KEGG   Homo sapiens (human): 11005
Entry
11005             CDS       T01001                                 
Symbol
SPINK5, LEKTI, LETKI, NETS, NS, VAKTI
Name
(RefSeq) serine peptidase inhibitor Kazal type 5
  KO
K23420  serine protease inhibitor Kazal-type 5
Organism
hsa  Homo sapiens (human)
Disease
H00671  Netherton syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    11005 (SPINK5)
Peptidases and inhibitors [BR:hsa01002]
 Peptidase inhibitors
  Family I1: Kazal family
   11005 (SPINK5)
SSDB
Motif
Pfam: Kazal_1 Kazal_2 CFAI_KAZAL RIOX1_C_WH
Other DBs
NCBI-GeneID: 11005
NCBI-ProteinID: NP_006837
OMIM: 605010
HGNC: 15464
Ensembl: ENSG00000133710
UniProt: Q9NQ38
Structure
Position
5:148063980..148137382
AA seq 1064 aa
MKIATVSVLLPLALCLIQDAASKNEDQEMCHEFQAFMKNGKLFCPQDKKFFQSLDGIMFI
NKCATCKMILEKEAKSQKRARHLARAPKATAPTELNCDDFKKGERDGDFICPDYYEAVCG
TDGKTYDNRCALCAENAKTGSQIGVKSEGECKSSNPEQDVCSAFRPFVRDGRLGCTREND
PVLGPDGKTHGNKCAMCAELFLKEAENAKREGETRIRRNAEKDFCKEYEKQVRNGRLFCT
RESDPVRGPDGRMHGNKCALCAEIFKQRFSEENSKTDQNLGKAEEKTKVKREIVKLCSQY
QNQAKNGILFCTRENDPIRGPDGKMHGNLCSMCQAYFQAENEEKKKAEARARNKRESGKA
TSYAELCSEYRKLVRNGKLACTRENDPIQGPDGKVHGNTCSMCEVFFQAEEEEKKKKEGK
SRNKRQSKSTASFEELCSEYRKSRKNGRLFCTRENDPIQGPDGKMHGNTCSMCEAFFQQE
ERARAKAKREAAKEICSEFRDQVRNGTLICTREHNPVRGPDGKMHGNKCAMCASVFKLEE
EEKKNDKEEKGKVEAEKVKREAVQELCSEYRHYVRNGRLPCTRENDPIEGLDGKIHGNTC
SMCEAFFQQEAKEKERAEPRAKVKREAEKETCDEFRRLLQNGKLFCTRENDPVRGPDGKT
HGNKCAMCKAVFQKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECAEYREQMKNGRLS
CTRESDPVRDADGKSYNNQCTMCKAKLEREAERKNEYSRSRSNGTGSESGKDTCDEFRSQ
MKNGKLICTRESDPVRGPDGKTHGNKCTMCKEKLEREAAEKKKKEDEDRSNTGERSNTGE
RSNDKEDLCREFRSMQRNGKLICTRENNPVRGPYGKMHINKCAMCQSIFDREANERKKKD
EEKSSSKPSNNAKDECSEFRNYIRNNELICPRENDPVHGADGKFYTNKCYMCRAVFLTEA
LERAKLQEKPSHVRASQEEDSPDSFSSLDSEMCKDYRVLPRIGYLCPKDLKPVCGDDGQT
YNNPCMLCHENLIRQTNTHIRSTGKCEESSTPGTTAASMPPSDE
NT seq 3195 nt   +upstreamnt  +downstreamnt
atgaagatagccacagtgtcagtgcttctgcccttggctctttgcctcatacaagatgct
gccagtaagaatgaagatcaggaaatgtgccatgaatttcaggcatttatgaaaaatgga
aaactgttctgtccccaggataagaaattttttcaaagtcttgatggaataatgttcatc
aataaatgtgccacgtgcaaaatgatactggaaaaagaagcaaaatcacagaagagggcc
aggcatttagcaagagctcccaaggctactgccccaacagagctgaattgtgatgatttt
aaaaaaggagaaagagatggggattttatctgtcctgattattatgaagctgtttgtggc
acagatgggaaaacatatgacaacagatgtgcactgtgtgctgagaatgcgaaaaccggg
tcccaaattggtgtaaaaagtgaaggggaatgtaagagcagtaatccagagcaggatgta
tgcagtgcttttcggccctttgttagagatggaagacttggatgcacaagggaaaatgat
cctgttcttggtcctgatgggaagacgcatggcaataagtgtgcaatgtgtgctgagctg
tttttaaaagaagctgaaaatgccaagcgagagggtgaaactagaattcgacgaaatgct
gaaaaggatttttgcaaggaatatgaaaaacaagtgagaaatggaaggcttttttgtaca
cgggagagtgatccagtccgtggccctgacggcaggatgcatggcaacaaatgtgccctg
tgtgctgaaattttcaagcagcgtttttcagaggaaaacagtaaaacagatcaaaatttg
ggaaaagctgaagaaaaaactaaagttaaaagagaaattgtgaaactctgcagtcaatat
