KEGG T01001: 1128

Aclatonium (DG01291):

Aclidinium bromide:

Alvameline maleate:

D02876

Anisotropine methylbromide:

Atropine (DG00052):

Atropine oxide (DG01243):

Batefenterol (DG01627):

Benapryzine hydrochloride:

Benzatropine (DG00859):

Benzetimide (DG01301):

Benzilone:

Bethanechol (DG00991):

Bevonium:

Biperiden (DG00852):

Blarcamesine (DG03048):

Bornaprine:

Butropium bromide:

Butylscopolamine:

Carbachol:

Carpronium (DG01289):

Chlorpromazine (DG00867):

Choline alfoscerate:

Cimetropium bromide:

Clidinium bromide:

Cyclopentolate (DG01141):

Darotropium bromide:

Dexetimide (DG00856):

Dicycloverine (DG00032):

D00717 D07820

Diethazine (DG01921):

Difemerine:

Dihexyverine (DG00033):

Dimetindene (DG00386):

D07853

Diphenidol (DG02880):

Diphenylpiperidinomethyldioxolan iodide:

Diponium bromide:

Elantrine:

Elucaine:

Esoxybutynin chloride:

D04057

Etomidoline:

D01359

Etybenzatropine:

D04087

Eucatropine hydrochloride:

D04116

Fenpiverinium:

D07070

Fentonium:

D07951

Fesoterodine (DG00483):

D07226 D08923

Flutropium bromide:

D02417

Gallamine:

D02292

Glycopyrronium (DG02467):

D10939

Heteronium bromide:

Homatropine (DG01142):

Hyoscyamine (DG00053):

Ipratropium bromide:

Mazaticol (DG00857):

Mebeverine (DG00030):

Mepenzolate (DG00040):

Methacholine (DG01290):

Methantheline (DG00036):

Methscopolamine bromide:

Methylatropine (DG01242):

Methylbenactyzium bromide:

Methylscopolamine:

Metixene (DG00853):

Metoquizine:

Milameline hydrochloride:

Otilonium bromide:

Oxapium iodide:

Oxitropium bromide:

Oxybutynin (DG00478):

Oxyphencyclimine (DG00029):

D01006 D08325

Parapenzolate bromide:

Pentapiperium methylsulfate:

Penthienate:

Phencarbamide:

Phenglutarimide:

Pilocarpine (DG00992):

D00525 D02200 D05478 D08376

Pipenzolate:

D07084

Piperidolate (DG00034):

Pipethanate (DG01255):

Pipethanate ethobromide:

Pirenzepine (DG00026):

Piroheptine (DG01272):

Poldine:

Pridinol (DG00774):

Prifinium bromide:

Procyclidine (DG00854):

Profenamine (DG00855):

Propantheline (DG00035):

Propenzolate hydrochloride:

Propiverine (DG00479):

Rapacuronium bromide:

D05703

Revefenacin:

D10978

Rocuronium bromide:

D00765

Scopolamine (DG00065):

Sofpironium bromide:

Tazomeline citrate:

Tematropium methylsulfate:

Tiemonium (DG01254):

Tiemonium iodide:

Timepidium bromide (DG00041):

Tofenacin hydrochloride:

Toquizine:

Triampyzine sulfate:

Tridihexethyl (DG00037):

D00723

Trihexyphenidyl (DG00851):

Tropatepine (DG00858):

Tropicamide:

Trospium:

D01103

Umeclidinium (DG01253):

Umeclidinium bromide:

Valethamate:

Brite

KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    1129 (CHRM2)
   04024 cAMP signaling pathway
    1129 (CHRM2)
   04151 PI3K-Akt signaling pathway
    1129 (CHRM2)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    1129 (CHRM2)
09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    1129 (CHRM2)
09150 Organismal Systems
  09156 Nervous system
   04725 Cholinergic synapse
    1129 (CHRM2)
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    1129 (CHRM2)
G protein-coupled receptors [BR:hsa04030]
Rhodopsin family
  Biogenic amine
   Acetylcholine (muscarinic)
    1129 (CHRM2)

