRPDNRLSQSVYHGASSEGSLSPDTRS
HASDVTDYSYPATPNHSLHPQPVTPSYAAGDVPPHGPASQAAEHEYRPPSASARHMALNR
PQQPPPPPPPQAPEGSQASAPMAPADYGMLPAQIIEYYNPSGPPPPPPPPVIPSAQTAFV
SPLQMPMQPPFPASASSTHAAPPHPPSTGLLVTAPPPPGPPPPPPGPPGPGSSLSSSPMH
GPPVAEAKRQEPAQPPISDARSDLLAAIRMGIQLKKVQEQREQEAKREPVGNDVATILSR
RIAVEYSDSDDDSEFDENDWSD
NT seq 1509 nt   +upstreamnt  +downstreamnt
atgcctttagtgaagaggaacattgagccccggcacttgtgccggggagctctgcctgaa
gggattaccagcgaacttgaatgtgtaaccaatagtactcttgccgctatcatacgccag
ctgagcagtctgagcaaacatgctgaagacatatttggtgagttgtttaatgaggctaac
aacttctacatcagagcaaattctcttcaagacagaattgatcgccttgctgtcaaagtc
acccagctggattcaacagtggaagaggtctcactacaggatatcaacatgaaaaaagct
ttcaaaagttccacagtccaagaccagcaagtggtttcaaagaacagcattcctaatcct
gttgctgatatttacaaccagagtgataagccaccgcctctgaacatcctgacaccatac
agagatgacaagaaggatgggctgaagttctatactgatccttcctatttctttgacctc
tggaaagaaaaaatgctacaggacacagaagacaaaaggaaagagaaaaggcgtcaaaag
gagcaaaagcgtatagatggcaccacccgtgaggtgaaaaaggttagaaaagccagaaac
aggcgccaggagtggaatatgatggcatatgacaaagagcttagacccgacaacaggttg
tctcagagtgtgtaccatggagcgtcttccgagggatccctgtccccagatactaggtca
catgcatcggacgttacggattactcttacccggctactcccaaccattctctgcacccc
cagcctgtgaccccttcctatgcagctggtgacgtgccaccacacgggcctgcaagccag
gctgcggagcatgagtaccggcccccatctgcctcggcgaggcacatggccctcaacaga
cctcagcagccgccccccccgcctccccctcaggccccagaggggtcccaggcctctgca
ccgatggctccagcagactacgggatgctcccagcgcagataattgagtattacaaccca
tccggaccacctcctccgccacctcctcctgtgattccctcagcacaaactgccttcgtc
agccctctccagatgcccatgcagcccccgttccctgcatcagccagctccacgcacgca
gctcctcctcacccaccctccaccgggctcctggtcacagccccgccacccccgggccca
ccacctcccccgccaggccctcctggtcccgggtcttctctttcgtcctccccaatgcat
ggccccccagtagctgaggcgaagcggcaagagcctgcacagccaccaatcagtgatgct
cgaagcgacctcctcgctgctattcgaatgggaattcaactgaaaaaggtgcaggagcag
cgggagcaggaggccaagcgggagccagtggggaatgacgtggccacgatcctgtcccgg
cgcattgccgtggagtacagcgactctgacgacgactcagagttcgacgagaacgactgg
tccgactga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (5)   
Network (4)   
   KEGG NETWORK (4)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (26)   
   KEGG ORTHOLOGY (1)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (11)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (8)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (25)   
   RefSeq(nuc) (5)   
   GenBank (10)   
   EMBL (10)   
Protein domain (2)   
   Pfam (2)   
All databases (74)   

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