KEGG   Homo sapiens (human): 113878
Entry
113878            CDS       T01001                                 
Symbol
DTX2, RNF58
Name
(RefSeq) deltex E3 ubiquitin ligase 2
  KO
K06058  deltex [EC:2.3.2.27]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04330  Notch signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04330 Notch signaling pathway
    113878 (DTX2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:hsa04121]
    113878 (DTX2)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.27  RING-type E3 ubiquitin transferase
     113878 (DTX2)
Ubiquitin system [BR:hsa04121]
 Ubiquitin ligases (E3)
  Single Ring-finger type E3
   Other single Ring-finger type E3
    113878 (DTX2)
SSDB
Motif
Pfam: DTC WWE zf-C3HC4 zf-rbx1 zf-RING_UBOX zf-UDP zf-LITAF-like zf-ANAPC11 TTC3_DZIP3_dom zf-RING_11
Other DBs
NCBI-GeneID: 113878
NCBI-ProteinID: NP_001096064
OMIM: 613141
HGNC: 15973
Ensembl: ENSG00000091073
UniProt: Q86UW9
Structure
Position
7:76461709..76505991
AA seq 622 aa
MAMAPSPSLVQVYTSPAAVAVWEWQDGLGTWHPYSATVCSFIEQQFVQQKGQRFGLGSLA
HSIPLGQADPSLAPYIIDLPSWTQFRQDTGTMRAVRRHLFPQHSAPGRGVVWEWLSDDGS
WTAYEASVCDYLEQQVARGNQLVDLAPLGYNYTVNYTTHTQTNKTSSFCRSVRRQAGPPY
PVTTIIAPPGHTGVACSCHQCLSGSRTGPVSGRYRHSMTNLPAYPVPQHPPHRTASVFGT
HQAFAPYNKPSLSGARSAPRLNTTNAWGAAPPSLGSQPLYRSSLSHLGPQHLPPGSSTSG
AVSASLPSGPSSSPGSVPATVPMQMPKPSRVQQALAGMTSVLMSAIGLPVCLSRAPQPTS
PPASRLASKSHGSVKRLRKMSVKGATPKPEPEPEQVIKNYTEELKVPPDEDCIICMEKLS
TASGYSDVTDSKAIGSLAVGHLTKCSHAFHLLCLLAMYCNGNKDGSLQCPSCKTIYGEKT
GTQPQGKMEVLRFQMSLPGHEDCGTILIVYSIPHGIQGPEHPNPGKPFTARGFPRQCYLP
DNAQGRKVLELLKVAWKRRLIFTVGTSSTTGETDTVVWNEIHHKTEMDRNITGHGYPDPN
YLQNVLAELAAQGVTEDCLEQQ
NT seq 1869 nt   +upstreamnt  +downstreamnt
atggccatggccccaagcccttccctggtgcaggtgtacaccagccccgcggctgtggcc
gtgtgggaatggcaggacgggctgggcacctggcacccctacagtgccaccgtctgcagc
ttcatcgagcagcagtttgtccagcagaagggccaacgttttgggcttgggagcctggcc
cacagcatccccttgggccaggcagacccctcgctggccccttacattattgacctcccc
agctggacccagttccgccaggacaccggcaccatgcgggctgtgcggagacacctgttc
ccccagcactcagcccctggccgaggtgtcgtctgggagtggctgagcgacgatggctcc
tggactgcctatgaagccagcgtctgtgactatctggagcagcaggtggccaggggcaac
cagctcgtggacttggcccccctggggtacaactacactgtcaactacaccacccacacg
cagaccaacaagacttccagcttctgccgcagcgtgcggcgccaagcagggccgccttac
ccggtgaccaccatcatcgctccgccgggccacacaggcgtcgcctgctcttgccaccag
tgcctcagtggcagcagaactggccccgtgtcaggccgctaccgccactccatgaccaac
ctccctgcataccccgtcccccagcaccccccacacaggaccgcttctgtgtttgggacc
caccaggcctttgcaccgtacaacaaaccctcactctccggggcccggtctgcgcccagg
ctgaacaccaccaacgcctggggcgcagctcctccttccctggggagccagcccctctac
cgctccagcctctcccacctgggaccgcagcacctgcccccaggatcctccacctccggt
gcagtcagtgcctccctccccagcggtccctcaagcagcccagggagcgtccctgccact
gtgcccatgcagatgccaaagcccagcagagtccagcaggcgctcgcaggcatgacgagt
gttctgatgtcagccattggactccctgtgtgtcttagccgcgcaccccagcccaccagc
cctcccgcctcccgtctggcttccaaaagtcacggctcagttaagagattgaggaaaatg
tccgtgaaaggagcgaccccgaagccagagccagagccagagcaggtcataaaaaactac
acggaagagctgaaagtgcccccagatgaggactgcatcatctgcatggagaagctgtcc
acagcgtctggatacagcgatgtgactgacagcaaggcaatcgggtccctagctgtgggc
cacctcaccaagtgcagccatgccttccacctgctgtgcctcctggccatgtactgcaac
ggcaataaggatggaagtctgcagtgtccctcctgcaaaaccatctatggagagaagacg
gggacccagccccagggaaagatggaggtattacggttccagatgtcgctccccggccac
gaggactgcgggaccatcctcatagtttacagcattccccatggtatccagggccctgag
caccccaatcccggaaagccgttcactgccagagggtttccccgccagtgctaccttcca
gacaacgcccagggccgcaaggtcctagagctcctgaaggtggcctggaagaggcggctc
atcttcacagtgggcacgtccagcaccacgggtgagacggacaccgtggtatggaacgag
atccaccacaagacagagatggaccgcaacattacgggccacggctatcccgaccccaac
tacctgcagaacgtgctggctgagctggctgcccagggggtgaccgaggactgcctggag
cagcagtga

  All links  
Disease (1)   
   OMIM (1)   
Gene (33)   
   RefGene (23)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (5)   
   OC (1)   
Protein sequence (38)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (36)   
DNA sequence (72)   
   RefSeq(nuc) (36)   
   GenBank (18)   
   EMBL (18)   
3D Structure (4)   
   PDB (4)   
Protein domain (10)   
   Pfam (10)   
All databases (158)   

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