KEGG   Homo sapiens (human): 113510
Entry
113510            CDS       T01001                                 
Symbol
HELQ, HEL308
Name
(RefSeq) helicase, POLQ like
  KO
K19178  POLQ-like helicase [EC:5.6.2.4]
Organism
hsa  Homo sapiens (human)
Network
nt06508  Interstrand crosslink repair
  Element
N01539  RAD51 -dsDNA destabilization
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:hsa03400]
    113510 (HELQ)
Enzymes [BR:hsa01000]
 5. Isomerases
  5.6  Isomerases altering macromolecular conformation
   5.6.2  Enzymes altering nucleic acid conformation
    5.6.2.4  DNA 3'-5' helicase
     113510 (HELQ)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  Other factors with a suspected DNA repair function
   Helicases
    113510 (HELQ)
SSDB
Motif
Pfam: POLQ_helical HTH_61 DEAD Helicase_C ResIII HHH_5 DUF4332 DNA_pol_lambd_f DUF3135
Other DBs
NCBI-GeneID: 113510
NCBI-ProteinID: NP_598375
OMIM: 606769
HGNC: 18536
Ensembl: ENSG00000163312
UniProt: Q8TDG4
Position
4:complement(83407346..83455883)
AA seq 1101 aa
MDECGSRIRRRVSLPKRNRPSLGCIFGAPTAAELVPGDEGKEEEEMVAENRRRKTAGVLP
VEVQPLLLSDSPECLVLGGGDTNPDLLRHMPTDRGVGDQPNDSEVDMFGDYDSFTENSFI
AQVDDLEQKYMQLPEHKKHATDFATENLCSESIKNKLSITTIGNLTELQTDKHTENQSGY
EGVTIEPGADLLYDVPSSQAIYFENLQNSSNDLGDHSMKERDWKSSSHNTVNEELPHNCI
EQPQQNDESSSKVRTSSDMNRRKSIKDHLKNAMTGNAKAQTPIFSRSKQLKDTLLSEEIN
VAKKTVESSSNDLGPFYSLPSKVRDLYAQFKGIEKLYEWQHTCLTLNSVQERKNLIYSLP
TSGGKTLVAEILMLQELLCCRKDVLMILPYVAIVQEKISGLSSFGIELGFFVEEYAGSKG
RFPPTKRREKKSLYIATIEKGHSLVNSLIETGRIDSLGLVVVDELHMIGEGSRGATLEMT
LAKILYTSKTTQIIGMSATLNNVEDLQKFLQAEYYTSQFRPVELKEYLKINDTIYEVDSK
AENGMTFSRLLNYKYSDTLKKMDPDHLVALVTEVIPNYSCLVFCPSKKNCENVAEMICKF
LSKEYLKHKEKEKCEVIKNLKNIGNGNLCPVLKRTIPFGVAYHHSGLTSDERKLLEEAYS
TGVLCLFTCTSTLAAGVNLPARRVILRAPYVAKEFLKRNQYKQMIGRAGRAGIDTIGESI
LILQEKDKQQVLELITKPLENCYSHLVQEFTKGIQTLFLSLIGLKIATNLDDIYHFMNGT
FFGVQQKVLLKEKSLWEITVESLRYLTEKGLLQKDTIYKSEEEVQYNFHITKLGRASFKG
TIDLAYCDILYRDLKKGLEGLVLESLLHLIYLTTPYDLVSQCNPDWMIYFRQFSQLSPAE
QNVAAILGVSESFIGKKASGQAIGKKVDKNVVNRLYLSFVLYTLLKETNIWTVSEKFNMP
RGYIQNLLTGTASFSSCVLHFCEELEEFWVYRALLVELTKKLTYCVKAELIPLMEVTGVL
EGRAKQLYSAGYKSLMHLANANPEVLVRTIDHLSRRQAKQIVSSAKMLLHEKAEALQEEV
EELLRLPSDFPGAVASSTDKA
NT seq 3306 nt   +upstreamnt  +downstreamnt
atggatgaatgtggttcccgcatccgccggcgggtgtctctccccaaaaggaaccgtcca
agcttggggtgtatttttggcgctcccaccgcggccgagctcgtgcccggagatgagggg
aaagaggaggaggaaatggtggctgagaacaggaggcggaaaaccgcgggcgtactgccg
gttgaggtacagccccttctactctcagattccccggaatgtctcgtccttggaggtggt
gatacaaacccggacctcctacgtcacatgcccactgacagaggggtgggagaccagcct
aatgacagtgaagtggacatgtttggtgactatgatagctttactgaaaactcctttata
gctcaagttgacgacctggaacaaaaatatatgcaactccctgaacataagaaacatgct
acagactttgccactgaaaatctttgctcggaaagtatcaaaaacaaactcagcattact
accataggcaaccttactgaattacaaactgataagcacacagagaaccagagtggatat
gaaggtgtcactattgaacctggagctgatcttttgtatgatgtaccttcctcacaggct
atatactttgaaaatttgcagaactcttcaaatgatttgggtgatcattctatgaaagaa
agggattggaagtcatcctctcacaacactgtgaatgaggaactgccccataattgcata
gagcaaccccagcaaaatgatgagtcctcttccaaagtcagaactagttcagatatgaac
aggagaaaaagtattaaagatcatctaaaaaatgccatgactggaaatgcgaaggcccag
