| Entry |
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| Symbol |
CHRNA1, ACHRA, ACHRD, CHRNA, CMS1A, CMS1B, CMS2A, FCCMS, SCCMS
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| Name |
(RefSeq) cholinergic receptor nicotinic alpha 1 subunit
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| KO |
| K04803 | nicotinic acetylcholine receptor alpha-1 |
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| Organism |
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| Pathway |
| hsa03265 | Virion - Ebolavirus, Lyssavirus and Morbillivirus |
| hsa04080 | Neuroactive ligand-receptor interaction |
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| Disease |
| H00770 | Congenital myasthenic syndrome |
| H00986 | Multiple pterygium syndrome |
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| Drug target |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09120 Genetic Information Processing
09125 Information processing in viruses
03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus
1134 (CHRNA1)
09130 Environmental Information Processing
09133 Signaling molecules and interaction
04080 Neuroactive ligand-receptor interaction
1134 (CHRNA1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:hsa04040]
1134 (CHRNA1)
Ion channels [BR:hsa04040]
Ligand-gated channels
Acetylcholine (nicotinic)
1134 (CHRNA1)
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
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| Position |
2:complement(174747592..174764472)
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| AA seq |
457 aa
MEPWPLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQL
INVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNADGDF
AIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAINP
ESDQPDLSNFMESGEWVIKESRGWKHSVTYSCCPDTPYLDITYHFVMQRLPLYFIVNVII
PCLLFSFLTGLVFYLPTDSGEKMTLSISVLLSLTVFLLVIVELIPSTSSAVPLIGKYMLF
TMVFVIASIIITVIVINTHHRSPSTHVMPNWVRKVFIDTIPNIMFFSTMKRPSREKQDKK
IFTEDIDISDISGKPGPPPMGFHSPLIKHPEVKSAIEGIKYIAETMKSDQESNNAAAEWK
YVAMVMDHILLGVFMLVCIIGTLAVFAGRLIELNQQG |
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| NT seq |
1374 nt +upstreamnt +downstreamnt
atggagccctggcctctcctcctgctctttagcctttgctcagctggcctcgtcctgggc
tccgaacatgagacccgtctggtggcaaagctatttaaagactacagcagcgtggtgcgg
ccagtggaagaccaccgccaggtcgtggaggtcaccgtgggcctgcagctgatacagctc
atcaatgtggatgaagtaaatcagatcgtgacaaccaatgtgcgtctgaaacagcaatgg
gtggattacaacctaaaatggaatccagatgactatggcggtgtgaaaaaaattcacatt
ccttcagaaaagatctggcgcccagaccttgttctctataacaatgcagatggtgacttt
gctattgtcaagttcaccaaagtgctcctgcagtacactggccacatcacgtggacacct
ccagccatctttaaaagctactgtgagatcatcgtcacccactttccctttgatgaacag
aactgcagcatgaagctgggcacctggacctacgacggctctgtcgtggccatcaacccg
gaaagcgaccagccagacctgagcaacttcatggagagcggggagtgggtgatcaaggag
tcccggggctggaagcactccgtgacctattcctgctgccccgacaccccctacctggac
atcacctaccacttcgtcatgcagcgcctgcccctctacttcatcgtcaacgtcatcatc
ccctgcctgctcttctccttcttaactggcctggtattctacctgcccacagactcaggg
gagaagatgactctgagcatctctgtcttactgtctttgactgtgttccttctggtcatc
gtggagctgatcccctccacgtccagtgctgtgcccttgattggaaaatacatgctgttc
accatggtgttcgtcattgcctccatcatcatcactgtcatcgtcatcaacacacaccac
cgctcacccagcacccatgtcatgcccaactgggtgcggaaggtttttatcgacactatc
ccaaatatcatgtttttctccacaatgaaaagaccatccagagaaaagcaagacaaaaag
atttttacagaagacattgatatctctgacatttctggaaagccagggcctccacccatg
ggcttccactctcccctgatcaaacaccccgaggtgaaaagtgccatcgagggcatcaag
tacatcgcagagaccatgaagtcagaccaggagtctaacaatgcggcggcagagtggaag
tacgttgcaatggtgatggaccacatactcctcggagtcttcatgcttgtttgcatcatc
ggaaccctagccgtgtttgcaggtcgactcattgaattaaatcagcaaggatga |
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