SSDB

Motif

Pfam:

7tm_1 7TM_GPCR_Srx 7tm_4

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

Vega:

Pharos:

P08172(Tclin)

UniProt:

P08172 A4D1Q0 Q6SL56 Q86SJ1

Structure

PDB:

5ZKC 5YC8 5ZK3 5ZKB 5ZK8 4MQS 6OIK 4MQT

Position

7q33

AA seq 466 aa
MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI
VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE
ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI
VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR

NT seq 1401 nt +upstreamnt +downstreamnt
atgaataactcaacaaactcctctaacaatagcctggctcttacaagtccttataagaca
tttgaagtggtgtttattgtcctggtggctggatccctcagtttggtgaccattatcggg
aacatcctagtcatggtttccattaaagtcaaccgccacctccagaccgtcaacaattac
tttttattcagcttggcctgtgctgaccttatcataggtgttttctccatgaacttgtac
accctctacactgtgattggttactggcctttgggacctgtggtgtgtgacctttggcta
gccctggactatgtggtcagcaatgcctcagttatgaatctgctcatcatcagctttgac
aggtacttctgtgtcacaaaacctctgacctacccagtcaagcggaccacaaaaatggca
ggtatgatgattgcagctgcctgggtcctctctttcatcctctgggctccagccattctc
ttctggcagttcattgtaggggtgagaactgtggaggatggggagtgctacattcagttt
ttttccaatgctgctgtcacctttggtacggctattgcagccttctatttgccagtgatc
atcatgactgtgctatattggcacatatcccgagccagcaagagcaggataaagaaggac
aagaaggagcctgttgccaaccaagaccccgtttctccaagtctggtacaaggaaggata
gtgaagccaaacaataacaacatgcccagcagtgacgatggcctggagcacaacaaaatc
cagaatggcaaagcccccagggatcctgtgactgaaaactgtgttcagggagaggagaag
gagagctccaatgactccacctcagtcagtgctgttgcctctaatatgagagatgatgaa
ataacccaggatgaaaacacagtttccacttccctgggccattccaaagatgagaactct
aagcaaacatgcatcagaattggcaccaagaccccaaaaagtgactcatgtaccccaact
aataccaccgtggaggtagtggggtcttcaggtcagaatggagatgaaaagcagaatatt
gtagcccgcaagattgtgaagatgactaagcagcctgcaaaaaagaagcctcctccttcc
cgggaaaagaaagtcaccaggacaatcttggctattctgttggctttcatcatcacttgg
gccccatacaatgtcatggtgctcattaacaccttttgtgcaccttgcatccccaacact
gtgtggacaattggttactggctttgttacatcaacagcactatcaaccctgcctgctat
gcactttgcaatgccaccttcaagaagacctttaaacaccttctcatgtgtcattataag
aacataggcgctacaaggtaa

Homo sapiens (human): 1131

Entry

1131 CDS T01001

Gene name

CHRM3, EGBRS, HM3, PBS

Definition

(RefSeq) cholinergic receptor muscarinic 3

K04131

muscarinic acetylcholine receptor M3

Organism

hsa Homo sapiens (human)

Pathway

hsa04020

Calcium signaling pathway

hsa04080

Neuroactive ligand-receptor interaction

hsa04725

Cholinergic synapse

hsa04742

Taste transduction

hsa04810

Regulation of actin cytoskeleton

hsa04911

Insulin secretion

hsa04970

Salivary secretion

hsa04971

Gastric acid secretion

hsa04972

Pancreatic secretion

Disease

H02129

Prune belly syndrome

Drug target

Acetylcholine (DG01133):

Aclatonium (DG01291):

Aclidinium bromide:

Alvameline maleate:

D02876

Anisotropine methylbromide:

Atropine (DG00052):

Atropine oxide (DG01243):

Batefenterol (DG01627):

Benapryzine hydrochloride:

Benzatropine (DG00859):

Benzetimide (DG01301):

Benzilone:

Bethanechol (DG00991):

Bevonium:

