KEGG   Homo sapiens (human): 11093
Entry
11093             CDS       T01001                                 

Gene name
ADAMTS13, ADAM-TS13, ADAMTS-13, C9orf8, VWFCP, vWF-CP
Definition
(RefSeq) ADAM metallopeptidase with thrombospondin type 1 motif 13
  KO
K08627  a disintegrin and metalloproteinase with thrombospondin motifs 13 [EC:3.4.24.87]
Organism
hsa  Homo sapiens (human)
Disease
H00225  Thrombotic thrombocytopenic purpura
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    11093 (ADAMTS13)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
    3.4.24.87  ADAMTS13 endopeptidase
     11093 (ADAMTS13)
Peptidases and inhibitors [BR:hsa01002]
 Metallo peptidases
  Family M12: astacin/adamalysin family
   11093 (ADAMTS13)
SSDB
Motif
Pfam: ADAM_CR_3 TSP1_ADAMTS ADAM_spacer1 TSP_1 ADAM_CR_2 Reprolysin Reprolysin_4 Reprolysin_3 TSP1_spondin Reprolysin_5 Peptidase_M10 Reprolysin_2 TSP1_CCN
Other DBs
NCBI-GeneID: 11093
NCBI-ProteinID: NP_620594
OMIM: 604134
HGNC: 1366
Ensembl: ENSG00000160323
Vega: OTTHUMG00000020876
Pharos: Q76LX8(Tbio)
UniProt: Q76LX8
Structure
PDB: 
3GHM 6QIG 3VN4 3GHN

Position
9q34.2
AA seq 1427 aa
MHQRHPRARCPPLCVAGILACGFLLGCWGPSHFQQSCLQALEPQAVSSYLSPGAPLKGRP
PSPGFQRQRQRQRRAAGGILHLELLVAVGPDVFQAHQEDTERYVLTNLNIGAELLRDPSL
GAQFRVHLVKMVILTEPEGAPNITANLTSSLLSVCGWSQTINPEDDTDPGHADLVLYITR
FDLELPDGNRQVRGVTQLGGACSPTWSCLITEDTGFDLGVTIAHEIGHSFGLEHDGAPGS
GCGPSGHVMASDGAAPRAGLAWSPCSRRQLLSLLSAGRARCVWDPPRPQPGSAGHPPDAQ
PGLYYSANEQCRVAFGPKAVACTFAREHLDMCQALSCHTDPLDQSSCSRLLVPLLDGTEC
GVEKWCSKGRCRSLVELTPIAAVHGRWSSWGPRSPCSRSCGGGVVTRRRQCNNPRPAFGG
RACVGADLQAEMCNTQACEKTQLEFMSQQCARTDGQPLRSSPGGASFYHWGAAVPHSQGD
ALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLSLCVSGSCRTFGCDGRMDSQQ
VWDRCQVCGGDNSTCSPRKGSFTAGRAREYVTFLTVTPNLTSVYIANHRPLFTHLAVRIG
GRYVVAGKMSISPNTTYPSLLEDGRVEYRVALTEDRLPRLEEIRIWGPLQEDADIQVYRR
YGEEYGNLTRPDITFTYFQPKPRQAWVWAAVRGPCSVSCGAGLRWVNYSCLDQARKELVE
TVQCQGSQQPPAWPEACVLEPCPPYWAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTL
PPARCRAGAQQPAVALETCNPQPCPARWEVSEPSSCTSAGGAGLALENETCVPGADGLEA
PVTEGPGSVDEKLPAPEPCVGMSCPPGWGHLDATSAGEKAPSPWGSIRTGAQAAHVWTPA
AGSCSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPGSRREVCQAVPCPARWQYKLA
ACSVSCGRGVVRRILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLEPCPPRWKVMS
LGPCSASCGLGTARRSVACVQLDQGQDVEVDEAACAALVRPEASVPCLIADCTYRWHVGT
WMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPVTVRGCWAGPCVGQGTPSLVP
HEEAAAPGRTTATPAGASLEWSQARGLLFSPAPQPRRLLPGPQENSVQSSACGRQHLEPT
GTIDMRGPGQADCAVAIGRPLGEVVTLRVLESSLNCSAGDMLLLWGRLTWRKMCRKLLDM