acaccaatattttctagaagtaaacagctcaaagacactctcctatctgaggaaattaat
gttgctaagaaaacagttgagtcatcatcaaatgaccttggtcctttttattcattaccc
agcaaagtgagagacctttatgcccaattcaagggaattgaaaaattatatgaatggcaa
catacttgtttaacattgaattctgtgcaagaaagaaaaaatttaatatattccttgcca
acaagtggtggaaaaaccctcgtggctgagattttaatgctgcaagaactgctttgctgt
cggaaagatgttttaatgattcttccatatgtggcaattgtccaagaaaagatttcaggt
ttgtcaagttttggtatagaactcggtttctttgttgaagaatatgctggaagcaaagga
agatttcctccaactaaaagaagggaaaagaaatcactctatattgccactattgaaaaa
ggacatagcttggtgaactccttgattgaaactggaagaattgacagtctgggtctggtt
gttgtagacgagttgcacatgattggtgaaggaagccgtggagctacactggaaatgacc
ctagcaaaaatcctctacactagcaaaacgactcaaattattggtatgagtgcaacatta
aacaatgttgaagacctacaaaagtttcttcaagcagaatattataccagtcaatttaga
ccagttgagttaaaagaatatctgaaaataaatgatacaatatatgaagttgacagcaaa
gctgagaatggcatgactttttcacgtcttcttaattataagtattctgataccctaaaa
aagatggatcctgatcacttggtagcattggtgacagaagttattcccaattattcctgc
ttagttttttgtcctagtaagaagaactgtgaaaatgtagcagaaatgatatgcaaattt
ttaagcaaggaatatctgaaacataaggagaaagaaaaatgtgaggtgattaagaacttg
aagaatattggcaatggcaacctgtgtcctgttttaaagcgcactatcccatttggagtt
gcctatcaccacagtggcttaacaagtgatgaaaggaaactcttggaggaggcctactcc
acaggagtgctctgtctttttacctgcacatctaccctagcggcaggtgtcaacctacca
gctcgaagagttattttaagagctccctatgttgctaaggaatttttaaagaggaatcaa
tataaacagatgattggcagagctggtcgtgctggaatagatactattggggagagtatc
ctcatattgcaagaaaaagacaaacaacaggtattggagttaataactaaaccattggaa
aactgttacagccatcttgttcaggaattcaccaagggaatccaaacattatttctctct
ttgattggtttgaagattgcaacgaatcttgatgacatctatcatttcatgaatggtaca
ttttttggtgttcagcaaaaggttttattgaaagaaaaaagtctctgggaaataactgtt
gaatcacttagatacctgacagaaaaaggactcctacaaaaagacactatttataagtct
gaagaagaggtccaatataattttcatattacaaagttgggacgtgcttcatttaaggga
actatagatttagcttattgtgacattctgtacagagacttgaagaaaggtcttgaagga
cttgtgcttgaaagccttcttcatctaatctacctaacaaccccctatgatctggtttca
cagtgtaaccctgattggatgatatacttcaggcagtttagccaactcagtccagcagaa
caaaatgtagctgccattcttggagtctctgaaagctttattgggaagaaagcatcaggc
caagccatcggaaagaaggtggacaagaacgttgtcaacaggctatatctgtcttttgtt
ctttataccttgctcaaagagaccaacatttggactgtatctgaaaaatttaatatgcct
cgaggatatatacaaaatcttctcactggaactgcctcattctcatcttgtgtgttacat
ttctgtgaggagcttgaggagttttgggtttacagagcccttttggtagaacttaccaag
aagctgacttactgtgtaaaggcagaattaatccctctcatggaagttactggagtttta
gagggtcgagcaaaacagttatacagtgcaggttacaaaagtctaatgcacttagctaat
gcaaatcctgaagtgctcgtaaggacaattgatcatttatcaagacgccaagccaagcaa
attgtttcatcagcaaagatgctgttgcatgaaaaagcagaagccctgcaagaagaggta
gaagagttactaagattgccttctgatttccctggtgctgtggcttcttccactgacaaa
gcatga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Network (2)   
   KEGG NETWORK (2)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (22)   
   KEGG ORTHOLOGY (1)   
   RefGene (16)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (8)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (6)   
DNA sequence (45)   
   RefSeq(nuc) (7)   
   GenBank (19)   
   EMBL (19)   
Protein domain (9)   
   Pfam (9)   
All databases (92)   

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