Biperiden (DG00852):

Blarcamesine (DG03048):

Bornaprine:

Butropium bromide:

Butylscopolamine:

Carbachol:

Carpronium (DG01289):

Cevimeline (DG00993):

D00661 D07667

Chlorpromazine (DG00867):

Choline alfoscerate:

Cimetropium bromide:

Clidinium bromide:

Cyclopentolate (DG01141):

Darifenacin (DG00482):

D01699 D03654

Darotropium bromide:

Desfesoterodine:

D10853

Dexetimide (DG00856):

Dexpanthenol:

D00193

Dicycloverine (DG00032):

D00717 D07820

Diethazine (DG01921):

Difemerine:

Dihexyverine (DG00033):

Diphemanil:

D06878

Diphenidol (DG02880):

Diphenylpiperidinomethyldioxolan iodide:

Diponium bromide:

Elantrine:

Elucaine:

Esoxybutynin chloride:

D04057

Etomidoline:

D01359

Etybenzatropine:

D04087

Eucatropine hydrochloride:

D04116

Fenpiverinium:

D07070

Fentonium:

D07951

Fesoterodine (DG00483):

D07226 D08923

Flutropium bromide:

D02417

Glycopyrronium:

D00540

Glycopyrronium (DG02467):

D10938 D10939

Heteronium bromide:

Hexocyclium (DG00039):

D01003

Homatropine (DG01142):

Hyoscyamine (DG00053):

Imidafenacin:

D06273

Ipratropium bromide:

Isopropamide (DG00038):

D01005

Mazaticol (DG00857):

Mebeverine (DG00030):

Mepenzolate (DG00040):

Methacholine (DG01290):

Methantheline (DG00036):

Methscopolamine bromide:

Methylatropine (DG01242):

Methylbenactyzium bromide:

Methylscopolamine:

Metixene (DG00853):

Metoquizine:

Milameline hydrochloride:

Otilonium bromide:

Oxapium iodide:

Oxitropium bromide:

Oxybutynin (DG00478):

Oxyphencyclimine (DG00029):

D01006 D08325

Parapenzolate bromide:

Pentapiperium methylsulfate:

Penthienate:

Phencarbamide:

Phenglutarimide:

Pilocarpine (DG00992):

D00525 D02200 D05478 D08376

Pipenzolate:

D07084

Piperidolate (DG00034):

Pipethanate (DG01255):

Pipethanate ethobromide:

Pirenzepine (DG00026):

Piroheptine (DG01272):

Poldine:

Pridinol (DG00774):

Prifinium bromide:

Procyclidine (DG00854):

Profenamine (DG00855):

Propantheline (DG00035):

Propenzolate hydrochloride:

Propiverine (DG00479):

Rapacuronium bromide:

Revefenacin:

Rociverine:

Rocuronium bromide:

Scopolamine (DG00065):

Sofpironium bromide:

Solifenacin (DG00481):

D01269 D08522

Tazomeline citrate:

Tematropium methylsulfate:

Tiemonium (DG01254):

Tiemonium iodide:

Timepidium bromide (DG00041):

Tiotropium bromide:

D01929

Tiquizium bromide:

D01875

Tofenacin hydrochloride:

Tolterodine (DG00480):

D00646 D01148

Toquizine:

Triampyzine sulfate:

Tridihexethyl (DG00037):

D00723

Trihexyphenidyl (DG00851):

Tropatepine (DG00858):

Tropicamide:

Trospium:

D01103

Umeclidinium (DG01253):

Umeclidinium bromide:

Valethamate:

7tm_1 7TM_GPCR_Srsx 7TM_GPCR_Srx 7tm_4 7TM_GPCR_Srbc

Brite

KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    1131 (CHRM3)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    1131 (CHRM3)
09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    1131 (CHRM3)
09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    1131 (CHRM3)
  09154 Digestive system
   04970 Salivary secretion
    1131 (CHRM3)
   04971 Gastric acid secretion
    1131 (CHRM3)
   04972 Pancreatic secretion
    1131 (CHRM3)
  09156 Nervous system
   04725 Cholinergic synapse
    1131 (CHRM3)
  09157 Sensory system
   04742 Taste transduction
    1131 (CHRM3)
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    1131 (CHRM3)
G protein-coupled receptors [BR:hsa04030]
Rhodopsin family
  Biogenic amine
   Acetylcholine (muscarinic)
    1131 (CHRM3)