TFSSKTNTLVVRQRCGRPGGGVLLRYGSQLAPETFYRECDMQLFGPWGEIVSPSLSPATS
NAGGCRLFINVAPHARIAIHALATNMGAGTEGANASYILIRDTHSLRTTAFHGQQVLYWE
SESSQAEMEFSEGFLKAQASLRGQYWTLQSWVPEMQDPQSWKGKEGT
NT seq 4284 nt   +upstreamnt  +downstreamnt
atgcaccagcgtcacccccgggcaagatgccctcccctctgtgtggccggaatccttgcc
tgtggctttctcctgggctgctggggaccctcccatttccagcagagttgtcttcaggct
ttggagccacaggccgtgtcttcttacttgagccctggtgctcccttaaaaggccgccct
ccttcccctggcttccagaggcagaggcagaggcagaggcgggctgcaggcggcatccta
cacctggagctgctggtggccgtgggccccgatgtcttccaggctcaccaggaggacaca
gagcgctatgtgctcaccaacctcaacatcggggcagaactgcttcgggacccgtccctg
ggggctcagtttcgggtgcacctggtgaagatggtcattctgacagagcctgagggtgct
ccaaatatcacagccaacctcacctcgtccctgctgagcgtctgtgggtggagccagacc
atcaaccctgaggacgacacggatcctggccatgctgacctggtcctctatatcactagg
tttgacctggagttgcctgatggtaaccggcaggtgcggggcgtcacccagctgggcggt
gcctgctccccaacctggagctgcctcattaccgaggacactggcttcgacctgggagtc
accattgcccatgagattgggcacagcttcggcctggagcacgacggcgcgcccggcagc
ggctgcggccccagcggacacgtgatggcttcggacggcgccgcgccccgcgccggcctc
gcctggtccccctgcagccgccggcagctgctgagcctgctcagcgcaggacgggcgcgc
tgcgtgtgggacccgccgcggcctcaacccgggtccgcggggcacccgccggatgcgcag
cctggcctctactacagcgccaacgagcagtgccgcgtggccttcggccccaaggctgtc
gcctgcaccttcgccagggagcacctggatatgtgccaggccctctcctgccacacagac
ccgctggaccaaagcagctgcagccgcctcctcgttcctctcctggatgggacagaatgt
ggcgtggagaagtggtgctccaagggtcgctgccgctccctggtggagctgacccccata
gcagcagtgcatgggcgctggtctagctggggtccccgaagtccttgctcccgctcctgc
ggaggaggtgtggtcaccaggaggcggcagtgcaacaaccccagacctgcctttgggggg
cgtgcatgtgttggtgctgacctccaggccgagatgtgcaacactcaggcctgcgagaag
acccagctggagttcatgtcgcaacagtgcgccaggaccgacggccagccgctgcgctcc
tcccctggcggcgcctccttctaccactggggtgctgctgtaccacacagccaaggggat
gctctgtgcagacacatgtgccgggccattggcgagagcttcatcatgaagcgtggagac
agcttcctcgatgggacccggtgtatgccaagtggcccccgggaggacgggaccctgagc
ctgtgtgtgtcgggcagctgcaggacatttggctgtgatggtaggatggactcccagcag
gtatgggacaggtgccaggtgtgtggtggggacaacagcacgtgcagcccacggaagggc
tctttcacagctggcagagcgagagaatatgtcacgtttctgacagttacccccaacctg
accagtgtctacattgccaaccacaggcctctcttcacacacttggcggtgaggatcgga
gggcgctatgtcgtggctgggaagatgagcatctcccctaacaccacctacccctccctc
ctggaggatggtcgtgtcgagtacagagtggccctcaccgaggaccggctgccccgcctg
gaggagatccgcatctggggacccctccaggaagatgctgacatccaggtttacaggcgg
tatggcgaggagtatggcaacctcacccgcccagacatcaccttcacctacttccagcct
aagccacggcaggcctgggtgtgggccgctgtgcgtgggccctgctcggtgagctgtggg
gcagggctgcgctgggtaaactacagctgcctggaccaggccaggaaggagttggtggag
actgtccagtgccaagggagccagcagccaccagcgtggccagaggcctgcgtgctcgaa
