KEGG   Homo sapiens (human): 1215
Entry
1215              CDS       T01001                                 
Symbol
CMA1, CYH, MCT1, chymase
Name
(RefSeq) chymase 1
  KO
K01329  chymase [EC:3.4.21.39]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04614  Renin-angiotensin system
hsa05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09152 Endocrine system
   04614 Renin-angiotensin system
    1215 (CMA1)
 09160 Human Diseases
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    1215 (CMA1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    1215 (CMA1)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.39  chymase
     1215 (CMA1)
Peptidases and inhibitors [BR:hsa01002]
 Serine peptidases
  Family S1: chymotrypsin family
   1215 (CMA1)
SSDB
Motif
Pfam: Trypsin Trypsin_2 Peptidase_S29
Other DBs
NCBI-GeneID: 1215
NCBI-ProteinID: NP_001827
OMIM: 118938
HGNC: 2097
Ensembl: ENSG00000092009
Pharos: P23946(Tchem)
UniProt: P23946 Q4FEB3
Structure
Position
14:complement(24505353..24508265)
AA seq 247 aa
MLLLPLPLLLFLLCSRAEAGEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNF
VLTAAHCAGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKA
SLTLAVGTLPFPSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRD
FDHNLQLCVGNPRKTKSAFKGDSGGPLLCAGVAQGIVSYGRSDAKPPAVFTRISHYRPWI
NQILQAN
NT seq 744 nt   +upstreamnt  +downstreamnt
atgctgcttcttcctctccccctgctgctctttctcttgtgctccagagctgaagctggg
gagatcatcgggggcacagaatgcaagccacattcccgcccctacatggcctacctggaa
attgtaacttccaacggtccctcaaaattttgtggtggtttccttataagacggaacttt
gtgctgacggctgctcattgtgcaggaaggtctataacagtcacccttggagcccataac
ataacagaggaagaagacacatggcagaagcttgaggttataaagcaattccgtcatcca
aaatataacacttctactcttcaccacgatatcatgttactaaagttgaaggagaaagcc
agcctgaccctggctgtggggacactccccttcccatcccaattcaactttgtcccacct
gggagaatgtgccgggtggctggctggggaagaacaggtgtgttgaagccgggctcagac
actctgcaagaggtgaagctgagactcatggatccccaggcctgcagccacttcagagac
tttgaccacaatcttcagctgtgtgtgggcaatcccaggaagacaaaatctgcatttaag
ggagactctgggggccctcttctgtgtgctggggtggcccagggcatcgtatcctatgga
cggtcggatgcaaagccccctgctgtcttcacccgaatctcccattaccggccctggatc
aaccagatcctgcaggcaaattaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (7)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
   PHAROS (1)   
Protein sequence (5)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (24)   
   RefSeq(nuc) (2)   
   GenBank (11)   
   EMBL (11)   
3D Structure (20)   
   PDB (20)   
Protein domain (3)   
   Pfam (3)   
All databases (67)   

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