SSDB

Motif

Pfam:

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

Vega:

Pharos:

P20309(Tclin)

UniProt:

P20309 A0A024R3S2

Position

1q43

AA seq 590 aa
MTLHNNSTTSPLFPNISSSWIHSPSDAGLPPGTVTHFGSYNVSRAAGNFSSPDGTTDDPL
GGHTVWQVVFIAFLTGILALVTIIGNILVIVSFKVNKQLKTVNNYFLLSLACADLIIGVI
SMNLFTTYIIMNRWALGNLACDLWLAIDYVASNASVMNLLVISFDRYFSITRPLTYRAKR
TTKRAGVMIGLAWVISFVLWAPAILFWQYFVGKRTVPPGECFIQFLSEPTITFGTAIAAF
YMPVTIMTILYWRIYKETEKRTKELAGLQASGTEAETENFVHPTGSSRSCSSYELQQQSM
KRSNRRKYGRCHFWFTTKSWKPSSEQMDQDHSSSDSWNNNDAAASLENSASSDEEDIGSE
TRAIYSIVLKLPGHSTILNSTKLPSSDNLQVPEEELGMVDLERKADKLQAQKSVDDGGSF
PKSFSKLPIQLESAVDTAKTSDVNSSVGKSTATLPLSFKEATLAKRFALKTRSQITKRKR
MSLVKEKKAAQTLSAILLAFIITWTPYNIMVLVNTFCDSCIPKTFWNLGYWLCYINSTVN
PVCYALCNKTFRTTFKMLLLCQCDKKKRRKQQYQQRQSVIFHKRAPEQAL

NT seq 1773 nt +upstreamnt +downstreamnt
atgaccttgcacaataacagtacaacctcgcctttgtttccaaacatcagctcctcctgg
atacacagcccctccgatgcagggctgcccccgggaaccgtcactcatttcggcagctac
aatgtttctcgagcagctggcaatttctcctctccagacggtaccaccgatgaccctctg
ggaggtcataccgtctggcaagtggtcttcatcgctttcttaacgggcatcctggccttg
gtgaccatcatcggcaacatcctggtaattgtgtcatttaaggtcaacaagcagctgaag
acggtcaacaactacttcctcttaagcctggcctgtgccgatctgattatcggggtcatt
tcaatgaatctgtttacgacctacatcatcatgaatcgatgggccttagggaacttggcc
tgtgacctctggcttgccattgactacgtagccagcaatgcctctgttatgaatcttctg
gtcatcagctttgacagatacttttccatcacgaggccgctcacgtaccgagccaaacga
acaacaaagagagccggtgtgatgatcggtctggcttgggtcatctcctttgtcctttgg
gctcctgccatcttgttctggcaatactttgttggaaagagaactgtgcctccgggagag
tgcttcattcagttcctcagtgagcccaccattacttttggcacagccatcgctgctttt
tatatgcctgtcaccattatgactattttatactggaggatctataaggaaactgaaaag
cgtaccaaagagcttgctggcctgcaagcctctgggacagaggcagagacagaaaacttt
gtccaccccacgggcagttctcgaagctgcagcagttacgaacttcaacagcaaagcatg
aaacgctccaacaggaggaagtatggccgctgccacttctggttcacaaccaagagctgg
aaacccagctccgagcagatggaccaagaccacagcagcagtgacagttggaacaacaat
gatgctgctgcctccctggagaactccgcctcctccgacgaggaggacattggctccgag
acgagagccatctactccatcgtgctcaagcttccgggtcacagcaccatcctcaactcc
accaagttaccctcatcggacaacctgcaggtgcctgaggaggagctggggatggtggac
ttggagaggaaagccgacaagctgcaggcccagaagagcgtggacgatggaggcagtttt
ccaaaaagcttctccaagcttcccatccagctagagtcagccgtggacacagctaagact
tctgacgtcaactcctcagtgggtaagagcacggccactctacctctgtccttcaaggaa
gccactctggccaagaggtttgctctgaagaccagaagtcagatcactaagcggaaaagg
atgtccctggtcaaggagaagaaagcggcccagaccctcagtgcgatcttgcttgccttc
atcatcacttggaccccatacaacatcatggttctggtgaacaccttttgtgacagctgc
atacccaaaaccttttggaatctgggctactggctgtgctacatcaacagcaccgtgaac
cccgtgtgctatgctctgtgcaacaaaacattcagaaccactttcaagatgctgctgctg
tgccagtgtgacaaaaaaaagaggcgcaagcagcagtaccagcagagacagtcggtcatt
tttcacaagcgcgcacccgagcaggccttgtag