ccctgccctccctactgggcggtgggagacttcggcccatgcagcgcctcctgtgggggt
ggcctgcgggagcggccagtgcgctgcgtggaggcccagggcagcctcctgaagacattg
cccccagcccggtgcagagcaggggcccagcagccagctgtggcgctggaaacctgcaac
ccccagccctgccctgccaggtgggaggtgtcagagcccagctcatgcacatcagctggt
ggagcaggcctggccttggagaacgagacctgtgtgccaggggcagatggcctggaggct
ccagtgactgaggggcctggctccgtagatgagaagctgcctgcccctgagccctgtgtc
gggatgtcatgtcctccaggctggggccatctggatgccacctctgcaggggagaaggct
ccctccccatggggcagcatcaggacgggggctcaagctgcacacgtgtggacccctgcg
gcagggtcgtgctccgtctcctgcgggcgaggtctgatggagctgcgtttcctgtgcatg
gactctgccctcagggtgcctgtccaggaagagctgtgtggcctggcaagcaagcctggg
agccggcgggaggtctgccaggctgtcccgtgccctgctcggtggcagtacaagctggcg
gcctgcagcgtgagctgtgggagaggggtcgtgcggaggatcctgtattgtgcccgggcc
catggggaggacgatggtgaggagatcctgttggacacccagtgccaggggctgcctcgc
ccggaaccccaggaggcctgcagcctggagccctgcccacctaggtggaaagtcatgtcc
cttggcccatgttcggccagctgtggccttggcactgctagacgctcggtggcctgtgtg
cagctcgaccaaggccaggacgtggaggtggacgaggcggcctgtgcggcgctggtgcgg
cccgaggccagtgtcccctgtctcattgccgactgcacctaccgctggcatgttggcacc
tggatggagtgctctgtttcctgtggggatggcatccagcgccggcgtgacacctgcctc
ggaccccaggcccaggcgcctgtgccagctgatttctgccagcacttgcccaagccggtg
actgtgcgtggctgctgggctgggccctgtgtgggacagggtacgcccagcctggtgccc
cacgaagaagccgctgctccaggacggaccacagccacccctgctggtgcctccctggag
tggtcccaggcccggggcctgctcttctccccggctccccagcctcggcggctcctgccc
gggccccaggaaaactcagtgcagtccagtgcctgtggcaggcagcaccttgagccaaca
ggaaccattgacatgcgaggcccagggcaggcagactgtgcagtggccattgggcggccc
ctcggggaggtggtgaccctccgcgtccttgagagttctctcaactgcagtgcgggggac
atgttgctgctttggggccggctcacctggaggaagatgtgcaggaagctgttggacatg
actttcagctccaagaccaacacgctggtggtgaggcagcgctgcgggcggccaggaggt
ggggtgctgctgcggtatgggagccagcttgctcctgaaaccttctacagagaatgtgac
atgcagctctttgggccctggggtgaaatcgtgagcccctcgctgagtccagccacgagt
aatgcagggggctgccggctcttcattaatgtggctccgcacgcacggattgccatccat
gccctggccaccaacatgggcgctgggaccgagggagccaatgccagctacatcttgatc
cgggacacccacagcttgaggaccacagcgttccatgggcagcaggtgctctactgggag
tcagagagcagccaggctgagatggagttcagcgagggcttcctgaaggctcaggccagc
ctgcggggccagtactggaccctccaatcatgggtaccggagatgcaggaccctcagtcc
tggaagggaaaggaaggaacctga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (48)   
   KEGG ORTHOLOGY (1)   
   RefGene (40)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (12)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (10)   
DNA sequence (53)   
   RefSeq(nuc) (13)   
   GenBank (20)   
   EMBL (20)   
Protein domain (13)   
   Pfam (13)   
All databases (134)   

Download RDF
DBGET integrated database retrieval system