caaaatcaggcaaagaatggaatacttttctgtaccagagaaaatgaccctattcgtggt
ccagatgggaaaatgcatggcaacttgtgttccatgtgtcaagcctacttccaagcagaa
aatgaagaaaagaaaaaggctgaagcacgagctagaaacaaaagagaatctggaaaagca
acctcatatgcagagctttgcagtgaatatcgaaagcttgtgaggaacggaaaacttgct
tgcaccagagagaacgatcctatccagggcccagatgggaaagtgcatggcaacacctgc
tccatgtgtgaggtcttcttccaagcagaagaagaagaaaagaaaaagaaggaaggtaaa
tcaagaaacaaaagacaatctaagagtacagcttcctttgaggagttgtgtagtgaatac
cgcaaatccaggaaaaacggacggcttttttgcaccagagagaatgaccccatccagggc
ccagatggaaaaatgcatggcaacacctgctccatgtgtgaggccttctttcaacaagaa
gaaagagcaagagcaaaggctaaaagagaagctgcaaaggaaatctgcagtgaatttcgg
gaccaagtgaggaatggaacacttatatgcaccagggagcataatcctgtccgtggccca
gatggcaaaatgcatggaaacaagtgtgccatgtgtgccagtgtgttcaaacttgaagaa
gaagagaagaaaaatgataaagaagaaaaagggaaagtcgaggctgaaaaagttaagaga
gaagcagttcaggagctgtgcagtgaatatcgtcattatgtgaggaatggacgactcccc
tgtaccagagagaatgatcctattgagggtctagatgggaaaatccacggcaacacctgc
tccatgtgtgaagccttcttccagcaagaagcaaaagaaaaagaaagagctgaacccaga
gcaaaagtcaaaagagaagctgaaaaggagacatgcgatgaatttcggagacttttgcaa
aatggaaaacttttctgcacaagagaaaatgatcctgtgcgtggcccagatggcaagacc
catggcaacaagtgtgccatgtgtaaggcagtcttccagaaagaaaatgaggaaagaaag
aggaaagaagaggaagatcagagaaatgctgcaggacatggttccagtggtggtggagga
ggaaacactcaggacgaatgtgctgagtatcgggaacaaatgaaaaatggaagactcagc
tgtactcgggagagtgatcctgtacgtgatgctgatggcaaatcgtacaacaatcagtgt
accatgtgtaaagcaaaattggaaagagaagcagagagaaaaaatgagtattctcgctcc
agatcaaatgggactggatcagaatcagggaaggatacatgtgatgagtttagaagccaa
atgaaaaatggaaaactcatctgcactcgagaaagtgaccctgtccggggtccagatggc
aagacacatggcaataagtgtactatgtgtaaggaaaaactggaaagggaagcagctgaa
aaaaaaaagaaagaggatgaagacaggagcaatacaggagaaaggagcaatacaggagaa
aggagcaatgacaaagaggatctgtgtcgtgaatttcgaagcatgcagagaaatggaaag
cttatctgcaccagagaaaataaccctgttcgaggcccatatggcaagatgcacatcaat
aaatgtgctatgtgtcagagcatctttgatcgagaagctaatgaaagaaaaaagaaagat
gaagagaaatcaagtagcaagccctcaaataatgcaaaggatgagtgcagtgaatttcga
aactatataaggaacaatgaactcatctgccctagagagaatgacccagtgcacggtgct
gatggaaagttctatacaaacaagtgctacatgtgcagagctgtctttctaacagaagct
ttggaaagggcaaagcttcaagaaaagccatcccatgttagagcttctcaagaggaagac
agcccagactctttcagttctctggattctgagatgtgcaaagactaccgagtattgccc
aggataggttatctttgtccaaaggatttaaagcctgtctgtggtgacgatggccaaacc
tacaacaatccttgcatgctctgtcatgaaaacctgatacgccaaacaaatacacacatc
cgcagtacagggaagtgtgaggagagcagcaccccaggaaccaccgcagccagcatgccc
ccgtctgacgaatga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (23)   
   KEGG ORTHOLOGY (1)   
   RefGene (16)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
   PHAROS (1)   
Protein sequence (9)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (7)   
DNA sequence (39)   
   RefSeq(nuc) (7)   
   GenBank (16)   
   EMBL (16)   
3D Structure (6)   
   PDB (6)   
Protein domain (4)   
   Pfam (4)   
All databases (87)   

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