Homo sapiens (human): 1132

Entry

1132 CDS T01001

Gene name

CHRM4, HM4, M4R

Definition

(RefSeq) cholinergic receptor muscarinic 4

K04132

muscarinic acetylcholine receptor M4

Organism

hsa Homo sapiens (human)

Pathway

hsa04080

Neuroactive ligand-receptor interaction

hsa04725

Cholinergic synapse

hsa04810

Regulation of actin cytoskeleton

Drug target

Acetylcholine (DG01133):

Aclatonium (DG01291):

Aclidinium bromide:

Anisotropine methylbromide:

Atropine (DG00052):

Atropine oxide (DG01243):

Batefenterol (DG01627):

Benapryzine hydrochloride:

Benzatropine (DG00859):

Benzetimide (DG01301):

Benzilone:

Bethanechol (DG00991):

Bevonium:

Biperiden (DG00852):

Blarcamesine (DG03048):

Bornaprine:

Butropium bromide:

Butylscopolamine:

Carbachol:

Carpronium (DG01289):

Chlorpromazine (DG00867):

Choline alfoscerate:

Cimetropium bromide:

Clidinium bromide:

Cyclopentolate (DG01141):

Darotropium bromide:

Dexetimide (DG00856):

Diethazine (DG01921):

Difemerine:

Dihexyverine (DG00033):

Diphenidol (DG02880):

Diphenylpiperidinomethyldioxolan iodide:

Diponium bromide:

Elantrine:

Elucaine:

Etomidoline:

Etybenzatropine:

Eucatropine hydrochloride:

Fenpiverinium:

Fentonium:

Flutropium bromide:

Glycopyrronium (DG02467):

D10939

Heteronium bromide:

Homatropine (DG01142):

Hyoscyamine (DG00053):

Ipratropium bromide:

Mazaticol (DG00857):

Mebeverine (DG00030):

Mepenzolate (DG00040):

Methacholine (DG01290):

Methantheline (DG00036):

Methscopolamine bromide:

Methylatropine (DG01242):

Methylbenactyzium bromide:

Methylscopolamine:

Metixene (DG00853):

Metoquizine:

Milameline hydrochloride:

Otilonium bromide:

Oxapium iodide:

Oxitropium bromide:

Oxybutynin (DG00478):

Parapenzolate bromide:

Pentapiperium methylsulfate:

Penthienate:

Phencarbamide:

Phenglutarimide:

Pipenzolate:

Piperidolate (DG00034):

Pipethanate (DG01255):

Pipethanate ethobromide:

Pirenzepine (DG00026):

Piroheptine (DG01272):

Poldine:

Pridinol (DG00774):

Prifinium bromide:

Procyclidine (DG00854):

Profenamine (DG00855):

Propantheline (DG00035):

Propenzolate hydrochloride:

Propiverine (DG00479):

Rapacuronium bromide:

D05703

Revefenacin:

D10978

Rocuronium bromide:

D00765

Scopolamine (DG00065):

Sofpironium bromide:

Tazomeline citrate:

Tematropium methylsulfate:

Tiemonium (DG01254):

