KEGG   Homo sapiens (human): 11044
Entry
11044             CDS       T01001                                 
Symbol
TENT4A, LAK-1, LAK1, PAPD7, POLK, POLS, TRF4, TRF4-1, TRF41, TUTASE5
Name
(RefSeq) terminal nucleotidyltransferase 4A
  KO
K03514  non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
Organism
hsa  Homo sapiens (human)
Pathway
hsa03018  RNA degradation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   03018 RNA degradation
    11044 (TENT4A)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    11044 (TENT4A)
   03016 Transfer RNA biogenesis [BR:hsa03016]
    11044 (TENT4A)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.7  Nucleotidyltransferases
    2.7.7.19  polynucleotide adenylyltransferase
     11044 (TENT4A)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA degradation factors
   3'-5' decay
    TRAMP complex
     11044 (TENT4A)
Transfer RNA biogenesis [BR:hsa03016]
 Eukaryotic type
  tRNA degradation factors
   TRAMP complex
    11044 (TENT4A)
SSDB
Motif
Pfam: MTPAP-like_central PAP_assoc NTP_transf_2 Polbeta TUTase PAP_NTPase
Other DBs
NCBI-GeneID: 11044
NCBI-ProteinID: NP_008930
OMIM: 605198
HGNC: 16705
Ensembl: ENSG00000112941
UniProt: Q5XG87 A0A9H4DBI9 B7ZLL4
Position
5:6713432..6757044
AA seq 792 aa
MDPRVAWIQPEQKGPANALWMQIWETSQGVGRGGSGFASYFCLNSPALDTAAAAGAAGRG
SGGLGPALPAASPPPPGPTAPAALPPALLTALGPAAEGARRLHKSPSLSSSSSSSSSNAE
SGTESPGCSSSSSSSASLGRPGGGRGGAFFNFADGAPSAPGTANGHPGPRGPAPAGSPSQ
HQFHPGRRKRENKASTYGLNYLLSGSRAAALSGGGGPGAQAPRPGTPWKSRAYSPGIQGL
HEEIIDFYNFMSPCPEEAAMRREVVKRIETVVKDLWPTADVQIFGSFSTGLYLPTSDIDL
VVFGKWERPPLQLLEQALRKHNVAEPCSIKVLDKATVPIIKLTDQETEVKVDISFNMETG
VRAAEFIKNYMKKYSLLPYLILVLKQFLLQRDLNEVFTGGISSYSLILMAISFLQLHPRI
DARRADENLGMLLVEFFELYGRNFNYLKTGIRIKEGGAYIAKEEIMKAMTSGYRPSMLCI
EDPLLPGNDVGRSSYGAMQVKQVFDYAYIVLSHAVSPLARSYPNRDAESTLGRIIKVTQE
VIDYRRWIKEKWGSKAHPSPGMDSRIKIKERIATCNGEQTQNREPESPYGQRLTLSLSSP
QLLSSGSSASSVSSLSGSDVDSDTPPCTTPSVYQFSLQAPAPLMAGLPTALPMPSGKPQP
TTSRTLIMTTNNQTRFTIPPPTLGVAPVPCRQAGVEGTASLKAVHHMSSPAIPSASPNPL
SSPHLYHKQHNGMKLSMKGSHGHTQGGGYSSVGSGGVRPPVGNRGHHQYNRTGWRRKKHT
HTRDSLPVSLSR
NT seq 2379 nt   +upstreamnt  +downstreamnt
atggatccgcgcgtggcctggatccagcccgagcagaaggggccggccaatgccctgtgg
atgcagatctgggagacctcgcagggcgtgggccgcggcggctcgggcttcgcgtcctat
ttctgcctcaactcgccggcgctggacacggcggccgcggcgggggcggccgggcggggc
agtggcggcctgggccccgcgctgcccgccgcgtcgcccccgccgcccggccccaccgcg
cccgccgcgctgccccccgcgctgctgacggcgctggggcccgcggccgagggcgcgcgg
cgcttgcacaagtcgccgtcgctgtcgtcctcgtcgtcgtcctcctcgtccaacgcggag
tcgggcaccgagagccccggctgctcgtcgtcgtcctccagcagcgcctcgctgggccgg
ccgggcggcggccgcggcggcgccttcttcaacttcgccgacggcgcgcccagcgcccct
ggcacagccaacgggcaccccgggccgcgcggccccgcgcccgccggctccccgtcgcag
caccagttccacccgggtcgccggaaacgcgagaacaaggccagcacctacggcctcaac
tacctgctgtccggcagccgcgcggccgctctcagcggagggggcggccccggggcccag
gcgccgcggcccggcaccccgtggaagagccgcgcgtacagcccgggcatccagggacta
catgaggaaataattgacttttataacttcatgtccccttgtcctgaagaagcagctatg
agaagagaggtggtgaaacggatcgaaactgtggtgaaagacctttggccgacggctgat
gtacagatatttggcagctttagtacaggtctttatcttccaactagcgacatagacctg
gtggtcttcgggaaatgggagcgtcctcctttacagctgctggagcaagccctgcggaag
cacaacgtggctgagccgtgttccatcaaagtccttgacaaggctacggtaccaataata
aagctcacagatcaggagactgaagtgaaagttgacatcagctttaacatggagacgggc
gtccgggcagcggagttcatcaagaattacatgaagaaatattcattgctgccttacttg
attttagtattgaaacagttccttctgcagagggacctgaatgaagtttttacaggtgga
attagctcatacagcctaattttaatggccattagctttctacagttgcatccaagaatt
gatgcccggagagctgatgaaaaccttggaatgcttcttgtagaattttttgaactctat
gggagaaattttaattacttgaaaaccggtattagaatcaaagaaggaggtgcctatatc
gccaaagaggagatcatgaaagccatgaccagcgggtacagaccgtcgatgctgtgcatt
gaggaccccctgctgccagggaatgacgttggccggagctcctatggcgccatgcaggtg
aagcaggtcttcgattatgcctacatagtgctcagccatgctgtgtcaccgctggccagg
tcctatccaaacagagacgccgaaagtactttaggaagaatcatcaaagtaactcaggag
gtgattgactaccggaggtggatcaaagagaagtggggcagcaaagcccacccgtcgcca
ggcatggacagcaggatcaagatcaaagagcgaatagccacatgcaatggggagcagacg
cagaaccgagagcccgagtctccctatggccagcgcttgactttgtcgctgtccagcccc
cagctcctgtcttcaggctcctcggcctcttctgtgtcttcactttctgggagtgacgtt
gattcagacacaccgccctgcacaacgcccagtgtttaccagttcagtctgcaagcgcca
gctcctctcatggccggcttacccaccgccttgccaatgcccagtggcaaacctcagccc
accacttccagaacactgatcatgacaaccaacaatcagaccaggtttactatacctcca
ccgaccctaggggttgctcctgttccttgcagacaagctggtgtagaaggaactgcgtct
ttgaaagccgtccaccacatgtcttccccggccattccctcagcgtcccccaacccgctc
tcgagccctcatctgtatcataagcagcacaacggcatgaaactgtccatgaagggctct
cacggccacacccaaggcggcggctacagctctgtgggtagcggaggtgtgcggccccct
gtgggcaacaggggacaccaccagtataaccgcaccggctggaggaggaaaaaacacaca
cacacacgggacagtctgcccgtgagcctcagcagataa

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