KEGG   Homo sapiens (human): 10905
Entry
10905             CDS       T01001                                 
Symbol
MAN1A2, MAN1B
Name
(RefSeq) mannosidase alpha class 1A member 2
  KO
K01230  mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00510  N-Glycan biosynthesis
hsa00513  Various types of N-glycan biosynthesis
hsa01100  Metabolic pathways
hsa04141  Protein processing in endoplasmic reticulum
Module
hsa_M00073  N-glycan precursor trimming
Network
nt06015  N-Glycan biosynthesis
  Element
N00820  N-Glycan biosynthesis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00510 N-Glycan biosynthesis
    10905 (MAN1A2)
   00513 Various types of N-glycan biosynthesis
    10905 (MAN1A2)
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    10905 (MAN1A2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    10905 (MAN1A2)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.2  Glycosylases
   3.2.1  Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
    3.2.1.113  mannosyl-oligosaccharide 1,2-alpha-mannosidase
     10905 (MAN1A2)
Membrane trafficking [BR:hsa04131]
 Endoplasmic reticulum (ER) - Golgi transport
  Forward pathways
   ER-Golgi intermediate compartment (ERGIC) proteins
    10905 (MAN1A2)
SSDB
Motif
Pfam: Glyco_hydro_47 iSTAND POP1_C
Other DBs
NCBI-GeneID: 10905
NCBI-ProteinID: NP_006690
OMIM: 604345
HGNC: 6822
Ensembl: ENSG00000198162
UniProt: O60476
Position
1:117367449..117528872
AA seq 641 aa
MTTPALLPLSGRRIPPLNLGPPSFPHHRATLRLSEKFILLLILSAFITLCFGAFFFLPDS
SKHKRFDLGLEDVLIPHVDAGKGAKNPGVFLIHGPDEHRHREEEERLRNKIRADHEKALE
EAKEKLRKSREEIRAEIQTEKNKVVQEMKIKENKPLPPVPIPNLVGIRGGDPEDNDIREK
REKIKEMMKHAWDNYRTYGWGHNELRPIARKGHSPNIFGSSQMGATIVDALDTLYIMGLH
DEFLDGQRWIEDNLDFSVNSEVSVFEVNIRFIGGLLAAYYLSGEEIFKIKAVQLAEKLLP
AFNTPTGIPWAMVNLKSGVGRNWGWASAGSSILAEFGTLHMEFIHLSYLTGDLTYYKKVM
HIRKLLQKMDRPNGLYPNYLNPRTGRWGQYHTSVGGLGDSFYEYLLKAWLMSDKTDHEAR
KMYDDAIEAIEKHLIKKSRGGLTFIGEWKNGHLEKKMGHLACFAGGMFALGADGSRADKA
GHYLELGAEIARTCHESYDRTALKLGPESFKFDGAVEAVAVRQAEKYYILRPEVIETYWY
LWRFTHDPRYRQWGWEAALAIEKYCRVNGGFSGVKDVYSSTPTHDDVQQSFFLAETLKYL
YLLFSGDDLLPLDHWVFNTEAHPLPVLHLANTTLSGNPAVR
NT seq 1926 nt   +upstreamnt  +downstreamnt
atgactaccccagccctgctgcccctctctggacgtaggataccacctctgaacctgggg
ccgccttccttcccacatcacagggctaccttgagactttctgagaagtttattcttctc
cttattcttagtgccttcatcactctgtgttttggggcattctttttccttccagactct
tcaaaacacaaacgctttgatttgggtttagaagatgtgttaattccacatgtagatgcc
ggtaaaggggctaaaaaccccggagtcttcctgatccatggacccgatgaacatagacac
agggaagaggaagaacgtctgagaaataaaattcgagctgatcatgagaaggccttggaa
gaagcaaaagaaaaattaagaaagtcaagagaggaaattcgagcagaaattcagacagag
aaaaataaggtagtccaagaaatgaagataaaagagaacaagccactgccaccagtccct
attcccaaccttgtaggaatacgtggtggagacccagaagataatgacataagagagaaa
agggaaaaaattaaagagatgatgaaacatgcttgggataactataggacatatgggtgg
ggacataatgaactcagacctattgcaaggaaaggacactcccctaacatatttggaagt
tcacaaatgggtgctaccatagtagatgctttggataccctttatatcatgggacttcat
gatgaattcctagatgggcaaagatggattgaagacaaccttgatttcagtgtgaattca
gaggtgtctgtgtttgaagtcaacattcgatttattggaggcctacttgcagcatattac
ctatcaggagaggagatattcaagattaaagcagtgcaattggctgagaaactccttcct
gcctttaacacacctactgggattccttgggcaatggtgaatttgaaaagtggagtaggg
cgaaactggggctgggcatctgcaggtagcagcattctggctgaatttggtacactacat
atggagttcatccacctcagctacttgacaggggacctgacttactacaaaaaggttatg
cacattcggaaactacttcagaaaatggatcgtccaaatggtctttatccaaattatttg
aaccccagaacagggcgctggggtcagtatcatacatctgtcggtggcctgggagacagt
ttttatgaatacttactgaaagcatggttgatgtcagataaaacagaccatgaggcaaga
aagatgtatgatgatgctattgaggctatagaaaaacatcttattaagaagtctcgtgga
ggtcttacctttattggagaatggaagaatgggcacttggaaaaaaagatggggcatttg
gcctgctttgctgggggaatgtttgcactaggagcagatggttccagagcagataaagct
ggtcattatttagagctaggggcagaaattgcacgtacttgtcatgagtcatatgacaga
actgcattaaagctaggtcctgaatcattcaagtttgatggtgcagtggaggctgtggct
gtccggcaggctgaaaagtattatatcctccgtccagaagtaattgaaacctattggtac
ctatggcgattcactcacgatccaagatacaggcagtggggctgggaagcagcactggcc
attgaaaagtattgccgagttaatggtgggttttctggagtcaaagatgtatattcctct
actcctacacatgatgatgtacagcagagcttttttcttgctgaaacattaaaatatttg
tatctgctgttctccggtgatgaccttttacctttagaccactgggtgtttaatacagag
gctcaccctctgcctgtgttacatttagccaacaccacactttcaggtaatcctgctgtt
cgatga

  All links  
Disease (1)   
   OMIM (1)   
Gene (15)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (9)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (7)   
DNA sequence (29)   
   RefSeq(nuc) (7)   
   GenBank (11)   
   EMBL (11)   
Protein domain (3)   
   Pfam (3)   
All databases (57)   

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