Tiemonium iodide:

Timepidium bromide (DG00041):

Tofenacin hydrochloride:

Toquizine:

Triampyzine sulfate:

Trihexyphenidyl (DG00851):

Tropatepine (DG00858):

Tropicamide:

Umeclidinium (DG01253):

Umeclidinium bromide:

Valethamate:

7tm_1 7TM_GPCR_Srx 7TM_GPCR_Srsx 7tm_4

Xanomeline (DG01300):

D06330 D06331

Brite

KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    1132 (CHRM4)
09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    1132 (CHRM4)
09150 Organismal Systems
  09156 Nervous system
   04725 Cholinergic synapse
    1132 (CHRM4)
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    1132 (CHRM4)
G protein-coupled receptors [BR:hsa04030]
Rhodopsin family
  Biogenic amine
   Acetylcholine (muscarinic)
    1132 (CHRM4)

SSDB

Motif

Pfam:

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

Vega:

Pharos:

P08173(Tclin)

UniProt:

P08173

Position

11p11.2

AA seq 479 aa
MANFTPVNGSSGNQSVRLVTSSSHNRYETVEMVFIATVTGSLSLVTVVGNILVMLSIKVN
RQLQTVNNYFLFSLACADLIIGAFSMNLYTVYIIKGYWPLGAVVCDLWLALDYVVSNASV
MNLLIISFDRYFCVTKPLTYPARRTTKMAGLMIAAAWVLSFVLWAPAILFWQFVVGKRTV
PDNQCFIQFLSNPAVTFGTAIAAFYLPVVIMTVLYIHISLASRSRVHKHRPEGPKEKKAK
TLAFLKSPLMKQSVKKPPPGEAAREELRNGKLEEAPPPALPPPPRPVADKDTSNESSSGS
ATQNTKERPATELSTTEATTPAMPAPPLQPRALNPASRWSKIQIVTKQTGNECVTAIEIV
PATPAGMRPAANVARKFASIARNQVRKKRQMAARERKVTRTIFAILLAFILTWTPYNVMV
LVNTFCQSCIPDTVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLLLCQYRNIGTAR

NT seq 1440 nt +upstreamnt +downstreamnt
atggccaacttcacacctgtcaatggcagctcgggcaatcagtccgtgcgcctggtcacg
tcatcatcccacaatcgctatgagacggtggaaatggtcttcattgccacagtgacaggc
tccctgagcctggtgactgtcgtgggcaacatcctggtgatgctgtccatcaaggtcaac
aggcagctgcagacagtcaacaactacttcctcttcagcctggcgtgtgctgatctcatc
ataggcgccttctccatgaacctctacaccgtgtacatcatcaagggctactggcccctg
ggcgccgtggtctgcgacctgtggctggccctggactacgtggtgagcaacgcctccgtc
atgaaccttctcatcatcagctttgaccgctacttctgcgtcaccaagcctctcacctac
cctgcccggcgcaccaccaagatggcaggcctcatgattgctgctgcctgggtactgtcc
ttcgtgctctgggcgcctgccatcttgttctggcagtttgtggtgggtaagcggacggtg
cccgacaaccagtgcttcatccagttcctgtccaacccagcagtgacctttggcacagcc
attgctgccttctacctgcctgtggtcatcatgacggtgctgtacatccacatctccctg
gccagtcgcagccgagtccacaagcaccggcccgagggcccgaaggagaagaaagccaag
acgctggccttcctcaagagcccactaatgaagcagagcgtcaagaagcccccgcccggg
gaggccgcccgggaggagctgcgcaatggcaagctggaggaggcccccccgccagcgctg
ccaccgccaccgcgccccgtggctgataaggacacttccaatgagtccagctcaggcagt
gccacccagaacaccaaggaacgcccagccacagagctgtccaccacagaggccaccacg
cccgccatgcccgcccctcccctgcagccgcgggccctcaacccagcctccagatggtcc
aagatccagattgtgacgaagcagacaggcaatgagtgtgtgacagccattgagattgtg
cctgccacgccggctggcatgcgccctgcggccaacgtggcccgcaagttcgccagcatc
gctcgcaaccaggtgcgcaagaagcggcagatggcggcccgggagcgcaaagtgacacga
acgatctttgccattctgctagccttcatcctcacctggacgccctacaacgtcatggtc
ctggtgaacaccttctgccagagctgcatccctgacacggtgtggtccattggctactgg
ctctgctacgtcaacagcaccatcaaccctgcctgctatgctctgtgcaacgccaccttt
aaaaagaccttccggcacctgctgctgtgccagtatcggaacatcggcactgccaggtag

