KEGG   Homo sapiens (human): 1215
Entry
1215              CDS       T01001                                 
Symbol
CMA1, CYH, MCT1, chymase
Name
(RefSeq) chymase 1
  KO
K01329  chymase [EC:3.4.21.39]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04614  Renin-angiotensin system
hsa05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09152 Endocrine system
   04614 Renin-angiotensin system
    1215 (CMA1)
 09160 Human Diseases
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    1215 (CMA1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    1215 (CMA1)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.39  chymase
     1215 (CMA1)
Peptidases and inhibitors [BR:hsa01002]
 Serine peptidases
  Family S1: chymotrypsin family
   1215 (CMA1)
SSDB
Motif
Pfam: Trypsin Trypsin_2 Peptidase_S29
Other DBs
NCBI-GeneID: 1215
NCBI-ProteinID: NP_001827
OMIM: 118938
HGNC: 2097
Ensembl: ENSG00000092009
UniProt: P23946 Q4FEB3
Structure
Position
14:complement(24505353..24508265)
AA seq 247 aa
MLLLPLPLLLFLLCSRAEAGEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNF
VLTAAHCAGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKA
SLTLAVGTLPFPSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRD
FDHNLQLCVGNPRKTKSAFKGDSGGPLLCAGVAQGIVSYGRSDAKPPAVFTRISHYRPWI
NQILQAN
NT seq 744 nt   +upstreamnt  +downstreamnt
atgctgcttcttcctctccccctgctgctctttctcttgtgctccagagctgaagctggg
gagatcatcgggggcacagaatgcaagccacattcccgcccctacatggcctacctggaa
attgtaacttccaacggtccctcaaaattttgtggtggtttccttataagacggaacttt
gtgctgacggctgctcattgtgcaggaaggtctataacagtcacccttggagcccataac
ataacagaggaagaagacacatggcagaagcttgaggttataaagcaattccgtcatcca
aaatataacacttctactcttcaccacgatatcatgttactaaagttgaaggagaaagcc
agcctgaccctggctgtggggacactccccttcccatcccaattcaactttgtcccacct
gggagaatgtgccgggtggctggctggggaagaacaggtgtgttgaagccgggctcagac
actctgcaagaggtgaagctgagactcatggatccccaggcctgcagccacttcagagac
tttgaccacaatcttcagctgtgtgtgggcaatcccaggaagacaaaatctgcatttaag
ggagactctgggggccctcttctgtgtgctggggtggcccagggcatcgtatcctatgga
cggtcggatgcaaagccccctgctgtcttcacccgaatctcccattaccggccctggatc
aaccagatcctgcaggcaaattaa

  All links  
Disease (1)   
   OMIM (1)   
Gene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (24)   
   RefSeq(nuc) (2)   
   GenBank (11)   
   EMBL (11)   
3D Structure (42)   
   PDB (42)   
Protein domain (3)   
   Pfam (3)   
All databases (80)   

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