Homo sapiens (human): 1133

Entry

1133 CDS T01001

Gene name

CHRM5, HM5

Definition

(RefSeq) cholinergic receptor muscarinic 5

K04133

muscarinic acetylcholine receptor M5

Organism

hsa Homo sapiens (human)

Pathway

hsa04020

Calcium signaling pathway

hsa04080

Neuroactive ligand-receptor interaction

hsa04725

Cholinergic synapse

hsa04810

Regulation of actin cytoskeleton

Drug target

Acetylcholine (DG01133):

Aclatonium (DG01291):

Aclidinium bromide:

Anisotropine methylbromide:

Atropine (DG00052):

Atropine oxide (DG01243):

Batefenterol (DG01627):

Benapryzine hydrochloride:

Benzatropine (DG00859):

Benzetimide (DG01301):

Benzilone:

Bethanechol (DG00991):

Bevonium:

Biperiden (DG00852):

Blarcamesine (DG03048):

Bornaprine:

Butropium bromide:

Butylscopolamine:

Carbachol:

Carpronium (DG01289):

Chlorpromazine (DG00867):

Choline alfoscerate:

Cimetropium bromide:

Clidinium bromide:

Cyclopentolate (DG01141):

Darotropium bromide:

Dexetimide (DG00856):

Diethazine (DG01921):

Difemerine:

Dihexyverine (DG00033):

Diphenidol (DG02880):

Diphenylpiperidinomethyldioxolan iodide:

Diponium bromide:

Elantrine:

Elucaine:

Etomidoline:

Etybenzatropine:

Eucatropine hydrochloride:

Fenpiverinium:

Fentonium:

Flutropium bromide:

Glycopyrronium (DG02467):

D10939

Heteronium bromide:

Homatropine (DG01142):

Hyoscyamine (DG00053):

Ipratropium bromide:

Mazaticol (DG00857):

Mebeverine (DG00030):

Mepenzolate (DG00040):

Methacholine (DG01290):

Methantheline (DG00036):

Methscopolamine bromide:

Methylatropine (DG01242):

Methylbenactyzium bromide:

Methylscopolamine:

Metixene (DG00853):

Metoquizine:

Milameline hydrochloride:

Otilonium bromide:

Oxapium iodide:

Oxitropium bromide:

Oxybutynin (DG00478):

Parapenzolate bromide:

Pentapiperium methylsulfate:

Penthienate:

Phencarbamide:

Phenglutarimide:

Pipenzolate:

Piperidolate (DG00034):

Pipethanate (DG01255):

Pipethanate ethobromide:

Pirenzepine (DG00026):

Piroheptine (DG01272):

Poldine:

Pridinol (DG00774):

Prifinium bromide:

Procyclidine (DG00854):

Profenamine (DG00855):

Propantheline (DG00035):

Propenzolate hydrochloride:

Propiverine (DG00479):

Rapacuronium bromide:

D05703

Revefenacin:

D10978

Rocuronium bromide:

D00765

Scopolamine (DG00065):

Sofpironium bromide:

Tazomeline citrate:

Tematropium methylsulfate:

Tiemonium (DG01254):

Tiemonium iodide:

Timepidium bromide (DG00041):

Tofenacin hydrochloride:

Toquizine:

Triampyzine sulfate:

Trihexyphenidyl (DG00851):

Tropatepine (DG00858):

Tropicamide:

Umeclidinium (DG01253):

Umeclidinium bromide:

Valethamate: